Conjoint Professor Peter Greer

Conjoint Professor Peter Greer

Conjoint Professor

School of Mathematical and Physical Sciences (Physics)

Career Summary

Biography

Peter currently holds a full-time research position leading medical physics research at the Calvary Mater Newcastle Hospital and University of Newcastle. He graduated with a PhD in medical physics from the University of Adelaide in 2001. His work broadly aims to improve the treatment of cancer patients with radiation therapy and enable high quality effective treatments.

He has established a strong track record of translating research funding into successful outcomes. Several aspects of his research are currently being developed into commercial products for radiation oncology and medical imaging. He has received several awards including Early Career Researcher of the Year from the Hunter Medical Research Institute in 2011 - the premier award for early career medical research in the region. 

Research Expertise
Approximately half of all cancer patients receive radiation therapy. It is a major frontline treatment for cancer along with surgery and is often complemented by chemotherapy. High energy radiation beams are used to damage the DNA of cancer cells in solid tumours while minimising the normal tissue damage to surrounding organs. The radiation can be delivered externally using medical linear accelerators (teletherapy) or internally using radioactive sources (brachytherapy).

Modern radiation therapy is extremely sophisticated with imaging techniques such as MRI, CT, PET used for delineating tumour targets, complex dose calculation algorithms to plan the treatments and highly tailored dose distributions delivered using intensity modulated radiation beams. Medical physicists play a key role in all aspects of radiation oncology and drive the development of improved technology and techniques through research.

Peter has been conducting research since 2005 to improve radiation therapy planning with MRI. In collaboration with CSIRO Biomedical Imaging Research Group at the Australian E-Health Research Centre he has developed the first atlas-based deformable image registration method to map realistic electron densities to MRI scans for dose calculations. This could lead to the use of MRI scans directly for radiation oncology prostate planning and adaptive treatment to reduce uncertainties in the planning of treatments. He currently has an active research program using the state-of-the-art Calvary Mater 3T Skyra MRI scanner installed in April 2011 to improve radiation therapy planning. 

Peter is recognised as a world leader in the field of radiation dosimetry with flat-panel imaging devices, investigating methods to measure the dose received by patients during treatment. He has been twice the Scientific Director for the major international conference in radiotherapy treatment imaging. He has been awarded the Varian Prize for research in this field and is regularly invited to give presentations at national and international conferences and workshops. 

Teaching Expertise
Peter teaches medical physics courses at 4th year level. He has supervised many research higher degree students.

Administrative Expertise
Peter was Honorary Treasurer of the Australasian College of Physical Scientists and Engineers in Medicine, the professional body representing around 600 medical physicists and engineers working in medicine in Australia and New Zealand. He has been twice the Scientific Director for the major international conference in radiotherapy treatment imaging. He was Track Chair for the radiotherapy verification stream for the World Congress on Medical Physics and Bioengineering in 2012. Peter manages his own research group based at the Calvary Mater Newcastle, including staff supervision, management of budgets and reports.

Collaborations
Current collaborations include: - CSIRO E-Health Centre, Biomedical Imaging Group (MRI based treatment planning) - CancerCare Manitoba (Real-time dose verification of radiation therapy treatments) - University of Sydney (A/V Biofeedback for lung MRI imaging, dose verification for MRI-linac, Development of next-generation radiotherapy imaging devices)


Keywords

  • MRI based planning
  • dose verification
  • electronic portal imaging
  • medical physics

Fields of Research

Code Description Percentage
029903 Medical Physics 80
090399 Biomedical Engineering not elsewhere classified 10
110399 Clinical Sciences not elsewhere classified 10

Professional Experience

Membership

Dates Title Organisation / Department
Treasurer - Australasian College of Physical Scientists and Engineers in Medicine Australasian College of Physical Scientists and Engineers in Medicine
Australia
Ordinary Member - Australasian College of Physical Scientists and Engineers in Medicine Australasian College of Physical Scientists and Engineers in Medicine
Australia
1/03/2011 - 1/12/2011 Member NHMRC Grant Review Panel
Australia

Professional appointment

Dates Title Organisation / Department
Accredited Physicist Australasian College of Physical Scientists and Engineers in Medicine
Australia

Awards

Distinction

Year Award
2014 Fellowship of the ACPSEM
Australasian College Physical Scientists Engineers in Medicine

Research Award

Year Award
2010 Early Career Researcher of the Year
HMRI
2009 3D Segmentation Challenge for Clinical Applications
Medical Image Computing and Computer Assisted Intervention Society (MICCAI Society)
2007 Best presentation in Radiation therapy
Varian Medical Systems, Inc.

Invitations

Distinguished Visitor

Year Title / Rationale
2015 Invited Speaker - 3rd ESTRO Forum
Organisation: European Society for Radiation Oncology

Speaker

Year Title / Rationale
2012 EPID for pre-treatment VMAT verification
Organisation: International Conference on 3D Dosimetry
2012 EPID based QA
Organisation: World Congress on Medical Physics and Bioengineering
2012 33rd National Conference
Organisation: Association of Medical Physicists of India
2010 Challenges for Verification of IMRT
Organisation: 16th International Conference on Solid State Dosimetry
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Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Journal article (108 outputs)

Year Citation Altmetrics Link
2016 Barnes MP, Greer PB, 'Time-resolved beam symmetry measurement for VMAT commissioning and quality assurance.', J Appl Clin Med Phys, 17 6026 (2016)
2016 Lee D, Greer PB, Pollock S, Kim T, Keall P, 'Quantifying the accuracy of the tumor motion and area as a function of acceleration factor for the simulation of the dynamic keyhole magnetic resonance imaging method', Medical Physics, 43 2639-2648 (2016) [C1]

© 2016 American Association of Physicists in Medicine.Purpose: The dynamic keyhole is a newMRimage reconstruction method for thoracic and abdominal MR imaging. To date, this meth... [more]

© 2016 American Association of Physicists in Medicine.Purpose: The dynamic keyhole is a newMRimage reconstruction method for thoracic and abdominal MR imaging. To date, this method has not been investigated with cancer patient magnetic resonance imaging (MRI) data. The goal of this study was to assess the dynamic keyhole method for the task of lung tumor localization using cine-MR images reconstructed in the presence of respiratory motion. Methods: The dynamic keyhole method utilizes a previously acquired a library of peripheral k-space datasets at similar displacement and phase (where phase is simply used to determine whether the breathing is inhale to exhale or exhale to inhale) respiratory bins in conjunction with central k-space datasets (keyhole) acquired. External respiratory signals drive the process of sorting, matching, and combining the two k-space streams for each respiratory bin, thereby achieving faster image acquisition without substantial motion artifacts. This study was the first that investigates the impact of k-space undersampling on lung tumor motion and area assessment across clinically available techniques (zero-filling and conventional keyhole). In this study, the dynamic keyhole, conventional keyhole and zero-filling methods were compared to full k-space dataset acquisition by quantifying (1) the keyhole size required for central k-space datasets for constant image quality across sixty four cine-MRI datasets from nine lung cancer patients, (2) the intensity difference between the original and reconstructed images in a constant keyhole size, and (3) the accuracy of tumor motion and area directly measured by tumor autocontouring. Results: For constant image quality, the dynamic keyhole method, conventional keyhole, and zerofilling methods required 22%, 34%, and 49% of the keyhole size (P < 0.0001), respectively, compared to the full k-space image acquisition method. Compared to the conventional keyhole and zero-filling reconstructed images with the keyhole size utilized in the dynamic keyhole method, an average intensity difference of the dynamic keyhole reconstructed images (P < 0.0001) was minimal, and resulted in the accuracy of tumor motion within 99.6% (P < 0.0001) and the accuracy of tumor area within 98.0% (P < 0.0001) for lung tumor monitoring applications. Conclusions: This study demonstrates that the dynamic keyhole method is a promising technique for clinical applications such as image-guided radiation therapy requiring the MR monitoring of thoracic tumors. Based on the results from this study, the dynamic keyhole method could increase the imaging frequency by up to a factor of five compared with full k-space methods for real-time lung tumor MRI.

DOI 10.1118/1.4947508
Citations Scopus - 1
2016 Ghose S, Mitra J, Rivest-Hénault D, Fazlollahi A, Stanwell P, Pichler P, et al., 'MRI-alone radiation therapy planning for prostate cancer: Automatic fiducial marker detection.', Med Phys, 43 2218 (2016)
DOI 10.1118/1.4944871
Co-authors Peter Stanwell
2016 Fuangrod T, Greer PB, Woodruff HC, Simpson J, Bhatia S, Zwan B, et al., 'Investigation of a real-time EPID-based patient dose monitoring safety system using site-specific control limits.', Radiat Oncol, 11 106 (2016)
DOI 10.1186/s13014-016-0682-y
Co-authors Richard Middleton
2016 Lee D, Greer PB, Ludbrook J, Arm J, Hunter P, Pollock S, et al., 'Audiovisual Biofeedback Improves Cine-Magnetic Resonance Imaging Measured Lung Tumor Motion Consistency.', Int J Radiat Oncol Biol Phys, 94 628-636 (2016)
DOI 10.1016/j.ijrobp.2015.11.017
Citations Scopus - 2Web of Science - 2
2016 Seregni M, Paganelli C, Lee D, Greer PB, Baroni G, Keall PJ, Riboldi M, 'Motion prediction in MRI-guided radiotherapy based on interleaved orthogonal cine-MRI', Physics in Medicine and Biology, 61 872-887 (2016) [C1]

© 2016 Institute of Physics and Engineering in Medicine.In-room cine-MRI guidance can provide non-invasive target localization during radiotherapy treatment. However, in order to... [more]

© 2016 Institute of Physics and Engineering in Medicine.In-room cine-MRI guidance can provide non-invasive target localization during radiotherapy treatment. However, in order to cope with finite imaging frequency and system latencies between target localization and dose delivery, tumour motion prediction is required. This work proposes a framework for motion prediction dedicated to cine-MRI guidance, aiming at quantifying the geometric uncertainties introduced by this process for both tumour tracking and beam gating. The tumour position, identified through scale invariant features detected in cine-MRI slices, is estimated at high-frequency (25 Hz) using three independent predictors, one for each anatomical coordinate. Linear extrapolation, auto-regressive and support vector machine algorithms are compared against systems that use no prediction or surrogate-based motion estimation. Geometric uncertainties are reported as a function of image acquisition period and system latency. Average results show that the tracking error RMS can be decreased down to a [0.2; 1.2] mm range, for acquisition periods between 250 and 750 ms and system latencies between 50 and 300 ms. Except for the linear extrapolator, tracking and gating prediction errors were, on average, lower than those measured for surrogate-based motion estimation. This finding suggests that cine-MRI guidance, combined with appropriate prediction algorithms, could relevantly decrease geometric uncertainties in motion compensated treatments.

DOI 10.1088/0031-9155/61/2/872
Citations Scopus - 3Web of Science - 3
2016 Barnes MP, Rowshanfarzad P, Greer PB, 'VMAT linear accelerator commissioning and quality assurance: dose control and gantry speed tests.', J Appl Clin Med Phys, 17 6067 (2016)
2016 Chandra SS, Dowling JA, Greer PB, Martin J, Wratten C, Pichler P, et al., 'Fast automated segmentation of multiple objects via spatially weighted shape learning', PHYSICS IN MEDICINE AND BIOLOGY, 61 8070-8084 (2016)
DOI 10.1088/0031-9155/61/22/8070
2016 Loh J, Baker K, Sridharan S, Greer P, Wratten C, Capp A, et al., 'Re: Infections after Fiducial Marker Implantation for Prostate Radiotherapy: Are we Underestimating the Risks?', JOURNAL OF UROLOGY, 196 443-443 (2016)
2016 Kron T, Lehmann J, Greer PB, 'Dosimetry of ionising radiation in modern radiation oncology', PHYSICS IN MEDICINE AND BIOLOGY, 61 R167-R205 (2016) [C1]
DOI 10.1088/0031-9155/61/14/R167
2016 Zwan BJ, Barnes MP, Fuangord T, Stanton CJ, O'Connor DJ, Keall PJ, Greer PB, 'An EPID-based system for gantry-resolved MLC quality assurance for VMAT.', J Appl Clin Med Phys, 17 6312 (2016)
Co-authors John Oconnor
2016 Zwan BJ, Barnes MP, Fuangrod T, Stanton CJ, O'Connor DJ, Keall PJ, Greer PB, 'An EPID-based system for gantry-resolved MLC quality assurance for VMAT', JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS, 17 348-365 (2016)
Co-authors John Oconnor
2015 Loh J, Baker K, Sridharan S, Greer P, Wratten C, Capp A, et al., 'Infections after fiducial marker implantation for prostate radiotherapy: are we underestimating the risks?', RADIATION ONCOLOGY, 10 (2015) [C1]
DOI 10.1186/s13014-015-0347-2
Citations Scopus - 2Web of Science - 1
Co-authors Jarad Martin
2015 Van Uytven E, Van Beek T, McCowan PM, Chytyk-Praznik K, Greer PB, McCurdy BMC, 'Validation of a method for in vivo 3D dose reconstruction for IMRT and VMAT treatments using on-treatment EPID images and a model-based forward-calculation algorithm', Medical Physics, 42 6945-6954 (2015) [C1]

© 2015 American Association of Physicists in Medicine.Purpose: Radiation treatments are trending toward delivering higher doses per fraction under stereotactic radiosurgery and h... [more]

© 2015 American Association of Physicists in Medicine.Purpose: Radiation treatments are trending toward delivering higher doses per fraction under stereotactic radiosurgery and hypofractionated treatment regimens. There is a need for accurate 3D in vivo patient dose verification using electronic portal imaging device (EPID) measurements. This work presents a model-based technique to compute full three-dimensional patient dose reconstructed from on-treatment EPID portal images (i.e., transmission images). Methods: EPID dose is converted to incident fluence entering the patient using a series of steps which include converting measured EPID dose to fluence at the detector plane and then back-projecting the primary source component of the EPID fluence upstream of the patient. Incident fluence is then recombined with predicted extra-focal fluence and used to calculate 3D patient dose via a collapsed-cone convolution method. This method is implemented in an iterative manner, although in practice it provides accurate results in a single iteration. The robustness of the dose reconstruction technique is demonstrated with several simple slab phantom and nine anthropomorphic phantom cases. Prostate, head and neck, and lung treatments are all included as well as a range of delivery techniques including VMAT and dynamic intensity modulated radiation therapy (IMRT). Results: Results indicate that the patient dose reconstruction algorithm compares well with treatment planning system computed doses for controlled test situations. For simple phantom and square field tests, agreement was excellent with a 2%/2 mm 3D chi pass rate .98.9%. On anthropomorphic phantoms, the 2%/2 mm 3D chi pass rates ranged from 79.9% to 99.9% in the planning target volume (PTV) region and 96.5% to 100% in the low dose region (>20% of prescription, excluding PTV and skin build-up region). Conclusions: An algorithm to reconstruct delivered patient 3D doses from EPID exit dosimetry measurements was presented. The method was applied to phantom and patient data sets, as well as for dynamic IMRT and VMAT delivery techniques. Results indicate that the EPID dose reconstruction algorithm presented in this work is suitable for clinical implementation.

DOI 10.1118/1.4935199
Citations Scopus - 5Web of Science - 5
2015 Herschtal A, te Marvelde L, Mengersen K, Hosseinifard Z, Foroudi F, Devereux T, et al., 'Calculating radiotherapy margins based on Bayesian modelling of patient specific random errors', PHYSICS IN MEDICINE AND BIOLOGY, 60 1793-1805 (2015) [C1]
DOI 10.1088/0031-9155/60/5/1793
2015 Dowling JA, Sun J, Pichler P, Rivest-Hénault D, Ghose S, Richardson H, et al., 'Automatic substitute computed tomography generation and contouring for magnetic resonance imaging (MRI)-alone external beam radiation therapy from standard MRI sequences', International Journal of Radiation Oncology Biology Physics, 93 1144-1153 (2015) [C1]

Crown Copyright © 2015 Published by Elsevier Inc. All rights reserved.Purpose To validate automatic substitute computed tomography CT (sCT) scans generated from standard T2-weigh... [more]

Crown Copyright © 2015 Published by Elsevier Inc. All rights reserved.Purpose To validate automatic substitute computed tomography CT (sCT) scans generated from standard T2-weighted (T2w) magnetic resonance (MR) pelvic scans for MR-Sim prostate treatment planning. Patients and Methods A Siemens Skyra 3T MR imaging (MRI) scanner with laser bridge, flat couch, and pelvic coil mounts was used to scan 39 patients scheduled for external beam radiation therapy for localized prostate cancer. For sCT generation a whole-pelvis MRI scan (1.6 mm 3-dimensional isotropic T2w SPACE [Sampling Perfection with Application optimized Contrasts using different flip angle Evolution] sequence) was acquired. Three additional small field of view scans were acquired: T2w, T2*w, and T1w flip angle 80° for gold fiducials. Patients received a routine planning CT scan. Manual contouring of the prostate, rectum, bladder, and bones was performed independently on the CT and MR scans. Three experienced observers contoured each organ on MRI, allowing interobserver quantification. To generate a training database, each patient CT scan was coregistered to their whole-pelvis T2w using symmetric rigid registration and structure-guided deformable registration. A new multi-atlas local weighted voting method was used to generate automatic contours and sCT results. Results The mean error in Hounsfield units between the sCT and corresponding patient CT (within the body contour) was 0.6 ± 14.7 (mean ± 1 SD), with a mean absolute error of 40.5 ± 8.2 Hounsfield units. Automatic contouring results were very close to the expert interobserver level (Dice similarity coefficient): prostate 0.80 ± 0.08, bladder 0.86 ± 0.12, rectum 0.84 ± 0.06, bones 0.91 ± 0.03, and body 1.00 ± 0.003. The change in monitor units between the sCT-based plans relative to the gold standard CT plan for the same dose prescription was found to be 0.3% ± 0.8%. The 3-dimensional ¿ pass rate was 1.00 ± 0.00 (2 mm/2%). Conclusions The MR-Sim setup and automatic sCT generation methods using standard MR sequences generates realistic contours and electron densities for prostate cancer radiation therapy dose planning and digitally reconstructed radiograph generation.

DOI 10.1016/j.ijrobp.2015.08.045
Citations Scopus - 5Web of Science - 1
Co-authors Fred Menk, Jarad Martin
2015 Loh J, Baker K, Sridharan S, Greer P, Wratten C, Capp A, et al., 'Infections after fiducial marker implantation for prostate radiotherapy: are we underestimating the risks?', Radiation oncology (London, England), 10 38 (2015)
2015 Paganelli C, Lee D, Greer PB, Baroni G, Riboldi M, Keall P, 'Quantification of lung tumor rotation with automated landmark extraction using orthogonal cine MRI images', Physics in Medicine and Biology, 60 7165-7178 (2015) [C1]

© 2015 Institute of Physics and Engineering in Medicine.The quantification of tumor motion in sites affected by respiratory motion is of primary importance to improve treatment a... [more]

© 2015 Institute of Physics and Engineering in Medicine.The quantification of tumor motion in sites affected by respiratory motion is of primary importance to improve treatment accuracy. To account for motion, different studies analyzed the translational component only, without focusing on the rotational component, which was quantified in a few studies on the prostate with implanted markers. The aim of our study was to propose a tool able to quantify lung tumor rotation without the use of internal markers, thus providing accurate motion detection close to critical structures such as the heart or liver. Specifically, we propose the use of an automatic feature extraction method in combination with the acquisition of fast orthogonal cine MRI images of nine lung patients. As a preliminary test, we evaluated the performance of the feature extraction method by applying it on regions of interest around (i) the diaphragm and (ii) the tumor and comparing the estimated motion with that obtained by (i) the extraction of the diaphragm profile and (ii) the segmentation of the tumor, respectively. The results confirmed the capability of the proposed method in quantifying tumor motion. Then, a point-based rigid registration was applied to the extracted tumor features between all frames to account for rotation. The median lung rotation values were -0.6 ± 2.3° and -1.5 ± 2.7° in the sagittal and coronal planes respectively, confirming the need to account for tumor rotation along with translation to improve radiotherapy treatment.

DOI 10.1088/0031-9155/60/18/7165
Citations Scopus - 1Web of Science - 1
2015 Rivest-Hénault D, Dowson N, Greer PB, Fripp J, Dowling JA, 'Robust inverse-consistent affine CT-MR registration in MRI-assisted and MRI-alone prostate radiation therapy', Medical Image Analysis, 23 56-69 (2015) [C1]

© 2015.Background: CT-MR registration is a critical component of many radiation oncology protocols. In prostate external beam radiation therapy, it allows the propagation of MR-d... [more]

© 2015.Background: CT-MR registration is a critical component of many radiation oncology protocols. In prostate external beam radiation therapy, it allows the propagation of MR-derived contours to reference CT images at the planning stage, and it enables dose mapping during dosimetry studies. The use of carefully registered CT-MR atlases allows the estimation of patient specific electron density maps from MRI scans, enabling MRI-alone radiation therapy planning and treatment adaptation. In all cases, the precision and accuracy achieved by registration influences the quality of the entire process.Problem: Most current registration algorithms do not robustly generalize and lack inverse-consistency, increasing the risk of human error and acting as a source of bias in studies where information is propagated in a particular direction, e.g. CT to MR or vice versa. In MRI-based treatment planning where both CT and MR scans serve as spatial references, inverse-consistency is critical, if under-acknowledged.Purpose: A robust, inverse-consistent, rigid/affine registration algorithm that is well suited to CT-MR alignment in prostate radiation therapy is presented.Method: The presented method is based on a robust block-matching optimization process that utilises a half-way space definition to maintain inverse-consistency. Inverse-consistency substantially reduces the influence of the order of input images, simplifying analysis, and increasing robustness. An open source implementation is available online at http://aehrc.github.io/Mirorr/.Results: Experimental results on a challenging 35 CT-MR pelvis dataset demonstrate that the proposed method is more accurate than other popular registration packages and is at least as accurate as the state of the art, while being more robust and having an order of magnitude higher inverse-consistency than competing approaches.Conclusion: The presented results demonstrate that the proposed registration algorithm is readily applicable to prostate radiation therapy planning.

DOI 10.1016/j.media.2015.04.014
Citations Scopus - 8Web of Science - 7
2015 Sun J, Dowling JA, Pichler P, Parker J, Martin J, Stanwell P, et al., 'Investigation on the performance of dedicated radiotherapy positioning devices for MR scanning for prostate planning', Journal of Applied Clinical Medical Physics, 16 4-13 (2015) [C1]

The purpose of this study was to investigate performance of the couch and coil mounts designed for MR-simulation prostate scanning using data from ten volunteers. Volunteers were ... [more]

The purpose of this study was to investigate performance of the couch and coil mounts designed for MR-simulation prostate scanning using data from ten volunteers. Volunteers were scanned using the standard MR scanning protocol with the MR coil directly strapped on the external body and the volunteer lying on the original scanner table. They also were scanned using a MR-simulation table top and pelvic coil mounts. MR images from both setups were compared in terms of body contour variation and image quality effects within particular organs of interest. Six-field conformal plans were generated on the two images with assigned bulk density for dose calculation. With the MR-simulation devices, the anterior skin deformation was reduced by up to 1.7 cm. The hard tabletop minimizes the posterior body deformation which can be up to 2.3 cm on the standard table, depending on the weight of volunteer. The image signal-to-noise ratio reduced by 14% and 25% on large field of view (FOV) and small FOV images, respectively, after using the coil mount; the prostate volume contoured on two images showed difference of 1.05 ± 0.66 cm3. The external body deformation caused a mean dose reduction of 0.6 ± 0.3 Gy, while the coverage reduced by 22% ± 13% and 27% ± 6% in V98 and V100, respectively. A dedicated MR simulation setup for prostate radiotherapy is essential to ensure the agreement between planning anatomy and treatment anatomy. The image signal was reduced after applying the coil mount, but no significant effect was found on prostate contouring.

DOI 10.1120/jacmp.v16i2.4848
Co-authors Peter Stanwell, Jarad Martin, Fred Menk
2015 Sun J, Dowling J, Pichler P, Menk F, Rivest-Henault D, Lambert J, et al., 'MRI simulation: End-to-end testing for prostate radiation therapy using geometric pelvic MRI phantoms', Physics in Medicine and Biology, 60 3097-3109 (2015) [C1]

© 2015 Institute of Physics and Engineering in Medicine.To clinically implement MRI simulation or MRI-alone treatment planning requires comprehensive end-to-end testing to ensure... [more]

© 2015 Institute of Physics and Engineering in Medicine.To clinically implement MRI simulation or MRI-alone treatment planning requires comprehensive end-to-end testing to ensure an accurate process. The purpose of this study was to design and build a geometric phantom simulating a human male pelvis that is suitable for both CT and MRI scanning and use it to test geometric and dosimetric aspects of MRI simulation including treatment planning and digitally reconstructed radiograph (DRR) generation. A liquid filled pelvic shaped phantom with simulated pelvic organs was scanned in a 3T MRI simulator with dedicated radiotherapy couch-top, laser bridge and pelvic coil mounts. A second phantom with the same external shape but with an internal distortion grid was used to quantify the distortion of the MR image. Both phantoms were also CT scanned as the gold-standard for both geometry and dosimetry. Deformable image registration was used to quantify the MR distortion. Dose comparison was made using a seven-field IMRT plan developed on the CT scan with the fluences copied to the MR image and recalculated using bulk electron densities. Without correction the maximum distortion of the MR compared with the CT scan was 7.5 mm across the pelvis, while this was reduced to 2.6 and 1.7 mm by the vendor's 2D and 3D correction algorithms, respectively. Within the locations of the internal organs of interest, the distortion was <1.5 and <1 mm with 2D and 3D correction algorithms, respectively. The dose at the prostate isocentre calculated on CT and MRI images differed by 0.01% (1.1 cGy). Positioning shifts were within 1 mm when setup was performed using MRI generated DRRs compared to setup using CT DRRs. The MRI pelvic phantom allows end-to-end testing of the MRI simulation workflow with comparison to the gold-standard CT based process. MRI simulation was found to be geometrically accurate with organ dimensions, dose distributions and DRR based setup within acceptable limits compared to CT.

DOI 10.1088/0031-9155/60/8/3097
Citations Scopus - 5Web of Science - 4
Co-authors Jarad Martin, Fred Menk, Jim Denham
2015 Whelan B, Kumar S, Dowling J, Begg J, Lambert J, Lim K, et al., 'Utilising pseudo-CT data for dose calculation and plan optimization in adaptive radiotherapy', Australasian Physical and Engineering Sciences in Medicine, (2015) [C1]

© 2015 Australasian College of Physical Scientists and Engineers in Medicine To quantify the dose calculation error and resulting optimization uncertainty caused by performing in... [more]

© 2015 Australasian College of Physical Scientists and Engineers in Medicine To quantify the dose calculation error and resulting optimization uncertainty caused by performing inverse treatment planning on inaccurate electron density data (pseudo-CT) as needed for adaptive radiotherapy and Magnetic Resonance Imaging (MRI) based treatment planning. Planning Computer Tomography (CT) data from 10 cervix cancer patients was used to generate 4 pseudo-CT data sets. Each pseudo-CT was created based on an available method of assigning electron density to an anatomic image. An inversely modulated radiotherapy (IMRT) plan was developed on each planning CT. The dose calculation error caused by each pseudo-CT data set was quantified by comparing the dose calculated each pseudo-CT data set with that calculated on the original planning CT for the same IMRT plan. The optimization uncertainty introduced by the dose calculation error was quantified by re-optimizing the same optimization parameters on each pseudo-CT data set and comparing against the original planning CT. Dose differences were quantified by assessing the Equivalent Uniform Dose (EUD) for targets and relevant organs at risk. Across all pseudo-CT data sets and all organs, the absolute mean dose calculation error was 0.2 Gy, and was within 2 % of the prescription dose in 98.5 % of cases. Then absolute mean optimisation error was 0.3 Gy EUD, indicating that that inverse optimisation is impacted by the dose calculation error. However, the additional uncertainty introduced to plan optimisation is small compared the sources of variation which already exist. Use of inaccurate electron density data for inverse treatment planning results in a dose calculation error, which in turn introduces additional uncertainty into the plan optimization process. In this study, we showed that both of these effects are clinically acceptable for cervix cancer patients using four different pseudo-CT data sets. Dose calculation and inverse optimization on pseudo-CT is feasible for this patient cohort.

DOI 10.1007/s13246-015-0376-z
2015 Fuangrod T, Rowshanfarzad P, Greer PB, Middleton RH, 'A cine-EPID based method for jaw detection and quality assurance for tracking jaw in IMRT/VMAT treatments', Physica Medica, 31 16-24 (2015) [C1]

© 2014 Associazione Italiana di Fisica Medica.A new tool with the potential to verify and track jaw position during delivery has been developed. The method should be suitable for... [more]

© 2014 Associazione Italiana di Fisica Medica.A new tool with the potential to verify and track jaw position during delivery has been developed. The method should be suitable for independent quality assurance for jaw position during jaw tracking dynamic IMRT and VMAT treatments. The jaw detection and tracking algorithm developed consists of five main steps. Firstly, the image is enhanced by removing a normalised predicted EPID image (that does not include the collimator transmission) from each cine EPID image. Then, using a histogram clustering technique a global intensity threshold level was determined. This threshold level was used to classify each pixel of the image as either under the jaws or under the MLC. Additionally, the collimator angle was automatically detected and used to rotate the image to vertical direction. Finally, this rotation allows the jaw positions to be determined using vertical and horizontal projection profiles. Nine IMRT fields (with static jaws) and a single VMAT clinical field (with dynamic jaws) were tested by determining the root mean square difference between planned and detected jaw positions. The test results give a detection accuracy of ±1mm RMS error for static jaw IMRT treatments and ±1.5mm RMS error for the dynamic jaw VMAT treatment. This method is designed for quality assurance and verification in modern radiation therapy; to detect the position of static jaws or verify the position of tracking jaws in more complex treatments. This method uses only information extracted from EPID images and it is therefore independent from the linear accelerator.

DOI 10.1016/j.ejmp.2014.11.002
Citations Scopus - 6Web of Science - 6
Co-authors Richard Middleton
2015 Sun J, Barnes M, Dowling J, Menk F, Stanwell P, Greer PB, 'An open source automatic quality assurance (OSAQA) tool for the ACR MRI phantom.', Australas Phys Eng Sci Med, 38 39-46 (2015) [C1]
DOI 10.1007/s13246-014-0311-8
Co-authors Peter Stanwell, Fred Menk
2015 Woodruff HC, Fuangrod T, Van Uytven E, McCurdy BMC, Van Beek T, Bhatia S, Greer PB, 'First Experience with Real-Time EPID-Based Delivery Verification during IMRT and VMAT Sessions', International Journal of Radiation Oncology Biology Physics, 93 516-522 (2015) [C1]

© 2015 Elsevier Inc. All rights reserved.Purpose Gantry-mounted megavoltage electronic portal imaging devices (EPIDs) have become ubiquitous on linear accelerators. WatchDog is a... [more]

© 2015 Elsevier Inc. All rights reserved.Purpose Gantry-mounted megavoltage electronic portal imaging devices (EPIDs) have become ubiquitous on linear accelerators. WatchDog is a novel application of EPIDs, in which the image frames acquired during treatment are used to monitor treatment delivery in real time. We report on the preliminary use of WatchDog in a prospective study of cancer patients undergoing intensity modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) and identify the challenges of clinical adoption. Methods and Materials At the time of submission, 28 cancer patients (head and neck, pelvis, and prostate) undergoing fractionated external beam radiation therapy (24 IMRT, 4 VMAT) had =1 treatment fraction verified in real time (131 fractions or 881 fields). EPID images acquired continuously during treatment were synchronized and compared with model-generated transit EPID images within a frame time (~0.1 s). A ¿ comparison was performed to cumulative frames to gauge the overall delivery quality, and the resulting pass rates were reported graphically during treatment delivery. Every frame acquired (500-1500 per fraction) was saved for postprocessing and analysis. Results The system reported the mean ± standard deviation in real time ¿ 91.1% ± 11.5% (83.6% ± 13.2%) for cumulative frame ¿ analysis with 4%, 4 mm (3%, 3 mm) criteria, global over the integrated image. Conclusions A real-time EPID-based radiation delivery verification system for IMRT and VMAT has been demonstrated that aims to prevent major mistreatments in radiation therapy.

DOI 10.1016/j.ijrobp.2015.07.2271
Citations Scopus - 5Web of Science - 4
2014 Sun J, Pichler P, Dowling J, Menk F, Stanwell P, Arm J, Greer PB, 'MR simulation for prostate radiation therapy: Effect of coil mounting position on image quality', British Journal of Radiology, 87 (2014) [C1]

© 2014 The Authors.Methods: A custom-designed pelvic-shaped phantom was scanned by systematically increasing the anterior body-tocoil (BTC) distance from 30 to 90mm. The image qu... [more]

© 2014 The Authors.Methods: A custom-designed pelvic-shaped phantom was scanned by systematically increasing the anterior body-tocoil (BTC) distance from 30 to 90mm. The image quality near the organs of interest was determined in order to characterize the relationship between image quality and BTC distance at the critical organ structures. The half intensity reduction (HIR) was calculated to determine the sensitivity of each organ structure to the BTC distance change.Advances in knowledge: A method to characterize the effect on image quality due to the use of coil mounts was demonstrated. Coil mounts whose height can be adjusted individually to keep BTC distance constant are necessary to maintain a uniform image across the entire field of view.Results: As the BTC distance increased, the uniformity reduced at 3% per millimetre. The HIR value indicated that the bladder signal is most sensitive to the change in BTC distance. By maintaining a constant BTC distance set-up, the intensity uniformitywas improved by 28% along the B0 directions.Conclusion: Positioning the MRI coil on mounts can reduce body deformation but adversely degrades the image quality. The magnitude of this effect has been quantified for prostate MR simulation scanning. The coil needs to be positioned not only with a minimal but also uniform BTC distance in order to maximize image quality.Objective: To eliminate the effects of body deformation for MR-based prostate treatment planning, coil mounts are essential. In this study, we evaluated the effect of the coil set-up on image quality.

DOI 10.1259/bjr.20140325
Citations Scopus - 2Web of Science - 1
Co-authors Peter Stanwell, Fred Menk
2014 Fuangrod T, Woodruff HC, Rowshanfarzad P, O'Connor DJ, Middleton RH, Greer PB, 'An independent system for real-time dynamic multileaf collimation trajectory verification using EPID', PHYSICS IN MEDICINE AND BIOLOGY, 59 61-81 (2014) [C1]
DOI 10.1088/0031-9155/59/1/61
Citations Scopus - 6Web of Science - 4
Co-authors Richard Middleton, John Oconnor
2014 Zwan BJ, King BW, O'Connor DJ, Greer PB, 'Dose-to-water conversion for the backscatter-shielded EPID: a frame-based method to correct for EPID energy response to MLC transmitted radiation.', Med Phys, 41 081716 (2014) [C1]
DOI 10.1118/1.4890677
Co-authors John Oconnor
2014 Sabet M, Rowshanfarzad P, Menk FW, Greer PB, 'Transit dosimetry in dynamic IMRT with an a-Si EPID', MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING, 52 579-588 (2014) [C1]
DOI 10.1007/s11517-014-1161-y
Citations Scopus - 2Web of Science - 2
Co-authors Fred Menk
2014 Rivest-Hénault D, Dowson N, Greer P, Dowling J, 'Inverse-consistent rigid registration of CT and MR for MR-based planning and adaptive prostate radiation therapy', Journal of Physics: Conference Series, 489 (2014)

MRI-alone treatment planning and adaptive MRI-based prostate radiation therapy are two promising techniques that could significantly increase the accuracy of the curative dose del... [more]

MRI-alone treatment planning and adaptive MRI-based prostate radiation therapy are two promising techniques that could significantly increase the accuracy of the curative dose delivery processes while reducing the total radiation dose. State-of-the-art methods rely on the registration of a patient MRI with a MR-CT atlas for the estimation of pseudo-CT [5]. This atlas itself is generally created by registering many CT and MRI pairs. Most registration methods are not symmetric, but the order of the images influences the result [8]. The computed transformation is therefore biased, introducing unwanted variability. This work examines how much a symmetric algorithm improves the registration. Methods: A robust symmetric registration algorithm is proposed that simultaneously optimises a half space transform and its inverse. During the registration process, the two input volumetric images are transformed to a common position in space, therefore minimising any computational bias. An asymmetrical implementation of the same algorithm was used for comparison purposes. Results: Whole pelvis MRI and CT scans from 15 prostate patients were registered, as in the creation of MR-CT atlases. In each case, two registrations were performed, with different input image orders, and the transformation error quantified. Mean residuals of 0.63±0.26 mm (translation) and (8.7±7.3) × 10-3 rad (rotation) were found for the asymmetrical implementation with corresponding values of 0.038±0.039 mm and (1.6 ± 1.3) × 10-3 rad for the proposed symmetric algorithm, a substantial improvement. Conclusions: The increased registration precision will enhance the generation of pseudo-CT from MRI for atlas based MR planning methods. © Published under licence by IOP Publishing Ltd.

DOI 10.1088/1742-6596/489/1/012039
Citations Scopus - 7
2014 Ghose S, Holloway L, Lim K, Chan P, Veera J, Vinod SK, et al., 'A review of segmentation and deformable registration methods applied to adaptive cervical cancer radiation therapy treatment planning', Artificial Intelligence in Medicine, (2014) [C1]

Objective: Manual contouring and registration for radiotherapy treatment planning and online adaptation for cervical cancer radiation therapy in computed tomography (CT) and magne... [more]

Objective: Manual contouring and registration for radiotherapy treatment planning and online adaptation for cervical cancer radiation therapy in computed tomography (CT) and magnetic resonance images (MRI) are often necessary. However manual intervention is time consuming and may suffer from inter or intra-rater variability. In recent years a number of computer-guided automatic or semi-automatic segmentation and registration methods have been proposed. Segmentation and registration in CT and MRI for this purpose is a challenging task due to soft tissue deformation, inter-patient shape and appearance variation and anatomical changes over the course of treatment. The objective of this work is to provide a state-of-the-art review of computer-aided methods developed for adaptive treatment planning and radiation therapy planning for cervical cancer radiation therapy. Methods: Segmentation and registration methods published with the goal of cervical cancer treatment planning and adaptation have been identified from the literature (PubMed and Google Scholar). A comprehensive description of each method is provided. Similarities and differences of these methods are highlighted and the strengths and weaknesses of these methods are discussed. A discussion about choice of an appropriate method for a given modality is provided. Results: In the reviewed papers a Dice similarity coefficient of around 0.85 along with mean absolute surface distance of 2-4. mm for the clinically treated volume were reported for transfer of contours from planning day to the treatment day. Conclusions: Most segmentation and non-rigid registration methods have been primarily designed for adaptive re-planning for the transfer of contours from planning day to the treatment day. The use of shape priors significantly improved segmentation and registration accuracy compared to other models.

DOI 10.1016/j.artmed.2015.04.006
Citations Scopus - 4Web of Science - 2
2014 McCowan PM, Rickey DW, Rowshanfarzad P, Greer PB, Ansbacher W, McCurdy BM, 'An investigation of gantry angle data accuracy for cine-mode EPID images acquired during arc IMRT', Journal of Applied Clinical Medical Physics, 15 187-201 (2014) [C1]
Citations Scopus - 8Web of Science - 7
2014 Monville ME, Kuncic Z, Greer PB, 'Simulation of real-time EPID images during IMRT using Monte-Carlo', PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS, 30 326-330 (2014) [C1]
DOI 10.1016/j.ejmp.2013.10.002
Citations Scopus - 2Web of Science - 1
2014 Dowling JA, Burdett N, Greer PB, Sun J, Parker J, Pichler P, et al., 'Automatic Atlas Based Electron Density and Structure Contouring for MRI-based Prostate Radiation Therapy on the Cloud', Journal of Physics: Conference Series, 489 (2014) [E1]

Our group have been developing methods for MRI-alone prostate cancer radiation therapy treatment planning. To assist with clinical validation of the workflow we are investigating ... [more]

Our group have been developing methods for MRI-alone prostate cancer radiation therapy treatment planning. To assist with clinical validation of the workflow we are investigating a cloud platform solution for research purposes. Benefits of cloud computing can include increased scalability, performance and extensibility while reducing total cost of ownership. In this paper we demonstrate the generation of DICOM-RT directories containing an automatic average atlas based electron density image and fast pelvic organ contouring from whole pelvis MR scans. © Published under licence by IOP Publishing Ltd.

DOI 10.1088/1742-6596/489/1/012048
Citations Scopus - 2Web of Science - 2
Co-authors Peter Stanwell
2014 Lee D, Greer PB, Arm J, Keall P, Kim T, 'Audiovisual biofeedback improves image quality and reduces scan time for respiratory-gated 3D MRI', Journal of Physics: Conference Series, 489 1-4 (2014) [E1]
DOI 10.1088/1742-6596/489/1/012033
Citations Scopus - 6
2014 Blake SJ, McNamara AL, Vial P, Holloway L, Greer PB, Kuncic Z, 'Monte Carlo simulation of the transit dosimetric response of an a-Si electronic portal imaging device', Journal of Physics: Conference Series, 489 1-6 (2014) [C1]
DOI 10.1088/1742-6596/489/1/012005
Citations Scopus - 2
2014 Monville ME, Kuncic Z, Greer PB, 'An improved Monte-Carlo model of the Varian EPID separating support arm and rear-housing backscatter', XVII INTERNATIONAL CONFERENCE ON THE USE OF COMPUTERS IN RADIATION THERAPY (ICCR 2013), 489 (2014) [E1]
DOI 10.1088/1742-6596/489/1/012012
2013 Blake SJ, Vial P, Holloway L, Greer PB, McNamara AL, Kuncic Z, 'Characterization of optical transport effects on EPID dosimetry using Geant4', MEDICAL PHYSICS, 40 (2013) [C1]
DOI 10.1118/1.4794479
Citations Scopus - 7Web of Science - 6
2013 Woodruff HC, Fuangrod T, Rowshanfarzad P, McCurdy BMC, Greer PB, 'Gantry-angle resolved VMAT pretreatment verification using EPID image prediction', MEDICAL PHYSICS, 40 (2013) [C1]
DOI 10.1118/1.4816384
Citations Scopus - 19Web of Science - 17
2013 Blake SJ, McNamara AL, Deshpande S, Holloway L, Greer PB, Kuncic Z, Vial P, 'Characterization of a novel EPID designed for simultaneous imaging and dose verification in radiotherapy', MEDICAL PHYSICS, 40 (2013) [C1]
DOI 10.1118/1.4816657
Citations Scopus - 4Web of Science - 5
2013 Fuangrod T, Woodruff HC, Van Uytven E, McCurdy BMC, Kuncic Z, O'Connor DJ, Greer PB, 'A system for EPID-based real-time treatment delivery verification during dynamic IMRT treatment', Medical Physics, 40 (2013) [C1]
DOI 10.1118/1.4817484
Citations Scopus - 14Web of Science - 12
Co-authors John Oconnor
2013 Chytyk-Praznik K, VanUytven E, vanBeek TA, Greer PB, McCurdy BMC, 'Model-based prediction of portal dose images during patient treatment', Medical Physics, 40 (2013) [C1]
DOI 10.1118/1.4792203
Citations Scopus - 13Web of Science - 12
2013 King BW, Greer PB, 'A method for removing arm backscatter from EPID images', Medical Physics, 40 (2013) [C1]
DOI 10.1118/1.4807640
Citations Scopus - 2Web of Science - 1
2013 McNamara AL, Blake SJ, Vial P, Holloway L, Greer PB, Kuncic Z, 'Evaluating radiation damage to scintillating plastic fibers with Monte Carlo simulations', MEDICAL IMAGING 2013: PHYSICS OF MEDICAL IMAGING, 8668 (2013) [E1]
DOI 10.1117/12.2007819
2013 Ghose S, Holloway L, Lim K, Chan P, Veera J, Vinod SK, et al., 'A survey of cervix segmentation methods in magnetic resonance images', Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), 8198 LNCS 290-298 (2013) [C1]

Radiotherapy is an effective therapy in the treatment of cervix cancer. However tumor and normal tissue motion and shape deformation of the cervix, the bladder and the rectum over... [more]

Radiotherapy is an effective therapy in the treatment of cervix cancer. However tumor and normal tissue motion and shape deformation of the cervix, the bladder and the rectum over the course of the treatment can limit the efficacy of radiotherapy and safe delivery of the dose. A number of studies have presented the potential benefits of adaptive radiotherapy for cervix cancer with high soft tissue contrast magnetic resonance images. To enable practical implementation of adaptive radiotherapy for the cervix, computer aided segmentation is necessary. Accurate computer aided automatic or semi-automatic segmentation of the cervix is a challenging task due to inter patient shape variation, soft tissue deformation, organ motion, and anatomical changes during the course of the treatment. This article reviews the methods developed for cervix segmentation in magnetic resonance images. The objective of this work is to present different methods for cervix segmentation in the literature highlighting their similarities, differences, strengths and weaknesses. © 2013 Springer-Verlag.

DOI 10.1007/978-3-642-41083-3_32
2013 Singh J, Greer PB, White MA, Parker J, Patterson J, Tang CI, et al., 'Treatment-Related Morbidity in Prostate Cancer: A Comparison of 3-Dimensional Conformal Radiation Therapy With and Without Image Guidance Using Implanted Fiducial Markers', INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 85 1018-1023 (2013) [C1]
DOI 10.1016/j.ijrobp.2012.07.2376
Citations Scopus - 17Web of Science - 15
Co-authors Jim Denham
2013 Woodruff HC, Greer PB, '3D Dose reconstruction: Banding artefacts in cine mode EPID images during VMAT delivery', Journal of Physics: Conference Series, 444 012042 (2013) [E1]
DOI 10.1088/1742-6596/444/1/012042
Citations Scopus - 2Web of Science - 1
2012 Rowshan Farzad P, Sabet M, O'Connor JD, Greer PB, 'Investigation of the sag in linac secondary collimator and MLC carriage during arc deliveries', Physics in Medicine and Biology, 57 N209-N224 (2012) [C1]
Citations Scopus - 10Web of Science - 8
Co-authors John Oconnor
2012 Herschtal A, Foroudi F, Greer PB, Eade TN, Hindson BR, Kron T, 'Finding the optimal statistical model to describe target motion during radiotherapy delivery-a Bayesian approach', Physics in Medicine and Biology, 57 2743-2755 (2012) [C1]
Citations Scopus - 4Web of Science - 3
2012 Sabet M, Rowshan Farzad P, Vial P, Menk FW, Greer PB, 'Transit dosimetry in IMRT with an a-Si EPID in direct detection configuration', Physics in Medicine and Biology, 57 N295-N306 (2012) [C1]
Citations Scopus - 7Web of Science - 5
Co-authors Fred Menk
2012 King BW, Morf D, Greer PB, 'Development and testing of an improved dosimetry system using a backscatter shielded electronic portal imaging device', Medical Physics, 39 2839-2847 (2012) [C1]
Citations Scopus - 8Web of Science - 9
2012 Chandra SS, Dowling JA, Shen K-K, Raniga P, Pluim JPW, Greer PB, et al., 'Patient specific prostate segmentation in 3-D magnetic resonance images', IEEE Transactions on Medical Imaging, 31 1955-1964 (2012) [C1]
Citations Scopus - 32Web of Science - 29
2012 Rowshan Farzad P, Sabet M, O'Connor JD, Greer PB, 'Improvement of Varian a-Si EPID dosimetry measurements using a lead-shielded support-arm', Medical Dosimetry, 37 145-151 (2012) [C1]
Citations Scopus - 3Web of Science - 3
Co-authors John Oconnor
2012 Rowshan Farzad P, Sabet M, O'Connor JD, Greer PB, 'Impact of backscattered radiation from the bunker structure on EPID dosimetry', Journal of Applied Clinical Medical Physics, 13 91-100 (2012) [C1]
Citations Scopus - 1Web of Science - 1
Co-authors John Oconnor
2012 Rowshan Farzad P, Sabet M, O'Connor JD, McCowan PM, McCurdy BMC, Greer PB, 'Gantry angle determination during arc IMRT: evaluation of a simple EPID-based technique and two commercial inclinometers', Journal of Applied Clinical Medical Physics, 13 203-214 (2012) [C1]
Citations Scopus - 12Web of Science - 7
Co-authors John Oconnor
2012 Rowshan Farzad P, Sabet M, O'Connor JD, McCowan PM, McCurdy BMC, Greer PB, 'Detection and correction for EPID and gantry sag during arc delivery using cine EPID imaging', Medical Physics, 39 623-635 (2012) [C1]
Citations Scopus - 28Web of Science - 27
Co-authors John Oconnor
2012 Rowshan Farzad P, Sabet M, Barnes MP, O'Connor JD, Greer PB, 'EPID-based verification of the MLC performance for dynamic IMRT and VMAT', Medical Physics, 39 6192-6207 (2012) [C1]
DOI 10.1118/1.4752207
Citations Scopus - 19Web of Science - 17
Co-authors John Oconnor
2012 Dowling JA, Lambert JA, Parker J, Salvado O, Fripp J, Capp A, et al., 'An atlas-based electron density mapping method for Magnetic Resonance Imaging (MRI)-Alone treatment planning and adaptive MRI-Based prostate radiation therapy', International Journal of Radiation Oncology Biology Physics, 83 E5-E11 (2012) [C1]
Citations Scopus - 73Web of Science - 59
Co-authors Jim Denham
2011 Rowshan Farzad P, Sabet M, O'Connor JD, Greer PB, 'Isocenter verification for linac-based stereotactic radiation therapy: review of principles and techniques', Journal of Applied Clinical Medical Physics, 12 12 (2011) [C1]
Citations Scopus - 7Web of Science - 6
Co-authors John Oconnor
2011 Chandra S, Dowling J, Shen K, Pluim J, Greer PB, Salvado O, Fripp J, 'Automatic segmentation of the prostate in 3D magnetic resonance images using case specific deformable models', Proceedings: 2011 International Conference on Digital Image Computing: Techniques and Applications, DICTA 2011, 7-12 (2011) [E1]
DOI 10.1109/DICTA.2011.10
Citations Scopus - 3
2011 Greer PB, Dowling JA, Lambert JA, Fripp J, Parker J, Denham J, et al., 'A magnetic resonance imaging-based workflow for planning radiation therapy for prostate cancer', Medical Journal of Australia, 194 S24-S27 (2011) [C1]
Citations Scopus - 17Web of Science - 13
Co-authors Jim Denham
2011 Rowshan Farzad P, Sabet M, O'Connor JD, Greer PB, 'Verification of the linac isocenter for stereotactic radiosurgery using cine-EPID imaging and arc delivery', Medical Physics, 38 3963-3970 (2011) [C1]
DOI 10.1118/1.3597836
Citations Scopus - 22Web of Science - 19
Co-authors John Oconnor
2011 Gustafsson H, Vial P, Kuncic Z, Baldock C, Denham J, Greer PB, 'Direct dose to water dosimetry for pretreatment IMRT verification using a modified EPID', Medical Physics, 38 6257-6264 (2011) [C1]
DOI 10.1118/1.3656946
Citations Scopus - 5Web of Science - 4
Co-authors Jim Denham
2011 Hatton J, Greer PB, Tang C, Wright P, Capp A, Gupta S, et al., 'Does the planning dose-volume histogram represent treatment doses in image-guided prostate radiation therapy? Assessment with cone-beam computerised tomography scans', Radiotherapy and Oncology, 98 162-168 (2011) [C1]
DOI 10.1016/j.radonc.2011.01.006
Citations Scopus - 37Web of Science - 34
Co-authors Jim Denham, Joan Hatton
2011 Lambert JA, Greer PB, Menk FW, Patterson J, Parker J, Dahl K, et al., 'MRI-guided prostate radiation therapy planning: Investigation of dosimetric accuracy of MRI-based dose planning', Radiotherapy and Oncology, 98 330-334 (2011) [C1]
DOI 10.1016/j.radonc.2011.01.012
Citations Scopus - 48Web of Science - 37
Co-authors Jim Denham, Fred Menk
2011 King BW, Clews L, Greer PB, 'Long-term two-dimensional pixel stability of EPIDs used for regular linear accelerator quality assurance', Australasian Physical & Engineering Sciences in Medicine, 34 459-466 (2011) [C1]
Citations Scopus - 5Web of Science - 5
2010 Ansbacher W, Swift C-L, Greer PB, 'An evaluation of cine-mode 3D portal image dosimetry for volumetric modulated arc therapy', Journal of Physics: Conference Series, 012022 (2010) [E1]
DOI 10.1088/1742-6596/250/1/012022
Citations Scopus - 8
2010 Rowshan Farzad P, McCurdy BMC, Sabet M, Lee CG, O'Connor JD, Greer PB, 'Measurement and modeling of the effect of support arm backscatter on dosimetry with a Varian EPID', Medical Physics, 37 2269-2278 (2010) [C1]
DOI 10.1118/1.3369445
Citations Scopus - 35Web of Science - 32
Co-authors John Oconnor
2010 Sabet M, Menk FW, Greer PB, 'Evaluation of an a-Si EPID in direct detection configuration as a water-equivalent dosimeter for transit dosimetry', Medical Physics, 37 1459-1467 (2010) [C1]
DOI 10.1118/1.3327456
Citations Scopus - 19Web of Science - 16
Co-authors Fred Menk
2010 Rowshan Farzad P, Sabet M, O'Connor JD, Greer PB, 'Reduction of the effect of non-uniform backscatter from an E-type support arm of a Varian a-Si EPID used for dosimetry', Physics in Medicine and Biology, 55 6617-6632 (2010) [C1]
DOI 10.1088/0031-9155/55/22/003
Citations Scopus - 9Web of Science - 8
Co-authors John Oconnor
2009 Ebert MA, Kenny J, Greer PB, 'Experience converting an RT department to full CT simulation: Technical issues identified during commissioning of a wide-bore scanner', Journal of Medical Imaging and Radiation Oncology, 53 325-330 (2009) [C1]
DOI 10.1111/j.1440-1673.2009.02075.x
Citations Scopus - 2Web of Science - 2
2009 Hatton J, McCurdy B, Greer PB, 'Cone beam computerized tomography: The effect of calibration of the Hounsfield unit number to electron density on dose calculation accuracy for adaptive radiation therapy', Physics in Medicine and Biology, 54 N329-N346 (2009) [C1]
DOI 10.1088/0031-9155/54/15/n01
Citations Scopus - 60Web of Science - 48
Co-authors Joan Hatton
2009 Gardner JK, Clews L, Gordon JJ, Wang S, Greer PB, Siebers JV, 'Comparison of sources of exit fluence variation for IMRT', Physics in Medicine and Biology, 54 N451-N458 (2009) [C1]
DOI 10.1088/0031-9155/54/19/n03
Citations Scopus - 1
2009 Vial P, Gustafsson H, Oliver L, Baldock C, Greer PB, 'Direct-detection EPID dosimetry: Investigation of a potential clinical configuration for IMRT verification', Physics in Medicine and Biology, 54 7151-7169 (2009) [C1]
DOI 10.1088/0031-9155/54/23/008
Citations Scopus - 6Web of Science - 4
2009 McCurdy BMC, Greer PB, 'Dosimetric properties of an amorphous-silicon EPID used in continuous acquisition mode for application to dynamic and arc IMRT', Medical Physics, 36 3028-3039 (2009) [C1]
DOI 10.1118/1.3148822
Citations Scopus - 52Web of Science - 47
2009 Greer PB, Cadman P, Lee CG, Bzdusek K, 'An energy fluence-convolution model for amorphous silicon EPID dose prediction', Medical Physics, 36 547-555 (2009) [C1]
DOI 10.1118/1.3058481
Citations Scopus - 18Web of Science - 17
2009 Lee CG, Menk FW, Cadman P, Greer PB, 'A simple approach to using an amorphous silicon EPID to verify IMRT planar dose maps', Medical Physics, 36 984-992 (2009) [C1]
DOI 10.1118/1.3075817
Citations Scopus - 20Web of Science - 19
Co-authors Fred Menk
2009 Wang S, Gardner JK, Gordon JJ, Li W, Clews L, Greer PB, Siebers JV, 'Monte Carlo-based adaptive EPID dose kernel accounting for different field size responses of imagers', Medical Physics, 36 3582-3595 (2009) [C1]
DOI 10.1118/1.3158732
Citations Scopus - 14Web of Science - 12
2009 Clews L, Greer PB, 'An EPID based method for efficient and precise asymmetric jaw alignment quality assurance', Medical Physics, 36 5488-5496 (2009) [C1]
DOI 10.1118/1.3253463
Citations Scopus - 7Web of Science - 6
2009 Gustafsson H, Vial P, Kuncic Z, Baldock C, Greer PB, 'EPID dosimetry: Effect of different layers of materials on absorbed dose response', Medical Physics, 36 5665-5674 (2009) [C1]
DOI 10.1118/1.3245886
Citations Scopus - 10Web of Science - 10
2009 Haworth A, Kearvell R, Greer PB, Hooton B, Denham J, Lamb D, et al., 'Assuring high quality treatment delivery in clinical trials: Results from the Trans-Tasman Radiation Oncology Group (TROG) study 03.04 'RADAR' set-up accuracy study', Radiotherapy and Oncology, 90 299-306 (2009) [C1]
DOI 10.1016/j.radonc.2008.10.011
Citations Scopus - 25Web of Science - 22
Co-authors Jim Denham
2009 Denham J, Kumar M, Gleeson PS, Lamb DS, Joseph D, Atkinson C, et al., 'Recognizing false biochemical failure calls after radiation with or without neo-adjuvant androgen deprivation for prostate cancer', International Journal of Radiation Oncology Biology Physics, 74 404-411 (2009) [C1]
DOI 10.1016/j.ijrobp.2008.08.047
Citations Scopus - 9Web of Science - 7
Co-authors Catherine Deste, Jim Denham, Allison Steigler
2009 Denham J, Steigler A, Kumar M, Lamb DS, Joseph D, Spry NA, et al., 'Measuring time to biochemical failure in the Trog 96.01 trial: When should the clock start ticking?', International Journal of Radiation Oncology Biology Physics, 75 1008-1012 (2009) [C1]
DOI 10.1016/j.ijrobp.2008.12.085
Citations Scopus - 7Web of Science - 5
Co-authors Allison Steigler, Jim Denham, Catherine Deste
2008 Denham J, Steigler A, Wilcox C, Lamb DS, Joseph D, Atkinson C, et al., 'Time to biochemical failure and prostate-specific antigen doubling time as surrogates for prostate cancer-specific mortality: evidence from the TROG 96.01 randomised controlled trial', Lancet Oncology, 9 1058-1068 (2008) [C1]
DOI 10.1016/s1470-2045(08)70236-5
Citations Scopus - 52Web of Science - 43
Co-authors Catherine Deste, Jim Denham, Allison Steigler
2008 Greer PB, Dahl K, Ebert MA, White M, Wratten C, Ostwald PM, et al., 'Assessment of a daily online implanted fiducial marker-guided prostate radiotherapy process', Journal of Medical Imaging and Radiation Oncology, 52 517-524 (2008) [C1]
DOI 10.1111/j.1440-1673.2008.02006.x
Citations Scopus - 5Web of Science - 4
Co-authors Jim Denham, Patricia Ostwald
2008 Greer PB, Dahl K, Ebert MA, Wratten C, White M, Denham J, 'Comparison of prostate set-up accuracy and margins with off-line bony anatomy corrections and online implanted fiducial-based corrections', Journal of Medical Imaging and Radiation Oncology, 52 511-516 (2008) [C1]
DOI 10.1111/j.1440-1673.2008.02005.x
Citations Scopus - 20Web of Science - 18
Co-authors Jim Denham
2008 Vial P, Greer PB, Hunt P, Oliver L, Baldock C, 'The impact of MLC transmitted radiation on EPID dosimetry for dynamic MLC beams', Medical Physics, 35 1267-1277 (2008) [C1]
DOI 10.1118/1.2885368
Citations Scopus - 28Web of Science - 29
2008 Vial P, Greer PB, Oliver L, Baldock C, 'Initial evaluation of a commercial EPID modified to a novel direct-detection configuration for radiotherapy dosimetry', Medical Physics, 35 4362-4374 (2008) [C1]
DOI 10.1118/1.2975156
Citations Scopus - 19Web of Science - 17
2008 Vial P, Hunt P, Greer PB, Oliver L, Baldock C, 'Software tool for portal dosimetry research', Australasian Physical & Engineering Sciences in Medicine, 31 216-222 (2008) [C1]
DOI 10.1007/BF03179347
Citations Scopus - 2Web of Science - 2
2008 Ebert MA, Lambert JA, Greer PB, 'CT-ED conversion on a GE Lightspeed-RT scanner: Influence of scanner settings', Australasian Physical and Engineering Sciences in Medicine, 31 154-159 (2008) [C1]
DOI 10.1007/BF03178591
Citations Scopus - 5Web of Science - 4
2007 Greer PB, Barnes MP, 'Investigation of an amorphous silicon EPID for measurement and quality assurance of enhanced dynamic wedge', Physics in Medicine and Biology, 52 1075-1087 (2007) [C1]
DOI 10.1088/0031-9155/52/4/014
Citations Scopus - 18Web of Science - 18
2007 Greer PB, 'Off-axis dose response characteristics of an amorphous silicon electronic portal imaging device', Medical Physics, 34 3815-3824 (2007) [C1]
DOI 10.1118/1.2779944
Citations Scopus - 26Web of Science - 28
2007 Greer PB, Vial P, Oliver L, Baldock C, 'Experimental investigation of the response of an amorphous silicon EPID to intensity modulated radiotherapy beams', Medical Physics, 34 4389-4398 (2007) [C1]
DOI 10.1118/1.2789406
Citations Scopus - 32Web of Science - 30
2006 Vial P, Oliver L, Greer PB, Baldock C, 'An experimental investigation into the radiation field offset of a dynamic multileaf collimator', Physics in Medicine and Biology, 51 5517-5538 (2006) [C1]
DOI 10.1088/0031-9155/51/21/009
Citations Scopus - 16Web of Science - 15
2005 Greer PB, 'Correction of pixel sensitivity variation and off-axis response for amorphous silicon EPID dosimetry', Medical Physics, 32 3558-3578 (2005) [C1]
DOI 10.1118/1.2128498
Citations Scopus - 70Web of Science - 69
2005 Ludbrook JJS, Greer PB, Blood P, D'Yachkova Y, Coldman A, Beckham WA, et al., 'Correction Of Systematic Setup Errors in Prostate Radiation Therapy: How Many Images to Perform?', Medical Dosimetry, 30 76-84 (2005) [C1]
DOI 10.1016/j.meddos.2005.03.003
Citations Scopus - 15Web of Science - 14
2003 Greer PB, Beckham WA, 'Improving the resolution of intensity modulated delivery by reducing the MLC leaf sampling distance', Medical Physics, 30 2793-2801 (2003) [C1]
DOI 10.1118/1.1609992
Citations Scopus - 1Web of Science - 2
2003 Greer PB, Popescue CC, 'Dosimetric properties of an amorphous silicon electronic portal imaging device for verification of dynamic intensity modulated radiation therapy', Medical Physics, 30 1618-1627 (2003) [C1]
DOI 10.1118/1.1582469
Citations Scopus - 157Web of Science - 140
2003 Greer PB, Beckham WA, 'The effect of leaf width and sampling distance on the ''stair-stepping'' of field borders defined by multileaf collimators', Australasian Physical and Engineering Sciences in Medicine, 26 44-51 (2003) [C1]
DOI 10.1007/BF03178457
Citations Scopus - 2
2002 Popescu C, Greer P, Wells D, 'Use of an amorphous silicon electronic portal imaging device for dynamic multileaf collimator quality assurance', MEDICAL PHYSICS, 29 1366-1366 (2002)
Citations Web of Science - 1
2000 Greer PB, van Doorn T, 'Evaluation of an algorithm for the assessment of the MTF using an edge method', MEDICAL PHYSICS, 27 2048-2059 (2000)
DOI 10.1118/1.1288682
Citations Scopus - 73Web of Science - 61
2000 Greer PB, van Doom T, 'A design for a dual assembly multileaf collimator', MEDICAL PHYSICS, 27 2242-2255 (2000)
DOI 10.1118/1.1290731
Citations Scopus - 2Web of Science - 2
1998 Greer PB, Jose CC, Matthews JHL, 'Set-up variation of patients treated with radiotherapy to the prostate measured with an electronic portal imaging device', Australasian Radiology, 42 207-212 (1998)

The set-up variation of 11 patients treated supine with radical radiotherapy for carcinoma of the prostate was measured with an electronic portal imaging device to determine the a... [more]

The set-up variation of 11 patients treated supine with radical radiotherapy for carcinoma of the prostate was measured with an electronic portal imaging device to determine the adequacy of set-up techniques and current margins, as well as the need for immobilization. During the treatments 172 images of the anterior fields and 159 images of the left- lateral fields were taken and the errors in treatment placement were measured by template matching. The variation in the superior-inferior direction was small, 1.4-1.6 mm (1 SD), while the medio-lateral variation was 2.8 mm (1 SD). The anterior-posterior variation was largest, 4.6 mm (1 SD) with an offset of 3.3 mm anterior. This anterior offset and large anterior-posterior variation suggests that set-up techniques were not optimal for this direction. The 1 cm margin used was adequate for set-up variation except in a small number of cases, which was mainly due to the anterior trend. Random (treatment-to-treatment) variations were small (1.1-2.3 mm; 1 SD), indicating that immobilization would result in only modest improvement in reproducibility for these supine patients.

Citations Scopus - 14
1998 Greer PB, Mortensen TM, Rad DT, Jose CC, 'Comparison of two methods for anterior-posterior isocenter localization in pelvic radiotherapy using electronic portal imaging', INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 41 1193-1199 (1998)
DOI 10.1016/S0360-3016(98)00160-6
Citations Scopus - 30Web of Science - 21
1997 Greer PB, Mortensen TM, 'Anterior-posterior treatment localization in pelvic radiotherapy: Tattoos or fixed couch-to-isocentre distance', Medical Dosimetry, 22 43-46 (1997)

The methods of determining the anterior-posterior isocentre location in pelvic radiotherapy are either by aligning lateral localization lasers to tattoo marks on skin, or by setti... [more]

The methods of determining the anterior-posterior isocentre location in pelvic radiotherapy are either by aligning lateral localization lasers to tattoo marks on skin, or by setting a constant daily couch-to-isocentre distance. While using the former method the day-to-day vertical couch movement was recorded and combined with measurements of day-to-day anterior- posterior patient movement made with an electronic portal imaging device to determine whether couch vertical movement contributes to anterior-posterior setup variation. Seven unimmobilized patients were studied, four supine prostate and three prone rectum patients. The two motions were found to be highly correlated (correlation coefficient = 0.82) which supports the constant couch-to-isocentre distance approach. When the day-to-day couch vertical movement was subtracted from the anterior-posterior movement results the setup variation was reduced in six of the seven patients.

DOI 10.1016/S0958-3947(96)00156-2
Citations Scopus - 4
1996 Greer PB, 'Image timing and detector performance of a matrix ion-chamber electronic portal imaging device', Australasian Physical and Engineering Sciences in Medicine, 19 264-269 (1996)

Image timing and input/output characteristics of a Varian PortalVision¿ matrix liquid ion-chamber electronic portal imaging device (EPID) used with a Varian CL2100C/D linear acce... [more]

Image timing and input/output characteristics of a Varian PortalVision¿ matrix liquid ion-chamber electronic portal imaging device (EPID) used with a Varian CL2100C/D linear accelerator were investigated to examine the variation in image timing and detector performance with acquisition mode. Contrast-detail curves showed that the input/output results were indicative of the image quality variation with acquisition mode. Overall for this accelerator/EPID arrangement the 500 MU/min repetition rate gives the best image quality for the 6 MV and 18 MV acquisition modes.

Citations Scopus - 1
1994 Hodgkinson IJ, Greer PB, Molteno AC, 'Point-spread function for light scattered in the human ocular fundus.', Journal of the Optical Society of America. A, Optics, image science, and vision, 11 479-486 (1994)
1993 Greer PB, Molteno ACB, Hodgkinson IJ, 'Reflected line spread function of the human ocular fundus', Australasian Physical and Engineering Sciences in Medicine, 16 168-173 (1993)
Show 105 more journal articles

Review (1 outputs)

Year Citation Altmetrics Link
2013 Greer PB, '3D EPID based dosimetry for pre-treatment verification of VMAT - methods and challenges', Journal of Physics: Conference Series (2013) [E1]
DOI 10.1088/1742-6596/444/1/012010
Citations Scopus - 4Web of Science - 2

Conference (77 outputs)

Year Citation Altmetrics Link
2015 Lee D, Greer P, Lapuz C, Ludbrook J, Pollock S, Kim T, Keall P, 'Audiovisual Biofeedback Improves Breath-Hold Lung Tumor Position Reproducibility Measured with 4D MRI', Medical Physics (2015) [E3]
DOI 10.1118/1.4924322
2015 Lee D, Greer P, Ludbrook J, Paganelli C, Pollock S, Kim T, Keall P, 'Audiovisual Biofeedback Improves the Correlation Between Internal and External Respiratory Motion', MEDICAL PHYSICS (2015) [E3]
2015 Miri N, Baltes C, Keller P, Greer P, 'Development of Dose-To-Water Conversion Models for Pre-Treatment Verification with the New AS1200 Imager', MEDICAL PHYSICS (2015) [E3]
2015 Lehmann J, Miri N, Vial P, Hatton J, Zwan B, Craig A, et al., 'Remote Dosimetric Credentialing for Clinical Trials with the Virtual EPID Standard Phantom Audit (VESPA)', MEDICAL PHYSICS (2015) [E3]
Citations Web of Science - 1
Co-authors Joan Hatton
2015 Paganelli C, Lee D, Kipritidis J, Greer P, Riboldi M, Keall P, '3D Reconstruction From 2D CineMRI Orthogonal Slices: A Feasibility Study', MEDICAL PHYSICS (2015) [E3]
2015 Lehmann J, Bhatia S, Walsh S, Field M, Barakat M, Greer P, et al., 'SIFTING DATA FROM THE CLINICAL COALFACE: DATAMINING IN RADIATION ONCOLOGY TO AID CLINICAL DECISIONS', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY (2015) [E3]
2015 Miri N, Lehmann J, Greer P, 'EPID DOSIMETRY FOR CREDENTIALING IMRT TREATMENTS OF DIFFERENT CENTRES', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY (2015) [E3]
2015 Fuangrod T, Greer P, Middleton R, 'DEVELOPMENT OF ACTION LIMITS FOR PATIENT ERROR DETECTION FOR AN EPID-BASED REAL-TIME DELIVERY VERIFICATION SYSTEM', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY (2015) [E3]
Co-authors Richard Middleton
2015 Panicker N, Watt L, Kahl R, Dun M, Greer P, Skelding K, Verrills N, 'REDUCED EXPRESSION OF PROTEIN PHOSPHATASE 2A SUBUNIT, B55A, IN BREAST CANCER DNA DAMAGE REPAIR PATHWAYS', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY (2015) [E3]
Co-authors Nikki Verrills, Kathryn Skelding, Matt Dun
2014 Rivest-Hénault D, Ghose S, Pluim JPW, Greer PB, Fripp J, Dowling JA, 'Fast multiatlas selection using composition of transformations for radiation therapy planning', Medical Computer Vision: Algorithms for Big Data. International Workshop, MCV 2014 Held in Conjunction with MICCAI 2014 Cambridge, MA, USA, September 18, 2014 Revised Selected Papers (2014) [E1]
DOI 10.1007/978-3-319-13972-2_10
Citations Web of Science - 2
2013 Vial P, Blake SJ, McNamara AL, Holloway L, Greer PB, Kuncic Z, 'A new concept in detector design for radiation therapy: Simultaneous imaging and dosimetry for comprehensive treatment verification', IEEE Nuclear Science Symposium Conference Record (2013)

Radiation therapy treatment verification is currently limited to image-guided radiotherapy to verify patient and target location. There is no widely available method for direct ve... [more]

Radiation therapy treatment verification is currently limited to image-guided radiotherapy to verify patient and target location. There is no widely available method for direct verification of the delivered dose. Imaging has been widely implemented with amorphous silicon (a-Si) flat panel imagers. a- Si imagers can also be used to verify dose delivered to the patient, but current detector designs are problematic for dosimetry. Our group is investigating new detector designs optimized for simultaneous imaging and dosimetry. Detector specifications for megavoltage radiographic imaging and radiation dosimetry are in some respects contradictory to each other, presenting a significant technical challenge for detector design. The first generation of our prototype detectors consist of plastic scintillator fiber arrays interfaced directly onto a-Si imagers. Experimental and modeling studies are being conducted to optimize this design and determine the feasibility. Results to-date demonstrate excellent dosimetry and promising imaging performance, with significant potential for improvement. Ongoing detector developments are focused on improving detective quantum efficiency for imaging performance. We have demonstrated the feasibility of the plastic scintillator based detector and continue to optimize the design to develop a detector for comprehensive radiation therapy treatment verification. © 2013 IEEE.

DOI 10.1109/NSSMIC.2013.6829051
2013 Sun J, Dowling J, Menk F, Stanwell P, Salvado O, Parker J, Greer P, 'Investigation on CIVCO coil mount for MR-based prostate treatment planning', Australasian Physical & Engineering Sciences in Medicine (2013) [E3]
DOI 10.1007/s13246-012-0168-7
Co-authors Fred Menk, Peter Stanwell
2013 Greer P, Fuangrod T, Woodruff H, Rowshanfarzad P, van Uytven E, McCurdy B, 'Real-Time EPID-Based Dose Verification System for Detection of Gross Radiation Treatment Delivery Errors', INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2013)
2012 Fuangrod T, Woodruff H, Vanuytven E, McCurdy B, O'Connor JD, Greer PB, 'Simulations of real-time geometric and dosimetic verification system using EPID', Medical Physics (2012) [E3]
Citations Web of Science - 1
Co-authors John Oconnor
2012 Blake S, Vial P, Holloway L, McNamara A, Greer PB, Kuncic Z, 'Sensitivity analysis of an electronic portal imaging device Monte Carlo model to variations in optical transport parameters', Medical Physics (2012) [E3]
2012 King BW, Greer PB, 'A method to remove support arm backscatter from EPID images', Medical Physics (2012) [E3]
2012 Vial P, Deshpande S, Blake S, McNamara A, Holloway L, Greer PB, Kuncic Z, 'First experiments of a prototype device for simultaneous imaging and dose verification in radiotherapy', Medical Physics (2012) [E3]
Citations Web of Science - 2
2012 Whelan B, Kumar S, Dowling J, Lambert JA, Lim K, Salvado O, et al., 'Requirements for the accuracy of electron density data planning for MRI based cervix cancer treatment planning', Medical Physics (2012) [E3]
2011 Fuangrod T, O'Connor JD, McCurdy BMC, Greer PB, 'Development of EPID-based real time dose verification for dynamic IMRT', Proceedings of World Academy of Science, Engineering and Technology (2011) [E1]
Citations Scopus - 3
Co-authors John Oconnor
2011 Greer PB, Vial P, 'Epid dosimetry', Concepts and Trends in Medical Radiation Dosimetry: Proceedings of the SSD Summer School (2011) [E1]
DOI 10.1063/1.3576163
Citations Scopus - 4Web of Science - 4
2011 Dowling JA, Fripp J, Chandra S, Pluim JPW, Lambert JA, Parker J, et al., 'Fast automatic multi-atlas segmentation of the prostate from 3D MR images', International Workshop on Prostate Cancer Imaging: Image Analysis and Image-Guided Interventions Proceedings (LNCS 6963) (2011) [E1]
DOI 10.1007/978-3-642-23944-1_2
Citations Scopus - 21Web of Science - 19
Co-authors Jim Denham
2011 Rowshan Farzad P, Sabet M, McCowan P, McCurdy B, O'Connor D, Greer PB, 'MO-F-214-08: A New Method for Linear Accelerator Characterization for VMAT Using Cine-EPID', Medical Physics (2011) [C3]
DOI 10.1118/1.3613021
Co-authors John Oconnor
2011 Rowshan Farzad P, Sabet M, McCowan P, McCurdy B, O'Connor JD, Greer PB, 'A new method for linear accelerator characterization for VMAT using Cine-EPID', Medical Physics (2011) [E3]
Co-authors John Oconnor
2011 Blake S, Vial P, Holloway L, Greer PB, Kuncic Z, 'An investigation into optical photon transport effects on electronic portal imaging performance using Geant4', Medical Physics (2011) [E3]
2011 King BR, Morf D, Greer PB, 'Investigation of a modified backscatter-shielded EPID dosimetry system for improved IMRT verification', Medical Physics (2011) [E3]
2011 Lambert JA, Dowling J, Menk FW, Parker J, Capp A, Denham J, et al., 'MR-based dose calculation for prostate radiotherapy using atlas-based auto-segmentation', Medical Physics (2011) [E3]
Co-authors Fred Menk, Jim Denham
2011 McCowan P, Rickey D, Rowshan Farzad P, Ansbacher W, Greer PB, McCurdy B, 'Precise gantry angle determination for EPID images during rotational IMRT', Medical Physics (2011) [E3]
2010 Vial P, Kunic Z, Gustafsson H, Oliver L, Sabet M, Baldock C, Greer PB, 'Developing a next generation detector for radiotherapy treatment verification', Sydney Cancer Conference 2010. Profiling Risk, Personalising Treatment and Predicting Outcomes. Conference Program and Abstract Book (2010) [E3]
2010 Dowling J, Lambert JA, Parker J, Greer PB, Fripp J, Denham J, et al., 'Automatic MRI atlas-based external beam radiation therapy treatment planning for prostate cancer', Prostate Cancer Imaging: Computer-Aided Diagnosis, Prognosis, and Intervention International Workshop, Held in Conjunction with MICCAI 2010, Beijing,China, September 24, 2010. Proceedings (2010) [E1]
Citations Scopus - 10Web of Science - 10
Co-authors Jim Denham
2009 Hatton J, Capp A, Gupta S, Tang C, Wright P, Greer PB, 'Assessment of dose delivered during prostate radiotherapy using cone beam CT scans for adaptive radiotherapy', Journal of Medical Imaging and Radiation Oncology (2009) [E3]
Co-authors Joan Hatton
2009 Gustafsson H, Vial P, Kuncic Z, Baldock C, Denham J, Greer PB, 'Intensity modulated radiation therapy verification with a novel modified EPID design', Journal of Medical Imaging and Radiation Oncology (2009) [E3]
Co-authors Jim Denham
2009 Rowshan Farzad P, Sabet M, McCurdy BMC, O'Connor JD, Greer PB, 'A measurement-based model for backscatter from an a-Si EPID support arm to improve IMRT dose verification', Journal of Medical Imaging and Radiation Oncology (2009) [E3]
Co-authors John Oconnor
2009 Dowling J, Neubert A, Fripp J, Bourgeat P, Patterson J, Denham J, et al., 'Atlas-based, automatic segmentation of the pelvis for prostate radiotherapy planning', Journal of Medical Imaging and Radiation Oncology (2009) [E3]
DOI 10.1111/j.1440-1673.2009.01207.x
Co-authors Jim Denham
2009 Sabet M, Menk FW, Greer PB, 'Evaluation of a modified amorphous silicon electronic portal imaging device for transit dosimetry', Journal of Medical Imaging and Radiation Oncology (2009) [E3]
DOI 10.1111/j.1440-1673.2009.01207.x
Co-authors Fred Menk
2009 Sabet M, Menk FW, Greer PB, 'Investigation of the effect of dose rate variations on response of an a-Si EPID in clinical and modified configurations', Journal of Medical Imaging and Radiation Oncology (2009) [E3]
DOI 10.1111/j.1440-1673.2009.01211.x
Co-authors Fred Menk
2009 Dowling J, Bourgeat P, Raffelt D, Fripp J, Greer PB, Patterson J, et al., 'Non-rigid correction of interleaving artefacts in pelvic MRI', Medical Imaging 2009: Image Processing (2009) [E1]
DOI 10.1117/12.812460
Citations Scopus - 3
Co-authors Jim Denham, Peter Stanwell
2009 McCurdy BMC, Greer PB, 'Dosimetric properties of an EPID for real-time dose verification', Medical Physics (2009) [E3]
2008 Lee CG, Greer PB, Menk FW, 'The effect of non-uniform backscatter on EPID dosimetry', EPSM ABEC 2008: Innovations in Patient Care: Conference Handbook (2008) [E3]
Co-authors Fred Menk
2008 Lambert JA, Greer PB, Patterson J, Dowling J, Salvado O, Menk FW, 'Bulk electron density treatment planning for MRI-based prostate radiotherapy', EPSM ABEC 2008: Innovations in Patient Care: Conference Handbook (2008) [E3]
Co-authors Fred Menk
2008 Vial P, Greer PB, Lee CG, Gustafsson H, Oliver L, Baldock C, 'Contributing factors in the field size response of an EPID', EPSM ABEC 2008: Innovations in Patient Care: Conference Handbook (2008) [E3]
2008 Hatton J, Greer PB, 'Evaluation of cone beam CT data for dose calculation in adaptive planning', EPSM ABEC 2008: Innovations in Patient Care: Conference Handbook (2008) [E3]
Co-authors Joan Hatton
2008 Vial P, Hunt P, Greer P, Oliver L, Baldock C, 'Proceedings of Student Research Symposium of the ACT/NSW Branch of the Australasian College of Physical Scientists and Engineering in Medicine Friday 7 December 2007 Slade Lecture Theatre Institute of Medical Physics School of Physics University of Sydney', AUSTRALASIAN PHYSICAL & ENGINEERING SCIENCES IN MEDICINE (2008) [C1]
2007 Denham J, Joseph D, Lamb D, Tai KH, Turner S, Matthews J, et al., 'Reasons for initial PSA (iPSA) and biochemical failure (BF) being poor predictors of prostate cancer (PC) mortality', European Journal of Cancer Supplements (ECCO 14 Abstract Book) (2007) [E3]
DOI 10.1016/s1359-6349(07)71071-6
Co-authors Jim Denham, Allison Steigler
2007 Clews L, Greer PB, 'Linear accelerator quality assurance with an a-Si EPID', Australasian Physical and Engineering Sciences in Medicine (2007) [E3]
2007 Hatton J, Tehovnik T, Greer PB, 'Investigation of an objective comparison of measured and calculated profiles using dose and distance to agreement', Australasian Physical and Engineering Sciences in Medicine (2007) [E3]
2007 Greer PB, Cadman P, Bzdusek K, 'A Fluence-convolution model for prediction of amorphous silicon EPID IMRT images', Australasian Physical and Engineering Sciences in Medicine (2007) [E3]
2007 Tehovnik T, Greer PB, Carolan M, Ansbacher W, Metcalfe P, 'Three dimensional dose verification for IMRT using amorphous silicon EPIDS', Australasian Physical and Engineering Sciences in Medicine (2007) [E3]
2007 Vial P, Hunt P, Greer PB, Oliver L, Baldock C, 'A comparison of portal dosimetry and dose to water measurements of IMRT beams', Australasian Physical and Engineering Sciences in Medicine (2007) [E3]
2007 Ebert MA, Lambert JA, Greer PB, 'CT-number dependence on KV/MA settings - Influence of auto-mA', EPSM-ABEC 2007. Australasian Physical and Engineering Sciences in Medicine. Proceedings (2007) [E3]
2007 Popescu C, Greer P, 'Eclipse AAA versus pinnacle dose prediction for transit dosimetry: Comparison with Monte Carlo', RADIOTHERAPY AND ONCOLOGY (2007)
2007 Greer PB, Clews L, 'Comprehensive linear accelerator quality assurance with an A-SI EPID', Radiotherapy & Oncology (2007) [E3]
2007 Popescu C, Greer PB, 'Eclipse AAA Vs Pinnacle dose prediction for transit dosimetry: Comparison with Monte Carlo', Radiotherapy & Oncology (2007) [E3]
2007 Lee C, Greer PB, Cadman P, 'A simple approach to using the AS500 amorphous silicon EPID to verify IMRT fields', Radiotherapy & Oncology (2007) [E3]
2006 Greer PB, Dahl K, Ostwald PM, Denham J, Lau P, Hughes C, White M, 'An investigation of MRI dose planning for high precision prostate radiotherapy', Australasian Physical & Engineering Sciences in Medicine (2006) [E3]
Co-authors Patricia Ostwald, Jim Denham
2006 Greer PB, Dahl K, Ostwald PM, Pichler P, Denham J, Wratten C, White M, 'Initial clinical experience with implanted fiducial guided prostate radiotherapy', Australasian Physical & Engineering Sciences in Medicine (2006) [E3]
Co-authors Patricia Ostwald, Jim Denham
2006 Lee CG, Greer PB, Menk FW, 'Determination of optimal depth in water for comparison of planning system dose maps and EPID images', Australasian Physical & Engineering Sciences in Medicine (2006) [E3]
Co-authors Fred Menk
2006 Joseph D, Lamb D, Denham J, Tai K-H, Turner S, Matthews J, et al., 'The biological significance of longitudinal changes in PSA; Post treatment variation sand mistaken biochemical failure.', RADIOTHERAPY AND ONCOLOGY (2006)
Co-authors Jim Denham, Allison Steigler
2006 Denham J, Joseph D, Lamb D, Tai K-H, Turner S, Matthews J, et al., 'The biological significance of longitudinal changes in PSA; Doubling time during biochemical failure', RADIOTHERAPY AND ONCOLOGY (2006)
Co-authors Jim Denham, Allison Steigler
2006 Haworth A, Joseph D, Lamb D, Duchesne G, Kearvell R, Hooton B, et al., 'Quality control studies for radiation delivery in a multicentre prostate cancer clinical trial', RADIOTHERAPY AND ONCOLOGY (2006)
Co-authors Jim Denham
2006 Lamb D, Denham J, Joseph D, Tai K, Turner S, Matthews J, et al., 'The biological significance of longitudinal changes in PSA; Post treatment variations and mistaken biochemical failure', INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2006)
DOI 10.1016/j.ijrobp.2006.07.632
Co-authors Jim Denham, Allison Steigler
2006 Denham J, Joseph D, Lamb D, Tai K, Turner S, Matthews J, et al., 'The biological significance of longitudinal changes in PSA; Doubling time during biochemical failure', Proceedings of the 48th Annual Meeting of the American Society for Therapeutic Radiology and Oncology, 48th Annual Meeting of the American Society for Therapeutic Radiology and Oncology (2006) [E3]
Co-authors Jim Denham, Allison Steigler
2006 Greer PB, 'Preliminary investigaton of the effect of a-Si EPID spectral response on IMRT dosimetry', EPI2K6: Programme and Abstracts (2006) [E3]
2006 Greer PB, Cadman P, Bzdusek K, Carolan M, 'A fluence-convolution model for prediction of dosimetric EPID images incorporating off-axis spectral response', EPI2K6: Programme and Abstracts (2006) [E3]
2006 Haworth A, Kearvell R, Price S, Greer PB, Baily M, Hooton B, et al., 'The radar set-up accuracy study', EPI2K6: Programme and Abstracts (2006) [E3]
Co-authors Jim Denham
2006 Kenny J, Greer PB, Ebert MA, 'Generation of low kV portal images from a linear accelerator with an aSi EPID and an external imaging target', EPI2K6: Programme and Abstracts (2006) [E3]
2005 Dempsey CL, Greer PB, 'Verification of step-and-shoot breast compensator IMRT fields with an amorphous silicon EPID', Radiotherapy & Oncology (2005) [E3]
Co-authors Claire Dempsey
2005 Greer PB, 'The off-axis response of an amorphous silicon electronic portal imaging device', Radiotherapy & Oncology (2005) [E3]
2005 Greer PB, Barnes M, 'The two-dimensional dosimetric stability of the aS500 amorphous silicon EPID for measurement of absolute dose and beam profiles', Radiotherapy & Oncology (2005) [E3]
2005 Greer PB, Barnes M, 'Assessment of the aS500 amorphous silicon EPID for measurement of enhanced dynamic wedge', Radiotherapy & Oncology (2005) [E3]
2005 Ebrahimpour H, Greer PB, Ebert MA, Ourselin S, Popescu D, 'Evaluation of Art and Feildkamp Algorithms for Megavoltage CT', EPSM 2005 Conference Handbook (2005) [E3]
2004 Greer PB, 'Prediction of transmitted portal dose for in-vivo dosimetry by a superposition-convolution planning system', Conference Handbook (2004) [E3]
2004 Greer PB, 'An investigation of dose and beam profile dosimetry with an amorphous silicon epid', Conference Handbook (2004) [E3]
2004 Greer PB, Kenny J, 'Implementation of virtual simulation with a side-bore multislice helical CT scanner', Conference Handbook (2004) [E3]
2004 Kenny J, Ebert MA, Greer PB, 'Generation of low KV X-ray portal images with mega-voltage electron beams', Conference Handbook (2004) [E3]
2004 Greer PB, 'Assessment of an amorphous silicon epid for quality assurance of enhanced dynamic wedge', Conference handbook (2004) [E3]
2004 Greer PB, 'On-line imaging during treatment', Program and Abstract Book (2004) [E3]
2003 Greer PB, Chaney J, Bremner L, Graham C, 'Comparison of Inter-Observer Variability in Portal Image Registration with Single and Double-Exposure Images', CD-Rom (2003) [E3]
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Grants and Funding

Summary

Number of grants 45
Total funding $14,231,023

Click on a grant title below to expand the full details for that specific grant.


20171 grants / $593,742

Improving patient safety in radiation therapy with the Watchdog real-time treatment delivery verification system$593,742

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Conjoint Professor Peter Greer, Professor Richard Middleton, Conjoint Associate Professor Jarad Martin, Dr Jeremy Booth, Dr Boyd McCurdy, Dale Lovelock, Dr Andrew Kneebone
Scheme Project Grant
Role Lead
Funding Start 2017
Funding Finish 2019
GNo G1600453
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

20163 grants / $1,134,197

Reducing the greatest uncertainty in radiotherapy$594,197

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team

Holloway L, Haworth A, Dowling J, Ebert MA, Jameson M, Kron T, Vinod S, Leong T, Greer PB, Creutzberg C

Scheme Project Grant
Role Investigator
Funding Start 2016
Funding Finish 2016
GNo
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON N

A multistage multi centre international randomised trial of Conventional care Or Radioablation (CORE)$435,000

Funding body: Cancer Australia

Funding body Cancer Australia
Project Team

Faroudi F, Khoo V, Pryor D, Foote M, Ball D, Graham P, Martin J, Greer PB, Millwood M,

Scheme Priority-driven Collaborative Cancer Research Scheme
Role Investigator
Funding Start 2016
Funding Finish 2016
GNo
Type Of Funding Aust Competitive - Non Commonwealth
Category 1NS
UON N

The accuracy and utility of Intra-fraction Motion Review (IMR) in clinical practice using the Truebeam STx$105,000

Funding body: Varian Medical Systems, Inc.

Funding body Varian Medical Systems, Inc.
Project Team

Simpson J, Greer PB, Lehmann J

Scheme Research Grant
Role Investigator
Funding Start 2016
Funding Finish 2016
GNo
Type Of Funding International - Competitive
Category 3IFA
UON N

20154 grants / $637,000

Improving cancer imaging and targeted radiotherapy using audiovisual biofeedback$588,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team

Keall P, Kay, J, O’Brien R, Kron T, Greer PB, Hebblewhite M, Sawant A

Scheme Development Grant
Role Investigator
Funding Start 2015
Funding Finish 2016
GNo
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON N

Radiotherapy treatment for prostate cancer - a change in practice based on direct evidence for targeting and toxicity effects using real outcomes data$24,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Associate Professor Martin Ebert, Dr Jason Dowling, Conjoint Professor Jim Denham, Professor David Joseph, Dr Sarah Gulliford, Professor David Dearnaley, Associate Professor Annette Haworth, Dr Lois Holloway, Professor Tomas Kron, Conjoint Professor Peter Greer
Scheme Project Grant
Role Investigator
Funding Start 2015
Funding Finish 2017
GNo G1401429
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

VESPA$15,000

Funding body: Calvary Mater Newcastle

Funding body Calvary Mater Newcastle
Project Team Conjoint Professor Peter Greer, Doctor John Holdsworth, Doctor Andrew Fleming, Dr Joerg Lehmann, Miss Narges Miri
Scheme Project Grant
Role Lead
Funding Start 2015
Funding Finish 2015
GNo G1500770
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

VESPA project$10,000

Funding body: TROG (Trans Tasman Radiation Oncology Group)

Funding body TROG (Trans Tasman Radiation Oncology Group)
Project Team Conjoint Professor Peter Greer, Doctor John Holdsworth, Doctor Andrew Fleming, Dr Joerg Lehmann
Scheme Research Grant
Role Lead
Funding Start 2015
Funding Finish 2015
GNo G1401525
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

20144 grants / $7,063,356

Hunter Cancer Research Alliance; HCRA$5,978,356

Funding body: Cancer Institute NSW

Funding body Cancer Institute NSW
Project Team Conjoint Professor Stephen Ackland, Professor Rodney Scott, Professor John Forbes, Laureate Professor Robert Sanson-Fisher, Professor Xu Dong Zhang, Conjoint Associate Professor Anthony Proietto, Conjoint Professor Peter Greer, Associate Professor Christine Paul
Scheme Translational Cancer Research Centre Grants
Role Investigator
Funding Start 2014
Funding Finish 2019
GNo G1301098
Type Of Funding Other Public Sector - State
Category 2OPS
UON Y

Renewing Intersects share of the national computing infrastructure$1,025,000

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team

Hawkes, Evatt R; Yu, Aibing B; Ferry, Michael; Lewis, Geraint F; Muller, Dietmar; Wilkins, Marc R; Radom

Scheme Linkage Projects
Role Investigator
Funding Start 2014
Funding Finish 2016
GNo
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON N

Renewing Intersect's share of the National Computational Infrastructure's peak facility$40,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Associate Professor Evatt Hawkes, Professor Marc Wilkins, Assoc. Prof Aibing Yu, Professor Michael Ferry, Dr Graham Ball, Professor Geraint Lewis, Professor Dietmar Muller, Professor Leo Radom, Professor Catherine Stampfl, Dr Jeffrey Reimers, Associate Professor Christopher Poulton, Associate Professor Michael Ford, Dr Adel Rahmani, Dr Matthew Arnold, Dr Kei-Wai Cheung, Professor Mark Johnson, Associate Professor Orsola De Marco, Associate Professor Frans Henskens, Conjoint Professor Bogdan Dlugogorski, Conjoint Professor Peter Greer, Dr Haibo Yu, Professor Willy Susilo, Professor Abdulkadir Sajeev, Associate Professor Cedric Gondro, Associate Professor Chunhui Yang, Dr Ming Zhao, Professor Graham King, Professor Terry Bossomaier, Professor Arthur Georges
Scheme Equipment Grant
Role Investigator
Funding Start 2014
Funding Finish 2014
GNo G1300203
Type Of Funding Internal
Category INTE
UON Y

Rapid learning from datamining routine clinical datasets in radiotherapy$20,000

Funding body: Hunter Cancer Research Alliance

Funding body Hunter Cancer Research Alliance
Project Team

Lehmann J, Thwaites D, Ludbrook J, Dekker A, Holloway L, Greer PB, Vinod S

Scheme Pilot
Role Investigator
Funding Start 2014
Funding Finish 2016
GNo
Type Of Funding Other Public Sector - Local
Category 2OPL
UON N

20134 grants / $431,634

Safety and Quality: IMRT Treatment Delivery Accuracy$216,307

Funding body: ROI (Radiation Oncology Institute) USA

Funding body ROI (Radiation Oncology Institute) USA
Project Team Conjoint Professor Peter Greer, Dr Jarad Martin, Professor Paul Keall, Dr Michael Lovelock, Dr Yoshiya Yamada, Dr Boyd McCurdy, Dr James Butler, Dr Jeffrey Siebers, Associate Professor Elisabeth Weiss
Scheme Research Grant
Role Lead
Funding Start 2013
Funding Finish 2014
GNo G1300205
Type Of Funding International - Competitive
Category 3IFA
UON Y

The Australian MRI-Linac Program: Improving cancer treatment through real-time image guided adaptive radiotherapy$145,181

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Professor Paul Keall, Professor Michael Barton, Professor Stuart Crozier, Conjoint Professor Peter Greer
Scheme Program Grant
Role Lead
Funding Start 2013
Funding Finish 2017
GNo G1200920
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Pre-treatment verification of VMAT and in-vivo verification of patient treatments$50,146

Funding body: Calvary Mater Newcastle

Funding body Calvary Mater Newcastle
Project Team Conjoint Professor Peter Greer, Dr Jarad Martin, Professor Paul Keall, Dr Michael Lovelock, Dr Yoshiya Yamada, Dr Boyd McCurdy, Dr James Butler, Dr Jeffrey Siebers, Associate Professor Elisabeth Weiss
Scheme Project Grant
Role Lead
Funding Start 2013
Funding Finish 2013
GNo G1300893
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

Real-time verification of dynamic radiotherapy$20,000

Funding body: Hunter Cancer Research Alliance

Funding body Hunter Cancer Research Alliance
Scheme Pilot
Role Lead
Funding Start 2013
Funding Finish 2016
GNo
Type Of Funding Other Public Sector - Local
Category 2OPL
UON N

20126 grants / $1,273,437

An adaptable and dedicated linear accelerator for medical radiation research$600,000

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team

Paul Keall

Scheme Linkage Infrastructure Equipment & Facilities (LIEF)
Role Investigator
Funding Start 2012
Funding Finish 2013
GNo
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON N

Development of high precision MRI based prostate cancer radiation therapy$300,000

Funding body: Prostate Cancer Foundation of Australia

Funding body Prostate Cancer Foundation of Australia
Project Team

Jason Dowling

Scheme Young Investigator Grant
Role Investigator
Funding Start 2012
Funding Finish 2013
GNo
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON N

Project EVA: an environmentally responsible facility for interdisciplinary supercomputing applications$263,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Pablo Moscato, Laureate Professor Jon Borwein, Conjoint Professor Keith Jones, Conjoint Professor Chris Levi, Professor Mark Parsons, Professor Michael Ostwald, Professor Hugh Craig, Conjoint Professor Peter Greer, Associate Professor Stephan Chalup, Associate Professor Regina Berretta
Scheme Equipment Grant
Role Investigator
Funding Start 2012
Funding Finish 2012
GNo G1100627
Type Of Funding Internal
Category INTE
UON Y

Optimising radiation therapy delivery for cancer patients using daily image guidance to maximize cure and reduce normal tissue side effects$67,877

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Doctor Farshad Foroudi, Dr Thomas Eade, Professor Tomas Kron, Dr David Ball, Conjoint Professor Peter Greer
Scheme Project Grant
Role Lead
Funding Start 2012
Funding Finish 2014
GNo G1200358
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Implementation of EPID imaging infrastructure for research and development$27,560

Funding body: Calvary Mater Newcastle

Funding body Calvary Mater Newcastle
Project Team Conjoint Professor Peter Greer
Scheme Project Grant
Role Lead
Funding Start 2012
Funding Finish 2013
GNo G1201179
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

An adaptable and dedicated linear accelerator for medical radiation research$15,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Paul Keall, Associate Professor Michael Jackson, Professor Anatoly Rozenfeld, Professor Michael Barton, Conjoint Professor Peter Greer, Dr Philip Vial, Professor Clive Baldock, Professor Peter Metcalfe, Professor David Thwaites, Dr Zdenka Kuncic, Dr Lois Holloway, Dr Stephen Bosi, Dr Enid Eslick, Mr Simon Downes
Scheme Equipment Grant
Role Lead
Funding Start 2012
Funding Finish 2012
GNo G1100816
Type Of Funding Internal
Category INTE
UON Y

20114 grants / $722,920

Does the initial treatment plan predict doses delivered to normal tissues during prostate radiation therapy$349,795

Funding body: Cancer Council NSW

Funding body Cancer Council NSW
Project Team Conjoint Professor Peter Greer, Dr Jason Dowling, Conjoint Professor Jim Denham, Dr Olivier Salvado
Scheme Research Program
Role Lead
Funding Start 2011
Funding Finish 2016
GNo G1000377
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

A next generation detector for radiotherapy treatment verification with dual capability for simultaneous imaging and dosimetry$336,125

Funding body: Cancer Council NSW

Funding body Cancer Council NSW
Project Team

Philip Vial

Scheme Project Grant
Role Investigator
Funding Start 2011
Funding Finish 2013
GNo
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON N

The Pierre and Marie Curie GPU computing servers$27,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Professor Pablo Moscato, Conjoint Professor Peter Greer, Associate Professor Regina Berretta, Dr CARLOS Riveros
Scheme Equipment Grant
Role Investigator
Funding Start 2011
Funding Finish 2011
GNo G1100032
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

PULSE Early Career Medical Researcher of the Year Award$10,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Conjoint Professor Peter Greer
Scheme PULSE Early Career Researcher of the Year Award
Role Lead
Funding Start 2011
Funding Finish 2011
GNo G1001047
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

20105 grants / $812,058

Real-time dose monitoring for patient safety in radiation therapy$360,000

Funding body: Cancer Council NSW

Funding body Cancer Council NSW
Project Team Conjoint Professor Peter Greer, Dr Boyd McCurdy, Dr Zdenka Kuncic, Professor Clive Baldock, Conjoint Professor Jim Denham
Scheme Research Grant
Role Lead
Funding Start 2010
Funding Finish 2012
GNo G0190320
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Making radiotherapy safer and more accurate: Developing detector technology for the next generation in treatment verification systems$198,000

Funding body: Cancer Institute NSW

Funding body Cancer Institute NSW
Project Team

Philip Vial

Scheme Research Equipment Grant
Role Investigator
Funding Start 2010
Funding Finish 2010
GNo
Type Of Funding Other Public Sector - State
Category 2OPS
UON N

Adaptive Radiotherapy Incorporating Patient Dosimetry Feedback$120,000

Funding body: Cancer Care Manitoba

Funding body Cancer Care Manitoba
Project Team

Boyd McCurdy

Scheme Cancer Care Manitoba Research Grant
Role Investigator
Funding Start 2010
Funding Finish 2011
GNo
Type Of Funding International - Non Competitive
Category 3IFB
UON N

Equipment to assess the accuracy of image-guided and advanced technology used in radiotherapy clinical trials$94,058

Funding body: Cancer Institute NSW

Funding body Cancer Institute NSW
Project Team

Peter Greer

Scheme Research Equipment Grant
Role Lead
Funding Start 2010
Funding Finish 2010
GNo
Type Of Funding Other Public Sector - State
Category 2OPS
UON N

Investigation of Magnetic Resonance Imaging for Prostate Radiation Therapy Planing (PHD Top-up)$40,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Conjoint Professor Peter Greer, Professor Fred Menk
Scheme Research Higher Degree Support Grant
Role Lead
Funding Start 2010
Funding Finish 2011
GNo G0900135
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

20093 grants / $779,816

Investigation of a new electronic portal imaging device for radiation therapy dose delivery$393,441

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Conjoint Professor Peter Greer, Professor Clive Baldock, Dr Zdenka Kuncic, Conjoint Professor Jim Denham
Scheme Project Grant
Role Lead
Funding Start 2009
Funding Finish 2011
GNo G0188893
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Improving patient outcomes of radiotherapy treatments$365,375

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team

A Fielding

Scheme Project Grant
Role Investigator
Funding Start 2009
Funding Finish 2011
GNo
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON N

An investigation of adaptive radiation therapy for improved prostate cancer treatment outcomes$21,000

Funding body: Calvary Mater Newcastle Hospital

Funding body Calvary Mater Newcastle Hospital
Project Team

Joan Hatton

Scheme Wig Week Research Grant
Role Investigator
Funding Start 2009
Funding Finish 2009
GNo
Type Of Funding Other Public Sector - Local
Category 2OPL
UON N

20082 grants / $91,531

An investigation of pre-treatment cone-beam CT and adaptive planning for improved prostate cancer radiotherapy$68,531

Funding body: Cancer Institute NSW

Funding body Cancer Institute NSW
Project Team

Joan Hatton

Scheme Career Development Fellowship
Role Investigator
Funding Start 2008
Funding Finish 2008
GNo
Type Of Funding Other Public Sector - State
Category 2OPS
UON N

Radiation therapy treatment planning research infrastructure$23,000

Funding body: Calvary Mater Newcastle Hospital

Funding body Calvary Mater Newcastle Hospital
Project Team

Peter Greer

Scheme Coalfields and Wig Week Grant
Role Lead
Funding Start 2008
Funding Finish 2008
GNo
Type Of Funding Other Public Sector - Local
Category 2OPL
UON N

20075 grants / $504,878

High precision MRI based prostate radiotherapy$301,750

Funding body: Cancer Council NSW

Funding body Cancer Council NSW
Project Team Conjoint Professor Peter Greer, Conjoint Professor Jim Denham, Dr Sebastien Ourselin, Dr Martin Ebert, Doctor Trish Ostwald, Dr Peter Lau
Scheme Research Grant
Role Lead
Funding Start 2007
Funding Finish 2009
GNo G0186637
Type Of Funding Donation - Aust Non Government
Category 3AFD
UON Y

Improving the Verification of Intensity Modulated Radiation Therapy Dose Delivery with Flat-Panel Imagers$139,500

Funding body: Cancer Council NSW

Funding body Cancer Council NSW
Project Team Conjoint Professor Peter Greer, Dr Martin Ebert, Mr Patrick Cadman, Professor Clive Baldock, Conjoint Professor Jim Denham
Scheme Research Grant
Role Lead
Funding Start 2007
Funding Finish 2008
GNo G0186639
Type Of Funding Donation - Aust Non Government
Category 3AFD
UON Y

On-line verification of patient dose delivery in radiotherapy$25,000

Funding body: Calvary Mater Newcastle Hospital

Funding body Calvary Mater Newcastle Hospital
Project Team

Peter Greer

Scheme Wig Week Research Grant
Role Lead
Funding Start 2007
Funding Finish 2007
GNo
Type Of Funding Other Public Sector - Local
Category 2OPL
UON N

Improving the verification of intensity modulated radiation therapy with flat panel imagers$23,196

Funding body: Calvary Mater Newcastle

Funding body Calvary Mater Newcastle
Project Team Conjoint Professor Peter Greer, Professor Clive Baldock, Conjoint Professor Jim Denham
Scheme Project Grant
Role Lead
Funding Start 2007
Funding Finish 2008
GNo G0188380
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

Medical modelling computing grid$15,432

Funding body: Calvary Mater Newcastle Hospital

Funding body Calvary Mater Newcastle Hospital
Project Team

Peter Greer

Scheme Coalfields Equipment
Role Lead
Funding Start 2007
Funding Finish 2007
GNo
Type Of Funding Other Public Sector - Local
Category 2OPL
UON N

20052 grants / $111,454

NSW centre for research into quality of radiation therapy delivery$102,454

Funding body: Cancer Institute NSW

Funding body Cancer Institute NSW
Project Team Dr Martin Ebert, Mrs Kristie Harrison, Associate Professor Helen Warren-Forward, Conjoint Professor Peter Greer
Scheme Research Infrastructure Grants
Role Investigator
Funding Start 2005
Funding Finish 2005
GNo G0185063
Type Of Funding Not Known
Category UNKN
UON Y

Real-time dosimetry for intensity-modulated radiotherapy$9,000

Funding body: Calvary Mater Newcastle Hospital

Funding body Calvary Mater Newcastle Hospital
Project Team

Peter Greer

Scheme Margaret Mitchell Research Grant
Role Lead
Funding Start 2005
Funding Finish 2005
GNo
Type Of Funding Other Public Sector - Local
Category 2OPL
UON N

20042 grants / $75,000

Image-based in vivo patient and organ localisation in external beam radiotherapy$58,000

Funding body: Cure Cancer Australia Foundation

Funding body Cure Cancer Australia Foundation
Project Team Conjoint Professor Peter Greer
Scheme Research Grant
Role Lead
Funding Start 2004
Funding Finish 2004
GNo G0183186
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

Production of diagnostic-quality X-rays from a megavoltage radiotherapy beam$17,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Dr Martin Ebert, Conjoint Professor Peter Greer
Scheme Research Grant
Role Investigator
Funding Start 2004
Funding Finish 2004
GNo G0183750
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y
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Research Supervision

Number of supervisions

Completed9
Current7

Total current UON EFTSL

Masters0.15
PhD2.95

Current Supervision

Commenced Level of Study Research Title / Program / Supervisor Type
2016 PhD Linear Accelerator Quality Assurance for Modern Radiotherapy Clinical Practice
PhD (Physics), Faculty of Science and Information Technology, The University of Newcastle
Principal Supervisor
2015 PhD Investigations of EPID Based Dosimetry Methods for use in MRI-Linac Radiotherapy
PhD (Physics), Faculty of Science and Information Technology, The University of Newcastle
Principal Supervisor
2015 PhD Improved Prostate Tumour Identification and Delineation Using Multiparametric Magnetic Resonance Imaging
PhD(Magnetic Resonance in Med), Faculty of Health and Medicine, The University of Newcastle
Principal Supervisor
2014 PhD Remote EPID-Based Dosimetry for Credentialing Radiation Therapies
PhD (Physics), Faculty of Science and Information Technology, The University of Newcastle
Principal Supervisor
2014 Masters The Use of 3D Ultrasound in the Radiation Therapy Simulation of Breast Cancer
M Philosophy (Med RadiationSc), Faculty of Health and Medicine, The University of Newcastle
Co-Supervisor
2013 PhD In Vivo Dosimetry and Intrafraction Motion During Prostate Radiotherapy
PhD (Physics), Faculty of Science and Information Technology, The University of Newcastle
Principal Supervisor
2013 PhD Investigations of EPID Based Dosimetry Methods for Use in MRI-Linac Radiotherapy
PhD (Physics), Faculty of Science and Information Technology, The University of Newcastle
Principal Supervisor

Past Supervision

Year Level of Study Research Title / Program / Supervisor Type
2016 PhD Real-Time Radiotherapy Error Detection Using Transit Beam Image Processing
PhD (Electrical Engineering), Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2016 PhD Real-Time Radiotherapy Error Detection Using Transit Beam Image Processing
PhD (Electrical Engineering), Faculty of Engineering and Built Environment, The University of Newcastle
Co-Supervisor
2015 PhD Development of Magnetic Resonance Imaging Based Prostate Treatment Planning
PhD (Physics), Faculty of Science and Information Technology, The University of Newcastle
Principal Supervisor
2013 PhD Investigation of Magnetic Resonance lmaging for Prostate Radiation Therapy Planning With Cone-Beam CT-Based Image Guided Radiation Therapy
PhD (Physics), Faculty of Science and Information Technology, The University of Newcastle
Principal Supervisor
2013 Masters Development of Epid-Based Real-Time Dosimetry and Geometry in Radiation Therapy
M Philosophy (Medical Physics), Faculty of Science and Information Technology, The University of Newcastle
Principal Supervisor
2013 Masters Development of Epid-Based Real-Time Dosimetry and Geometry in Radiation Therapy
M Philosophy (Medical Physics), Faculty of Engineering and Built Environment, The University of Newcastle
Principal Supervisor
2012 PhD Investigation of a Modified Electronic Portal Imaging Device for Improving Dosimetry in Radiotherapy
PhD (Physics), Faculty of Science and Information Technology, The University of Newcastle
Principal Supervisor
2012 PhD Improvement of EPID-based Techniques for Dosimetry and Investigation of Linac Mechanical Performance in Advanced Radiotherapy
PhD (Physics), Faculty of Science and Information Technology, The University of Newcastle
Principal Supervisor
2011 Masters Electronic Portal Imaging for Verification of Intensity Modulated Radiotherapy
M Philosophy (Physics), Faculty of Science and Information Technology, The University of Newcastle
Principal Supervisor
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Conjoint Professor Peter Greer

Position

Conjoint Professor
Medical Physics Group
School of Mathematical and Physical Sciences
Faculty of Science and Information Technology

Focus area

Physics

Contact Details

Email peter.greer@newcastle.edu.au
Phone (02) 4014 3689
Fax (02) 4014 3169

Office

Room 5.09 C, Radiation Oncology Department
Building Mater Hospital
Location Mater

,
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