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Staff Profile

Career Summary

Biography

Professor Dunkley's research is focused on signal transduction in neuronal and endocrine tissues and especially on protein phosphorylation.

Professor Dunkley has published 108 articles in peer reviewed journals and a further 14 refereed reviews and book chapters. His life time citations are 2880, his h-index is 27 and his average number of citations per article is 28. In 2011the number of citations was over 160. Professor Dunkley was invited by Nature Protocols to write a protocol based on two of his earlier papers which have together been cited 637 times. Since 2004 he has worked on the activation of tyrosine hydroxylase by protien phosphorylation and his review in J Neurochemistry has been cited 145 times.

Professor Dunkley has maintained a strong collaboration and mentoring role with young researchers in Brazil and has published 20 papers with these colleagues.

Professor Dunkley has a post-doctoral fellow and two PhD students working with him in 2012.

Grants: Professor Dunkley had continuous support from the NHMRC for 31 years until he retired for research in which he was the first named chief investigator. He has also been involved in many other collaborative NHMRC grants as a secondary CI. Professor Dunkley has also had grants from the ARC and many other funding agencies.

Recognition: Professor Dunkley has presented his research at 7 overseas conferences over the last 10 years with 5 being invited presentations.

In 2002 Professor Dunkley received the Hunter Medical Research Institute award for research excellence in the form of a $10,000 prize.

Professor Dunkley has been the neuroscience representative on the ARC biological sciences panel for 3 years and on an NHMRC RGIC on four occasions, including being the deputy chair of the cellular neuroscience panel in 1999 and deputy chair of the molecular neuroscience panel in 2006. He was on the Medicine and Public Health committee of the ERA in 2010 and the New Zealand PBRF committee in 2012.

Professor Dunkley was the President (2002-2003) of the International Society for Neurochemistry (ISN). He still serves as a member of the ISN finance committee. In addition he is a member of the Asian Pacific Society for Neurochemistry (APSN) council.

Professor Dunkley was the Foundation Head of The School of Biomedical Sciences at The University of Newcastle (1998-2002) and was the Pro Vice-Chancellor (Health) in 2010-2011. In 2012 he was the Director of the Hunter Medical Research Institute.

Qualifications

PhD, University of Melbourne, 31/12/1973
Bachelor of Science (Honours), University of Melbourne, 31/12/1971
Bachelor of Science, University of Melbourne, 31/12/1970

Research

Research keywords

Catecholamines
Depression
Parkinsons' disease
Protein chemistry
Signal transduction
Tyrosine hydroxylase
protein phosphorylation

Research expertise

My basic training is that of a protein chemist and I work in the field of cellular and molecular biology. My research focuses on signal transduction mechanisms in neuronal and endocrine tissues and especially on protein phosphorylation.

I have focussed on a number of key proteins and especially myelin basic protein that is essential for myelin structure, synapsin I that controls neurotransmitter release and tyrosine hydroxylase that is the rate limiting enzyme in catecholamine synthesis. I have investigated these proteins in the context of diseases including Multiple Sclerosis, Parkinsons' disease, depression and anxiety. My focus recently has been on been investigating the phosphorylation of tyrosine hydroxylase at Ser19, Ser31 and Ser40 and tyrosine hydroxylase activity in a number of tissues from the brain and from the adrenal medulla; the tissues have been collected from a range of animal models of stress and from human postmortem Parkinsons' disease patients.

I have also had an interest in nutritional biochemistry undertaking occasional studies on the uptake of dissolved nutrients in the Sydney rock oyster; the use of blood glucose monitors in diabetics; the teratogenic and oxidative consequences of ethanol consumption and the effects of vitamin A deficiency on gastrointestinal structure and function.

Fields of Research

Code	Description	Percentage
110900	Neurosciences	50
060100	Biochemistry And Cell Biology	40
110199	Medical Biochemistry And Metabolomics Not Elsewhere Classified	10

Memberships

ARC Committee member

AO Biological Sciences Committee 1996-1998

Committee/Associations (relevant to research).

International Society for Neurochemistry
NHMRC RGIC Committees 1992-1994
The American Society for Neurochemistry
The Australian Society for Biochemistry and Molecular Biology

Editorial Board.

Member 1992-1995 - European Journal of Pharmacology
Member 1991-1994 - Journal of Molecular Neuroscience
Member 1993-1997 - Journal of Neurochemistry

Appointments

Member New Zealand Performance Based Research Fund (New Zealand)	01/07/2011 - 01/12/2012
Member ERA Medicine and Public Health Committee (Australia)	01/01/2010 - 01/12/2010
Invited to Chair Molecular Neuroscience Panel NHMRC (Australia)	01/01/2007 - 01/12/2007
Deputy Chair Molecular Neuroscience Panel NHMRC (Australia)	01/01/2006 - 01/12/2006
Consultant in Restrospective Analysis of Research Grants NHMRC (Australia)	01/01/2006 - 01/12/2006
Consultant in Biomedical Sciences Griffith University (Australia)	01/01/2005 - 01/06/2006
Consultant in Biomedical Sciences University of Western Sydney (Australia)	01/01/2005 - 01/07/2005
President International Society for Neurochemistry	01/01/2001 - 01/12/2003
Deputy Chair Neuroscience DP NHMRC (Australia)	01/01/2000 - 01/12/2000
Treasurer International Society for Neurochemistry	01/01/1998 - 01/12/2001

Awards

Research Award.

2002	Award for Research Excellence HMRI (Australia)

Invitations

The Laurie Austin Lecture Australian Neuroscience Society, New Zealand (Keynote Address)	2011
IBN Lecture Brazil Neuroscience Society, Brazil (Keynote Address)	2008
Plenary Lecturer Japanese Society for Neurochemistry, Japan (Conference Presentation - non published.)	2002

Administrative

Administrative expertise

Member of the Griffith and University of Western Sydney Medical School Strategic Advisory Groups

Foundation Head, School of Biomedical Sciences

Member of the Executive of Faculty of Medicine and Health Sciences

Co-ordinator of Space for the Campus

University Strategic Planning Task Force elected by Academic Senate

Assistant Dean Finance and Personnel/Deputy Director, Medical School

University Planning and Resources Committee elected by the University Senate

Faculty of Medicine Structure Review Committee

Head of Medical Biochemistry (1988-1999)

Teaching

Teaching keywords

Biochemistry
Medical Biochemistry
Neurochemistry
Neuroscience

Teaching expertise

B Nutrition and Dietetics

Professional Skills for Laboratory Scientists-B Biomedical Science

Biomedical Sciences Degree and Biomedical Science Hons

International Development Programme Visiting Medical Specialist

B Medicine

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Publications

No publications.

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Grants and Funding

Summary

Number of grants	72
Total funding	$8,162,666

For project grants received where the lead institution is other than the University of Newcastle, details are shown in italics.

- Indicates that the researcher may be seeking students for this project.

Click on a grant title below to expand the full details for that specific grant.

2012 (1 grants)

Human tyrosine hydroxylase isoforms and susceptibility of dopaminergic neurons to degeneration in Parkinson's disease$354,601
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Associate Professor Phillip Dickson, Emeritus Professor Peter Dunkley, Associate Professor Kay Double
Scheme		Role
Project Grant		Investigator
Total Amount	Funding Start	Funding Finish
$354,601	2012	2014
GNo:G1100113

2011 (1 grants)

Brain Mechanisms Conferring Psychostimulant Addiction$25,000
Funding Body: University of Newcastle

Project Team
Doctor Chris Dayas, Emeritus Professor Peter Dunkley, Doctor Doug Smith
Scheme		Role
Near Miss Grant		Investigator
Total Amount	Funding Start	Funding Finish
$25,000	2011	2011
GNo:G1001052

2010 (1 grants)

The central neural pathway that controls the release of catecholaines from the adrenal medulla: It is impaired in hypertension?$24,686
Funding Body: Hunter Children`s Research Foundation

Project Team
Doctor Larisa Bobrovskaya, Associate Professor Ann Goodchild, Emeritus Professor Peter Dunkley
Scheme		Role
Research Grant		Investigator
Total Amount	Funding Start	Funding Finish
$24,686	2010	2010
GNo:G0900143

2009 (2 grants)

An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry$495,000
Funding Body: ARC (Australian Research Council)

Project Team
Laureate Professor John Aitken, Professor Adam McCluskey, Doctor Mark Baker, Doctor Nikki Verrills, Professor Marcel Maeder, Doctor Xiaojing Zhou, Professor Eileen McLaughlin, Associate Professor Brett Nixon, Doctor Shaun Roman, Conjoint Professor Ray Rose, Professor Hugh Dunstan, Professor Christopher Grof, Professor Roger Smith, Conjoint Professor Peter Gibson, Conjoint Professor Alison Jones, Professor Mike Calford, Conjoint Professor Keith Jones, Doctor Rick Thorne, Emeritus Professor Peter Dunkley, Professor Paul Foster, Conjoint Professor Leonie Ashman, Professor Gordon Burns, Associate Professor Phillip Dickson, Professor John Rostas, Professor Rodney Scott, Associate Professor Paul Tooney, Professor Phil Hansbro, Professor Pablo Moscato, Professor Paul Dastoor, Professor Peter Lewis
Scheme		Role
Linkage Infrastructure Equipment & Facilities (LIEF)		Investigator
Total Amount	Funding Start	Funding Finish
$495,000	2009	2009
GNo:G0189122

An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry$50,000
Funding Body: ARC (Australian Research Council)

Project Team
Laureate Professor John Aitken, Professor Adam McCluskey, Doctor Mark Baker, Doctor Nikki Verrills, Professor Marcel Maeder, Doctor Xiaojing Zhou, Professor Eileen McLaughlin, Associate Professor Brett Nixon, Doctor Shaun Roman, Conjoint Professor Ray Rose, Professor Hugh Dunstan, Professor Christopher Grof, Professor Roger Smith, Conjoint Professor Peter Gibson, Conjoint Professor Alison Jones, Professor Mike Calford, Conjoint Professor Keith Jones, Doctor Rick Thorne, Emeritus Professor Peter Dunkley, Professor Paul Foster, Conjoint Professor Leonie Ashman, Professor Gordon Burns, Associate Professor Phillip Dickson, Professor John Rostas, Professor Rodney Scott, Associate Professor Paul Tooney, Professor Phil Hansbro, Professor Pablo Moscato, Professor Paul Dastoor, Professor Peter Lewis
Scheme		Role
Linkage Infrastructure Equipment & Facilities (LIEF) Partner funding		Investigator
Total Amount	Funding Start	Funding Finish
$50,000	2009	2009
GNo:G0189948

2008 (3 grants)

Dopamine mechanisms conferring resilience to depression: A new antidepressant target$538,500
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Trevor Day, Emeritus Professor Peter Dunkley, Professor David Pow, Doctor Doug Smith
Scheme		Role
Project Grant		Investigator
Total Amount	Funding Start	Funding Finish
$538,500	2008	2010
GNo:G0187604

Neurobiology of sustained phosphorylation$18,800
Funding Body: University of Newcastle - Faculty of Health

Project Team
Doctor Larisa Bobrovskaya, Emeritus Professor Peter Dunkley
Scheme		Role
Pilot Grant		Investigator
Total Amount	Funding Start	Funding Finish
$18,800	2008	2008
GNo:G0189081

Asian Pacific Society for Neurochemistry Biennial Meeting, Hope Island, Shanghai, China, 23/6/2008 - 26/6/2008$1,904
Funding Body: University of Newcastle

Project Team
Emeritus Professor Peter Dunkley
Scheme		Role
Travel Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$1,904	2008	2008
GNo:G0188912

2007 (4 grants)

Heat Shock Proteins in Myometrium$437,750
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Roger Smith, Emeritus Professor Peter Dunkley, Professor Alistair Sim, Conjoint Associate Professor Andrew Bisits
Scheme		Role
Project Grant		Investigator
Total Amount	Funding Start	Funding Finish
$437,750	2007	2009
GNo:G0186406

Differential regulation of human tyrosine hydroxylase isoforms and the development of Parkinson's disease$312,750
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Associate Professor Phillip Dickson, Emeritus Professor Peter Dunkley, Associate Professor Kay Double
Scheme		Role
Project Grant		Investigator
Total Amount	Funding Start	Funding Finish
$312,750	2007	2009
GNo:G0186394

Vulnerability to depression: the role of dopamine pathways$20,000
Funding Body: University of Newcastle

Project Team
Professor Trevor Day, Emeritus Professor Peter Dunkley, Doctor Doug Smith, Professor David Pow
Scheme		Role
Near Miss Grant		Investigator
Total Amount	Funding Start	Funding Finish
$20,000	2007	2007
GNo:G0187196

7th International Brain Research Organisation World Congress of Neuroscience, Melbourne, 12/7/2007 - 17/7/2007$1,075
Funding Body: University of Newcastle

Project Team
Emeritus Professor Peter Dunkley
Scheme		Role
Travel Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$1,075	2007	2007
GNo:G0187748

2006 (6 grants)

Advanced technology for transcriptomics, genomics and gene mapping$850,000
Funding Body: ARC (Australian Research Council)

Project Team
Professor Rodney Scott, Professor Ian Dawes, Professor Ronald Trent, Professor Nicholas Hunt, Emeritus Professor Peter Bergquist, Professor Mark Baker, Emeritus Professor Peter Dunkley, Dr Ruby Lin, Conjoint Professor Peter Gibson, Professor Alistair Sim
Scheme		Role
Linkage Infrastructure Equipment & Facilities (LIEF)		Investigator
Total Amount	Funding Start	Funding Finish
$850,000	2006	2006
GNo:G0185547

PRC - Priority Research Centre for Bioinformatics, Biomarker Discovery & Information-Based Medicine (CIBM)$621,143
Funding Body: University of Newcastle

Project Team
Professor Pablo Moscato, Professor Rodney Scott, Professor John Rostas, Professor John Forbes, Conjoint Professor Peter Hersey, Conjoint Professor Stephen Ackland, Conjoint Professor Wayne Smith, Emeritus Professor Peter Dunkley, Conjoint Professor Leonie Ashman, Professor John Attia, Associate Professor Phillip Dickson, Associate Professor Liz Milward, Professor Alistair Sim, Associate Professor Paul Tooney, Associate Professor Regina Berretta, Conjoint Professor David Sibbritt, Conjoint Professor Chris Levi, Professor Xu Dong Zhang, Conjoint Associate Professor Patricia Crock, Conjoint Associate Professor Jeannette Lechner-Scott
Scheme		Role
Priority Research Centre		Investigator
Total Amount	Funding Start	Funding Finish
$621,143	2006	2013
GNo:G0186919

PRC - Priority Research Centre for Brain & Mental Health Research (CBMHR)$524,282
Funding Body: University of Newcastle

Project Team
Conjoint Professor Chris Levi, Professor Amanda Baker, Professor Mike Calford, Professor Trevor Day, Emeritus Professor Peter Dunkley, Professor Michael Hazelton, Professor Andrew Heathcote, Professor Brian Kelly, Conjoint Professor Vaughan Carr, Emeritus Professor Patricia Michie, Professor David Pow, Professor John Rostas, Professor Ulli Schall, Professor Alistair Sim, Professor Mike Startup
Scheme		Role
Priority Research Centre		Investigator
Total Amount	Funding Start	Funding Finish
$524,282	2006	2013
GNo:G0186947

Differential regulation of human tyrosine hydroxyase isoforms and susceptibility of dopaminergic neurons to degeneration$10,000
Funding Body: University of Newcastle

Project Team
Associate Professor Phillip Dickson, Emeritus Professor Peter Dunkley, Associate Professor Kay Double
Scheme		Role
Near Miss Grant		Investigator
Total Amount	Funding Start	Funding Finish
$10,000	2006	2006
GNo:G0186079

Asian Pacific Society for Neurochemistry (APSN), 2-5 July 2006$1,448
Funding Body: University of Newcastle

Project Team
Emeritus Professor Peter Dunkley
Scheme		Role
Travel Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$1,448	2006	2006
GNo:G0186518

BioRad Mini-PROTEAN3 Electrophoresis system$995
Funding Body: Hunter Medical Research Institute

Project Team
Conjoint Professor Leonie Ashman, Associate Professor Phillip Dickson, Emeritus Professor Peter Dunkley, Professor John Rostas, Professor Judith Scott, Professor Alistair Sim, Doctor Nikki Verrills
Scheme		Role
Equipment Grant		Investigator
Total Amount	Funding Start	Funding Finish
$995	2006	2006
GNo:G0187280

2005 (4 grants)

A novel mechanism for the maintenance of catecholamine synthesis$351,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Emeritus Professor Peter Dunkley, Associate Professor Phillip Dickson
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$351,000	2005	2007
GNo:G0184211

High throughput proteomics - Thermo Finnigan ProteomeX LCQ Integrated Proteomicis Workstation$207,189
Funding Body: ARC (Australian Research Council)

Project Team
Laureate Professor John Aitken, Professor Eileen McLaughlin, Professor Peter Lewis, Conjoint Associate Professor Renate Griffith, Conjoint Professor Ray Rose, Emeritus Professor John Patrick, Associate Professor David McCurdy, Professor Adam McCluskey, Emeritus Professor Ellak Von Nagy-Felsobuki, Emeritus Professor Peter Dunkley, Associate Professor Phillip Dickson, Professor John Rostas, Conjoint Professor Leonie Ashman, Professor Gordon Burns, Professor Paul Foster, Conjoint Professor Peter Gibson, Professor Roger Smith, Professor Alistair Sim, Associate Professor Paul Tooney, Dr Fraser Ross
Scheme		Role
Linkage Infrastructure Equipment & Facilities (LIEF)		Investigator
Total Amount	Funding Start	Funding Finish
$207,189	2005	2005
GNo:G0184185

Control of Dopamine synthesis and Parkinsons' disease$10,000
Funding Body: Hunter Medical Research Institute

Project Team
Associate Professor Phillip Dickson, Emeritus Professor Peter Dunkley
Scheme		Role
Project Grant		Investigator
Total Amount	Funding Start	Funding Finish
$10,000	2005	2005
GNo:G0185977

Regulation of Human Tyrosine Hydroxylase Isoforms by Hierarchical Phosphorylation$8,000
Funding Body: University of Newcastle

Project Team
Associate Professor Phillip Dickson, Emeritus Professor Peter Dunkley
Scheme		Role
Project Grant		Investigator
Total Amount	Funding Start	Funding Finish
$8,000	2005	2005
GNo:G0184779

2004 (1 grants)

Biacore3000-Expansion of Proteomics Facility$187,341
Funding Body: ARC (Australian Research Council)

Project Team
Professor Alistair Sim, Laureate Professor John Aitken, Emeritus Professor Peter Dunkley, Professor John Rostas, Associate Professor Phillip Dickson, Conjoint Professor Leonie Ashman, Professor Roger Smith, Professor Gordon Burns, Professor Adam McCluskey, Associate Professor Paul Tooney, Dr Fraser Ross, Conjoint Professor Ray Rose
Scheme		Role
Linkage Infrastructure Equipment & Facilities (LIEF)		Investigator
Total Amount	Funding Start	Funding Finish
$187,341	2004	2004
GNo:G0183030

2003 (4 grants)

Hierarchical Phosphorylation of Tyrosine Hydroxylase is Dependent on the Activation Sequence of Signaling Pathways.$135,000
Funding Body: ARC (Australian Research Council)

Project Team
Associate Professor Phillip Dickson, Emeritus Professor Peter Dunkley
Scheme		Role
Discovery Projects		Investigator
Total Amount	Funding Start	Funding Finish
$135,000	2003	2004
GNo:G0182096

Molecular Mechanisms of Lead-Induced Neurotoxicity$15,000
Funding Body: University of Newcastle

Project Team
Emeritus Professor Peter Dunkley, Dr Perry Hartfield
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$15,000	2003	2003
GNo:G0182478

Signal transduction in clutured astrocytes in relation to morphology and intracellular hydrogen ion concentration (pHi)$10,000
Funding Body: University of Newcastle

Project Team
Conjoint Professor Richard Rodnight, Emeritus Professor Peter Dunkley
Scheme		Role
Project Grant		Investigator
Total Amount	Funding Start	Funding Finish
$10,000	2003	2003
GNo:G0182429

Sparke Helmore Prime Television Corporate Triathlon Award for Research Excellence$10,000
Funding Body: Hunter Medical Research Institute

Project Team
Emeritus Professor Peter Dunkley
Scheme		Role
Research Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$10,000	2003	2003
GNo:G0182732

2002 (4 grants)

Proteomic and Genomic Analysis Facility.$473,332
Funding Body: Wellcome Trust

Project Team
Professor Alistair Sim, Emeritus Professor Peter Dunkley, Professor John Rostas, Professor Rodney Scott, Conjoint Professor Leonie Ashman
Scheme		Role
Major Equipment Award		Investigator
Total Amount	Funding Start	Funding Finish
$473,332	2002	2004
GNo:G0181527

Control of catecholamine synthesis and secretion by angiotensin II$270,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Emeritus Professor Peter Dunkley, Associate Professor Phillip Dickson
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$270,000	2002	2004
GNo:G0180883

Peltier Thermal Cycler and associated equipment essential for establishing cDNA Retroviral Libraries$21,315
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor Leonie Ashman, Dr Petranel Ferrao, Professor Gordon Burns, Professor Alistair Sim, Emeritus Professor Peter Dunkley, Professor John Rostas, Associate Professor Phillip Dickson, Professor Dirk Van Helden, Dr Perry Hartfield
Scheme		Role
Equipment Grant		Investigator
Total Amount	Funding Start	Funding Finish
$21,315	2002	2002
GNo:G0181919

Heat Shock Protein Function in Nerve Cell Death$13,000
Funding Body: University of Newcastle

Project Team
Dr Perry Hartfield, Emeritus Professor Peter Dunkley
Scheme		Role
Project Grant		Investigator
Total Amount	Funding Start	Funding Finish
$13,000	2002	2002
GNo:G0181348

2001 (4 grants)

The Effect of Lead on Cells$26,000
Funding Body: Hunter Medical Research Institute

Project Team
Emeritus Professor Peter Dunkley, Dr Perry Hartfield
Scheme		Role
NIB Hunter Golf Professionals Charity Golf Day		Chief Investigator
Total Amount	Funding Start	Funding Finish
$26,000	2001	2001
GNo:G0180752

Control of Catecholamine Synthesis by Tyrosine Hydroxylase.$13,000
Funding Body: University of Newcastle

Project Team
Emeritus Professor Peter Dunkley, Associate Professor Phillip Dickson, Emeritus Professor Ellak Von Nagy-Felsobuki, Professor Alistair Sim
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$13,000	2001	2001
GNo:G0180125

Thermocycler with 96 well sample block for PCR reactions. Class II Biological Safety Cabinet. Liquid Nitrogen storage Dewar & Transport Dewar$11,770
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Emeritus Professor Peter Dunkley, Professor Alistair Sim, Professor Dirk Van Helden, Professor Robert Callister
Scheme		Role
Equipment Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$11,770	2001	2001
GNo:G0181178

Thermocycler with 96 well sample block for PCR reactions. Class II Biological Safety Cabinet. Liquid Nitrogen storage Dewar & Transport Dewar$11,770
Funding Body: University of Newcastle

Project Team
Emeritus Professor Peter Dunkley, Professor Alistair Sim, Professor Dirk Van Helden, Professor Robert Callister
Scheme		Role
University/NHMRC Equipment Grant Funds		Chief Investigator
Total Amount	Funding Start	Funding Finish
$11,770	2001	2001
GNo:G0181179

2000 (4 grants)

Neurolucida Imaging System.$24,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor Loris Chahl, Associate Professor Paul Tooney, Emeritus Professor Peter Dunkley, Professor John Rostas
Scheme		Role
Equipment Grant		Investigator
Total Amount	Funding Start	Funding Finish
$24,000	2000	2000
GNo:G0179167

Control of Catecholamine Synthesis by Tyrosine Hydroxylase.$14,500
Funding Body: ARC (Australian Research Council)

Project Team
Emeritus Professor Peter Dunkley, Associate Professor Phillip Dickson, Emeritus Professor Ellak Von Nagy-Felsobuki
Scheme		Role
Small Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$14,500	2000	2000
GNo:G0178980

Regulating the Regulator: Using Immunochemical Tools to Reveal How CaMPK-II is Controlled by Phosporylation In Vivo.$13,500
Funding Body: University of Newcastle

Project Team
Professor John Rostas, Emeritus Professor Peter Dunkley, Dr Martin Cammarota, Dr Sabine Fieuw-Makaroff
Scheme		Role
Project Grant		Investigator
Total Amount	Funding Start	Funding Finish
$13,500	2000	2000
GNo:G0178869

Mechanisms of ATP-stimulated phosphorylation and activation of tyrosine hydroxylase.$12,000
Funding Body: University of Newcastle

Project Team
Dr Tat Cheah, Emeritus Professor Peter Dunkley, Conjoint Professor David Powis
Scheme		Role
Project Grant		Investigator
Total Amount	Funding Start	Funding Finish
$12,000	2000	2000
GNo:G0178904

1999 (4 grants)

Mechanisms of angiotensin-stimulated phosphorylation & activation of tyrosine hydroxylase$203,316
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Emeritus Professor Peter Dunkley, Conjoint Professor David Powis, Dr Tat Cheah
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$203,316	1999	2001
GNo:G0178348

FPLC Protein Purification System$16,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Alistair Sim, Professor John Rostas, Emeritus Professor Peter Dunkley, Associate Professor Phillip Dickson
Scheme		Role
Equipment Grant		Investigator
Total Amount	Funding Start	Funding Finish
$16,000	1999	1999
GNo:G0180790

Determination of the Phosphorylation States of Tyrosine Hyroxylase in Bovine Adrenal Chromaffin Cells by Electrospray Mass Spectrometry.$13,500
Funding Body: ARC (Australian Research Council)

Project Team
Emeritus Professor Ellak Von Nagy-Felsobuki, Emeritus Professor Peter Dunkley
Scheme		Role
Small Grant		Investigator
Total Amount	Funding Start	Funding Finish
$13,500	1999	1999
GNo:G0178016

Development of a cellular model to study regulation of neurotransmitter synthesis$9,000
Funding Body: University of Newcastle

Project Team
Associate Professor Phillip Dickson, Emeritus Professor Peter Dunkley
Scheme		Role
Project Grant		Investigator
Total Amount	Funding Start	Funding Finish
$9,000	1999	1999
GNo:G0178050

1998 (3 grants)

Molecular Dynamics Storm 860 Tri-mode Analysis System$35,000
Funding Body: Ramaciotti Foundations

Project Team
Professor Alistair Sim, Professor John Rostas, Emeritus Professor Peter Dunkley, Dr Stephen Bunn, Dr Tat Cheah, Conjoint Professor Kenneth Beagley, Conjoint Professor Ray Rose, Professor Judith Scott, Doctor Cheng Chan, Professor Roger Smith
Scheme		Role
Research Grant		Investigator
Total Amount	Funding Start	Funding Finish
$35,000	1998	1998
GNo:G0177453

Identification of protein phosphatases acting on Tyrosine Hydroxylase in bovine adrenal chromaffin cells.$19,000
Funding Body: University of Newcastle

Project Team
Emeritus Professor Peter Dunkley, Professor Alistair Sim, Dr Tat Cheah
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$19,000	1998	1998
GNo:G0177219

Determination of the Phoshorylation States of Tyrosine Hydroxylase in Bovine Adrenal Chromaffin Cells by Electrospray Mass Spectrometry$12,000
Funding Body: ARC (Australian Research Council)

Project Team
Emeritus Professor Ellak Von Nagy-Felsobuki, Emeritus Professor Peter Dunkley
Scheme		Role
Small Grant		Investigator
Total Amount	Funding Start	Funding Finish
$12,000	1998	1998
GNo:G0177304

1997 (6 grants)

Newcastle Protein - A Protein Sequencing and Analysis Unit of the Newcastle Biomolecular Research Facility.$200,000
Funding Body: Department of Education, Training & Youth Affairs

Project Team
Emeritus Professor Peter Dunkley
Scheme		Role
Research Infrastructure Equipment & Facilities (RIEF)		Chief Investigator
Total Amount	Funding Start	Funding Finish
$200,000	1997	1997
GNo:G0176524

Role of Protein Phosphorylation in the Control of Glutamate Release from Nerve Terminals.$178,409
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Emeritus Professor Peter Dunkley, Dr B Walmsley, Professor Alistair Sim, Dr Stephen Bunn
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$178,409	1997	1999
GNo:G0176252

Exocytosis and the Calcium Regulation of Phospholipase C Isozymes$143,284
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Emeritus Professor Peter Dunkley, Dr Stephen Bunn
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$143,284	1997	1999
GNo:G0176253

Modulation of Neurotransmitted Release by Carboxyl-methylation and tyrosine Phosphorylation of Protein Phosphatase type 2A.$18,000
Funding Body: ARC (Australian Research Council)

Project Team
Professor Alistair Sim, Doctor Paul Brent, Emeritus Professor Peter Dunkley
Scheme		Role
Small Grant		Investigator
Total Amount	Funding Start	Funding Finish
$18,000	1997	1997
GNo:G0176731

Biomedical applications using an electrospray mass spectrometer$15,000
Funding Body: ARC (Australian Research Council)

Project Team
Emeritus Professor Ellak Von Nagy-Felsobuki, Emeritus Professor Peter Dunkley
Scheme		Role
Small Grant		Investigator
Total Amount	Funding Start	Funding Finish
$15,000	1997	1997
GNo:G0176739

International society for Neurochemistry, Boston, USA, 20-25 July 1997$2,500
Funding Body: University of Newcastle

Project Team
Emeritus Professor Peter Dunkley
Scheme		Role
Travel Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$2,500	1997	1997
GNo:G0179452

1996 (3 grants)

Microscope and infra-red camera$42,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Dr Pankaj Sah, Dr B Walmsley, Emeritus Professor Peter Dunkley, Professor Dirk Van Helden
Scheme		Role
Equipment Grant		Investigator
Total Amount	Funding Start	Funding Finish
$42,000	1996	1996
GNo:G0175473

Effects of angiotensin II on tyrosine hydroxylase activity and phosphorylation in bovine adrenal chromaffin cells.$12,000
Funding Body: University of Newcastle

Project Team
Emeritus Professor Peter Dunkley, Dr Tat Cheah, Dr Stephen Bunn
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$12,000	1996	1996
GNo:G0175838

Establishment of techniques for preparing genetically engineered molecules to study the regulation of neuronal and cellular function$12,000
Funding Body: University of Newcastle

Project Team
Professor John Rostas, Emeritus Professor Peter Dunkley, Professor Robert Callister
Scheme		Role
Project Grant		Investigator
Total Amount	Funding Start	Funding Finish
$12,000	1996	1996
GNo:G0175744

1995 (6 grants)

The mechanism and significance of tyrosine hydroxylase phosphorylation.$166,805
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Emeritus Professor Peter Dunkley, Dr Stephen Bunn, Dr Tat Cheah
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$166,805	1995	1997
GNo:G0174549

Regulation of signal transduction pathways by sigma ligands: mechanisms and significance.$144,626
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Doctor Paul Brent, Emeritus Professor Peter Dunkley
Scheme		Role
Project Grant		Investigator
Total Amount	Funding Start	Funding Finish
$144,626	1995	1997
GNo:G0174539

Neuroscience Group$59,000
Funding Body: Department of Education, Training & Youth Affairs

Project Team
Emeritus Professor Peter Dunkley
Scheme		Role
Research Infrastructure Block Grant (RIBG)		Chief Investigator
Total Amount	Funding Start	Funding Finish
$59,000	1995	1995
GNo:G0175584

95APP. High resolution purification of intra-cellular signalling proteins from brain by FPLC.$20,000
Funding Body: Ramaciotti Foundations

Project Team
Professor Alistair Sim, Emeritus Professor Peter Dunkley, Professor John Rostas
Scheme		Role
Research Grant		Investigator
Total Amount	Funding Start	Funding Finish
$20,000	1995	1995
GNo:G0174696

Establishment of new model systems and techniques for studying neurotransmision$9,000
Funding Body: University of Newcastle

Project Team
Emeritus Professor Peter Dunkley, Professor John Rostas, Dr B Walmsley
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$9,000	1995	1995
GNo:G0174902

15th Biennial Mtg of Intern. Society for Neurochemistry, Japan, 2-7 July$2,312
Funding Body: University of Newcastle

Project Team
Emeritus Professor Peter Dunkley
Scheme		Role
Travel Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$2,312	1995	1995
GNo:G0176857

1994 (5 grants)

Mechanism of Nitric Oxide Modulation of Secretion in Autonomic Ganglia$22,500
Funding Body: National Heart Foundation of Australia

Project Team
Emeritus Professor Peter Dunkley, Professor John Rostas
Scheme		Role
Grant-In-Aid		Chief Investigator
Total Amount	Funding Start	Funding Finish
$22,500	1994	1994
GNo:G0175235

Establishment of new model systems and techniques for studying neurotransmission$13,500
Funding Body: ARC (Australian Research Council)

Project Team
Professor John Rostas, Emeritus Professor Peter Dunkley, Dr B Walmsley
Scheme		Role
Small Grant		Investigator
Total Amount	Funding Start	Funding Finish
$13,500	1994	1994
GNo:G0174822

94 APP The effect of Vitamin A deficiency on intestinal structure, function and mucosal repair$11,000
Funding Body: University of Newcastle

Project Team
Ms Rosemary Warden, Ted O'Loughlin, Emeritus Professor Peter Dunkley
Scheme		Role
Project Grant		Investigator
Total Amount	Funding Start	Funding Finish
$11,000	1994	1994
GNo:G0174784

The control of tyrosine hydroxylase activity by protein phosphorylation.$6,000
Funding Body: University of Newcastle

Project Team
Emeritus Professor Peter Dunkley, Dr Stephen Bunn, Professor Alistair Sim
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$6,000	1994	1994
GNo:G0174737

Do sigma binding site ligands modulate neurotransmission by molecular mechanisms involving protein phosphorylation in neuronal tissue$5,000
Funding Body: University of Newcastle

Project Team
Doctor Paul Brent, Emeritus Professor Peter Dunkley, Professor Alistair Sim
Scheme		Role
Project Grant		Investigator
Total Amount	Funding Start	Funding Finish
$5,000	1994	1994
GNo:G0174732

1993 (2 grants)

Autophosphorylation of Calcium/Calmodulin-stimulated Protein Kinase II.$243,361
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Emeritus Professor Peter Dunkley
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$243,361	1993	1995
GNo:G0173162

'Intern. Society for Neurochemistry', Montpellier, France, 22 - 27 August 1993$2,500
Funding Body: University of Newcastle

Project Team
Emeritus Professor Peter Dunkley
Scheme		Role
Travel Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$2,500	1993	1993
GNo:G0174385

1992 (2 grants)

92,93,94GRANT. The Regulation Of Protein Phosphatases In The Brain$183,006
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Alistair Sim, Emeritus Professor Peter Dunkley, Professor John Rostas
Scheme		Role
Project Grant		Investigator
Total Amount	Funding Start	Funding Finish
$183,006	1992	1994
GNo:G0174274

The Role Of Inositol (1,4,5) Trisphosphate In The Adrenal Chromaffin Cell$134,018
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Dr Stephen Bunn, Emeritus Professor Peter Dunkley
Scheme		Role
Project Grant		Investigator
Total Amount	Funding Start	Funding Finish
$134,018	1992	1994
GNo:G0174260

1991 (2 grants)

Calmodulin Kinases: Roles in Hormone and Neurotransmitter Release.$45,826
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Emeritus Professor Peter Dunkley
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$45,826	1991	1991
GNo:G0173950

Beta Scintillation Spectrometer$37,552
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor David Powis, Emeritus Professor Peter Dunkley, Professor John Rostas, Emeritus Professor Anthony Smith
Scheme		Role
Equipment Grant		Investigator
Total Amount	Funding Start	Funding Finish
$37,552	1991	1991
GNo:G0173965

Edit

Research Supervision

Number of current supervisions	2
Total current UoN PhD EFTSL	0.4

For supervisions undertaken at an institution other that the University of Newcastle, details are shown in italics, and the institution name is listed below the program name.

Current Supervision

Commenced	Proposed Completion	Program	Supervisor Type	Research Title
2011	2015	PhD (Medical Biochemistry)	Co-Supervisor	The Interaction of Tyrosine Hydroxylase with Alpha Synuclein: a Role in Parkinson's Disease
2007	2007	Honours Biochemistry & Cell Biology University of Newcastle	Co-Supervisor	Catecholamine binding sites on tyrosine hydroxylase

Past Supervision

Year	Program	Supervisor Type	Research Title
2013	PhD (Medical Biochemistry)	Co-Supervisor	Investigation of Catecholamine Inhibition in Tyrosine Hydroxylase
2012	PhD (Medical Biochemistry)	Principal Supervisor	Neurobiological Consequences of Stress: Tyrosine Hydroxylase Phosphorylation in Response to Stress
2012	PhD (Anatomy)	Co-Supervisor	Dopaminergic Pathway Imbalance in the Neurobiology of Depression
2010	PhD (Medical Biochemistry)	Co-Supervisor	Differential Distribution of Tyrosine Hydroxylase Isoforms and Phosphorylation in Parkinson Disease
2009	PhD (Medical Biochemistry)	Co-Supervisor	Acute Regulation of Tyrosine Hydroxylase
2006	Honours Biochemistry & Cell Biology University of Newcastle	Co-Supervisor	The effects of antidepressant drugs on catecholamine synthesis
2005	Honours Biochemistry & Cell Biology University of Newcastle	Co-Supervisor	Catecholamine binding sites in tyrosine hydroxylase
2005	Honours Biochemistry & Cell Biology University of Newcastle	Co-Supervisor	A model for the sustained activation of tyrosine hydroxylase
2004	Honours Biochemistry & Cell Biology University of Newcastle	Co-Supervisor	Regulation of tyrosine hydroxylase phosphorylation by Angiotensin II
2003	Honours Biochemistry & Cell Biology University of Newcastle	Co-Supervisor	The regulation of tyrosine hydroxylase
2002	PHD Biochemistry & Cell Biology University of Newcastle	Co-Supervisor	Characterisation of tyrosine hydroxylase phosphorylation by mass spectrosopy
2001	Honours Biochemistry & Cell Biology University of Newcastle	Sole Supervisor	The control of tyrosine hydroxylase phosphorylation in bovine adrenal chromaffin cells
2000	Masters Biochemistry & Cell Biology University of Newcastle	Co-Supervisor	The regulation of phospholipase c1 in bovine adrenal chromaffin cells
2000	PHD Biochemistry & Cell Biology University of Newcastle	Sole Supervisor	Angiotensin II-stimulated tyrosine hydroxylase activity and phosphorylation in bovine adrenal chromaffin cells
1998	PHD Biochemistry & Cell Biology University of Newcastle	Co-Supervisor	Vitamin A deficiency and intestinal structure and function in the rat
1997	PHD Biochemistry & Cell Biology University of Newcastle	Co-Supervisor	Embryo-fetotoxicity of prenatal alcohol exposure and its relationship to oxidative stress

Edit

Emeritus Professor Peter Dunkley

Work Phone	(02) 4921 5600
Fax	(02) 4921 6903
Email	Peter.Dunkley@newcastle.edu.au
Positions	Emeritus Professor School of Biomedical Sciences and Pharmacy Faculty of Health and Medicine The University of Newcastle, Australia
Positions	HMRI Strategic Consultant Faculty of Health and Medicine The University of Newcastle, Australia
Focus Area	Medical Biochemistry
Office	MSB506, Medical Sciences Building, Callaghan University Drive Callaghan NSW 2308 Australia
URL:	www.newcastle.edu.au/profile/peter-dunkley

Staff Directory

Staff Profile

Career Summary

Biography

Qualifications

Research

Research keywords

Research expertise

Fields of Research

Memberships

ARC Committee member

Committee/Associations (relevant to research).

Editorial Board.

Appointments

Awards

Research Award.

Invitations

Administrative

Administrative expertise

Teaching

Teaching keywords

Teaching expertise

Publications

Grants and Funding

Summary

2012 (1 grants)

Human tyrosine hydroxylase isoforms and susceptibility of dopaminergic neurons to degeneration in Parkinson's disease$354,601Funding Body: NHMRC (National Health & Medical Research Council)

2011 (1 grants)

Brain Mechanisms Conferring Psychostimulant Addiction$25,000Funding Body: University of Newcastle

2010 (1 grants)

The central neural pathway that controls the release of catecholaines from the adrenal medulla: It is impaired in hypertension?$24,686Funding Body: Hunter Children`s Research Foundation

2009 (2 grants)

An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry$495,000Funding Body: ARC (Australian Research Council)

An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry$50,000Funding Body: ARC (Australian Research Council)

2008 (3 grants)

Dopamine mechanisms conferring resilience to depression: A new antidepressant target$538,500Funding Body: NHMRC (National Health & Medical Research Council)

Neurobiology of sustained phosphorylation$18,800Funding Body: University of Newcastle - Faculty of Health

Asian Pacific Society for Neurochemistry Biennial Meeting, Hope Island, Shanghai, China, 23/6/2008 - 26/6/2008$1,904Funding Body: University of Newcastle

2007 (4 grants)

Heat Shock Proteins in Myometrium$437,750Funding Body: NHMRC (National Health & Medical Research Council)

Differential regulation of human tyrosine hydroxylase isoforms and the development of Parkinson's disease$312,750Funding Body: NHMRC (National Health & Medical Research Council)

Vulnerability to depression: the role of dopamine pathways$20,000Funding Body: University of Newcastle

7th International Brain Research Organisation World Congress of Neuroscience, Melbourne, 12/7/2007 - 17/7/2007$1,075Funding Body: University of Newcastle

2006 (6 grants)

Advanced technology for transcriptomics, genomics and gene mapping$850,000Funding Body: ARC (Australian Research Council)

PRC - Priority Research Centre for Bioinformatics, Biomarker Discovery & Information-Based Medicine (CIBM)$621,143Funding Body: University of Newcastle

PRC - Priority Research Centre for Brain & Mental Health Research (CBMHR)$524,282Funding Body: University of Newcastle

Differential regulation of human tyrosine hydroxyase isoforms and susceptibility of dopaminergic neurons to degeneration$10,000Funding Body: University of Newcastle

Asian Pacific Society for Neurochemistry (APSN), 2-5 July 2006$1,448Funding Body: University of Newcastle

BioRad Mini-PROTEAN3 Electrophoresis system$995Funding Body: Hunter Medical Research Institute

2005 (4 grants)

A novel mechanism for the maintenance of catecholamine synthesis$351,000Funding Body: NHMRC (National Health & Medical Research Council)

High throughput proteomics - Thermo Finnigan ProteomeX LCQ Integrated Proteomicis Workstation$207,189Funding Body: ARC (Australian Research Council)

Control of Dopamine synthesis and Parkinsons' disease$10,000Funding Body: Hunter Medical Research Institute

Regulation of Human Tyrosine Hydroxylase Isoforms by Hierarchical Phosphorylation$8,000Funding Body: University of Newcastle

2004 (1 grants)

Biacore3000-Expansion of Proteomics Facility$187,341Funding Body: ARC (Australian Research Council)

2003 (4 grants)

Hierarchical Phosphorylation of Tyrosine Hydroxylase is Dependent on the Activation Sequence of Signaling Pathways.$135,000Funding Body: ARC (Australian Research Council)

Molecular Mechanisms of Lead-Induced Neurotoxicity$15,000Funding Body: University of Newcastle

Signal transduction in clutured astrocytes in relation to morphology and intracellular hydrogen ion concentration (pHi)$10,000Funding Body: University of Newcastle

Sparke Helmore Prime Television Corporate Triathlon Award for Research Excellence$10,000Funding Body: Hunter Medical Research Institute

2002 (4 grants)

Proteomic and Genomic Analysis Facility.$473,332Funding Body: Wellcome Trust

Control of catecholamine synthesis and secretion by angiotensin II$270,000Funding Body: NHMRC (National Health & Medical Research Council)

Peltier Thermal Cycler and associated equipment essential for establishing cDNA Retroviral Libraries$21,315Funding Body: NHMRC (National Health & Medical Research Council)

Heat Shock Protein Function in Nerve Cell Death$13,000Funding Body: University of Newcastle

2001 (4 grants)

The Effect of Lead on Cells$26,000Funding Body: Hunter Medical Research Institute

Control of Catecholamine Synthesis by Tyrosine Hydroxylase.$13,000Funding Body: University of Newcastle

Thermocycler with 96 well sample block for PCR reactions. Class II Biological Safety Cabinet. Liquid Nitrogen storage Dewar & Transport Dewar$11,770Funding Body: NHMRC (National Health & Medical Research Council)

Thermocycler with 96 well sample block for PCR reactions. Class II Biological Safety Cabinet. Liquid Nitrogen storage Dewar & Transport Dewar$11,770Funding Body: University of Newcastle

2000 (4 grants)

Neurolucida Imaging System.$24,000Funding Body: NHMRC (National Health & Medical Research Council)

Control of Catecholamine Synthesis by Tyrosine Hydroxylase.$14,500Funding Body: ARC (Australian Research Council)

Regulating the Regulator: Using Immunochemical Tools to Reveal How CaMPK-II is Controlled by Phosporylation In Vivo.$13,500Funding Body: University of Newcastle

Mechanisms of ATP-stimulated phosphorylation and activation of tyrosine hydroxylase.$12,000Funding Body: University of Newcastle

1999 (4 grants)

Mechanisms of angiotensin-stimulated phosphorylation & activation of tyrosine hydroxylase$203,316Funding Body: NHMRC (National Health & Medical Research Council)

FPLC Protein Purification System$16,000Funding Body: NHMRC (National Health & Medical Research Council)

Human tyrosine hydroxylase isoforms and susceptibility of dopaminergic neurons to degeneration in Parkinson's disease$354,601
Funding Body: NHMRC (National Health & Medical Research Council)

Brain Mechanisms Conferring Psychostimulant Addiction$25,000
Funding Body: University of Newcastle

The central neural pathway that controls the release of catecholaines from the adrenal medulla: It is impaired in hypertension?$24,686
Funding Body: Hunter Children`s Research Foundation

An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry$495,000
Funding Body: ARC (Australian Research Council)

An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry$50,000
Funding Body: ARC (Australian Research Council)

Dopamine mechanisms conferring resilience to depression: A new antidepressant target$538,500
Funding Body: NHMRC (National Health & Medical Research Council)

Neurobiology of sustained phosphorylation$18,800
Funding Body: University of Newcastle - Faculty of Health

Asian Pacific Society for Neurochemistry Biennial Meeting, Hope Island, Shanghai, China, 23/6/2008 - 26/6/2008$1,904
Funding Body: University of Newcastle

Heat Shock Proteins in Myometrium$437,750
Funding Body: NHMRC (National Health & Medical Research Council)

Differential regulation of human tyrosine hydroxylase isoforms and the development of Parkinson's disease$312,750
Funding Body: NHMRC (National Health & Medical Research Council)

Vulnerability to depression: the role of dopamine pathways$20,000
Funding Body: University of Newcastle

7th International Brain Research Organisation World Congress of Neuroscience, Melbourne, 12/7/2007 - 17/7/2007$1,075
Funding Body: University of Newcastle

Advanced technology for transcriptomics, genomics and gene mapping$850,000
Funding Body: ARC (Australian Research Council)

PRC - Priority Research Centre for Bioinformatics, Biomarker Discovery & Information-Based Medicine (CIBM)$621,143
Funding Body: University of Newcastle

PRC - Priority Research Centre for Brain & Mental Health Research (CBMHR)$524,282
Funding Body: University of Newcastle

Differential regulation of human tyrosine hydroxyase isoforms and susceptibility of dopaminergic neurons to degeneration$10,000
Funding Body: University of Newcastle

Asian Pacific Society for Neurochemistry (APSN), 2-5 July 2006$1,448
Funding Body: University of Newcastle

BioRad Mini-PROTEAN3 Electrophoresis system$995
Funding Body: Hunter Medical Research Institute

A novel mechanism for the maintenance of catecholamine synthesis$351,000
Funding Body: NHMRC (National Health & Medical Research Council)

High throughput proteomics - Thermo Finnigan ProteomeX LCQ Integrated Proteomicis Workstation$207,189
Funding Body: ARC (Australian Research Council)

Control of Dopamine synthesis and Parkinsons' disease$10,000
Funding Body: Hunter Medical Research Institute

Regulation of Human Tyrosine Hydroxylase Isoforms by Hierarchical Phosphorylation$8,000
Funding Body: University of Newcastle

Biacore3000-Expansion of Proteomics Facility$187,341
Funding Body: ARC (Australian Research Council)

Hierarchical Phosphorylation of Tyrosine Hydroxylase is Dependent on the Activation Sequence of Signaling Pathways.$135,000
Funding Body: ARC (Australian Research Council)

Molecular Mechanisms of Lead-Induced Neurotoxicity$15,000
Funding Body: University of Newcastle

Signal transduction in clutured astrocytes in relation to morphology and intracellular hydrogen ion concentration (pHi)$10,000
Funding Body: University of Newcastle

Sparke Helmore Prime Television Corporate Triathlon Award for Research Excellence$10,000
Funding Body: Hunter Medical Research Institute

Proteomic and Genomic Analysis Facility.$473,332
Funding Body: Wellcome Trust

Control of catecholamine synthesis and secretion by angiotensin II$270,000
Funding Body: NHMRC (National Health & Medical Research Council)

Peltier Thermal Cycler and associated equipment essential for establishing cDNA Retroviral Libraries$21,315
Funding Body: NHMRC (National Health & Medical Research Council)

Heat Shock Protein Function in Nerve Cell Death$13,000
Funding Body: University of Newcastle

The Effect of Lead on Cells$26,000
Funding Body: Hunter Medical Research Institute

Control of Catecholamine Synthesis by Tyrosine Hydroxylase.$13,000
Funding Body: University of Newcastle

Thermocycler with 96 well sample block for PCR reactions. Class II Biological Safety Cabinet. Liquid Nitrogen storage Dewar & Transport Dewar$11,770
Funding Body: NHMRC (National Health & Medical Research Council)

Thermocycler with 96 well sample block for PCR reactions. Class II Biological Safety Cabinet. Liquid Nitrogen storage Dewar & Transport Dewar$11,770
Funding Body: University of Newcastle

Neurolucida Imaging System.$24,000
Funding Body: NHMRC (National Health & Medical Research Council)

Control of Catecholamine Synthesis by Tyrosine Hydroxylase.$14,500
Funding Body: ARC (Australian Research Council)

Regulating the Regulator: Using Immunochemical Tools to Reveal How CaMPK-II is Controlled by Phosporylation In Vivo.$13,500
Funding Body: University of Newcastle

Mechanisms of ATP-stimulated phosphorylation and activation of tyrosine hydroxylase.$12,000
Funding Body: University of Newcastle

Mechanisms of angiotensin-stimulated phosphorylation & activation of tyrosine hydroxylase$203,316
Funding Body: NHMRC (National Health & Medical Research Council)

FPLC Protein Purification System$16,000
Funding Body: NHMRC (National Health & Medical Research Council)

Determination of the Phosphorylation States of Tyrosine Hyroxylase in Bovine Adrenal Chromaffin Cells by Electrospray Mass Spectrometry.$13,500
Funding Body: ARC (Australian Research Council)

Development of a cellular model to study regulation of neurotransmitter synthesis$9,000
Funding Body: University of Newcastle

Molecular Dynamics Storm 860 Tri-mode Analysis System$35,000
Funding Body: Ramaciotti Foundations

Identification of protein phosphatases acting on Tyrosine Hydroxylase in bovine adrenal chromaffin cells.$19,000
Funding Body: University of Newcastle

Determination of the Phoshorylation States of Tyrosine Hydroxylase in Bovine Adrenal Chromaffin Cells by Electrospray Mass Spectrometry$12,000
Funding Body: ARC (Australian Research Council)

Newcastle Protein - A Protein Sequencing and Analysis Unit of the Newcastle Biomolecular Research Facility.$200,000
Funding Body: Department of Education, Training & Youth Affairs

Role of Protein Phosphorylation in the Control of Glutamate Release from Nerve Terminals.$178,409
Funding Body: NHMRC (National Health & Medical Research Council)

Exocytosis and the Calcium Regulation of Phospholipase C Isozymes$143,284
Funding Body: NHMRC (National Health & Medical Research Council)

Modulation of Neurotransmitted Release by Carboxyl-methylation and tyrosine Phosphorylation of Protein Phosphatase type 2A.$18,000
Funding Body: ARC (Australian Research Council)

Biomedical applications using an electrospray mass spectrometer$15,000
Funding Body: ARC (Australian Research Council)

International society for Neurochemistry, Boston, USA, 20-25 July 1997$2,500
Funding Body: University of Newcastle

Microscope and infra-red camera$42,000
Funding Body: NHMRC (National Health & Medical Research Council)

Effects of angiotensin II on tyrosine hydroxylase activity and phosphorylation in bovine adrenal chromaffin cells.$12,000
Funding Body: University of Newcastle

Establishment of techniques for preparing genetically engineered molecules to study the regulation of neuronal and cellular function$12,000
Funding Body: University of Newcastle

The mechanism and significance of tyrosine hydroxylase phosphorylation.$166,805
Funding Body: NHMRC (National Health & Medical Research Council)

Regulation of signal transduction pathways by sigma ligands: mechanisms and significance.$144,626
Funding Body: NHMRC (National Health & Medical Research Council)

Neuroscience Group$59,000
Funding Body: Department of Education, Training & Youth Affairs

95APP. High resolution purification of intra-cellular signalling proteins from brain by FPLC.$20,000
Funding Body: Ramaciotti Foundations

Establishment of new model systems and techniques for studying neurotransmision$9,000
Funding Body: University of Newcastle

15th Biennial Mtg of Intern. Society for Neurochemistry, Japan, 2-7 July$2,312
Funding Body: University of Newcastle

Mechanism of Nitric Oxide Modulation of Secretion in Autonomic Ganglia$22,500
Funding Body: National Heart Foundation of Australia

Establishment of new model systems and techniques for studying neurotransmission$13,500
Funding Body: ARC (Australian Research Council)

94 APP The effect of Vitamin A deficiency on intestinal structure, function and mucosal repair$11,000
Funding Body: University of Newcastle

The control of tyrosine hydroxylase activity by protein phosphorylation.$6,000
Funding Body: University of Newcastle

Do sigma binding site ligands modulate neurotransmission by molecular mechanisms involving protein phosphorylation in neuronal tissue$5,000
Funding Body: University of Newcastle

Autophosphorylation of Calcium/Calmodulin-stimulated Protein Kinase II.$243,361
Funding Body: NHMRC (National Health & Medical Research Council)

'Intern. Society for Neurochemistry', Montpellier, France, 22 - 27 August 1993$2,500
Funding Body: University of Newcastle

92,93,94GRANT. The Regulation Of Protein Phosphatases In The Brain$183,006
Funding Body: NHMRC (National Health & Medical Research Council)

The Role Of Inositol (1,4,5) Trisphosphate In The Adrenal Chromaffin Cell$134,018
Funding Body: NHMRC (National Health & Medical Research Council)

Calmodulin Kinases: Roles in Hormone and Neurotransmitter Release.$45,826
Funding Body: NHMRC (National Health & Medical Research Council)

Beta Scintillation Spectrometer$37,552
Funding Body: NHMRC (National Health & Medical Research Council)