Profile Image

Staff Profile

Edit

Career Summary

Biography

Professor Paul Foster is the Director of the Priority Research Centre for Asthma and Respiratory Disease; the Virus, Infection/Immunity, Vaccines and Asthma Program, Hunter Medical Research Institute and the Cooperative Research Centre (CRC) for Asthma and Airways (Newcastle node). He also currently holds the Chair of Immunology, School of Biomedical Sciences and Pharmacy, Faculty of Health, University of Newcastle. He is also a visiting Professor at Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. He serves as an Associate Editor of the American Journal of Respiratory Cell and Molecular Biology and the Journal of Pharmacology and Therapeutics, and is on the Editorial Boards of a number of leading international immunology/allergy journals. Professor Foster's research focuses on understanding the molecular and cellular basis of asthma, allergy, respiratory disorders, and chronic inflammation. His research program focuses on translational approaches directed towards the development of novel anti-inflammatory therapies. Professor Foster's research findings are published in the most highly ranked medical and biomedical science journals (e.g. Nature Immunology and Journal of Experimental Medicine). Essential Science Indicators metrics places his team on the forefront of his field internationally. Professor Foster receives numerous and ongoing invitations to speak and chair sessions and leading international conferences in immunology and respiratory medicine (e.g. American Academy of Asthma, Allergy and Immunology, Keystone, Cold Spring Harbor, International Congress on Immunology and International Eosinophil meeting). The importance of his team's work has been recognised through award of over $10.5 million in direct funding (since 2003) through Australian national competitive grants.

Since 1995 Professor Foster's laboratory has focused on the biology of T cells and granulocytes, and on signaling by cytokines and chemokines pertinent to regulating allergic inflammatory responses, in particular asthma. In the last 5 years we have extended our focus to understanding the relationship between inflammation induced by infection (viruses, bacteria and microbial products), at various times through life, on the subsequent development of the T cell repertoire and on chronic inflammation in the lung. A focus on the role of microRNAs in the regulation of inflammation is also a main focus.

Professor Foster's activities have been supported through grants from the NHMRC (program and project grants), Australian Research Council (Discovery and LIEF grants), Human Frontiers Science Foundation, and through the CRC for Asthma and Airways. Professor Foster actively contributes to peer review at a national and international level (e.g. NHMRC; fellowship, program and project reviews/grant panel; Wellcome Trust; and leading international journals (e.g. J. of Clin. Invest., J. of Exp. Med., and Nature).

Professor Foster is also on the Editorial Board of:

• American Journal of Respiratory Cell & Molecular Biology

• Pharmacology & Therapeutics (Associate Editor)

• Current Molecular Medicine

• Journal Inflammation and Allergy

• Clinical and Experimental Allergy

Qualifications

  • PhD, Australian National University, 15/04/1988
  • Bachelor of Science (Honours), University of Western Australia

Research

Research keywords

  • Allergy
  • Asthma
  • Chronic Inflammation
  • Immunology
  • Leukocyte Biology

Research expertise

Current research in my laboratory primarily aims at defining the key cellular and molecular processes that underlie the development of allergic disease (lung, skin and gastrointestinal tract) and of viral (RSV and influenza) induced pulmonary inflammation. We are particularly interested in the molecular events that predispose to remodeling of the airways in chronic disease and the subsequent impact on lung function. In particular, projects are focusing on the biology of CD4+ Th2 cells, CD8+ T cells and eosinophils, and in signaling arrangements between cytokine and chemokine systems that pertain to allergic disease, viral induced pathogenesis and viral induced exacerbation of asthma. Our aim is to develop integrative concepts on molecular mechanisms of pathogenesis by employing an approach that is multifactorial ranging from transgenic systems to the identification of novel gene products. The laboratory has established in vivo models of asthma (acute and chronic), allergic cutaneous disease and of eosinophil and lymphocyte homing to sites of allergen or viral provocation. Models of RSV infection in the presence and absence of allergic inflammation are also established. These models, in conjunction with mice that are factor deficient or transgenic (constitutive and inducible systems that are airway specific, and T cell transgenic systems), are currently being employed to define the individual role of inflammatory cells and cytokines/chemokines in the pathophysiology of allergic and viral disorders and viral induced exacerbation of allergic inflammation. Collectively, this approach is providing a fundamental platform for the identification of key targets for potential therapeutic intervention in these diseased states and models for the development of novel anti-inflammatory approaches. Models of leukocyte trafficking and pathogenesis are combined with experimental programs at a cellular level to enhance the understanding of the molecular basis of disease. Novel mechanisms to attenuate allergic and viral induced disease are also being explored. We have also established models of chronic obstructive pulmonary disease (COPD).

Current PhD and Honours projects within my team aim to gather an understanding in:

• the role of miRNA in asthma and infection

• the role of viruses in inducing asthma and COPD

• miRNA regulation of leukocyte differentiation

• the innate immune system in severe asthma

Fields of Research

CodeDescriptionPercentage
110799Immunology Not Elsewhere Classified75
110200Cardiovascular Medicine And Haematology25

Memberships

ARC Committee member

  • Member

Committee/Associations (relevant to research).

  • Member - CRC for Asthma and Airways
  • Editor - (Small Granting Agencies State Foundations and Councils)
  • member - American Society for Immunology
  • member - International Eosinophil Society
  • member - International Mucosal Immunology Society
  • member - The Australian Lung foundation
  • member - The Australian Society for Immunolgy
  • member - The Thoracic Society of Australia and New Zealand

Editorial Board.

  • Editor - Journal Inflammation and Allergy
  • Editor - Clinical and Experimental Allergy
  • Editor - American Journal of Respiratory Cell and Molecular Biology
  • Associate Editor - Pharmacology & Therapeutics

Appointments

Visiting Professorship
Harvard University, MA (United States)
01/01/2010

Awards

Research Award.

2010Research Excellence
HMRI (Australia)
1999Australian Academy of Science and The Royal Society Travelling Fellowship
ANU (Australia)
1997Human Frontiers Science Programme International Collaborative Grant
ANU (Australia)
1996The British council Collaborative Research Award
ANU (Australia)
1996The John curtin School of Medical Research, Howard Florey Young Investigators Award
ANU (Australia)
1996The Asthma foundation of NSW, The Jean Jeavons grant for Asthma Research
ANU (Australia)
1994Australian Academy of Science and The Royal Society Travelling Fellowship
ANU (Australia)
1983Commonwealth Postgraduate Research Scholarship
ANU (Australia)

Research Funding

2005CRC for Asthma and Airways
University of Newcastle (Australia)
2003NHMRC Programme Grant 2003-2007
ANU (Australia)

Invitations

Congress of the European Academy of Allergy and Clinical Immunology
29th Conference, United Kingdom (Invited Speaker)
2010
The American Academy of Asthma, Allergy and Immunology (AAAAI)
65th Annual Meeting - Mini-symposium (educational section), United States (Invited Speaker)
2010
Biennial Symposium International Eosinophil Society
6th Conference, Belgium (Invited Speaker)
2009
The American Academy of Asthma, Allergy and Immunology (AAAAI)
64th Annual Meeting - Mini-symposium (educational section), United States (Invited Speaker)
2009
The American Academy of Asthma, Allergy and Immunology (AAAAI)
63nd Annual Meeting - Mini-symposium (educational section)., United States (Invited Speaker)
2008
Molecular Therapeutics of Cancer
Gordon Conference, United States (Invited Speaker)
2007
Biennial Symposium International Eosinophil Society
5th Conference, United States (Invited Speaker)
2007
International Congress of Immunology
14th Conference, Brazil (Invited Speaker)
2007
The American Academy of Asthma, Allergy and Immunology (AAAAI)
61st Annual Meeting - Mini-symposium (educational section), United States (Invited Speaker)
2006
The American Academy of Asthma, Allergy and Immunology (AAAAI)
60th Annual Meeting - Symposium Chemokines and Receptors, United States (Invited Speaker)
2005
25th International Symposium
Collegium Internationalale Allergologicum, Sweden (Invited speaker)
2004
12th International Congress on Immunology
4th Annual Conerence of FOCIS, Canada (Invited speaker)
2004

Collaboration

I have extensive national and international collaborations and associations with leading investigators and biotechnology and pharmaceutical companies. For example:

• Professor Andrew Mackenzie, Laboratory of Molecular Biology, Cambridge University, UK.

• Professor K Takeda and S Akira, Osaka University, Osaka Japan.

• Professor Marc Rothenberg, Children’s Hospital Medical Centre, Cincinnati, OH.

• Professor Helene Rosenberg, National Institute of Allergy and Infectious Diseases, National Institutes of Health, USA.

• Professor Richard Stevens, Harvard Medical School, Boston MA.

• Professor Sebastian Johnston, Imperial College, London UK.

• Professor Pardric Fallon, Trinity College, Dublin, Ireland.

• GSK.

• MedImmune Inc, Washington DC, USA.

• Commonwealth Serum Laboratories, Parkville, Melbourne, Australia.

Administrative

Administrative expertise

• Hunter Medical Research Institute Building Committee

• Research Committee - Member

• Academic Senate - Member

• Animal Services Research Facility, Advisory Committee, Sub-committee - Member

• Analytical and Biomolecular Research Facility Advisory

• Strategic Research Advisory Panel HMRI - Member

• Research Committee, School of Biomedical Sciences and Pharmacy, University of Newcastle - Member

• Steering Committee, Vaccines, Infection, Virus and Asthma Group, HMRI - Member

Teaching

Teaching keywords

  • Biomedical Sciences
  • Immunology
  • Medicine
  • Pharmacy

Teaching expertise

• Immunology

• Research Commercialisation

Edit

Publications

No publications.

Edit

Grants and Funding

Summary

Number of grants76
Total funding$15,857,354

For project grants received where the lead institution is other than the University of Newcastle, details are shown in italics.

- Indicates that the researcher may be seeking students for this project.

Click on a grant title below to expand the full details for that specific grant.

2013 (4 grants)

HMRI-MRSP Infrastructure (12-16) - VIVA Program$486,671
Funding Body: Hunter Medical Research Institute

Project Team
Professor Paul Foster, Conjoint Professor Peter Gibson
SchemeRole
MRSP Infrastructure GrantChief Investigator
Total AmountFunding StartFunding Finish
$486,67120132013
GNo:G1300567

Molecular and cellular characterisation of TLR7 signalling in rhinovirus-induced asthma exacerbation$25,000
Funding Body: Hunter Medical Research Institute

Project Team
Professor Joerg Mattes, Professor Paul Foster
SchemeRole
Near MissInvestigator
Total AmountFunding StartFunding Finish
$25,00020132013
GNo:G1300692

DP73 Digital colour and monochrome camera + cellSens software + Xcite120 fluorescence lamp illuminator$20,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Paul Foster, Doctor Alan Hsu, Professor Phil Hansbro, Professor Joerg Mattes, Doctor Katie Baines, Associate Professor Jodie Simpson, Professor Rakesh Kumar, Doctor Nicole Hansbro, Doctor Steven Maltby, Doctor Ming Yang, Doctor Gerard Kaiko, Doctor Jay Horvat, Doctor Simon Keely, Mr Andrew Jarnicki, Doctor Michael Fricker
SchemeRole
Equipment GrantChief Investigator
Total AmountFunding StartFunding Finish
$20,00020132013
GNo:G1201186

American Academy of Allergy Asthma & Immunology Annual Meeting, Henry B Gonzalez Convention Centre, San Antonio USA, 22 - 26 February 2013$2,000
Funding Body: University of Newcastle - Faculty of Health

Project Team
Professor Paul Foster
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,00020132014
GNo:G1300349

2012 (11 grants)

Targeting miRNA to inhibit leukocyte differentiation: a novel anti-inflammatory approach for the treatment of asthma$590,886
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Paul Foster, Professor Ian Young
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$590,88620122014
GNo:G1100129

Understanding the mechanisms of steroid resistant inflammatory pathways in mouse models of asthma: potential new treatment approaches$514,551
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Paul Foster, Doctor Ming Yang
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$514,55120122014
GNo:G1100099

HMRI MRSP Infrastructure (11-12)- VIVA$486,671
Funding Body: Hunter Medical Research Institute

Project Team
Professor Paul Foster, Conjoint Professor Peter Gibson
SchemeRole
MRSP Infrastructure GrantChief Investigator
Total AmountFunding StartFunding Finish
$486,67120122012
GNo:G1101137

BD FACSAria III Cell Sorter: 3 laser 10-colour Flow Cytometer$180,000
Funding Body: ARC (Australian Research Council)

Project Team
Professor Paul Foster, Conjoint Professor Peter Gibson, Laureate Professor John Aitken, Professor Roger Smith, Professor Rodney Scott
SchemeRole
Linkage Infrastructure Equipment & Facilities (LIEF)Chief Investigator
Total AmountFunding StartFunding Finish
$180,00020122012
GNo:G1100746

BD FACSAria III Cell Sorter: 3 laser 10-colour Flow Cytometer$150,000
Funding Body: University of Newcastle

Project Team
Professor Paul Foster, Professor Trevor Day, Conjoint Professor Peter Gibson, Laureate Professor John Aitken, Professor Roger Smith, Professor Rodney Scott
SchemeRole
Equipment GrantChief Investigator
Total AmountFunding StartFunding Finish
$150,00020122012
GNo:G1100744

BD FACSAria III Cell Sorter: 3 laser 10-colour Flow Cytometer$122,927
Funding Body: Hunter Medical Research Institute

Project Team
Professor Paul Foster, Conjoint Professor Peter Gibson, Laureate Professor John Aitken, Professor Roger Smith, Professor Rodney Scott
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$122,92720122012
GNo:G1200668

SpectraMax M5e Multi-Mode Microplate Reader$50,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Paul Foster, Professor Phil Hansbro, Professor Joerg Mattes, Professor Rakesh Kumar, Doctor Nicole Hansbro, Doctor Ming Yang, Doctor Jay Horvat, Doctor Simon Keely, Mr Andrew Jarnicki, Doctor Linda Howland, Doctor Kelly Asquith
SchemeRole
Equipment GrantChief Investigator
Total AmountFunding StartFunding Finish
$50,00020122012
GNo:G1100975

Australia-Harvard Fellowship$36,000
Funding Body: Harvard Club of Australia Foundation

Project Team
Professor Paul Foster
SchemeRole
Australia-Harvard Fellowships Chief Investigator
Total AmountFunding StartFunding Finish
$36,00020122013
GNo:G1200214

Australia-Harvard Fellowship - Allen$26,000
Funding Body: Harvard Club of Australia Foundation

Project Team
Professor Paul Foster
SchemeRole
Australia-Harvard Fellowships Chief Investigator
Total AmountFunding StartFunding Finish
$26,00020122013
GNo:G1200238

Elucidating the mechanisms of steroid-resistant asthma$15,000
Funding Body: Hunter Medical Research Institute

Project Team
Doctor Jay Horvat, Professor Phil Hansbro, Professor Paul Foster
SchemeRole
Research GrantInvestigator
Total AmountFunding StartFunding Finish
$15,00020122013
GNo:G1200190

American Academy of Allergy Asthma and Immunology Annual Meeting 2012, Orlando, Florida, 2 - 6 March 2012$2,000
Funding Body: University of Newcastle - Faculty of Health

Project Team
Professor Paul Foster
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,00020122013
GNo:G1200407

2011 (11 grants)

Targeting microRNA (miRNA) as a unified therapeutic approach to the treatment of asthma and allergic inflammation$651,732
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Paul Foster, Professor Joerg Mattes, Professor Rakesh Kumar
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$651,73220112013
GNo:G1000262

Mast cell proteases suppress respiratory viral infections and allergic inflammation of the airways$642,561
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Paul Foster, Dr Michele Grimbaldeston
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$642,56120112013
GNo:G1000260

Establishment of a comprehensive regional biophysical analysis facility $500,000
Funding Body: ARC (Australian Research Council)

Project Team
Professor Peter Lewis, Professor Nicholas Dixon, Professor Eileen McLaughlin, Professor Adam McCluskey, Associate Professor Aaron Oakley, Professor Paul Foster, Laureate Professor John Aitken, Associate Professor Jennifer Beck, Dr Michael Kelso, Professor Graham Nicholson, Associate Professor Elizabeth Harry, Professor Ian Charles, Associate Professor Steven Djordjevic
SchemeRole
Linkage Infrastructure Equipment & Facilities (LIEF)Investigator
Total AmountFunding StartFunding Finish
$500,00020112011
GNo:G1000630

HMRI MRSP Infrastructure Grant (10-11) VIVA$485,452
Funding Body: Hunter Medical Research Institute

Project Team
Conjoint Professor Peter Gibson, Professor Paul Foster
SchemeRole
MRSP Infrastructure GrantInvestigator
Total AmountFunding StartFunding Finish
$485,45220112011
GNo:G1100162

Development of microbial bioproducts for the suppression of inflammation$285,000
Funding Body: ARC (Australian Research Council)

Project Team
Professor Phil Hansbro, Professor Paul Foster, Professor Rakesh Kumar
SchemeRole
Discovery ProjectsInvestigator
Total AmountFunding StartFunding Finish
$285,00020112013
GNo:G1000021

Establishment of a comprehensive regional biophysical analysis facility $230,000
Funding Body: ARC (Australian Research Council)

Project Team
Professor Peter Lewis, Professor Nicholas Dixon, Professor Eileen McLaughlin, Professor Adam McCluskey, Associate Professor Aaron Oakley, Professor Paul Foster, Laureate Professor John Aitken, Associate Professor Jennifer Beck, Dr Michael Kelso, Professor Graham Nicholson, Associate Professor Elizabeth Harry, Professor Ian Charles, Associate Professor Steven Djordjevic
SchemeRole
Linkage Infrastructure Equipment & Facilities (LIEF) Partner fundingInvestigator
Total AmountFunding StartFunding Finish
$230,00020112011
GNo:G1100484

DVCR Special Grant 2011$140,000
Funding Body: University of Newcastle

Project Team
Professor Paul Foster
SchemeRole
Special Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$140,00020112011
GNo:G1101011

Research microscope, confocal ready nikon eclipse 90i microscope$69,157
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Roger Smith, Conjoint Professor Tam Zakar, Associate Professor Jon Hirst, Doctor Kaushik Maiti, Doctor Gemma Madsen, Professor Rodney Scott, Conjoint Associate Professor Peter Wark, Professor Paul Foster, Professor Phil Hansbro, Mr Ian Wright
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$69,15720112011
GNo:G1100024

Maitland Cancer Appeal Committee Donation - Lung Cancer Mouse Model$50,000
Funding Body: Maitland Cancer Appeal Committee

Project Team
Professor Phil Hansbro, Professor Paul Foster, Doctor Gough Au
SchemeRole
Research Project Investigator
Total AmountFunding StartFunding Finish
$50,00020112011
GNo:G1100246

SCIREQ FlexiVentFX system + FlexiVentFX extension$45,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Phil Hansbro, Professor Paul Foster, Professor Joerg Mattes, Doctor Simon Keely, Doctor Jay Horvat, Doctor Nicole Hansbro, Doctor Ming Yang, Doctor Catherine Ptaschinski, Doctor Kelly Asquith, Doctor Gough Au, Conjoint Associate Professor Peter Wark, Laureate Professor John Aitken, Conjoint Professor Keith Jones, Professor Roger Smith, Professor Judith Black, Professor Rakesh Kumar, Professor Paul Hertzog
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$45,00020112011
GNo:G1100037

Sparke Helmore/NBN Triathlon Award for Research Excellence$15,000
Funding Body: Hunter Medical Research Institute

Project Team
Professor Paul Foster
SchemeRole
Research Excellence AwardChief Investigator
Total AmountFunding StartFunding Finish
$15,00020112011
GNo:G1000985

2010 (8 grants)

The role of microRNAs in the regulation of antiviral and inflammatory responses during experimental rhinovirus infection$583,500
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Joerg Mattes, Professor Paul Foster
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$583,50020102012
GNo:G0190183

HMRI MRSP Infrastructure Grant (09-10) - VIVA$397,696
Funding Body: Hunter Medical Research Institute

Project Team
Professor Paul Foster, Conjoint Professor Peter Gibson
SchemeRole
MRSP Infrastructure GrantChief Investigator
Total AmountFunding StartFunding Finish
$397,69620102010
GNo:G1000232

Laser microdissection microscopy system for cell and development biology$350,000
Funding Body: ARC (Australian Research Council)

Mechanisms of induction and progression of childhood asthma: investigations in a mouse model $240,750
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Rakesh Kumar, Professor Paul Foster, Dr Megan Hitchins
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$240,75020102012
GNo:G0900216

Laser microdissection microscopy system for cell and development biology$215,000
Funding Body: University of Newcastle

Buxco FinePointe software and FinePointe RC system for mice $39,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Paul Foster, Professor Phil Hansbro, Professor Joerg Mattes, Doctor Nicole Hansbro, Doctor Simon Phipps, Doctor Ming Yang, Doctor Kelly Asquith, Doctor Catherine Ptaschinski, Professor Rakesh Kumar, Professor Judith Black
SchemeRole
Equipment GrantChief Investigator
Total AmountFunding StartFunding Finish
$39,00020102010
GNo:G1000053

Molecular markers of reversible airway obstruction in early life and correlation with clinical wheezing patterns$19,842
Funding Body: Hunter Children`s Research Foundation

Project Team
Professor Joerg Mattes, Professor Paul Foster, Conjoint Associate Professor Bruce Whitehead, Doctor Ana Pereira De Siqueira
SchemeRole
Research GrantInvestigator
Total AmountFunding StartFunding Finish
$19,84220102010
GNo:G0900119

The 8th Asia Pacific Congress of Allergy, Asthma and Clinical Immunology, Singapore, 6 - 9 November 2010$2,000
Funding Body: University of Newcastle - Faculty of Health

Project Team
Professor Paul Foster
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,00020102011
GNo:G1000937

2009 (5 grants)

An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry$495,000
Funding Body: ARC (Australian Research Council)

An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry$50,000
Funding Body: ARC (Australian Research Council)

Coulter counter$41,150
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Paul Foster, Professor Phil Hansbro, Professor Joerg Mattes, Doctor Simon Phipps, Doctor Ming Yang, Doctor Nicole Hansbro, Doctor Kelly Asquith
SchemeRole
Equipment GrantChief Investigator
Total AmountFunding StartFunding Finish
$41,15020092009
GNo:G0189851

Development of novel therapeutic approaches for rhinovirus - induced asthma exacerbation$24,500
Funding Body: Hunter Medical Research Institute

Project Team
Professor Joerg Mattes, Professor Paul Foster, Conjoint Associate Professor Peter Wark
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$24,50020092009
GNo:G0189800

Immunisation against chlamydia-associated asthma$20,000
Funding Body: Rebecca L Cooper Medical Research Foundation Ltd

Project Team
Doctor Jay Horvat, Professor Phil Hansbro, Professor Paul Foster
SchemeRole
Research GrantInvestigator
Total AmountFunding StartFunding Finish
$20,00020092009
GNo:G0189629

2008 (7 grants)

The role of microRNAs as new anti-inflammatory targets for the treatment of asthma$600,375
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Paul Foster, Professor Rakesh Kumar, Assoc. Prof Klaus Matthaei, Professor Joerg Mattes
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$600,37520082010
GNo:G0187584

Targeting the shared beta-chain of the IL-3, IL-5 and GM-CSF receptors as therapy for allergic inflammation$585,375
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Paul Foster, Professor Angel Lopez
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$585,37520082010
GNo:G0187585

The mechanisms underlying pneumoviral-induced angiogenesis of the lung and its impact on the asthmatic response$541,875
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Paul Foster, Professor Judith Black
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$541,87520082010
GNo:G0187591

Role of IL-3 in allergic inflammation: modulation of basophils, mast cells, eosinophils and remodelling in asthma$235,050
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Paul Foster
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$235,05020082010
GNo:G0189190

Individually ventilated cages (IVC) and associated ventilator, holding boxes and water bottles$35,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Paul Foster, Professor Phil Hansbro, Professor Joerg Mattes, Doctor Simon Phipps, Doctor Ming Yang, Doctor Nicole Hansbro, Doctor Kelly Asquith
SchemeRole
Equipment GrantChief Investigator
Total AmountFunding StartFunding Finish
$35,00020082008
GNo:G0188541

MicroRNA and antagomirs in the regulation and suppression of interferon (IFN)-g and lipopolysaccharide (LPS) induced steroid-resistant airways hyperreactivity$24,250
Funding Body: Hunter Medical Research Institute

Project Team
Doctor Ming Yang, Professor Paul Foster
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$24,25020082008
GNo:G0188474

Therapeutic potential of targeting the IL-3/IL-5/GM-CSF common beta receptor to treat allergic inflammation and asthma$23,957
Funding Body: Hunter Medical Research Institute

Project Team
Doctor Kelly Asquith, Professor Paul Foster
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$23,95720082008
GNo:G0188460

2007 (9 grants)

HMRI - Viruses, Infection/Immunity, Vaccines and Asthma Research Program$692,213
Funding Body: Hunter Medical Research Institute

Project Team
Professor Paul Foster, Conjoint Professor Peter Gibson, Conjoint Professor Stephen Graves, Associate Professor Darren Shafren
SchemeRole
MRSP Infrastructure GrantChief Investigator
Total AmountFunding StartFunding Finish
$692,21320072009
GNo:G0187930

Influence of early-life viral infection on severity of murine chronic asthma and acute exacerbations$231,750
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Paul Foster, Professor Rakesh Kumar
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$231,75020072009
GNo:G0187409

Differential regulation of human mast cell degranulation by discrete forms of protein phosphatase 2A$50,000
Funding Body: Asthma Foundation of New South Wales

Project Team
Professor Alistair Sim, Doctor Nikki Verrills, Professor Paul Foster, Conjoint Associate Professor Peter Wark, Conjoint Professor Peter Gibson, Dr Gregory Kranias
SchemeRole
Research GrantInvestigator
Total AmountFunding StartFunding Finish
$50,00020072007
GNo:G0187247

Nitric Oxide Monitoring System (NIOX)$45,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor Peter Gibson, Conjoint Associate Professor Vicki Clifton, Conjoint Professor Warwick Giles, Emeritus Professor Michael Hensley, Doctor Vanessa Murphy, Conjoint Associate Professor Peter Wark, Doctor Vanessa McDonald, Associate Professor Jodie Simpson, Conjoint Associate Professor Bruce Whitehead, Professor Paul Foster, Professor Phil Hansbro, Associate Professor Lisa Wood
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$45,00020072007
GNo:G0188193

Class II biohazard containment hood and carbon dioxide cell culture incubator$20,000
Funding Body: NHMRC (National Health & Medical Research Council)

Elucidation of the association between Haemophilus influenzae infection and neutrophilic asthma.$20,000
Funding Body: Hunter Medical Research Institute

Project Team
Professor Phil Hansbro, Associate Professor Jodie Simpson, Professor Paul Foster, Conjoint Professor Margaret Dunkley
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$20,00020072007
GNo:G0187206

Hewlett Packard 7890 series gas chromatograph with accessories$20,000
Funding Body: NHMRC (National Health & Medical Research Council)

The role of tumstatin in angiogenesis and asthma$20,000
Funding Body: Hunter Medical Research Institute

Project Team
Professor Paul Foster, Doctor Nicole Hansbro, Doctor Simon Phipps, Professor Phil Hansbro
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$20,00020072007
GNo:G0187238

The prevention and treatment of Asthma with a diet high in seafood content$15,525
Funding Body: Seafood Services Australia

Project Team
Professor Phil Hansbro, Professor Paul Foster
SchemeRole
Seafood Industry Development FundInvestigator
Total AmountFunding StartFunding Finish
$15,52520072007
GNo:G0185404

2006 (8 grants)

PRC Priority Research Centre for Asthma & Respiratory Diseases$524,282
Funding Body: University of Newcastle

Project Team
Professor Paul Foster, Conjoint Professor Peter Gibson, Conjoint Professor Kenneth Beagley, Emeritus Professor Michael Hensley, Professor Phil Hansbro, Professor Joerg Mattes, Professor Alistair Sim, Conjoint Associate Professor Peter Wark
SchemeRole
Priority Research CentreChief Investigator
Total AmountFunding StartFunding Finish
$524,28220062013
GNo:G0186914

Surveillance and Analysis of Avian Influenza Viruses in Migratory Birds in Australia$249,625
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Phil Hansbro, Dr Ian Barr, Conjoint Associate Professor Peter Wark, Dr Paul Selleck, Dr Simone Warner, Professor Paul Foster, Dr Aeron Hurt, Dr Irene Peroulis, Dr John Curran, Conjoint Professor Peter Gibson
SchemeRole
Potential Avian Influenza-Induced PandemicInvestigator
Total AmountFunding StartFunding Finish
$249,62520062006
GNo:G0186000

Targeting protein phosphatases to control mast cell activation$50,000
Funding Body: Asthma Foundation of New South Wales

Project Team
Professor Alistair Sim, Professor Paul Foster
SchemeRole
Research GrantInvestigator
Total AmountFunding StartFunding Finish
$50,00020062006
GNo:G0186027

CD4+T-cell programming in early life and neonatal infection.$25,000
Funding Body: GlaxoSmithKline Australia

Project Team
Professor Paul Foster, Ms Angela Ferguson
SchemeRole
Support GrantChief Investigator
Total AmountFunding StartFunding Finish
$25,00020062007
GNo:G0186837

Identification of early-life signals induced in response to infection that predispose to asthma in later life$20,000
Funding Body: University of Newcastle

Project Team
Professor Phil Hansbro, Professor Paul Foster, Conjoint Professor Kenneth Beagley, Professor Alistair Sim
SchemeRole
Pilot GrantInvestigator
Total AmountFunding StartFunding Finish
$20,00020062006
GNo:G0186699

CD4 T Cell Programming by early life and neonatal infection$18,837
Funding Body: Asthma Foundation of New South Wales

Project Team
Ms Angela Ferguson, Professor Paul Foster
SchemeRole
PhD ScholarshipsInvestigator
Total AmountFunding StartFunding Finish
$18,83720062006
GNo:G0186002

Role of TRAIL on development of atopic dermatitis and T helper type 2 immunity$16,000
Funding Body: Hunter Medical Research Institute

Project Team
Professor Joerg Mattes, Professor Paul Foster
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$16,00020062006
GNo:G0186098

CRC for asthma - shared with Monash University$15,000
Funding Body: CRC for Asthma

Project Team
Professor Paul Foster
SchemeRole
Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$15,00020062006
GNo:G0186654

2005 (7 grants)

Drug targets from new animal models$2,030,948
Funding Body: CRC for Asthma

Project Team
Professor Paul Foster, Professor Phil Hansbro, Professor Joerg Mattes, Doctor Ming Yang, Dr Simon Phipps
SchemeRole
Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,030,94820052011
GNo:G0185860

CD4 T cell programming by neonatal and early-life infection$250,000
Funding Body: ARC (Australian Research Council)

Project Team
Professor Paul Foster, Conjoint Professor Kenneth Beagley, Professor Phil Hansbro
SchemeRole
Discovery ProjectsChief Investigator
Total AmountFunding StartFunding Finish
$250,00020052007
GNo:G0184398

High throughput proteomics - Thermo Finnigan ProteomeX LCQ Integrated Proteomicis Workstation$207,189
Funding Body: ARC (Australian Research Council)

Modulation of inflammatory responses in the asthmatic lung by Chlamydial infection$50,000
Funding Body: Asthma Foundation of New South Wales

Project Team
Professor Phil Hansbro, Professor Paul Foster, Conjoint Professor Kenneth Beagley
SchemeRole
Research GrantInvestigator
Total AmountFunding StartFunding Finish
$50,00020052005
GNo:G0185208

SealSafe Shelving Module IVC System & Slimline AHU Air Control Mobile Trolley$41,449
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Paul Foster
SchemeRole
Equipment GrantChief Investigator
Total AmountFunding StartFunding Finish
$41,44920052005
GNo:G0185470

Chlamydia infection of dendritic cells drives the development of pro-asthmatic Th2 cells$15,000
Funding Body: Hunter Medical Research Institute

Project Team
Conjoint Professor Kenneth Beagley, Professor Paul Foster
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$15,00020052005
GNo:G0184898

Prevention of asthma by immunisation with pneumococcal cell walls$10,000
Funding Body: University of Newcastle

Project Team
Professor Phil Hansbro, Professor Paul Foster, Conjoint Professor Kenneth Beagley, Conjoint Professor Peter Gibson
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$10,00020052005
GNo:G0184712

2004 (6 grants)

Molecular Mechanisms in the Regulation of allergy and inflammation$663,608
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Paul Foster, Dr Simon Hogan, Assoc. Prof Klaus Matthaei, Professor Philip Thompson, Professor Ian Young
SchemeRole
Program GrantChief Investigator
Total AmountFunding StartFunding Finish
$663,60820042007
GNo:G0184188

Cytokines regulating airway inflammation, remodelling and hyper-reactivity in chronic asthma$110,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Paul Foster, Professor Rakesh Kumar, Dr Mark Raftery
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$110,00020042006
GNo:G0184155

Modulation of Asthma by bacterial infection or vaccination in different age groups$60,000
Funding Body: Rebecca L Cooper Medical Research Foundation Ltd

Project Team
Professor Phil Hansbro, Professor Paul Foster, Conjoint Professor Kenneth Beagley
SchemeRole
Research GrantInvestigator
Total AmountFunding StartFunding Finish
$60,00020042006
GNo:G0184154

Investigation of the role of eosinophils in regulating disease processes in asthma$15,000
Funding Body: University of Newcastle

Project Team
Professor Paul Foster
SchemeRole
New Staff GrantChief Investigator
Total AmountFunding StartFunding Finish
$15,00020042004
GNo:G0184841

Modulation of immune responses in asthma by bacterial infections during early life.$15,000
Funding Body: University of Newcastle

Project Team
Professor Phil Hansbro, Professor Paul Foster, Conjoint Professor Peter Gibson
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$15,00020042004
GNo:G0183512

Chemokine-mediated enhancement of transcutaneous immunization to target genital and respiratory tract chlamydial infections$10,000
Funding Body: University of Newcastle

Project Team
Conjoint Professor Kenneth Beagley, Professor Paul Foster
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$10,00020042004
GNo:G0183467
Edit

Research Supervision

Number of current supervisions24
Total current UoN Masters EFTSL0.1
Total current UoN PhD EFTSL5.05

For supervisions undertaken at an institution other that the University of Newcastle, details are shown in italics, and the institution name is listed below the program name.

Current Supervision

CommencedProposed
Completion
ProgramSupervisor TypeResearch Title
20132015M Philosophy (Immun & Microbi)Co-SupervisorRole of Innate Immune Cells in the Pathogenesis of COPD
20132017PhD (Immunology & Microbiol)Co-SupervisorCharacterisation of Novel Molecular Cell Signalling Pathways that Regulate Host Immune Defence in Infection-Induced Allergic Airway Disease
20132017PhD (Paediatrics)Co-SupervisorThe Role of MicroRNAs in Response to Rhinovirus Infection in Allergic Airways Disease
20132017PhD (Immunology & Microbiol)Co-SupervisorImproved Prevention or Treatment Strategies for Steroid-Resistant Asthma
20122016PhD (Immunology & Microbiol)Co-SupervisorInvestigation of MicroRNAs, Epigenetic Changes and other Factors in the Development and Progression of Lung Cancer
20122016PhD (Immunology & Microbiol)Co-SupervisorThe Role of Rhinovirus, TRAIL, IL-13 and PP2A in Allergic Airways Disease
20122016PhD (Immunology & Microbiol)Co-SupervisorUnderstanding the mechanisms of airway hyper-responsiveness in a mouse model of asthma
20122016PhD (Immunology & Microbiol)Co-SupervisorRoles of Bromodomain and extra terminal (BET) proteins in Suppression of Airway Inflammation
20122016PhD (Immunology & Microbiol)Co-SupervisorAssessing the Epigenetic Involvement in the Development and Progression of Chronic Obstructive Pulmonary Disease (COPD)
20122016PhD (Paediatrics)Co-SupervisorRole of miRNAs in Early Life Viral Infections and the Development of Asthma in Later Life
20112015PhD (Immunology & Microbiol)Co-SupervisorMechanisms of Predisposition to Secondary Bacterial Pneumonia
20112015PhD (Immunology & Microbiol)Co-SupervisorThe Role of Interferon Epsilon in Protection Against Chlamydial Reproductive Tract Infections
20112015PhD (Immunology & Microbiol)Co-SupervisorThe Roles of Fibulin-1 in Airway Remodelling in Lung Diseases
20112015PhD (Immunology & Microbiol)Co-SupervisorThe Role of Innate Cells in Infectious Exacerbation of COPD
20112015PhD (Immunology & Microbiol)Co-SupervisorInvestigation of Pathogenesis of Chronic Obstructive Pulmonary Disease (COPD)
20112015PhD (Immunology & Microbiol)Co-SupervisorImmunoregulatory Therapies for Inflammatory Diseases
20102014PhD (Immunology & Microbiol)Co-SupervisorRespiratory Innate Immune Factors Regulate Steroid-Resistant Airway Hyperactivity and Asthma
20102015PhD (Immunology & Microbiol)Co-SupervisorIndentification of New Therapeutics in COPD/ Emphysema
20102014PhD (Immunology & Microbiol)Co-SupervisorRole of TRAIL and TLRT in Response to Rhinovirus Infection in Allergic Airways Disease
20092013PhD (Immunology & Microbiol)Principal SupervisorThe Role of MicroRNA in Regulating Anti-Bacterial Responses in Innate Immune Cells
20092013PhD (Immunology & Microbiol)Co-SupervisorElucidation the Pathogenesis of Influenza Infection in Chronic Airway Diseases
20082012PhD (Immunology & Microbiol)Co-SupervisorChlamydia and Asthma
20082012PhD (Immunology & Microbiol)Principal SupervisorThe Role of miRNAs in Allergic Airways Disease and T Cell Biology
20072011PhD (Immunology & Microbiol)Co-SupervisorIdentification of Early Life Signs Induced in Response to Infection that Predispose to Allergic Airways Disease in Later Life

Past Supervision

YearProgramSupervisor TypeResearch Title
2013PhD (Immunology & Microbiol)Principal SupervisorThe Role of Early Life Infection on the Programming of CD4+ T-cells
2012PhD (Immunology & Microbiol)Co-SupervisorModulation of Responses in Allergic Airways Disease by Haemophilus Influenzae Infection
2012PhD (Immunology & Microbiol)Co-SupervisorNovel Therapeutic Approaches for the Treatment of Allergic Airways Disease
2011PhD (Immunology & Microbiol)Principal SupervisorUnderstanding the Inflammatory Mechanisms That Predispose to Emphysema in Mouse Models
2011PhD (Immunology & Microbiol)Principal SupervisorImmune Mechanisms that Promote the Development of Inducible Bronchus-Associated Lymphoid Tissue (IBALT)
2011PhD (Immunology & Microbiol)Principal SupervisorThe Innate Immune Mechanisms Underlying the Interplay Between Respiratory Infections and Asthma
2009PhD (Immunology & Microbiol)Principal SupervisorNutritional Modulation of Lung Inflammation
2008PhD (Immunology & Microbiol)Co-SupervisorModulation of Responses in the Asthmatic Lung by Chlamydial Infection
2007PhD (Immunology & Microbiol)Co-SupervisorModulation of Responses in the Asthmatic Lung by Streptococcus Pneumoniae
Edit

Professor Paul Foster

Work Phone(02) 4042 0163
Fax(02) 4042 0036
Email
PositionLaureate Professor
School of Biomedical Sciences and Pharmacy
Faculty of Health and Medicine
The University of Newcastle, Australia
Focus AreaImmunology and Microbiology
Office
2401 HMRI,
HMRI,
Other
URL:www.newcastle.edu.au/profile/paul-foster