Profile Image

Associate Professor Michael Bowyer

Associate Professor

School of Environmental and Life Sciences (Chemistry)

Career Summary

Biography

From 1995 until present MB has been the sole chemist forming part of a multi-disciplinary academic group (known as the Discipline of Applied Sciences) based at the Ourimbah campus of the University of Newcastle. The campus has research specialisations in Food Technology, Human Nutrition, Sport Sciences & Marine Science. Opportunities for MB to develop an independent research profile in his field of training (synthetic organic chemistry) have been limited, however, he has successfully collaborated with a number of research groups with in the University of Newcastle (please see"Research Interests" for details. This work has seen the successful completion of 5 research higher degree students (PhD) and numerous Honours students. MB is the author of some 30 publications across a range research areas in high impact peer reviewed journals. In addition to maintaining an active research profile, MB has assumed a significant administrative role in the School of Environmental & Life Sciences since becoming Head of Discipline of Applied Sciences in 2006. Duties include day to day management of budget and staffing issues within the Discipline and participation in numerous committees and working parties at University, Faculty and School level. MB has also represented the Faculty internationally in the negotiation of academic twinning agreements with overseas tertiary institutions.

Research Expertise

MB trained as a research chemist with expertise in organic synthesis. He has a particular interest in how interactions between organic molecules act as signalling agents in both natural and synthetic systems. MB has established successful collaborative research with Emeritus Professor Ron Wills (Food Science & Human Nutrition - Newcastle University) to develop new, environmentally friendly treatments for extending the postharvest life of fresh farm produce using nitric oxide (NO) gas to delay senescence without refrigeration. While the role of NO in mammalian physiology is relatively well understood, its action in plants remains largely undefined. MB has utilised his skills as an organic chemist to synthesise zwitterionic NO donor compounds capable of delivering a precise quantity of NO gas in a controlled manner. Solid phase NO delivery has enhanced the scope and flexibility of NO fumigation technology by eliminating the need for cumbersome and expensive infrastructure (e.g. cylinders and regulators). The research has to date yielded 4 refereed journal articles (3 published, 1 submitted) and competitive grant funding of $26.5K. Work in this field has recently been extended to investigate the potential use of NO donor technology to control settlement behaviour in marine organisms. MB has co-supervised two PhD students (1 completed) and 2 Honours student (1 completed) in this field. MB has been involved in molecular imprinting research with Associate Professor Adam McCluskey since 1999 and Dr Clovia Holdsworth since 2002. Initial research (99-01, $92000) supported by the Grape & Wine Research & Development Corporation (GWRDC) focused on the successful development of MIPs for the selective sensing of chloroarene contaminants in wine. These findings were reported in two peer-reviewed articles (Aust. J. Chem, 2004, 57, 759; Aust. J. Chem, 2006, 59, 129) and at domestic and international conferences including the World Congress on Synthetic Receptors (Lisbon, Portugal, October 13-15, 2003). MBs current research is supported by separate ARC Linkage Grants. Work conducted in conjunction with the Australian Federal Police ($190,000 & $51,000 industry component) seeks to develop novel MIP-based sensors for the selective identification of a number of illicit substances. Computational modelling protocols have been developed to improve MIP formulation and selectivity by pre-screening target molecules against a library of commercial functional monomers to identify and rank favourable interactions. These important outcomes were reported in 2005 (Aust. J. Chem, 2005, 58, 315). Attention is currently focused on the preparation of MIP-based films for incorporation into a portable FTIR spectrophotometers to enable the assessment of crime scenes to be undertaken in-field in real time. Work with the Bureau of Sugar Research Stations ($171,336 & $45,000 industry component) aims to develop transitional metal-mediated MIPs capable of sequestering amino acids contaminants associated with the non-enzymatic browning of processed sugar. MIPs targeting high value, biologically active flavonoids are also being investigated to improve the competitiveness of the Australian sugar industry. MB has co-supervised five PhD students and 4 Honours students in the field of MIP research.

Teaching Expertise
As a foundation academic in the School of Applied Sciences, MB has been solely responsible for development, delivery assessment and administration of all chemistry courses taught at the University of Newcastles Ourimbah Campus. In a decade of service, MB has overseen an expansion in First Year Chemistry from an initial student intake of 7 students (1995) to enrolment numbers exceeding 140 students in 2007. MB currently undertakes all lecturing and tutoring teaching for the two 1000 level chemistry courses (CHEM1110 & CHEM1120) offered at Ourimbah. The courses are designed to provide an introduction to general & bioorganic chemistry for Life Science undergraduates. The face to face commitment is approximately 150 hours p.a. MB has also made teaching contributions to 2000 & 3000 level courses in the fields of environmental (CHEM2260, CHEM3260) and organic chemistry (CHEM2330, 33330) at the Ourimbah and Callaghan campuses of the University of Newcastle. Specialist 4000 level courses covering selected areas of heterocyclic synthesis have also been prepared. and delivered as part of the Discipline of Chemistrys Honours program at Callaghan. MB has fully embraced the use of modern teaching methods to delivery quality outcomes for students. Approaches utilised include: " Provision of comprehensive guidelines of all course content to ensure that students have a full understanding of the expected course outcomes and how those outcomes will be achieved. " Use of Blackboard as the main tool for the provision of course information to students. " Extensive use multimedia-based teaching methods to explain and enhance teaching in lectures and laboratories.

Administrative Expertise
MB has fulfilled a variety of administrative roles within the School of Environmental and Life Sciences of the University of Newcastle. Activities undertaken include: School Administration School of Applied Science (SAS) Timetable Coordinator (1995-1999): Responsibility for scheduling of UG courses (~50) taught by the SAS. Responsibilities included liasing with Callaghan-based staff to ensure timetable compatibility between campuses to allow for inter-campus teaching, and participation in workshops with other stakeholders at the Ourimbah campus to prioritise room allocations for classes. Honours Coordinator (SAS) (2001-2006): Responsibilities included vetting and approval of new candidates, preparation and distribution of assignment work, organization of seminar times, maintenance of Blackboard site, authoring of Honours handbook and selection of markers and committee members for thesis marking. Head of Discipline - Applied Sciences (2007- present): Responsibilities include; allocation of teaching load for FT staff, planning & maintenance of PT teaching budget, contracting of PT staff. School Working Party - redevelopment of B. Env. Sci. (2009-2010): Overseeing implementation of recommendations relating to B . Env. Sci. program. Coordinator - HSC Experimentfest (2004 - present). Planning and execution of Experimentfest operations at Ourimbah. Campus Administration " SAS Teaching Equipment Committee Representative (1996-1999). The committee was formed to manage & resource campus teaching space (e.g. projection facilities, internet). " Campus Computer Committee Representative (1996-1998). Formed to develop common policy with TAFE regarding computer hardware and software specifications for the Ourimbah campus. " Campus Policy Committee Alcohol Consumption (1997-1998). Formed to formulate a workable alcohol policy for a multi-sectorial campus. Faculty Administration " School Representative Faculty Quality Assurance Committee (2002-2003). Responsibilities included fortnightly attendance at meetings, collection and compilation of school-based data of relevance to the committee as directed by the Committee Chair. Faculty Representative Open Foundation External review committee (2005).

Collaborations
MB has a particular interest in how interactions between organic molecules act as signalling agents in both natural and synthetic systems. MB has established a successful collaborative research program with Emeritus Professor Ron Wills (Food Technology - Newcastle University) to develop new, environmentally friendly treatments for extending the postharvest life of selected farm produce using nitric oxide (NO) gas to delay senescence without the need for refrigeration. While the role of NO as a signalling agent in mammalian physiology is relatively well understood, its action in plants remains largely undefined. MB has utilised his skills as an organic chemist to synthesise a range of water soluble, zwitterionic NO donor compounds capable of delivering a known quantity of NO gas to produce in a controlled manner. Solid phase delivery of NO gas enhances the scope and flexibility of NO fumigation technology by eliminating the need for cumbersome and expensive infrastructure (e.g. cylinders and regulators). The research has to date yielded 4 refereed journal articles and competitive grant funding of $26.5K. MB has co-supervised two PhD completions and 1 Honours student associated with this work. MB has been extensively involved in molecular imprinting (MIP) research with Professor Adam McCluskey since 1999 and Dr Clovia Holdsworth since 2002. Initial research (99-01, $92000) supported by the Grape & Wine Research & Development Corporation (GWRDC) focused on the successful development of MIPs for the selective sensing of chloroarene contaminants in wine. These findings were reported in two peer-reviewed articles (Aust. J. Chem, 2004, 57, 759; Aust. J. Chem, 2006, 59, 129) and at domestic and international conferences including MIP2000 - The First Workshop on Molecular Imprinting, and Synthetic Receptors 2003 - The First World Congress on Synthetic Receptors (Lisbon, Portugal, October 13-15, 2003). MBs current research is supported by separate ARC Linkage Grants. Work conducted in conjunction with the Australian Federal Police ($190,000 & $51,000 industry component) seeks to develop novel MIP-based sensors for the selective identification of a number of illicit substances. Computational modelling protocols have been developed to improve MIP formulation and selectivity by pre-screening target molecules against a library of commercial functional monomers to identify and rank favourable interactions. These important outcomes were reported in 2005 (Aust. J. Chem, 2005, 58, 315). Attention is currently focused on the preparation of MIP-based films for the detection of narcotics and explosives using portable FTIR spectrophotometers for rapid, in-field assessment of suspected crime scenes. MB has successfully supervised 5 PhD completions and 7 Honours students. He currently co-supervises 4 RHD candidates.

Qualifications

  • PhD, University of New South Wales
  • Diploma in Education, University of New South Wales
  • Bachelor of Science (Honours), University of New South Wales

Keywords

  • General Chemistry
  • Heterocyclic Chemistry
  • Molecularly Imprinted Polymers
  • Nitric oxide releaseing agents
  • Organic Chemistry

Fields of Research

Code Description Percentage
030399 Macromolecular and Materials Chemistry not elsewhere classified 60
030499 Medicinal and Biomolecular Chemistry not elsewhere classified 25
090899 Food Sciences not elsewhere classified 15

Professional Experience

UON Appointment

Title Organisation / Department
Associate Professor University of Newcastle
School of Environmental and Life Sciences
Australia

Academic appointment

Dates Title Organisation / Department
1/01/2005 -  Lecturer University of Newcastle
School of Environmental and Life Sciences
Australia
1/01/1998 - 1/12/2005 Lecturer University of Newcastle
School of Environmental and Life Sciences
Australia
1/01/1995 - 1/12/1997 Lecturer University of Newcastle
School of Environmental and Life Sciences
Australia
1/01/1988 - 1/12/1992 Academic The University of New South Wales
Australia

Awards

Recognition

Year Award
1999 Dean's Award for Teaching Excellence - School of Science & Technology
University of Newcastle
Edit

Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Chapter (2 outputs)

Year Citation Altmetrics Link
2015 Bowyer MC, McCluskey A, Scarlett CJ, Vuong QV, 'Pancreatic Cancer drugs: Case Studies in Synthesis and Production', Plant Bioactive Compounds for Pancreatic Cancer Prevention and Treatment, Nova Science Publishers, New York 145-193 (2015) [B1]
Co-authors C Scarlett, Vanquan Vuong, Adam Mccluskey
2011 Booker KM, Holdsworth CI, Bowyer MC, McCluskey A, 'Ionic liquids as porogens in the synthesis of molecularly imprinted polymers', Applications of Ionic Liquids in Science and Technology, Intech, Croatia 197-212 (2011) [B1]
DOI 10.5772/21725
Co-authors Adam Mccluskey, Clovia Holdsworth

Journal article (50 outputs)

Year Citation Altmetrics Link
2016 Chuen TLK, Vuong QV, Hirun S, Bowyer MB, Predebon MJ, Goldsmith CD, et al., 'Antioxidant and anti-proliferative properties of Davidson¿s plum (Davidsonia pruriens F. Muell) phenolic-enriched extracts as affected by different extraction solvents', Journal of Herbal Medicine, (2016)
DOI 10.1016/j.hermed.2016.08.005
Co-authors Vanquan Vuong, Jennette Sakoff, C Scarlett
2016 Nguyen VT, Bowyer MC, Van Altena IA, Scarlett CJ, 'Optimisation of microwave-assisted extraction from Phyllanthus amarus for phenolic compounds-enriched extracts and antioxidant capacity', Chemical Papers, 70 i-xiii (2016)

© 2016 Institute of Chemistry, Slovak Academy of Sciences.Phyllanthus amarus is known as a healing herb which has traditionally been used in the treatment of various diseases suc... [more]

© 2016 Institute of Chemistry, Slovak Academy of Sciences.Phyllanthus amarus is known as a healing herb which has traditionally been used in the treatment of various diseases such as hepatitis, diabetes and cancer. The extraction parameters have great effects on the extraction efficiency of bioactive compounds and pharmacological activity of the extracts. This study sought to optimise the microwave-assisted extraction parameters for phenolic compounds-enriched extracts and antioxidant capacity from P. amarus using response surface methodology (RSM). The results showed that the optimal microwave-assisted extraction parameters were an extraction time of 30 min, an irradiation time of 14 s min-1 and a ratio of solvent to sample of 150 mL g-1. The total phenolic content, phenolic extraction efficiency, saponin content, 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) (ABTS) radical scavenging capacity, 2,2-diphenyl-1-picryl-hydrazil (DPPH) radical scavenging capacity and ferric reducing antioxidant power of the P. amarus achieved under these optimal parameters were 87.3 mg of gallic acid equivalents (GAE) per gram of dried sample, 69.7 %, 134.9 mg of escin equivalents (EE) per gram of dried sample, 997.8, 604.7 and 437.3 all in mg of trolox equivalents (TE) per gram of dried sample, respectively, which were not significantly different from the predicted values (86.9 mg of GAE per gram of dried sample, 67.3 %, 123.5 mg of EE per gram of dried sample, 1013.3 mg of TE per gram of dried sample, 530.6 mg of TE per gram of dried sample and 423.5 mg of TE per gram of dried sample, respectively). Accordingly, the optimal microwave-assisted extraction parameters of 30 min, 14 s min-1 and 150 mL g-1 are recommended for the extraction of enriched phenolics from P. amarus for potential application in the nutraceutical and pharmaceutical industries.

DOI 10.1515/chempap-2016-0009
Co-authors C Scarlett
2016 Nguyen VT, Pham NMQ, Vuong QV, Bowyer MC, van Altena IA, Scarlett CJ, 'Phytochemical retention and antioxidant capacity of xao tam phan (Paramignya trimera) root as prepared by different drying methods', Drying Technology, 34 324-334 (2016) [C1]

© 2016, Taylor & Francis Group, LLC.Xao tam phan (Paramignya trimera (Oliv.) Guillaum) has been used as an herbal medicine for the treatment of cancer or cancer-like diseases in ... [more]

© 2016, Taylor & Francis Group, LLC.Xao tam phan (Paramignya trimera (Oliv.) Guillaum) has been used as an herbal medicine for the treatment of cancer or cancer-like diseases in recent years, particularly in Vietnam. Drying is an important step for preparation of dried materials for storage and further investigation; however, the effects of drying must be taken into account when processing samples, because this can have profound effects on the stability of phytochemical compounds and the biological activity of the dried P. trimera root. As such, this study assessed the effects of four different drying methods (conventional, hot air, vacuum, and microwave) on phytochemical retention and antioxidant capacity of P. trimera root, to identify an optimal drying method for P. trimera root. The results showed that the drying methods significantly affected phytochemical levels and antioxidant capacity of P. trimera root and that among the four drying methods tested, microwave drying (400¿W) had the highest levels of phytochemical compounds, with total phenolic, total flavonoid, proanthocyanidin, and saponin contents of 11.27¿mg GAE, 19.88¿mg RE, 3.98¿mg CE, and 267.15¿mg EE/gram of dried sample, respectively. Dried sample prepared using this method had antioxidant capacity comparable to that of other drying methods. In addition, this method had the shortest drying time (0.28¿h) and consumed the least energy (0.28¿kWh). Therefore, microwave drying should be considered for drying P. trimera root for further investigation and utilization.

DOI 10.1080/07373937.2015.1053566
Citations Web of Science - 1
Co-authors C Scarlett, Vanquan Vuong
2016 Bhuyan DJ, Vuong QV, Chalmers AC, Van Altena IA, Bowyer MC, Scarlett CJ, 'Investigation of phytochemicals and antioxidant capacity of selected Eucalyptus species using conventional extraction', Chemical Papers, 70 567-575 (2016)

© 2015 Institute of Chemistry, Slovak Academy of Sciences.Eucalyptus species have found their place in traditional medicine and pharmacological research and they have also been s... [more]

© 2015 Institute of Chemistry, Slovak Academy of Sciences.Eucalyptus species have found their place in traditional medicine and pharmacological research and they have also been shown to possess a large number of phenolic compounds and antioxidants. The present study sought to implement conventional extraction to yield maximal total phenolic content (TPC), total flavonoid content (TFC), proanthocyanidins, antioxidants, and saponins from E. robusta using different solvents. The most suitable extraction solvent was further employed for extracting phytochemicals from E. saligna, E. microcorys, and E. globulus to select the Eucalyptus species with the greatest bioactive compound content. The results emphasised the efficiency of water in extracting TPC ((150.60 ± 2.47) mg of gallic acid equivalents per g), TFC ((38.83 ± 0.23) mg of rutin equivalents per g), proanthocyanidins ((5.14 ± 0.77) mg of catechin equivalents per g), and antioxidants ABTS ((525.67 ± 1.99) mg of trolox equivalents (TE) per g), DPPH ((378.61 ± 4.72) mg of TE per g); CUPRAC ((607.43 ± 6.69) mg of TE per g) from E. robusta. Moreover, the aqueous extract of E. robusta had the highest TPC, TFC and antioxidant values among the other Eucalyptus species tested. These findings highlighted the efficiency of conventional extraction in extracting natural bioactive compounds from Eucalyptus species for pharmaceutical and nutraceutical applications.

DOI 10.1515/chempap-2015-0237
Co-authors Vanquan Vuong, C Scarlett, Anita Chalmers
2016 Nguyen VT, Pham HNT, Bowyer MC, Van Altena IA, Scarlett CJ, 'Influence of solvents and novel extraction methods on bioactive compounds and antioxidant capacity of Phyllanthus amarus', Chemical Papers, 70 556-566 (2016)

© 2015 Institute of Chemistry, Slovak Academy of Sciences.Phyllanthus amarus (P. amarus) is a herbal plant used in the treatment of various diseases such as hepatitis, diabetes, ... [more]

© 2015 Institute of Chemistry, Slovak Academy of Sciences.Phyllanthus amarus (P. amarus) is a herbal plant used in the treatment of various diseases such as hepatitis, diabetes, and cancer. Efficiency of its bioactive compounds extraction and therefore the biological activity of the extracts are significantly influenced by both solvent character and extraction method. This study is aimed at the determination of the influence of six various solvents (water, acetonitrile, ethanol, methanol, ethyl acetate, and dichloromethane) and nine different extraction methods (conventional, ultrasound-assisted, microwave-assisted, and six novel methods) on the extraction efficiency and antioxidant capacity of P. amarus. The results indicated that water extracted the maximal amount of phenolics from P. amarus and had the highest antioxidant capacity, while microwave-assisted extraction provided the highest yields of phenolics and saponins, and the highest antioxidant capacity with the lowest energy consumption when compared to the other extraction methods. These findings implied that water and microwave-assisted extraction are recommended as the most effective solvent and method for the extraction of bioactive compounds from P. amarus for potential application in the pharmaceutical and nutraceutical industries.

DOI 10.1515/chempap-2015-0240
Co-authors C Scarlett
2016 Papoutsis K, Pristijono P, Golding JB, Stathopoulos CE, Bowyer MC, Scarlett CJ, Vuong QV, 'Optimisation of aqueous extraction conditions for the recovery of phenolic compounds and antioxidants from lemon pomace', International Journal of Food Science and Technology, 51 2009-2018 (2016)

© 2016 Institute of Food Science and TechnologyThe aim of this study was to optimise the aqueous extraction conditions for the recovery of phenolic compounds and antioxidant capa... [more]

© 2016 Institute of Food Science and TechnologyThe aim of this study was to optimise the aqueous extraction conditions for the recovery of phenolic compounds and antioxidant capacity of lemon pomace using response surface methodology. An experiment based on Box¿Behnken design was conducted to analyse the effects of temperature, time and sample-to-water ratio on the extraction of total phenolic compounds, total flavonoids, proanthocyanidins and antioxidant capacity. Sample-to-solvent ratio had a negative effect on all the dependent variables, while extraction temperature and time had a positive effect only on TPC yields and ABTS antioxidant capacity. The optimal extraction conditions were 95¿°C, 15¿min and a sample-to-solvent ratio of 1:100¿g¿mL-1. Under these conditions, the aqueous extracts had the same content of TPC and TF as well as antioxidant capacity in comparison with those of methanol extracts obtained by sonication. Therefore, these conditions could be applied for further extraction and isolation of phenolic compounds from lemon pomace.

DOI 10.1111/ijfs.13168
Co-authors C Scarlett, Vanquan Vuong
2016 Dang TT, Vuong QV, Schreider MJ, Bowyer MC, Van Altena IA, Scarlett CJ, 'The Effects of Drying on Physico-Chemical Properties and Antioxidant Capacity of the Brown Alga (Hormosira banksii (Turner) Decaisne)', Journal of Food Processing and Preservation, (2016)
DOI 10.1111/jfpp.13025
Co-authors C Scarlett, Maria Schreider, Vanquan Vuong
2016 Thuy Pham HN, Nguyen VT, Vuong QV, Bowyer MC, Scarlett CJ, 'Bioactive compound yield and antioxidant capacity of Helicteres hirsuta Lour. stem as affected by various solvents and drying methods', Journal of Food Processing and Preservation, (2016)
DOI 10.1111/jfpp.12879
Co-authors Vanquan Vuong, C Scarlett
2016 Papoutsis K, Vuong QV, Pristijono P, Golding JB, Bowyer MC, Scarlett C, Stathopoulos CS, 'Enhancing the Total Phenolic Content and Antioxidants of Lemon Pomace Aqueous Extracts by Applying UV-C Irradiation to the Dried Powder', Foods, 5 (2016)
DOI 10.3390/foods5030055
Co-authors C Scarlett, Vanquan Vuong
2015 Vuong QV, Hirun S, Chuen TLK, Goldsmith CD, Murchie S, Bowyer MC, et al., 'Antioxidant and anticancer capacity of saponin-enriched Carica papaya leaf extracts', International Journal of Food Science and Technology, 50 169-177 (2015) [C1]

© 2014 Institute of Food Science and Technology.Summary: The papaya (Carica papaya) leaf (PL) contains high levels of saponins and polyphenolic compounds, and historically, it ha... [more]

© 2014 Institute of Food Science and Technology.Summary: The papaya (Carica papaya) leaf (PL) contains high levels of saponins and polyphenolic compounds, and historically, it has been used as a folk medicine for numerous ailments, including cancer. PL is traditionally prepared by hot water extraction; however, optimised extraction conditions have not been assessed. This study optimised conditions for the extraction of saponins from PL and assessed their antioxidant capacity and antipancreatic cancer activity. Optimisation was achieved using response surface methodology. Saponins and total phenolic compounds were assessed for their antioxidant, free radical scavenging, ion-reducing capacity, and antipancreatic cancer activity. Optimal aqueous extraction conditions were 85 °C, 25 min. and a water-to-leaf ratio of 20:1 mL g-1. Ethanol extracts demonstrated higher antioxidant, free radical scavenging and ion-reducing capacity, as well as antipancreatic cancer activity. This study revealed that the PL contains numerous bioactive compounds, with significant anticancer activity warranting further studies on the isolation and characterisation of individual bioactive compounds from the PL.

DOI 10.1111/ijfs.12618
Citations Scopus - 1
Co-authors Vanquan Vuong, C Scarlett
2015 Vuong QV, Van TN, Dang TT, Bhuyan DJ, Goldsmith CD, Sadeqzadeh E, et al., 'Optimization of ultrasound-assisted extraction conditions for euphol from the medicinal plant, Euphorbia tirucalli, using response surface methodology', INDUSTRIAL CROPS AND PRODUCTS, 63 197-202 (2015) [C1]
DOI 10.1016/j.indcrop.2014.09.057
Citations Scopus - 3Web of Science - 2
Co-authors C Scarlett, Vanquan Vuong
2015 Nguyen VT, Bowyer MC, Vuong QV, Altena IAV, Scarlett CJ, 'Phytochemicals and antioxidant capacity of Xao tam phan (Paramignya trimera) root as affected by various solvents and extraction methods', Industrial Crops and Products, 67 192-200 (2015) [C1]

© 2015 Elsevier B.V.Xao tam phan (. Paramignya trimera (Oliv.) Guillaum) is a Vietnamese traditionally medicinal plant used in the treatment of numerous cancers. The preparation ... [more]

© 2015 Elsevier B.V.Xao tam phan (. Paramignya trimera (Oliv.) Guillaum) is a Vietnamese traditionally medicinal plant used in the treatment of numerous cancers. The preparation of Xao tam phan extracts including solvent type and extraction method have significant effects on extraction efficiency, phytochemical profile and biological activity. This study aimed to investigate the effects of five various solvents (water, acetonitrile, methanol, ethyl acetate and hexane) and three different extraction methods (conventional, ultrasound-assisted and microwave-assisted) on phytochemical yield and antioxidant capacity of P. trimera root from Vietnam. The results indicate that methanol extracted the maximal yield of phytochemicals from P. trimera and exhibited the greatest antioxidant capacity, with eleven compounds were identified and quantified. Microwave-assisted extraction produced the maximal phytochemical yields (except for total flavonoids) and antioxidant capacity, when compared to conventional and ultrasound-assisted extractions. These data reveal that the use of methanol and microwave-assisted extraction are recommended for extraction of biologically active phytochemicals from P. trimera root for application in the nutraceutical and/or pharmaceutical industries.

DOI 10.1016/j.indcrop.2015.01.051
Citations Scopus - 7Web of Science - 5
Co-authors C Scarlett, Vanquan Vuong
2015 Zayas HA, McCluskey A, Bowyer MC, Holdsworth CI, 'Potentiometric determination of acid dissociation constants of novel biaryl monomers', Analytical Methods, 7 8206-8211 (2015) [C1]

© 2015 The Royal Society of Chemistry.The acid dissociation constants (pK<inf>a</inf>s) of a number of novel polymerisable vinyl biaryl compounds, 4-(4'-ethenylphenyl)-pyridine (... [more]

© 2015 The Royal Society of Chemistry.The acid dissociation constants (pKas) of a number of novel polymerisable vinyl biaryl compounds, 4-(4'-ethenylphenyl)-pyridine (M1), 4'-ethenyl-(1,1'-biphenyl)-4-ol (M2), 4'-ethenyl-N,N-dimethyl-(1,1'-biphenyl)-3-amine (M3), 4'-ethenyl-(1,1'-biphenyl)-4-methanol (M4), 4'-ethenyl-N,N-dimethyl-(1,1'-biphenyl)-4-amine (M5), 4'-ethenyl-(1,1'-biphenyl)-4-carboxylic acid (M6), 4'-ethenyl-4-hydroxy-5-methyl-(1,1'-biphenyl)-3-carboxaldehyde (M7) were determined in a mixed solvent (THF-water) potentiometric titration at 25 °C and subsequent extrapolation to pure water via the Yasuda-Shedlovsky method. The acidity and basicity of the compounds in THF-water mixtures was observed to decrease with increasing THF fraction and is attributed to the corresponding decrease in the dielectric constant of the solution. To the best of our knowledge, this is the first reported study of pKa values undertaken for this class of compounds. The biaryls, M1-M7, were prepared by microwave-assisted Suzuki cross coupling of 4-vinylphenyl boronic acid with the appropriate aryl bromide and were custom designed for use as functional monomers in the synthesis of molecularly imprinted polymers.

DOI 10.1039/c5ay01673h
Co-authors Adam Mccluskey, Clovia Holdsworth
2015 Vuong QV, Hirun S, Chuen TLK, Goldsmith CD, Munro B, Bowyer MC, et al., 'Physicochemical, antioxidant and anti-cancer activity of a Eucalyptus robusta (Sm.) leaf aqueous extract', INDUSTRIAL CROPS AND PRODUCTS, 64 167-174 (2015) [C1]
DOI 10.1016/j.indcrop.2014.10.061
Citations Scopus - 3Web of Science - 3
Co-authors C Scarlett, Jennette Sakoff, Vanquan Vuong, Anita Chalmers
2015 Munro B, Vuong QV, Chalmers AC, Goldsmith CD, Bowyer MC, Scarlett CJ, 'Phytochemical, Antioxidant and Anti-Cancer Properties of Euphorbia tirucalli Methanolic and Aqueous Extracts.', Antioxidants, 4 647-661 (2015) [C1]
Co-authors Vanquan Vuong, C Scarlett, Anita Chalmers
2015 Bhuyan DJ, Quan VV, Chalmers AC, van Altena IA, Bowyer MC, Scarlett CJ, 'Microwave-assisted extraction of Eucalyptus robusta leaf for the optimal yield of total phenolic compounds', INDUSTRIAL CROPS AND PRODUCTS, 69 290-299 (2015) [C1]
DOI 10.1016/j.indcrop.2015.02.044
Citations Scopus - 8Web of Science - 6
Co-authors Vanquan Vuong, Anita Chalmers, C Scarlett
2015 Chuen TLK, Vuong QV, Hirun S, Bowyer MC, Goldsmith CD, Scarlett CJ, 'Optimum aqueous extraction conditions for preparation of a phenolic-enriched Davidson¿s plum (Davidsonia pruriens F. Muell) extract', International Journal of Food Science and Technology, 50 2475-2482 (2015) [C1]
DOI 10.1111/ijfs.12915
Citations Scopus - 1
Co-authors C Scarlett, Vanquan Vuong
2015 Vuong QV, Zammit N, Munro BR, Murchie S, Bowyer MC, Scarlett CJ, 'Effect of drying conditions on physicochemical and antioxidant properties of vitex agnus-castus leaves', Journal of Food Processing and Preservation, (2015) [C1]

© 2015 Wiley Periodicals, Inc. Vitex agnus-castus (VitexAC) leaves have been used for medicinal purposes for many years. Drying is important to prepare starting materials for fur... [more]

© 2015 Wiley Periodicals, Inc. Vitex agnus-castus (VitexAC) leaves have been used for medicinal purposes for many years. Drying is important to prepare starting materials for further processing, as it is associated with production cost and quality of the materials. Herein, the effects of five different drying conditions on the physical, chemical and antioxidant properties of VitexAC were evaluated. The results showed that 30% of dried leaves with moisture content of less than 7% could be produced from fresh leaves. VitexAC leaves dried by freeze and vacuum drying at 65C had higher levels of bioactive compounds as well as higher antioxidant capacity in comparison with other drying conditions, revealing that these drying conditions are more suitable for drying VitexAC leaves. However, freeze drying is costly and time-consuming; thus, vacuum drying at 65C is suggested for drying the VitexAC leaves as the starting materials for further processing steps. Practical Applications: As drying is an important process to prepare starting materials for further processing steps, it is important to compare different drying methods to identify the most suitable method with low cost and less effect on material quality. The results showed that inappropriate drying conditions resulted in big loss of bioactive compounds and antioxidant capacity. Vacuum drying at 65C was found to be the most suitable method, which can be easily applied for drying Vitex agnus-castus leaves in the industrial scale.

DOI 10.1111/jfpp.12506
Citations Scopus - 1
Co-authors C Scarlett, Vanquan Vuong
2015 Nguyen VT, Vuong QV, Bowyer MC, Altena IAV, Scarlett CJ, 'Effects of Different Drying Methods on Bioactive Compound Yield and Antioxidant Capacity of Phyllanthus amarus', Drying Technology, 33 1006-1017 (2015) [C1]
DOI 10.1080/07373937.2015.1013197
Citations Scopus - 5Web of Science - 4
Co-authors C Scarlett, Vanquan Vuong
2015 Thuy Pham HN, Nguyen VT, Vuong QV, Bowyer MC, Scarlett CJ, 'Effect of Extraction Solvents and Drying Methods on the Physicochemical and Antioxidant Properties of Helicteres hirsuta Lour. Leaves', Technologies, 3 285-301 (2015) [C1]
DOI 10.3390/technologies3040285
Co-authors C Scarlett, Vanquan Vuong
2015 Vuong QV, Chalmers AC, Jyoti Bhuyan D, Bowyer MC, Scarlett CJ, 'Botanical, phytochemical, and anticancer properties of the eucalyptus species', Chemistry and Biodiversity, 12 907-924 (2015) [C1]

Copyright © 2015 Verlag Helvetica Chimica Acta AG, Zürich.The genus Eucalyptus (Myrtaceae) is mainly native to Australia; however, some species are now distributed globally. Euc... [more]

Copyright © 2015 Verlag Helvetica Chimica Acta AG, Zürich.The genus Eucalyptus (Myrtaceae) is mainly native to Australia; however, some species are now distributed globally. Eucalyptus has been used in indigenous Australian medicines for the treatment of a range of aliments including colds, flu, fever, muscular aches, sores, internal pains, and inflammation. Eucalyptus oils containing volatile compounds have been widely used in the pharmaceutical and cosmetics industries for a multitude of purposes. In addition, Eucalyptus extracts containing nonvolatile compounds are also an important source of key bioactive compounds, and several studies have linked Eucalyptus extracts with anticancer properties. With the increasing research interest in Eucalyptus and its health properties, this review briefly outlines the botanical features of Eucalyptus, discusses its traditional use as medicine, and comprehensively reviews its phytochemical and anticancer properties and, finally, proposes trends for future studies.

DOI 10.1002/cbdv.201400327
Citations Scopus - 2Web of Science - 2
Co-authors Anita Chalmers, C Scarlett, Vanquan Vuong
2014 Vuong QV, Hirun S, Phillips PA, Chuen TLK, Bowyer MC, Goldsmith CD, Scarlett CJ, 'Fruit-derived phenolic compounds and pancreatic cancer: Perspectives from Australian native fruits', JOURNAL OF ETHNOPHARMACOLOGY, 152 227-242 (2014) [C1]
DOI 10.1016/j.jep.2013.12.023
Citations Scopus - 13Web of Science - 7
Co-authors C Scarlett, Vanquan Vuong
2014 Zayas H, Holdsworth CI, Bowyer MC, McCluskey A, 'Evaluation of 4-substituted styrenes as functional monomers for the synthesis of theophylline-specific molecularly imprinted polymers.', Org Biomol Chem, 12 6994-7003 (2014) [C1]
DOI 10.1039/c4ob00517a
Citations Scopus - 5Web of Science - 4
Co-authors Clovia Holdsworth, Adam Mccluskey
2014 Vuong QV, Sadeqzadeh E, Hirun S, Goldsmith CD, Zammitt N, Bowyer MB, et al., 'Phenolic Compounds, Antioxidant and Anti-Cancer Properties of the Australian Maroon Bush Scaevola spinescens (Goodeniaceae)', Journal of Bioanalysis & Biomedicine, S12 (2014) [C1]
DOI 10.4172/1948-593X.S12-002
Co-authors Jennette Sakoff, C Scarlett, Judith Weidenhofer, Vanquan Vuong, Rick Thorne
2014 Vuong QV, Hirun S, Chuen TLK, Goldsmith CD, Bowyer MC, Chalmers AC, et al., 'Physicochemical composition, antioxidant and anti-proliferative capacity of a lilly pilly (Syzygium paniculatum) extract', JOURNAL OF HERBAL MEDICINE, 4 134-140 (2014)
DOI 10.1016/j.hermed.2014.04.003
Citations Web of Science - 3
Co-authors C Scarlett, Vanquan Vuong, Anita Chalmers
2014 Vuong Q, Goldsmith C, Dang T, Nguyen V, Bhuyan D, Sadeqzadeh E, et al., 'Optimisation of Ultrasound-Assisted Extraction Conditions for Phenolic Content and Antioxidant Capacity from Euphorbia tirucalli Using Response Surface Methodology', Antioxidants, 3 604-617 (2014) [C1]
DOI 10.3390/antiox3030604
Co-authors C Scarlett, Vanquan Vuong
2013 Brisbane C, McCluskey A, Bowyer M, Holdsworth CI, 'Molecularly imprinted films of acrylonitrile/methyl methacrylate/acrylic acid terpolymers: influence of methyl methacrylate in the binding performance of L-ephedrine imprinted films', Organic & Biomolecular Chemistry, 11 2872-2884 (2013) [C1]
DOI 10.1039/c3ob40332g
Citations Scopus - 2Web of Science - 2
Co-authors Clovia Holdsworth, Adam Mccluskey
2013 Vuong QV, Hirun S, Roach PD, Bowyer MC, Phillips PA, Scarlett CJ, 'Effect of extraction conditions on total phenolic compounds and antioxidant activities of Carica papaya leaf aqueous extracts', JOURNAL OF HERBAL MEDICINE, 3 104-111 (2013) [C1]
DOI 10.1016/j.hermed.2013.04.004
Citations Scopus - 22Web of Science - 19
Co-authors Vanquan Vuong, C Scarlett, Paul Roach
2012 Turner NW, Holdsworth CI, McCluskey A, Bowyer MC, 'N-2-propenyl-(5-dimethylamino)-1-naphthalene sulfonamide, a novel fluorescent monomer for the molecularly imprinted polymer-based detection of 2,4-dinitrotoluene in the gas phase', Australian Journal of Chemistry, 65 1405-1412 (2012) [C1]
Citations Scopus - 5Web of Science - 5
Co-authors Clovia Holdsworth, Adam Mccluskey
2011 Vuong QV, Bowyer MC, Roach PD, 'L-Theanine: Properties, synthesis and isolation from tea', Journal of the Science of Food and Agriculture, 91 1931-1939 (2011) [C1]
DOI 10.1002/jsfa.4373
Citations Scopus - 38Web of Science - 28
Co-authors Paul Roach, Vanquan Vuong
2010 Turner NW, Holdsworth CI, Donne SW, McCluskey A, Bowyer MC, 'Microwave induced MIP synthesis: comparative analysis of thermal and microwave induced polymerisation of caffeine imprinted polymers', New Journal of Chemistry, 34 686-692 (2010) [C1]
DOI 10.1039/b9nj00538b
Citations Scopus - 25Web of Science - 21
Co-authors Scott Donne, Adam Mccluskey, Clovia Holdsworth
2009 Turner NW, Holmes NP, Brisbane CE, McGeachie AB, Bowyer MC, McCluskey A, Holdsworth CI, 'Effect of template on the formation of phase-inversed molecularly imprinted polymer thin films: An assessment', Soft Matter, 5 3663-3671 (2009) [C1]
DOI 10.1039/b902468a
Citations Scopus - 9Web of Science - 8
Co-authors Clovia Holdsworth, Adam Mccluskey
2009 Zayas HA, Bowyer MC, Gordon CP, Holdsworth CI, McCluskey A, 'Synthesis of biaryl-styrene monomers by microwave-assisted Suzuki coupling', Tetrahedron Letters, 50 5894-5895 (2009) [C1]
DOI 10.1016/j.tetlet.2009.07.117
Citations Scopus - 10Web of Science - 9
Co-authors Clovia Holdsworth, Adam Mccluskey
2007 McCluskey A, Holdsworth CI, Bowyer MC, 'Molecularly imprinted polymers (MIPs): sensing, an explosive new opportunity?', Organic & Biomolecular Chemistry, 5 3233-3244 (2007) [C1]
DOI 10.1039/b708660a
Citations Scopus - 58Web of Science - 55
Co-authors Clovia Holdsworth, Adam Mccluskey
2007 Wills RB, Soegiarto L, Bowyer MC, 'Use of a solid mixture containing diethylenetriamine/nitric oxide (DETANO) to liberate nitric oxide gas in the presence of horticultural produce to extend postharvest life', Nitric Oxide - Biology and Chemistry, 17 44-49 (2007) [C1]
DOI 10.1016/j.niox.2007.05.003
Citations Scopus - 20Web of Science - 19
Co-authors Ron Wills
2007 Booker KM, Bowyer MC, Lennard CJ, Holdsworth CI, McCluskey A, 'Molecularly imprinted polymers and room temperature ionic liquids: Impact of template on polymer morphology', Australian Journal of Chemistry, 60 51-56 (2007) [C1]
DOI 10.1071/ch06284
Citations Scopus - 17Web of Science - 16
Co-authors Clovia Holdsworth, Adam Mccluskey
2006 Booker KM, Bowyer MC, Holdsworth CI, McCluskey A, 'Efficient preparation and improved sensitivity of molecularly imprinted polymers using room temperature ionic liquids', Chemical Communications, 1730-1732 (2006) [C1]
DOI 10.1039/b517886j
Citations Scopus - 36Web of Science - 38
Co-authors Clovia Holdsworth, Adam Mccluskey
2006 Snowdon EM, Bowyer MC, Grbin PR, Bowyer PK, 'Mousy off-flavor: A review', Journal of Agricultural and Food Chemistry, 54 6465-6474 (2006) [C1]
DOI 10.1021/jf0528613
Citations Scopus - 51Web of Science - 43
2006 Schwarz LJ, Bowyer MC, Holdsworth CI, McCluskey A, 'Synthesis and evaluation of a molecularly imprinted polymer selective to 2,4,6-trichloroanisole', Australian Journal of Chemistry, 59 129-134 (2006) [C1]
DOI 10.1071/CH05318
Citations Scopus - 19Web of Science - 18
Co-authors Adam Mccluskey, Clovia Holdsworth
2005 Holdsworth CI, Bowyer MC, Lennard C, McCluskey A, 'Formulation of cocaine-imprinted polymers utilizing molecular modelling and NMR analysis', Australian Journal of Chemistry, 58 315-320 (2005) [C1]
DOI 10.1071/CH04138
Citations Scopus - 28Web of Science - 28
Co-authors Clovia Holdsworth, Adam Mccluskey
2004 Schwarz LJ, Holdsworth CI, McCluskey A, Bowyer MC, 'Synthesis and Evaluation of a Molecularly Imprinted Polymer Selective to 2,4,6-Trichlorophenol', Australian Journal of Chemistry, 57 759-764 (2004) [C1]
DOI 10.1071/CH04004
Citations Scopus - 34Web of Science - 35
Co-authors Adam Mccluskey, Clovia Holdsworth
2004 Bowyer MC, Gordon CM, Leitch SK, McCluskey A, Ritchie C, 'Indium-Mediated Addition of 4-Bromocrotonic Acid to Aldehydes and Ketones - A Simple, High Yielding Route to Alpha-Allyl-Beta-Hydroxy Carboxylic Acids', Australian Journal of Chemistry: an international journal for chemical science, 57 135-137 (2004) [C1]
DOI 10.1071/CH03212
Citations Scopus - 6Web of Science - 5
Co-authors Adam Mccluskey
2004 Badiyan D, Wills RB, Bowyer MC, 'Use of a nitric oxide donor compound to extend the vase life of cut flowers', Hortscience, 39 1371-1372 (2004) [C1]
Citations Scopus - 12Web of Science - 10
Co-authors Ron Wills
2004 McCluskey A, Bowyer MC, 'Synthetic antibodies and the Australian wine industry: A Hunter Valley solution to cork taint?', Australian & New Zealand Grapegrower & Winemaker, 2004 111-115 (2004) [C3]
Co-authors Adam Mccluskey
2003 Ackland S, Bowyer MC, Baldwin ML, Garner JA, Walkom CC, Sakoff JA, McCluskey A, 'Cantharidin analogues: synthesis and evaluation of growth inhibition in a panel of selected tumour cell lines', Bioorganic Chemistry, 31 68-79 (2003) [C1]
DOI 10.1016/S0045-2068(02)00524-2
Citations Scopus - 79Web of Science - 66
Co-authors Adam Mccluskey, Stephen Ackland, Jennette Sakoff
2003 Bowyer MC, Wills RB, Badiyan D, Ku VV-V, 'Extending the postharvest life of carnations with nitric oxide - comparison of fumigation and in vivo delivery', Postharvest Biology and Technology, 30 281-286 (2003) [C1]
DOI 10.1016/S0925-5214(03)00114-5
Citations Scopus - 37Web of Science - 33
Co-authors Ron Wills
2002 McCluskey A, Atherton MA, Walkom CC, Bowyer M, Sim A, Young D, Sakoff J, 'The first two cantharidin analogues displaying PP1 selectivity', Bioorganic & Medicinal Chemistry Letters, 12 391-393 (2002) [C1]
Citations Scopus - 41Web of Science - 39
Co-authors Alistair Sim, Jennette Sakoff, Mirella Atherton, Adam Mccluskey
2001 McCluskey A, Walkom CC, Bowyer MC, Ackland SP, Gardiner E, Sakoff JA, 'Cantharimides: A new class of modified cantharidin analogues inhibiting protein phosphatases 1 and 2A', Bioorganic & Medicinal Chemistry Letters, 11 2941-2946 (2001) [C1]
Citations Scopus - 62Web of Science - 58
Co-authors Adam Mccluskey, Stephen Ackland, Jennette Sakoff
2000 Keane MA, Bowyer MC, Biggs SR, Galvin KP, Hosken RW, 'Particle size analysis of microfluidised dairy emulsions', AUSTRALIAN JOURNAL OF DAIRY TECHNOLOGY, 55 94-94 (2000)
Co-authors Kevin Galvin
2000 Bowyer MC, 'Anhydride Modified Cantharidin Analogues: Synthesis, Inhibition of Protein Phosphatases 1 and 2A and Anticancer Activity', Bioorganic & Medicinal Chemistry Letters, 10 1687-1690 (2000) [C1]
Citations Scopus - 73Web of Science - 71
Co-authors Adam Mccluskey, Alistair Sim, Jennette Sakoff
Show 47 more journal articles

Conference (15 outputs)

Year Citation Altmetrics Link
2016 Pristijono P, Bowyer M, Scarlett C, Vuong Q, Stathopoulos C, Golding J, 'Effect of UV-C irradiation on sprouting of potatoes in storage' (2016)
Co-authors Vanquan Vuong, C Scarlett
2015 Pristijono P, Golding J, Bowyer M, Scarlett C, Stathopoulos, 'Postharvest UV-C irradiation improves the quality of tomatoes and limes' (2015)
Co-authors C Scarlett
2015 Bond D, Turner A, Richmond R, Sadeqzadeh E, Vuong Q, Bhuyan D, et al., 'THE SEARCH FOR NOVEL TREATMENT AGENTS FOR PANCREATIC CANCER: TALES FROM THE LAND AND SEA', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY (2015) [E3]
Co-authors Vanquan Vuong, Jennette Sakoff, Anita Chalmers, Troy Gaston, Judith Weidenhofer, C Scarlett
2015 Predebon M, Bond D, Brzozowski J, Jankowski H, Deane F, Tarleton M, et al., 'A BISPIDINONE ANALOGUE INDUCES AN APOPTOSIS-MEDIATED CYTOTOXIC EFFECT ON PANCREATIC CANCER CELLS IN VITRO', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY (2015) [E3]
Co-authors C Scarlett, Judith Weidenhofer, Adam Mccluskey
2014 Sadeqzadeh E, Vuong QV, Goldsmith CD, Nguyen VT, Bhuyan DJ, Trung TD, et al., 'A NATURAL PRODUCT DRUG DISCOVERY PIPELINE FOR NOVEL PANCREATIC CANCER THERAPIES: A NEW CANCER RESEARCH HUB FOR THE HUNTER REGION OF NSW', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY (2014) [E3]
Co-authors Judith Weidenhofer, Rick Thorne, Troy Gaston, Vanquan Vuong, C Scarlett, Natalie Moltschaniwskyj, Anita Chalmers
2013 Holdsworth CI, Diah A, Romano E, Mahinay D, Quirino J, Holdsworth J, Bowyer M, 'Characterisation of Functional Polymeric Materials by Capillary Electrophoresis', Abstracts, 2nd International Congress on Advanced Materials (AM2013) (2013) [E3]
Co-authors John Holdsworth, Clovia Holdsworth
2013 Holdsworth CI, Diah A, Romano E, Mahinay D, Quirino J, Holdsworth J, Bowyer M, 'Characterisation of Functional Polymeric Materials by Capillary Electrophoresis', Abstracts, 2nd International Congress on Advanced Materials (AM2013) (2013) [E3]
Co-authors John Holdsworth, Clovia Holdsworth
2003 Wills RB, Bowyer MC, Leshem Y, 'Use of Nitric Oxide to Extend the Postharvest Life of Horticultural Produce', Acta Horticulturae (2003) [E1]
Citations Scopus - 2Web of Science - 1
Co-authors Ron Wills
2002 Wills RB, Bowyer MC, 'Use of Nitric Oxide to Extend the Postharvest Life of Flowers', The Wildflower Business: Keys to Progress and Profit (2002) [E2]
Co-authors Ron Wills
2000 Keane MA, Bowyer MC, Hosken RW, 'Relationship Between Particle Size and Creaminess in Microfluidized Low Fat Dairy Emulsions', CHEMECA 2000 (2000) [E1]
1999 Keane MA, McMillan W, Bowyer MC, Galvin KP, Biggs S, Hosken RW, 'Microsctructure and sensory investigation of frozen deserts containing pectin', 10th World COngress of Food Science & Technology Abstracts (1999) [E3]
Co-authors Kevin Galvin
1999 Keane MA, McMillan W, Nada GGAS, Bowyer MC, Galvin K, Biggs S, Hosken RW, 'Relation of particle size and sensory characteristics of Microfluidized reduced fat ice cream', 10th World Congress of Food Science and Technology Abstracts (1999) [E3]
1999 Keane MA, McMillan W, Bowyer MC, Galvin K, Biggs S, Hosken RW, 'Laser Scanning Confocal Microscopy of a Dairy Based Emulsion', Chemeca 99 (1999) [E1]
1999 Keane MA, Heenan CN, Bowyer MC, Hosken RW, 'Application of Inulin as a Fat Replacer in Dairy Foods', Proceedings of the Nutrition Society of Australia (1999) [E3]
1998 Keane MA, Bowyer MC, Hosken RW, 'Acceptance of a low fat dairy desert by adolescents', Proceedings of the Nutrition Society (1998) [E1]
Show 12 more conferences
Edit

Grants and Funding

Summary

Number of grants 25
Total funding $4,098,290

Click on a grant title below to expand the full details for that specific grant.


20146 grants / $2,911,393

Food & Beverage Supply Chain Optimisation Industrial Transformation Training Centre$2,119,872

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team Professor Rick Middleton, Associate Professor Regina Berretta, Associate Professor Michael Bowyer, Doctor Ali Eshragh, Doctor Masoud Talebian, Associate Professor Behnam Fahimnia, Professor Mathieu Savelsbergh, Professor Natashia Boland, Dr Costas Stathopoulos, Professor John Bartholdi, Doctor Simon Dunstall, Mrs Carlee McGowan, Mr Robert McMahon, Mr Tim Norris, Mr Robert Scoines, Associate Professor Christopher Scarlett
Scheme Industrial Transformation Training Centres
Role Investigator
Funding Start 2014
Funding Finish 2016
GNo G1301004
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

ARC ITTC ELS subaccount$621,021

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team Associate Professor Michael Bowyer, Associate Professor Christopher Scarlett
Scheme Industrial Transformation Training Centres
Role Lead
Funding Start 2014
Funding Finish 2016
GNo GS150004
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Food & Beverage Supply Chain Optimisation Industrial Transformation Training Centre$90,000

Funding body: Coca Cola Amatil (Australia)

Funding body Coca Cola Amatil (Australia)
Project Team Professor Rick Middleton, Associate Professor Regina Berretta, Associate Professor Michael Bowyer, Doctor Ali Eshragh, Associate Professor Christopher Scarlett, Doctor Masoud Talebian, Associate Professor Behnam Fahimnia, Professor Mathieu Savelsbergh, Professor Natashia Boland, Dr Costas Stathopoulos, Professor John Bartholdi, Doctor Simon Dunstall, Mrs Carlee McGowan, Mr Robert McMahon, Mr Robert Scoines, Mr Tim Norris
Scheme Industrial Transformation Training Centres Partner Funding
Role Investigator
Funding Start 2014
Funding Finish 2016
GNo G1301129
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Food & Beverage Supply Chain Optimisation Industrial Transformation Training Centre$30,000

Funding body: Sanitarium Health and Wellbeing Company

Funding body Sanitarium Health and Wellbeing Company
Project Team Professor Rick Middleton, Associate Professor Regina Berretta, Associate Professor Michael Bowyer, Doctor Ali Eshragh, Associate Professor Christopher Scarlett, Doctor Masoud Talebian, Associate Professor Behnam Fahimnia, Professor Mathieu Savelsbergh, Professor Natashia Boland, Dr Costas Stathopoulos, Professor John Bartholdi, Doctor Simon Dunstall, Mrs Carlee McGowan, Mr Robert McMahon, Mr Robert Scoines, Mr Tim Norris
Scheme Industrial Transformation Training Centres Partner Funding
Role Investigator
Funding Start 2014
Funding Finish 2016
GNo G1301130
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Food & Beverage Supply Chain Optimisation Industrial Transformation Training Centre$30,000

Funding body: Sunrice

Funding body Sunrice
Project Team Professor Rick Middleton, Associate Professor Regina Berretta, Associate Professor Michael Bowyer, Doctor Ali Eshragh, Associate Professor Christopher Scarlett, Doctor Masoud Talebian, Associate Professor Behnam Fahimnia, Professor Mathieu Savelsbergh, Professor Natashia Boland, Dr Costas Stathopoulos, Professor John Bartholdi, Doctor Simon Dunstall, Mrs Carlee McGowan, Mr Robert McMahon, Mr Robert Scoines, Mr Tim Norris
Scheme Industrial Transformation Training Centres Partner Funding
Role Investigator
Funding Start 2014
Funding Finish 2016
GNo G1301131
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Identification and evaluation of anti-pancreatic cancer activity of cytotoxic compounds extracted from Australian sea sponges: a pilot study$20,500

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Associate Professor Christopher Scarlett, Doctor Quan Vuong, Doctor Jude Weidenhofer, Doctor Rick Thorne, Associate Professor Michael Bowyer, Doctor Troy Gaston
Scheme Project Grant
Role Investigator
Funding Start 2014
Funding Finish 2015
GNo G1401452
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

20121 grants / $15,000

2011 Emerging Research Leaders Program$15,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Associate Professor Michael Bowyer
Scheme Emerging Research Leaders Program
Role Lead
Funding Start 2012
Funding Finish 2012
GNo G1200620
Type Of Funding Internal
Category INTE
UON Y

20081 grants / $1,740

The Fifth International Workship on Molecular Imprinting (MIP 2008), Kobe, Japan, 7/9/2008 - 11/9/2008$1,740

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Associate Professor Michael Bowyer
Scheme Travel Grant
Role Lead
Funding Start 2008
Funding Finish 2008
GNo G0189036
Type Of Funding Internal
Category INTE
UON Y

20073 grants / $588,942

Chemical listening devices: Novel sensors targeting the clandestine manufacture and transport of illicit drugs and explosives$378,942

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team Professor Adam McCluskey, Associate Professor Michael Bowyer, Doctor Clovia Holdsworth, Professor Christopher Lennard
Scheme Linkage Projects
Role Investigator
Funding Start 2007
Funding Finish 2009
GNo G0186611
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Chemical listening devices: Novel sensors targeting the clandestine manufacture and transport of illicit drugs and explosives$105,000

Funding body: Australian Federal Police

Funding body Australian Federal Police
Project Team Professor Adam McCluskey, Associate Professor Michael Bowyer, Doctor Clovia Holdsworth, Professor Christopher Lennard
Scheme Linkage Projects Partner Funding
Role Investigator
Funding Start 2007
Funding Finish 2009
GNo G0187330
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

Selective Detection and Removal of Organochlorine Residues via MIPs$105,000

Funding body: Entech Industries Pty Ltd

Funding body Entech Industries Pty Ltd
Project Team Professor Adam McCluskey, Doctor Clovia Holdsworth, Associate Professor Michael Bowyer
Scheme Postgraduate Research Scholarship
Role Investigator
Funding Start 2007
Funding Finish 2010
GNo G0187721
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

20061 grants / $1,500

MIP 2006 - 4th International Workshop on Molecularly Imprinted Polymers, Cardiff Wales, 10-14 September 2006$1,500

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Associate Professor Michael Bowyer
Scheme Travel Grant
Role Lead
Funding Start 2006
Funding Finish 2006
GNo G0186777
Type Of Funding Internal
Category INTE
UON Y

20044 grants / $457,336

Selective detection and removal of contaminants that have an adverse impact on Australian raw sugar quality$190,000

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team Professor Adam McCluskey, Associate Professor Michael Bowyer, Dr M O'Shea
Scheme Linkage Projects
Role Investigator
Funding Start 2004
Funding Finish 2006
GNo G0183626
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

In-field sensors for the detection of illicit drugs$171,336

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team Professor Adam McCluskey, Associate Professor Michael Bowyer
Scheme Linkage Projects
Role Investigator
Funding Start 2004
Funding Finish 2006
GNo G0184254
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Selective detection and removal of contaminants that have adverse impact on Australian raw sugar quality$51,000

Funding body: Bureau of Sugar Experiment Stations

Funding body Bureau of Sugar Experiment Stations
Project Team Professor Adam McCluskey, Associate Professor Michael Bowyer
Scheme Linkage Projects Partner Funding
Role Investigator
Funding Start 2004
Funding Finish 2006
GNo G0184030
Type Of Funding Not Known
Category UNKN
UON Y

In-field sensors for the detection of illicit drugs$45,000

Funding body: Australian Federal Police

Funding body Australian Federal Police
Project Team Professor Adam McCluskey, Associate Professor Michael Bowyer
Scheme Linkage Projects Partner Funding
Role Investigator
Funding Start 2004
Funding Finish 2006
GNo G0185067
Type Of Funding Not Known
Category UNKN
UON Y

20031 grants / $750

Synthetic Receptors - 2003, The first World Congress on Synthetic Receptors Lisbon, Portugal 15-17 October 2003$750

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Associate Professor Michael Bowyer
Scheme Travel Grant
Role Lead
Funding Start 2003
Funding Finish 2003
GNo G0183233
Type Of Funding Internal
Category INTE
UON Y

20022 grants / $58,000

Delaying postharvest senescence of cut flowers using nitric oxide.$50,000

Funding body: Rural Industries Research & Development Corporation

Funding body Rural Industries Research & Development Corporation
Project Team Emeritus Professor Ronald Wills, Associate Professor Michael Bowyer
Scheme Research and Development Project
Role Investigator
Funding Start 2002
Funding Finish 2003
GNo G0182218
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Endogenous Application of Nitric Oxide to Postharvest Horticultural Produce to Delay Senescence$8,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Associate Professor Michael Bowyer
Scheme Project Grant
Role Lead
Funding Start 2002
Funding Finish 2002
GNo G0181387
Type Of Funding Internal
Category INTE
UON Y

20002 grants / $28,708

Selective detection of Trichloroanisole and other flavour contaminants in wines using molecularly imprinted polymer technology.$26,950

Funding body: Grape & Wine Research and Development Corporation

Funding body Grape & Wine Research and Development Corporation
Project Team Professor Adam McCluskey, Associate Professor Michael Bowyer
Scheme Project Grant
Role Investigator
Funding Start 2000
Funding Finish 2000
GNo G0180158
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

MIP 2000, 3 - 5 July 2000.$1,758

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Associate Professor Michael Bowyer
Scheme Travel Grant
Role Lead
Funding Start 2000
Funding Finish 2000
GNo G0179775
Type Of Funding Internal
Category INTE
UON Y

19992 grants / $20,421

Selective detection of Trichloroanisole and other flavour contaminants in wines using molecularly imprinted polymer technology$20,000

Funding body: Grape & Wine Research and Development Corporation

Funding body Grape & Wine Research and Development Corporation
Project Team Professor Adam McCluskey, Associate Professor Michael Bowyer
Scheme Project Grant
Role Investigator
Funding Start 1999
Funding Finish 1999
GNo G0178612
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Inorganic Chemistry '99. Wellington, New Zealand. 31 January - 4 February, 1999$421

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Associate Professor Michael Bowyer
Scheme Travel Grant
Role Lead
Funding Start 1999
Funding Finish 1999
GNo G0179106
Type Of Funding Internal
Category INTE
UON Y

19971 grants / $4,500

Stereoselective synthesis of alkanamides from echinacea$4,500

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Associate Professor Michael Bowyer
Scheme Project Grant
Role Lead
Funding Start 1997
Funding Finish 1997
GNo G0176749
Type Of Funding Internal
Category INTE
UON Y

19951 grants / $10,000

Synthesis of Indole Analogues of ISoflavonoid Phytoestrogens.$10,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Associate Professor Michael Bowyer
Scheme New Staff Grant
Role Lead
Funding Start 1995
Funding Finish 1995
GNo G0176053
Type Of Funding Internal
Category INTE
UON Y
Edit

Research Supervision

Number of supervisions

Completed12
Current11

Total current UON EFTSL

PhD2.15

Current Supervision

Commenced Level of Study Research Title / Program / Supervisor Type
2015 PhD Waste Utilisation
PhD (Food Science), Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2015 PhD Identification and Isolation of Bioactive Compounds from Selected Australian and Vietnamese Flora as Novel Agents for Prevention and Treatment of Pancreatic Cancer
PhD (Food Science), Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2015 PhD Phytochemicals from Vietnamese and Australian Native Plants as Novel Anti-Cancer Agents for Gastro-Pancreatic Malignancies
PhD (Food Science), Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2015 PhD Anticancer Compounds from Plants Against Pancreatic Cancer Cells: Extraction, Purification and Characterization
PhD (Food Science), Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2015 PhD Edible Films for Improving Postharvest Life of Fresh Horticultural Produce.
PhD (Food Science), Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2014 PhD Interaction of gaseous signalling molecules ethylene, nitric oxide and hydrogen sulphide, on postharvest metabolism of banana fruit and the leafy vegetable, pak choy.
PhD (Food Science), Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2014 PhD Brown Algae as a Source of Bioactive Compounds for Pancreatic Cancer Treatment
PhD (Food Science), Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2014 PhD Bioactive Compounds, Antioxidant and Anti-Pancreatic Cancer Capacity of Two Vietnamese Medicinal Plants: Phyllanthus Amarus and Paramignya Trimera
PhD (Food Science), Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2014 PhD Phytochemicals Derived From Australian Eucalypts as Anticancer Agents for Pancreatic Malignancies
PhD (Food Science), Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2013 PhD Mechanistic Aspects of Molecular Imprinting: Effects on Binding Performance
PhD (Chemistry), Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2005 PhD Use of nitric oxide in extending the postharvest life of flowers & green vegetables
Food Science & Biotechnology, University of Newcastle
Principal Supervisor

Past Supervision

Year Level of Study Research Title / Program / Supervisor Type
2015 PhD Factors Influencing the Physiological and Perceptual Decision-Making Demands of Australian Football Field Umpires
PhD (Exercise & Sport Science), Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2014 PhD Exploring Signal Transduction Mechanisms in Molecularly Imprinted Polymers for Forensic Applications
PhD (Chemistry), Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2014 PhD The Use of Game-Based Training to Provide a Match-Specific Environment for Cricket Players
PhD (Exercise & Sport Science), Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2012 PhD Development of Molecularly Imprinted Polymers for Amphetamine Type Substance Recognition in Aqueous Environments
PhD (Chemistry), Faculty of Science and Information Technology, The University of Newcastle
Sole Supervisor
2012 PhD Synthesis, Characterisation and Evaluation of Biphenyl Monomers for Molecular Imprinting Applications
PhD (Chemistry), Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2010 PhD Towards the Development of a Benzylpiperazine Specific Molecular Imprinted Polymer
PhD (Chemistry), Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2010 PhD Optimisation of Molecularly Imprinted Polymeric Films for the Detection of L-Ephedrine
PhD (Chemistry), Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2010 PhD Characterisation and Improved Performance of Molecularly Imprinted Polymers Prepared Using Room Temperature Ionic Liquids
PhD (Chemistry), Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2009 PhD Comparative Effects of Nitric Oxide Gas and Nitric Oxide Donors on the Postharvest Life of Cut Flowers and Brassica Vegetables
PhD (Food Science), Faculty of Science and Information Technology, The University of Newcastle
Principal Supervisor
2009 PhD Synthesis of 3,7-Diazabicyclo[3.3.1]nonan-9-ones as Potential Enantioselective Group Transfer Catalysts
PhD (Chemistry), Faculty of Science and Information Technology, The University of Newcastle
Principal Supervisor
2008 PhD Design and Synthesis of Molecularly Imprinted Polymers for the Selective Recognition of Small Chloro-Arene Contaminants
PhD (Chemistry), Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2006 PhD Extending the postharvest life of ornamentals using the nitric oxide donor compound, 2, 2¿- (hydroxynitrosohydrazino)-bisethanamine
PhD (Food Science), Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
Edit

Associate Professor Michael Bowyer

Position

Associate Professor
Deputy Head - Faculty of Science & IT
School of Environmental and Life Sciences
Faculty of Science and Information Technology

Focus area

Chemistry

Contact Details

Email michael.bowyer@newcastle.edu.au
Phone (02) 4921 2005 (Callaghan) (02) 4348 4119 (Ourimbah)
Fax (02) 4921 7949 (02) 4348 4145

Office

Room V201b (Callaghan) SO1.48 (Ourimbah)
Building Science Offices
Location Ourimbah
10 Chittaway Road
Ourimbah, NSW 2258
Australia
Edit