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Career Summary

Biography

In Leeds, I established an international reputation in the field of nutritional genetics in relation to genes coding for proteins involved in folate and B-vitamin metabolism and function. I have authored a list of almost 100 publications including several reviews in high impact journals and books. In the years preceding my move to Australia in July 2003, I held around $500,000 AUD in funding including grants of $160,000 AUD from the British Heart Foundation, $145,000 AUD from Kelloggs and $85,000 AUD from the Association for Spina Bifida and Hydrocephalus. I am also an elected Fellow of the Society of Biology (London), and a Fellow of the Royal College of Pathologists (London). My research interests cover the chemistry, nutritional biochemistry, molecular biology and genetics of B-vitamins, especially folate, and their role in the metabolism of homocysteine, which is now an acknowledged risk factor for many degenerative diseases. In particular, my research efforts are focused on common allelic variants of genes (single nucleotide polymorphisms, SNPs) that code for folate dependent enzymes and carriers. My contribution in this area has led to improved understanding of how folate nutrition and genetics interact to modulate disease development. This work has shed light on how folate metabolism, status, nutrition and genetics impact on several disorders such as spina bifida, other serious conditions affecting pregnancy outcome, vascular disease, cancer, and neurological disorder. Two such papers for example look at the effect of folate SNPs and status on the efficacy of antifolate cancer chemotherapy in colon cancer cells. My publications span this area of interest and range from nutrient analysis and nutrient-gene interactions to the role of B-vitamins in human evolutionary processes. My publications show considerable collaboration with British and International colleagues. Since arriving to teach in the Bachelor of Food Science & Human Nutrition program in the School of Environmental & Life Sciences (SELS) on the Ourimbah Campus of the University of Newcastle in July 2003, I have set up a well-equipped PC2 laboratory directed to molecular nutrition which includes real-time PCR equipment, LC-MS, an imaging platform and other key technologies. I have re-established my research and am now co-supervising several PhD/Honours students working in collaboration with Dr Martin Veysey (Gosford Hospital), Dr Paul Roach (SELS) and Dr Zoe Yates. Most of these students are working in the area of B-vitamin nutrient-gene interactions and adenoma. I am the Chief facilitator for the Nutrition, Food & Health Research Group at Ourimbah. Through the School, the University and my collaborations, I have been able to access over $450,000 in set up and research funds, and am a CI on a large ARC grant with Drs Veysey and Roach. I also have an active interest in the issues associated with mandatory fortification of grain at source with synthetic folic acid. This is an area on which I have published extensively, including a recent Nature-Reviews Genetics article looking at the genetic and health implications of fortification. I am a member of the Folate Scientific Advisory Group of FSANZ looking at the implementation of mandatory folate fortification in Australia. Additionally, I have written an academic text book (July 2007) titled; Molecular Nutrition and Genomics: Nutrition & the Ascent of Humankind. This is a single author book, designed for students and researchers.

Qualifications

  • PhD, University of Leeds - UK, 18/11/1991
  • Bachelor of Science (Honours), University of Bradford, UK, 01/07/1983

Research

Research keywords

  • B-Vitamins
  • Birth defects
  • Cancer
  • Folic acid
  • Molecular Nutrition
  • Nutrient bioavailability
  • Nutrition and Human Evolution
  • Nutritional Biochemistry
  • Nutritional Genetics
  • Vascular disease
  • Vitamin B12

Research expertise

Expert in the analysis, biochemistry and genetics of B-vitamins and their related proteins. Major areas of interest are the nutritional genetics of folate and how this modifies disease risk, particularly chronic degenerative diseases like CVD and bowel cancer, and developmental disorders like NTD and autism. Other major interest is the role of human nutritional genetics in human evolution.

Fields of Research

CodeDescriptionPercentage
110300Clinical Sciences40
060499Genetics Not Elsewhere Classified30
111100Nutrition And Dietetics30

Memberships

Learned Academy.

  • Member - Royal College of Pathologists (London)
  • Editor - Society of Biology (London)
  • Editor - Society of Biology (London)

Appointments

Scientific advisor on mandatory fortification of the Australian diet with folic acid
FSANZ (Food standards Australia & New Zealand) (Australia)
01/01/2006

Awards

Distinction.

2006Vice-Chancellor's Citations for Outstanding Contributions to Student Learning
University of Newcastle (Australia)
Development of curricula and resources which reflect a command of the field

Recognition.

2005Faculty of Science & IT Teaching & Learning Award
University of Newcastle (Australia)

Invitations

All invitations relate to folate
Several both national and international, Australia (Numerous invitations to give presentations at academic fora nationally and internationally)
2007

Collaboration

Folic acid chemistry, metabolism and genetics in health and disease.

Administrative

Administrative expertise

Deputy Head of School; Complaints Officer: Served on various committees, perhaps most relevant is the Faculty Research, and Research & Traing Committee (Science & IT)

Teaching

Teaching keywords

  • Functional foods and health claims
  • Micronutrients
  • Nutrition through the lifecycle

Teaching expertise

Course co-ordinator for three courses: Micronutrients, Nutrition through the lifecycle, and Functional foods and health claims. Deliver all material (lectures and tutorials) on all three courses

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Highlighted Publications

For publications that are currently unpublished or in-press, details are shown in italics.

YearCitationAltmetricsLink
2005Lucock MD, Yates Z, 'Folic acid - vitamin and panacea or genetic time bomb?', Nature Reviews Genetics, 6 235-240 (2005) [C1]

DOI: 10.1038/nrg1558

Co-authors: Zoe Yates

2004Sohn K-J, Croxford R, Yates ZR, Lucock MD, Kim Y-I, 'Effect of the methylenetetrahydrofolate reductase C677T polymorphism on chemosensitivity of colon and breast cancer cells to 5-fluorouracil and methotrexate', Journal of the National Cancer Institute, 96 134-144 (2004) [C1]

DOI: 10.1093/jnci/djh

Co-authors: Zoe Yates

2004Sohn K-J, Smirnakis F, Moskovitz DN, Novakovic P, Yates ZR, Lucock MD, et al., 'Effects of folylpolyglutamate synthetase modulation on chemosensitivity of colon cancer cells to 5-fluorouracil and methotrexate', GUT, 53 1825-1831 (2004) [C1]
2004Lucock MD, 'Is folic acid the ultimate functional food component for disease prevention?', British Medical Journal, 328 211-214 (2004) [C1]

Publications

For publications that are currently unpublished or in-press, details are shown in italics.

Click on a category title below to expand the list of citations for that specific category.

Book (1 outputs)

YearCitationAltmetricsLink
2007Lucock MD, Molecular Nutrition and Genomics: Nutrition and the Ascent of Mankind, John Wiley & Sons, Hoboken, 140 (2007) [A1]

Chapter (1 outputs)

YearCitationAltmetricsLink
2002Lucock M, 'A differential role for folate in developmental disorders, vascular disease and other clinical conditions: the importance of folate status and genotype', , Humana Press, Totowa NJ, 263-298 (2002) [B1]

Journal article (83 outputs)

YearCitationAltmetricsLink
2014Lucock MD, Martin CE, Yates ZR, Veysey M, 'Diet and Our Genetic Legacy in the Recent Anthropocene: A Darwinian Perspective to Nutritional Health', Journal of Evidence-Based Complementary and Alternative Medicine, 19 68-83 (2014)
2014Lucock M, Yates Z, Martin C, Choi JH, Boyd L, Tang S, et al., 'Vitamin D, folate, and potential early lifecycle environmental origin of significant adult phenotypes.', Evol Med Public Health, 2014 69-91 (2014)
2014Beckett EL, Yates Z, Veysey M, Duesing K, Lucock M, 'The role of vitamins and minerals in modulating the expression of microRNA.', Nutr Res Rev, 27 94-106 (2014)
2013Lucock M, Leeming R, 'Autism, seasonality and the environmental perturbation of epigenome related vitamin levels', Medical Hypotheses, 80 750-755 (2013) [C1]
2013Lucock M, Yates Z, Boyd L, Naylor C, Choi J, Ng X, et al., 'Vitamin C-related nutrient-nutrient and nutrient-gene interactions that modify folate status', European Journal of Nutrition, 52 569-582 (2013) [C1]
2013Lucock M, Yates Z, Martin C, Choi J, Boyd L, Tang S, et al., 'Hydrogen sulphide-related thiol metabolism and nutrigenetics in relation to hypertension in an elderly population', Genes & Nutrition, 8 221-229 (2013) [C1]
2013Lucock MD, Martin C, Boyd L, Naumovski N, Roach P, Yates Z, Veysey M, 'Response to 'calcium, phosphate and the risk of cardiovascular events and all-cause mortality in a population with stable coronary heart disease'', HEART, 99 349-350 (2013) [C3]
2012Lucock MD, Glanville T, Yates ZR, Walker J, Furst JE, Simpson N, 'Solar cycle predicts folate-sensitive neonatal genotypes at discrete phases of the first trimester of pregnancy: A novel folate-related human embryo loss hypothesis', Medical Hypotheses, 79 210-215 (2012) [C1]

Co-authors: John Furst, Zoe Yates

2012Lucock MD, 'Dietary supplements and altered mortality: A conflict of evolutionary medicine', Archives of Internal Medicine, 172 448-449 (2012) [C3]
2011Lucock MD, 'Folic acid: Beyond metabolism', Journal of Evidence-Based Complementary and Alternative Medicine, 16 102-113 (2011) [C1]
2011Lucock MD, Ng X, Boyd L, Skinner VM, Wai R, Tang S, et al., 'TAS2R38 bitter taste genetics, dietary vitamin C, and both natural and synthetic dietary folic acid predict folate status, a key micronutrient in the pathoaetiology of adenomatous polyps', Food & Function, 2 457-465 (2011) [C1]
2011Lucock M, 'Folic acid: Beyond metabolism', Journal of Evidence-Based Complementary and Alternative Medicine, 16 102-113 (2011) [C3]
2010Lucock MD, Glanville T, Ovadia L, Yates ZR, Walker J, Simpson N, 'Photoperiod at conception predicts C677T-MTHFR genotype: A novel gene-environment interaction', American Journal of Human Biology, 22 484-489 (2010) [C1]
2010Naumovski N, Veysey M, Ng X, Boyd L, Dufficy L, Blades BL, et al., 'The folic acid endophenotype and depression in an elderly population', Journal of Nutrition, Health and Aging, 14 829-833 (2010) [C1]
2009Ng X, Boyd L, Dufficy L, Naumovski N, Blades BL, Travers C, et al., 'Folate nutritional genetics and risk for hypertension in an elderly population sample', Journal of Nutrigenetics and Nutrigenomics, 2 1-8 (2009) [C1]
2009Lucock MD, Yates ZR, 'Folic acid fortification: A double-edged sword', Current Opinion in Clinical Nutrition & Metabolic Care, 12 555-564 (2009) [C1]
2009Sohn K-J, Jang H, Campan M, Weisenberger DJ, Dickhout J, Wang Y-C, et al., 'The methylenetetrahydrofolate reductase C677T mutation induces cell-specific changes in genomic DNA methylation and uracil misincorporation: A possible molecular basis for the site-specific cancer risk modification', International Journal of Cancer, 124 1999-2005 (2009) [C1]
2009Leeming RJ, Lucock MD, 'Autism: Is there a folate connection?', Journal of Inherited Metabolic Disease, 32 400-402 (2009) [C2]
2009Smith DR, Lucock MD, 'Should folate supplements be integrated with workplace nutrition programs?', Industrial Health, 47 449-451 (2009) [C3]
2008Ng X, Lucock MD, Veysey MJ, 'Physicochemical effect of pH and antioxidants on mono- and triglutamate forms of 5-methyltetrahydrofolate, and evaluation of vitamin stability in human gastric juice: Implications for folate bioavailability', Food Chemistry, 106 200-210 (2008) [C1]
2008Ng X, Lucock M, Veysey M, 'Physicochemical effect of pH and antioxidants on mono- and triglutamate forms of 5-methyltetrahydrofolate, and evaluation of vitamin stability in human gastric juice: Implications for folate bioavailability (vol 106, pg 200, 2008)', FOOD CHEMISTRY, 110 1000-1000 (2008) [C3]
2007Adams MC, Lucock MD, Stuart JE, Fardell S, Baker K, Ng X, 'Preliminary evidence for involvement of the folate gene polymorphism 19 bp deletion-DHFR in occurrence of autism', Neuroscience Letters, 422 24-29 (2007) [C1]
2007Lucock MD, Yates ZR, Ng X, Veysey MJ, Blades BL, Travers C, et al., 'Preliminary evidence for genetic selection of 677T-MTHFR by natural annual cycle of folate abundance', Journal of Nutrigenetics and Nutrigenomics, 1 24-29 (2007) [C1]
2006Dufficy L, Naumovski N, Ng X, Blades BL, Yates ZR, Travers C, et al., 'G80A reduced folate carrier SNP influences the absorption and cellular translocation of dietary folate and its association with blood pressure in an elderly population', Life Sciences, 79 957-966 (2006) [C1]
2006Lucock MD, 'Synergy of genes and nutrients: The case of homocysteine', Current Opinion in Clinical Nutrition and Metabolic Care, 9 748-756 (2006) [C1]
2006Lucock MD, Yates ZR, 'Synergy between 677 TT MTHFR genotype and related folate SNPs regulates homocysteine level', Nutrition Research, 26 180-185 (2006) [C1]
2006Glanville T, Yates ZR, Ovadia L, Walker JJ, Lucock MD, Simpson NAB, 'Fetal folate C677T methylenetetrahydrofolate reductase gene polymorphism and low birth weight', Journal of Obstetrics and Gynaecology, 26 11-14 (2006) [C1]
2005Lucock MD, Ng X, Veysey MJ, Yates ZR, 'Folic acid: An essential nutrient with added health benefits', Biologist, 52 21-27 (2005) [C1]
2005Yates ZR, Lucock MD, 'G80A reduced folate carrier SNP modulates cellular uptake of folate and affords protection against thrombosis via a non homocysteine related mechanism', Life Sciences, 77 2735-2742 (2005) [C1]
2005Lucock MD, Yates Z, 'Folic acid - vitamin and panacea or genetic time bomb?', Nature Reviews Genetics, 6 235-240 (2005) [C1]

DOI: 10.1038/nrg1558

Co-authors: Zoe Yates

2005Lucock MD, Yates ZR, 'Human genetic selection by folates', Nature Reviews Genetics, 6 online (2005) [C3]

Co-authors: Zoe Yates

2005Lucock MD, Roach PD, 'The antifolate activity of tea catechins (letter)', Cancer Research, 65 8573-8573 (2005) [C3]

Co-authors: Paul Roach

2004Sohn K-J, Smirnakis F, Moskovitz DN, Novakovic P, Yates ZR, Lucock MD, et al., 'Effects of folylpolyglutamate synthetase modulation on chemosensitivity of colon cancer cells to 5-fluorouracil and methotrexate', GUT, 53 1825-1831 (2004) [C1]
2004Sohn K-J, Croxford R, Yates ZR, Lucock MD, Kim Y-I, 'Effect of the methylenetetrahydrofolate reductase C677T polymorphism on chemosensitivity of colon and breast cancer cells to 5-fluorouracil and methotrexate', Journal of the National Cancer Institute, 96 134-144 (2004) [C1]

DOI: 10.1093/jnci/djh

Co-authors: Zoe Yates

2004Blackburn A, Bibby MC, Lucock MD, Nicolaou A, 'Temporal evaluation of methionine synthase and related metabolites in the MAC15A mouse adenocarcinoma animal model', International Journal of Cancer, 112 577-584 (2004) [C1]
2004Lucock MD, 'Is folic acid the ultimate functional food component for disease prevention?', BMJ USA, 4 127-130 (2004) [C1]
2004Lucock MD, 'Is folic acid the ultimate functional food component for disease prevention?', British Medical Journal, 328 211-214 (2004) [C1]
2004Lucock M, 'Science, medicine, and the future: Is folic acid the ultimate functional food component for disease prevention?', British Medical Journal, 328 211-214 (2004)
2003Yates Z, Lucock M, 'Interaction between common folate polymorphisms and B-vitamin nutritional status modulates homocysteine and risk for a thrombotic event', MOLECULAR GENETICS AND METABOLISM, 79 201-213 (2003) [C1]
2003Lucock MD, Yates ZR, Glanville T, Leeming R, Simpson N, Daskalakis I, 'A critical role for B-vitamin nutrition in human developmental and evolutionary biology', Nutrition Research, 23 1463-1475 (2003) [C1]
2002Lucock M, Yates Z, 'Measurement of red blood cell methylfolate', LANCET, 360 1021-1022 (2002) [C1]
2002Lucock M, Yates Z, Hall K, Leeming R, Rylance G, MacDonald A, Green A, 'The impact of phenylketonuria on folate metabolism', Molecular Genetics and Metabolism, 1096-7206 (2002) [C1]
2002Yates Z, Lucock M, 'Methionine synthase, polymorphism A2756G is associated with susceptibility for thromboembolic events and altered B vitamin/thiol metabolism', HAEMATOLOGICA, 87 751-756 (2002) [C1]
2002Lucock M, Yates Z, Hall K, Leeming R, Rylance G, MacDonald A, Green A, 'The impact of phenylketonuria on folate metabolism', MOLECULAR GENETICS AND METABOLISM, 76 305-312 (2002) [C1]
2002Lucock M, Yates Z, 'Correspondence: Measurement of red blood cell methylfolate', Lancet, 360 (2002) [C3]
2001Lucock M, Daskalakis I, Yates Z, 'C677T MTHFR genotypes show graded response to vitamin B-12 dependent regeneration of tetrahydrofolate, the main congener of all cellular folates', NUTRITION RESEARCH, 21 1357-1362 (2001) [C1]
2001Lucock M, Daskalakis I, Hinkins M, Yates Z, 'An examination of polymorphic genes and folate metabolism in mothers affected by a spina bifida pregnancy', MOLECULAR GENETICS AND METABOLISM, 73 322-332 (2001) [C1]
2001Lucock M, Daskalakis I, Hinkins M, Yates Z, 'An examination of polymorphic genes and folate metabolism in mothers affected by a spina bifida pregnancy', Molecular Genetics and Metabolism, 1096-7206 (2001) [C1]
2001Lucock M, Yates Z, Daskalakis I, 'C677T MTHFR genotypes show graded response to vitamin B12 dependent regeneration of tetrahydrofolate, the main congenor of all cellular folates', Nutrition Research, 0271-5317 (2001) [C1]
2000Lucock M, Daskalakis I, Briggs D, Yates Z, Levene M, 'Altered folate metabolism and disposition in mothers affected by a spina bifida pregnancy: Influence of 677c -> t methylenetetrahydrofolate reductase and 2756a -> g methionine synthase genotypes', MOLECULAR GENETICS AND METABOLISM, 70 27-44 (2000) [C1]
2000Lucock M, 'Folic acid: Nutritional biochemistry, molecular biology, and role in disease processes', MOLECULAR GENETICS AND METABOLISM, 71 121-138 (2000)
2000Lucock M, Daskalakis I, 'New perspectives on folate status: a differential role for the vitamin in cardiovascular disease, birth defects and other conditions', BRITISH JOURNAL OF BIOMEDICAL SCIENCE, 57 254-260 (2000)
1999Lucock MD, Daskalakis I, Schorah CJ, Lumb CH, Oliver M, Devitt H, et al., 'Folate-homocysteine interrelations: Potential new markers of folate status', MOLECULAR GENETICS AND METABOLISM, 67 23-35 (1999)
1998Schorah CJ, Devitt H, Lucock M, Dowell AC, 'The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study', EUROPEAN JOURNAL OF CLINICAL NUTRITION, 52 407-411 (1998)
1998Lucock MD, Daskalakis I, Lumb CH, Schorah CJ, Levene MI, 'Impaired regeneration of monoglutamyl tetrahydrofolate leads to cellular folate depletion in mothers affected by a spina bifida pregnancy', MOLECULAR GENETICS AND METABOLISM, 65 18-30 (1998)
1997Lucock MD, Wild J, Lumb CH, Oliver M, Kendall R, Daskalakis I, et al., 'Risk of neural tube defect-affected pregnancy is associated with a block in maternal one-carbon metabolism at the level of N-5-methyltetrahydrofolate:homocysteine methyltransferase', BIOCHEMICAL AND MOLECULAR MEDICINE, 61 28-40 (1997)
1996Schorah CJ, Wild J, Lucock M, 'Folate dose may mask small differences in folate metabolism', AMERICAN JOURNAL OF CLINICAL NUTRITION, 63 976-976 (1996)
1996Lucock MD, Daskalakis I, Schorah CJ, Levene MI, Hartley R, 'Analysis and biochemistry of blood folate', BIOCHEMICAL AND MOLECULAR MEDICINE, 58 93-112 (1996)
1996Lucock MD, Daskalakis IG, Wild J, Anderson A, Schorah CJ, Lean MEJ, Levene MI, 'The influence of dietary folate and methionine on the metabolic disposition of endotoxic homocysteine', BIOCHEMICAL AND MOLECULAR MEDICINE, 59 104-111 (1996)
1996Daskalakis I, Lucock MD, Anderson A, Wild J, Schorah CJ, Levene MI, 'Determination of plasma total homocysteine and cysteine using HPLC with fluorescence detection and an ammonium 7-fluoro-2,1,3-benzoxadiazole-4-sulphonate (SBD-F) derivatization protocol optimized for antioxidant concentration, derivatization reagent concentration, temperature and matrix pH', BIOMEDICAL CHROMATOGRAPHY, 10 205-212 (1996)
1995HABIBZADEH N, WILD J, LUCOCK MD, SCHORAH CJ, 'ONE-CARBON METABOLISM IN PREGNANCIES COMPLICATED BY NEURAL-TUBE DEFECTS', LANCET, 345 791-791 (1995)
1995LUCOCK MD, WILD J, LEVENE MI, 'ENZYME DEFECT AS A RISK FACTOR FOR SPINA-BIFIDA', LANCET, 346 1495-1496 (1995)
1995LUCOCK MD, GREEN M, LEVENE MI, 'METHYLFOLATE MODULATES POTASSIUM-EVOKED NEURO-SECRETION - EVIDENCE FOR A ROLE AT THE PTERIDINE COFACTOR LEVEL OF TYROSINE 3-HYDROXYLASE', NEUROCHEMICAL RESEARCH, 20 727-736 (1995)
1995WILD J, LUCOCK MD, SCHORAH CJ, 'PERICONCEPTIONAL FOLATE AND NEURAL-TUBE DEFECTS', AMERICAN JOURNAL OF CLINICAL NUTRITION, 61 615-616 (1995)
1995LUCOCK MD, GREEN M, PRIESTNALL M, DASKALAKIS I, LEVENE MI, HARTLEY R, 'OPTIMIZATION OF CHROMATOGRAPHIC CONDITIONS FOR THE DETERMINATION OF FOLATES IN FOODS AND BIOLOGICAL TISSUES FOR NUTRITIONAL AND CLINICAL-WORK', FOOD CHEMISTRY, 53 329-338 (1995)
1995LUCOCK MD, PRIESTNALL M, DASKALAKIS I, SCHORAH CJ, WILD J, LEVENE MI, 'NONENZYMATIC DEGRADATION AND SALVAGE OF DIETARY-FOLATE - PHYSICOCHEMICAL FACTORS LIKELY TO INFLUENCE BIOAVAILABILITY', BIOCHEMICAL AND MOLECULAR MEDICINE, 55 43-53 (1995)
1994LUCOCK MD, NAYEEMUDDIN FA, HABIBZADEH N, SCHORAH CJ, HARTLEY R, LEVENE MI, 'METHYLFOLATE EXHIBITS A NEGATIVE IN-VITRO INTERACTION WITH IMPORTANT DIETARY METAL-CATIONS', FOOD CHEMISTRY, 50 307-310 (1994)
1994LUCOCK MD, WILD J, SCHORAH CJ, LEVENE MI, HARTLEY R, 'THE METHYLFOLATE AXIS IN NEURAL-TUBE DEFECTS - IN-VITRO CHARACTERIZATION AND CLINICAL INVESTIGATION', BIOCHEMICAL MEDICINE AND METABOLIC BIOLOGY, 52 101-114 (1994)
1993LUCOCK MD, LEVENE MI, HARTLEY R, 'MODULATION OF POTASSIUM EVOKED SECRETORY FUNCTION IN RAT CEREBELLAR SLICES MEASURED BY REAL-TIME MONITORING - EVIDENCE OF A POSSIBLE ROLE FOR METHYLFOLATE IN CEREBRAL TISSUE', NEUROCHEMICAL RESEARCH, 18 617-623 (1993)
1993LUCOCK MD, GREEN M, HARTLEY R, LEVENE MI, 'PHYSICOCHEMICAL AND BIOLOGICAL FACTORS INFLUENCING METHYLFOLATE STABILITY - USE OF DITHIOTHREITOL FOR HPLC ANALYSIS WITH ELECTROCHEMICAL DETECTION', FOOD CHEMISTRY, 47 79-86 (1993)
1991HARTLEY R, GREEN M, LUCOCK MD, RYAN S, FORSYTHE WI, 'SOLID-PHASE EXTRACTION OF OXCARBAZEPINE AND ITS METABOLITES FROM PLASMA FOR ANALYSIS BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY', BIOMEDICAL CHROMATOGRAPHY, 5 212-215 (1991)
1991LUCOCK MD, WILD J, HARTLEY R, LEVENE MI, SCHORAH CJ, 'VITAMINS TO PREVENT NEURAL-TUBE DEFECTS', LANCET, 338 894-895 (1991)
1991HARTLEY R, FORSYTHE WI, MCLAIN B, NG PC, LUCOCK MD, 'DAILY VARIATIONS IN STEADY-STATE PLASMA-CONCENTRATIONS OF CARBAMAZEPINE AND ITS METABOLITES IN EPILEPTIC CHILDREN', CLINICAL PHARMACOKINETICS, 20 237-244 (1991)
1990HARTLEY R, LUCOCK MD, NG PC, FORSYTHE WI, MCLAIN B, BOWMER CJ, 'FACTORS INFLUENCING PLASMA-LEVEL DOSE RATIOS OF CARBAMAZEPINE AND ITS MAJOR METABOLITES IN EPILEPTIC CHILDREN', THERAPEUTIC DRUG MONITORING, 12 438-444 (1990)
1989LUCOCK M, WILD J, SMITHELLS R, HARTLEY R, 'BIOTRANSFORMATION OF PTEROYLMONOGLUTAMIC ACID DURING ABSORPTION - IMPLICATIONS OF MICHAELIS-MENTEN KINETICS', EUROPEAN JOURNAL OF CLINICAL NUTRITION, 43 631-635 (1989)
1989LUCOCK MD, WILD J, SMITHELLS RW, HARTLEY R, 'INVIVO CHARACTERIZATION OF THE ABSORPTION AND BIOTRANSFORMATION OF PTEROYLMONOGLUTAMIC ACID IN MAN - A MODEL FOR FUTURE STUDIES', BIOCHEMICAL MEDICINE AND METABOLIC BIOLOGY, 42 30-42 (1989)
1989LUCOCK MD, HARTLEY R, SMITHELLS RW, 'A RAPID AND SPECIFIC HPLC-ELECTROCHEMICAL METHOD FOR THE DETERMINATION OF ENDOGENOUS 5-METHYLTETRAHYDROFOLIC ACID IN PLASMA USING SOLID-PHASE SAMPLE PREPARATION WITH INTERNAL STANDARDIZATION', BIOMEDICAL CHROMATOGRAPHY, 3 58-63 (1989)
1987HARTLEY R, LUCOCK M, BECKER M, 'IMPROVED HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC PROCEDURE FOR THE DETERMINATION OF CHLORMETHIAZOLE LEVELS FOLLOWING SOLID-PHASE EXTRACTION FROM PLASMA', JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS, 415 357-364 (1987)
1987HARTLEY R, LUCOCK M, FORSYTHE WI, SMITHELLS RW, 'SOLID-PHASE EXTRACTION OF CARBAMAZEPINE AND 2 MAJOR METABOLITES FROM PLASMA FOR ANALYSIS BY HPLC', JOURNAL OF LIQUID CHROMATOGRAPHY, 10 2393-2409 (1987)
1987LUCOCK M, HARTLEY R, WILD NJ, 'HPLC DETERMINATION OF VITAMIN-K1 IN NEONATAL PLASMA FOLLOWING ORAL OR PARENTERAL SUPPLEMENTATION WITH KONAKION', JOURNAL OF LIQUID CHROMATOGRAPHY, 10 191-203 (1987)
1986PICKARD CE, STEWART AD, HARTLEY R, LUCOCK MD, 'A RAPID HPLC METHOD FOR MONITORING PLASMA-LEVELS OF CAFFEINE AND THEOPHYLLINE USING SOLID-PHASE EXTRACTION COLUMNS', ANNALS OF CLINICAL BIOCHEMISTRY, 23 440-446 (1986)
1986HARTLEY R, LUCOCK M, COOKMAN J, BECKER M, SMITH IJ, SMITHELLS RW, FORSYTHE WI, 'HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC DETERMINATION OF CARBAMAZEPINE AND CARBAMAZEPINE 10,11-EPOXIDE IN PLASMA AND SALIVA FOLLOWING SOLID-PHASE SAMPLE EXTRACTION', JOURNAL OF CHROMATOGRAPHY, 380 347-356 (1986)
1986HARTLEY R, LUCOCK M, BECKER M, SMITH IJ, FORSYTHE WI, 'SOLID-PHASE EXTRACTION OF ACETAZOLAMIDE FROM BIOLOGICAL-FLUIDS AND SUBSEQUENT ANALYSIS BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY', JOURNAL OF CHROMATOGRAPHY, 377 295-305 (1986)
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Conference (34 outputs)

YearCitationAltmetricsLink
2013Siow W, Niblett S, King K, Yates Z, Hampe T, Lucock M, Veysey M, 'Prevalence of non-alcoholic fatty liver disease in an elderly Australian population', JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2013) [E3]
2013Choi J, Siow W, Yates Z, Lucock M, Veysey M, 'Influence of synthetic folic acid concentration on Caco-2 cell growth', JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2013) [E3]
2013Veysey M, Siow W, Choi J-H, Martin C, Tang S, Yates ZR, Lucock M, 'A Bitter Taste Gene (P49a Variant of Tas2r38) Interacts With A1298c-MTHFR to Modify Risk for Adenomas in an Australian Population', GASTROENTEROLOGY, Orlando, FL (2013) [E3]
2013Siow W, Niblett S, King K, Yates Z, Martin C, Lucock M, Veysey M, 'A community-based study of dietary macro and micronutrients and the risk of colorectal cancer in an elderly Australian population', JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2013) [E3]
2011Naylor C, Lucock MD, Veysey MJ, Naumovski N, Boyd L, Dufficy L, et al., 'Folate nutritional genetics and degenerative disorders in the elderly with special reference to hypertension and depression', Australasian Medical Journal, Queenstown, NZ (2011) [E3]
2011Yates ZR, Kho J, Choi J-H, Boyd L, Ng X, Skinner V, et al., 'C776G TCNII genotype influences the relationship between blood vitamin B12 and cellular folate', Australasian Medical Journal, Queenstown, NZ (2011) [E3]
2011Choi J-H, Yates ZR, Boyd L, Veysey MJ, Lucock MD, 'Dietary folate vitamers as potential risk factors in the aetiology of adenomatous polyps', Australasian Medical Journal, Queenstown, NZ (2011) [E3]
2010Chang J, Lucock MD, Wai R, Boyd L, Ng X, Skinner VM, et al., 'Dietary folic acid, red cell folate and the risk of adenomatous polyps in an Australian population', Journal of Gastroenterology and Hepatology. Special Issue: Australian Gastroenterology Week 2010, Gold Coast, QLD (2010) [E3]
2009Veysey MJ, Boyd L, Wai R, Ng X, Skinner V, Tang S, et al., 'Preliminary data to support a relationship between taste genetics, folate status, folate genes and the development of colonic adenomas: A novel nutrigenomic circuit', Gastro 2009 UEGW/WCOG: Scientific Programme & EACCME, London, UK (2009) [E3]
2009Boyd L, Lucock MD, Wai R, Ng X, Yates ZR, Skinner V, et al., 'Folate status: A recognised determinant of colorectal neoplasia may be modified by bitter taste perception and genetics', Proceedings of the Nutrition Society of Australia, Newcastle, NSW (2009) [E3]
2008Ng X, Boyd L, Dufficy L, Naumovski N, Blades BL, Travers C, et al., 'Folate genes and risk for hypertension in an elderly population sample', 3rd Asia Pacific Nutrigenomics Conference: Conference Program & Information, Melbourne, VIC (2008) [E3]
2008Yates ZR, Lucock MD, 'Folate and the C677T-MTHFR variant: Impact on population health', Journal of Nutrigenetics and Nutrigenomics, Melbourne, VIC (2008) [E3]
2008Boyd L, Wai RKH, Ng X, King K, Skinner V, Roach PD, et al., 'A preliminary study to examine whether common folate polymorphisms are risk factors for the development of adenomatous polyps', Journal of Gastroenterology and Hepatology, Brisbane, QLD (2008) [E3]
2008Wai RKH, Boyd L, Ng X, King K, Skinner V, Roach PD, et al., 'Preliminary evidence that bitter taste perception can modify folate status: A recognised risk factor for colorectal neoplasia', Journal of Gastroenterology and Hepatology, Brisbane, QLD (2008) [E3]
2007Pengelly AR, Lucock MD, Roach PD, 'A method for assessing the variation in Flavonoid levels of Dodonaea viscosa subspecies Angustifolia, a traditional wound healing medicinal herb', 50 Years of the Phytochemical Society of Europe: Highlights in the Evolution of Phytochemistry. Abstract Book, Cambridge, U.K. (2007) [E3]

Co-authors: Paul Roach

2006Naumovski N, Roach PD, Blades BL, Lucock MD, Travers C, Lewis PR, et al., 'Homocysteine, vitamin B12 and folate in an elderly population sample', Heart Foundation Conference and Scientific Meeting, Sydney, NSW, Australia (2006) [E3]
2006Roach PD, Dufficy L, Naumovski N, Ng X, Blades BL, Travers C, et al., 'The association of dietary folate with serum and red cell folate is modulated by the G80A reduced folate carrier single nucloetide polymorphism in an elderly population sample', The Proceedings of the Nutrition Society of Australia, Sydney, NSW (2006) [E3]
2006Roach PD, Naumovski N, Blades BL, Lucock MD, Travers C, Lewis PR, et al., 'Serum vitamin B12 is inversely related to blood pressure and anxiety in elderly women but not in elderly men', Atherosclerosis Supplements, Rome, Italy (2006) [E3]
2006Blades BL, Naumovski N, Roach PD, Lucock MD, Travers C, Lewis PR, et al., 'Vitamin B12 is a better inverse correlate for homocysteine than folate in an elderly population sample', Atherosclerosis Supplements, Rome, Italy (2006) [E3]
2006Naumovski N, Blades BL, Lucock MD, Travers C, Lewis PR, Sturm J, Veysey MJ, 'Serum vitamin B12 is inversely related to blood pressure and anxiety in women but not men in an elderly population sample', Heart Foundation Conference and Scientific Meeting, Sydney, NSW, Australia (2006) [E3]

Co-authors: Martin Veysey

2006Roach PD, Dufficy L, Naumovski N, Ng X, Blades BL, Travers C, et al., 'The association of blood pressure with dietary folate in elderly females and its modulation by the G80A reduced folate carrier SNP', Program & Abstracts Australian Atherosclerosis Society, Couran Cove Island, Queensland (2006) [E3]
2005Roach PD, Blades BL, Lucock MD, Naumovski N, Dufficy L, Lewis (Ext) PR, et al., 'Serum Vitamin B12 is Inversely Related to Blood Pressure in Women but not Men in an Elderly Population Sample', Proceedings of Annual Scientific Meeting 2005, Darwin, NT (2005) [E3]
2005Roach PD, Naumovski N, Dufficy L, Lucock MD, Blades BL, Lewis (Ext) PR, et al., 'Folate, viamin B12, plasma thiols and cognitive funciton in an elderly population sample', Asia Pacific Journal of Clinical Nutrition, Melbourne, Victoria (2005) [E3]
2004Moskovitz DN, Sohn KJ, Smirnakis F, Novakovic P, Yates ZR, Lucock MD, et al., 'Effects of folylpolyglutamyl synthetase modulation on chemosensitivity of colon cancer cells to 5 fluorouracil and methotrexate', CDDW Abstracts, Canada (2004) [E3]

Co-authors: Zoe Yates

2004Novakovic P, Sohn KJ, Chiang EP, Dickhout J, Yates Z, Lucock M, et al., 'Effect of MTHFR C677T polymorphism on the intracellular methionine cycle and DNA methylation in colon cancer cells', FASEB JOURNAL, Washington, DC (2004)
2003Glanville T, Yates Z, Hopkins S, Walker JJ, Lucock M, Simpson N, 'Growth restriction is associated with fetal carriage of A66G methionine synthase reductase SNP', AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, NEW ORLEANS, LOUISIANA (2003) [E1]
2002Lucock M, Yates Z, Goodall E, Achilli G, '12 Channel coulometric electrochemical detection for the identification of polyglutamate homology amongst cellular folates', Boston (2002) [E1]
2002Glanville T, Yates Z, Ovadia L, Walker JJ, Lucock M, Simpson N, 'Folate gene MTHFR C677T polymorphism and fetal growth restriction', Journal of Obstetrics and Gynaecology, 22(Supp1) S31-S32 (2002) [E1]
2002Lucock M, Yates Z, Cade A, 'Gastro intestinal pH modulates facile interconvertion of native formylfolates during absorption', Boston (2002) [E1]
2002Yates Z, Lucock M, 'C677T MTHFR Genotype is a Risk Factor for Thromboembolism: Comparison of T Allele Frequency and Homocysteine Level between Female Thromboembolic and Non-Thromboembolic Vascualr Patients, NTD Mother and Matched NTD Controls', Boston (2002) [E1]
1997Lucock MD, Daskalakis IG, Lumb C, Oliver M, Wild J, Schorah C, Levene MI, 'One carbon metabolic parameters and NTD.', CHEMISTRY AND BIOLOGY OF PTERIDINES AND FOLATES 1997, BERCHTESGADEN, GERMANY (1997)
1997Lucock MD, Lumb C, Wild J, Oliver M, Daskalakis I, Schorah C, et al., 'Elevated homocysteine in subjects with a previous NTD pregnancy is associated with increased hexaglutamyl methylfolate consistent with impaired B-12 dependent methionine synthase activity.', CHEMISTRY AND BIOLOGY OF PTERIDINES AND FOLATES 1997, BERCHTESGADEN, GERMANY (1997)
1997Lucock MD, Lumb C, Wild J, Oliver M, Daskalakis I, Schorah CJ, et al., 'Methionine synthase activity is dependent upon intracellular methylfolate level in control but not NTD subjects where utilization of hexaglutamyl methylfolate is limiting for remethylation of homocysteine.', CHEMISTRY AND BIOLOGY OF PTERIDINES AND FOLATES 1997, BERCHTESGADEN, GERMANY (1997)
1997Lucock MD, Lumb C, Wild J, Daskalakis I, Schorah CJ, Kendall R, Levene MI, 'Methyl group utilization versus production in NTD and control subjects: Influence of vitamin B-12', CHEMISTRY AND BIOLOGY OF PTERIDINES AND FOLATES 1997, BERCHTESGADEN, GERMANY (1997)
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Grants and Funding

Summary

Number of grants15
Total funding$957,034

- Indicates that the researcher may be seeking students for this project.

Click on a grant title below to expand the full details for that specific grant.

2012 (1 grants)

Phase I and II detoxification genes; the correlation of epigenetic modifications with nutritional status, lifestyle factors, health and disease$21,000
Funding Body: CSIRO - Energy Technology

Project Team
Associate Professor Mark Lucock, Associate Professor Martin Veysey, Doctor Zoe Yates, Ms Emma Beckett, Dr Konsta Duesing
SchemeRole
Postgraduate Research ScholarshipChief Investigator
Total AmountFunding StartFunding Finish
$21,00020122015
GNo:G1200845

2010 (1 grants)

Is retirement village living good for health: Comparing the health of older adults living in retirement villages and the community$36,364
Funding Body: Valhalla Village Pty Ltd

Project Team
Associate Professor Martin Veysey, Dr Peter Lewis, Associate Professor Mark Lucock, Doctor Paul Roach, Dr David Kennedy
SchemeRole
Linkage Projects Partner fundingInvestigator
Total AmountFunding StartFunding Finish
$36,36420102011
GNo:G1000936

2009 (1 grants)

The Association between Folate Nutritional Status and Folate Gene Polymorphisms in an Elderly Australian Population$61,281
Funding Body: Central Coast Local Health District

Project Team
Associate Professor Martin Veysey, Doctor Zoe Yates, Associate Professor Mark Lucock, Doctor Paul Roach
SchemeRole
Research Sponsorship ScholarshipInvestigator
Total AmountFunding StartFunding Finish
$61,28120092011
GNo:G0190658

2008 (4 grants)

Is retirement village living good for health: Comparing the health of older adults living in retirement villages and the community$390,173
Funding Body: ARC (Australian Research Council)

Project Team
Associate Professor Martin Veysey, Dr Peter Lewis, Associate Professor Mark Lucock, Doctor Paul Roach, Dr David Kennedy
SchemeRole
Linkage ProjectsInvestigator
Total AmountFunding StartFunding Finish
$390,17320082010
GNo:G0188386

Is retirement village living good for health: Comparing the health of older adults living in retirement villages and the community$162,000
Funding Body: Central Coast Local Health District

Project Team
Associate Professor Martin Veysey, Dr Peter Lewis, Associate Professor Mark Lucock, Doctor Paul Roach, Dr David Kennedy
SchemeRole
Linkage Projects Partner fundingInvestigator
Total AmountFunding StartFunding Finish
$162,00020082014
GNo:G0188995

Is retirement village living good for health: Comparing the health of older adults living in retirement villages and the community$85,000
Funding Body: UnitingCare Ageing NSW.ACT

Project Team
Associate Professor Martin Veysey, Dr Peter Lewis, Associate Professor Mark Lucock, Doctor Paul Roach, Dr David Kennedy
SchemeRole
Linkage Projects Partner fundingInvestigator
Total AmountFunding StartFunding Finish
$85,00020082010
GNo:G0189230

Is retirement village living good for health: Comparing the health of older adults living in retirement villages and the community$15,000
Funding Body: Urbis Pty Ltd

Project Team
Associate Professor Martin Veysey, Dr Peter Lewis, Associate Professor Mark Lucock, Doctor Paul Roach, Dr David Kennedy
SchemeRole
Linkage Projects Partner fundingInvestigator
Total AmountFunding StartFunding Finish
$15,00020082010
GNo:G0189232

2007 (2 grants)

The role of folic acid nutritional genetics in common chronic degenerative disorders$29,424
Funding Body: Central Coast Local Health District

Project Team
Associate Professor Mark Lucock, Mrs Lyndell Boyd
SchemeRole
Research Sponsorship ScholarshipChief Investigator
Total AmountFunding StartFunding Finish
$29,42420072009
GNo:G0187843

Maternal probiotic treatment protects against colonic and immune dysfunctions induced by neonatal stress$10,664
Funding Body: University of Newcastle

Project Team
Professor Deborah Hodgson, Doctor Michelle Adams, Associate Professor Mark Lucock
SchemeRole
Pilot GrantInvestigator
Total AmountFunding StartFunding Finish
$10,66420072007
GNo:G0187857

2005 (3 grants)

2005 RIBG allocation$31,000
Funding Body: University of Newcastle

Project Team
Associate Professor Mark Lucock
SchemeRole
Research Infrastructure Block Grant (RIBG)Chief Investigator
Total AmountFunding StartFunding Finish
$31,00020052005
GNo:G0185844

Vitamin B12 and Autism$10,000
Funding Body: University of Newcastle

Project Team
Doctor Michelle Adams, Associate Professor Mark Lucock
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$10,00020052005
GNo:G0184636

Central Coast Vascular Health in Retirement Village Residents Study, Phase 1$9,044
Funding Body: University of Newcastle

Project Team
Associate Professor Martin Veysey, Associate Professor Mark Lucock
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$9,04420052005
GNo:G0184680

2004 (2 grants)

PhD - Physio-chemical properties and genetic factors that influence folic acid bioavailability and metabolism: Implications in health and disease$66,084
Funding Body: Central Coast Health Teaching & Research Unit

Project Team
Associate Professor Mark Lucock, Miss Xiaowei Ng
SchemeRole
Postgraduate Research ScholarshipChief Investigator
Total AmountFunding StartFunding Finish
$66,08420042007
GNo:G0184604

Vitamin B12 and gene interactions in autism$20,000
Funding Body: Hunter Children`s Research Foundation

Project Team
Doctor Michelle Adams, Associate Professor Mark Lucock, Conjoint Associate Professor John Stuart
SchemeRole
Research GrantInvestigator
Total AmountFunding StartFunding Finish
$20,00020042004
GNo:G0184142

2003 (1 grants)

B-vitamin nutrition and genetics in degenerative and development disorders: A study of nutrient-nutrient, nutrient-gene and gene-gene interactions$10,000
Funding Body: University of Newcastle

Project Team
Associate Professor Mark Lucock
SchemeRole
New Staff GrantChief Investigator
Total AmountFunding StartFunding Finish
$10,00020032003
GNo:G0183548
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Research Supervision

Number of current supervisions5
Total current UoN PhD EFTSL0.6

For supervisions undertaken at an institution other that the University of Newcastle, the institution name is listed below the program name.

Current Supervision

CommencedProposed
Completion
ProgramSupervisor TypeResearch Title
20122016PhD (Food Science)Principal SupervisorThe Association of MIRNA Profiles and DNA Methylation with Micronutrient Intake & Status
20102014PhD (Food Science)Co-SupervisorGenotype-Phenotype Relationships Relevant to the Lifecycle with Special Reference to Vitamin Nutrition
20072010PHD Food Science & Biotechnology
University of Newcastle
Co-SupervisorThe role of folic acid nutritional genetics in common chronic degenerative disorders
20042007PHD Food Science & Biotechnology
University of Newcastle
Principal SupervisorPhysico-chemical Properties and Genetic Factors that influence the Bioavailability and Metabolism of Folic Acid: Implications in Health and Disease
20032007PHD Food Science & Biotechnology
University of Newcastle
Co-SupervisorInvestigation of Anti-inflammatory Properties in Dodonaea Species

Past Supervision

YearProgramSupervisor TypeResearch Title
2014PhD (Food Science)Co-SupervisorIn Vitro and In Vivo Approaches to the Examination of Folate-Related Nutritional Genetics in Health and Disease
2014PhD (Food Science)Principal SupervisorThe Role of Folic Acid Related Nutritional Genetics in Common Chronic Degenerative Disorders
2009PhD (Food Science)Principal SupervisorPhysico-Chemical Properties and Genetic Factors That Influence the Bioavailability and Metabolism of Folic Acid: Implications in Health and Diseases
2009PhD (Food Science)Co-SupervisorFlavonoid Profile and Bioactivity of Dodonaea Viscosa (Australian Hop Bush) - An Indigenous Shrub
2008PhD (Food Science)Co-SupervisorThe Effect of Temperature Management on the Quality of Broccoli and Table Grapes Exported from Australia
2007Honours Food Science & Biotechnology
University of Newcastle
Co-SupervisorTHE EFFECT OF NUTRITION AND GENETIC VARIANTS OF VITAMIN B12 METABOLISM ON BIOCHEMICAL AND CLINICAL PHENOTYPE IN AN ELDERLY POPULATION
2007Honours Food Science & Biotechnology
University of Newcastle
Co-SupervisorThe effect of temperature on (-)-epigallochatechin gallate, the major catechin in green tea
2007PhD (Food Science)Co-SupervisorOptimisation Of Polysaccharides from Echinacea Purpurea
2005Honours Food Prcessing Technology
University of Newcastle
Co-SupervisorDoes the G80A reduced folate carrier variant alter the cellular level of folate and as a consequence plasma homocysteine, and is this influenced by folate intake
2005Honours Food Science & Biotechnology
University of Newcastle
Co-SupervisorIs cognitive function related to plasma thiol disposition in an elderly population
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Associate Professor Mark Lucock

Work Phone(02) 4348 4109
Fax(02) 4348 4145
Email
PositionAssociate Professor
Human Molecular Nutrition
School of Environmental and Life Sciences
Faculty of Science and Information Technology
The University of Newcastle, Australia
Focus AreaApplied Sciences
Office
E1.25,
Science Offices,
Ourimbah
10 Chittaway Road
Ourimbah NSW 2258
Australia
URL:www.newcastle.edu.au/profile/mark-lucock