Staff Profile
Conjoint Professor Margaret Dunkley
Conjoint Professor
School of Biomedical Sciences and Pharmacy
EditCareer Summary
Biography
I have worked within the University of Newcastle environment for 30 years. Initially I was employed on NHMRC research grants and was the Chief investigator on some of these. The focus of my research has been investigation of immune responses to infectious diseases at mucosal surfaces (lung, intestine, and reproductive tract), and development of effective mucosal vaccines. I am also a member of the VIVA group within the Hunter Medical Research Institute. For the past 15 years I have been employed by small biotech companies that have had their R&D units embedded within the University of Newcastle. In my industry role I have successfully obtained government AUS-Industry R&D grants.
Currently, as a Conjoint Associate Professor in School of Biomedical Sciences and Pharmacy, Faculty of Health, I lecture to Biomedical Sciences students, supervise post-graduate students, and collaborate on research projects within the Discipline of Immunology and Microbiology. I also Chair the University of Newcastle Biosafety Committee and I am a Vice Chancellor nominated employer representative member of the University OH&S committee. I am employed by Newcastle Innovation to work as the Chief Scientific Officer for Hunter Immunology Ltd (an unlisted public company) and I am responsible for the operation of the Hunter Immunology Ltd R&D Unit which is located within the School of Biomedical Science and Pharmacy in the David Maddison Clinical Sciences Building. In this role I also interact with manufacturing and pre-clinical and clinical research contractors. The focus of Hunter Immunology Ltd is vaccine development.
Qualifications
- PhD (Pathology), University of Newcastle, 31/12/1991
- Master of Business Administration, La Trobe University, 31/12/2004
- Graduate Diploma of Managment (Tech Management), Deakin University, 31/12/2001
- Graduate Certificate of Management (Tech Mgt), Deakin University, 31/12/2000
- Master of Science, University of Melbourne, 31/12/1975
- Bachelor of Science (Biochemistry)(Honours), University of Melbourne, 31/12/1971
Research
Research keywords
- Clinical trials
- Immunology
- Infectious diseases
- Vaccine
Research expertise
Research into immune mechanisms for protection against infectious disease and development of vaccines using both animal models and human clinical trials
Fields of Research
| Code | Description | Percentage |
|---|
| 110300 | Clinical Sciences | 40 |
| 110799 | Immunology Not Elsewhere Classified | 40 |
| 110899 | Medical Microbiology Not Elsewhere Classified | 20 |
Collaboration
Vaccine Development, Infectious Disease, Immunology
Administrative
Administrative expertise
Chair Insititutional Biosafety Committee for University of Newcastle, have completed MBA (Technology management), manage research and development programs for industry
Teaching
Teaching keywords
- Clinical trials
- Immunology
- Infectious diseases
- Product development
- Quality assurance
Teaching expertise
Teach in areas of immunology, infectious disease, development of products (such as vaccines, diagnostic kits) and regulatory requirements, clinical trials and quanity control and quality assurance
EditPublications
No publications.
EditGrants and Funding
Summary
| Number of grants | 18 |
|---|
| Total funding | $1,289,755 |
|---|
For project grants received where the lead institution is other than the University of Newcastle, details are shown in italics.
- Indicates that the researcher may be seeking students for this project.
Click on a grant title below to expand the full details for that specific grant.
2007 (1 grants)
Elucidation of the association between Haemophilus influenzae infection and neutrophilic asthma.$20,000
Funding Body: Hunter Medical Research Institute
2004 (2 grants)
Vaccine for oral, vaginal and systemic candidiasis$250,000
Funding Body: Biotechnology innovation fund (AUS-industry)
| Scheme | Role |
|---|
|
| Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $250,000 | 2004 | 2005 |
| GNo:17797989 |
Vaccine for oral, vaginal and systemic candidiasis$100,000
Funding Body: DSRD
| Scheme | Role |
|---|
| Top-up grant for successful BIF grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $100,000 | 2004 | 2004 |
| GNo:17798052 |
2003 (2 grants)
Therapeutic Oral Vaccine for Bronchitis$250,000
Funding Body: Biotechnology Innovation Fund (AUS-Industry)
| Scheme | Role |
|---|
|
| Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $250,000 | 2003 | 2004 |
| GNo:17797826 |
Therapeutic Oral vaccine for Bronchitis$100,000
Funding Body: DSRD
| Scheme | Role |
|---|
| Top-up grant for successful BIF grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $100,000 | 2003 | 2004 |
| GNo:17797868 |
2002 (1 grants)
Effects of early life exposure to bacteria on resistance to respiratory infection in adulthood$10,000
Funding Body: University of Newcastle
2001 (1 grants)
Evaluation of soluble H. influenzae and P. aeruginosa antigen preparations for protection against respiratory infection.$12,000
Funding Body: University of Newcastle
2000 (1 grants)
Options for the control of influenza IV Hersonissos, Crete, Greece 23-28 September 2000.$2,400
Funding Body: University of Newcastle
1999 (1 grants)
29th Annual Conference of the Australasian Society for Immunology Dunedin, New Zealand.$1,138
Funding Body: University of Newcastle
1998 (2 grants)
Dual influenza/bacteria respiratory infection - effect on the host immune response$200,556
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team |
|---|
| Conjoint Professor Margaret Dunkley, Emeritus Professor Robert Clancy |
| Scheme | Role |
|---|
| Project Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $200,556 | 1998 | 2000 |
| GNo:G0177162 |
Testing the efficacy of an oral Pseudomonas aeruginosa vaccine in the Cystic Fibrosis mouse.$17,000
Funding Body: University of Newcastle
1997 (3 grants)
Bacterial respiratory infection - immune elimination and viral interaction$62,193
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team |
|---|
| Conjoint Professor Margaret Dunkley, Assoc. Prof A Cripps, Emeritus Professor Robert Clancy |
| Scheme | Role |
|---|
| Project Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $62,193 | 1997 | 1997 |
| GNo:G0176232 |
EPICS Elite Flow Cytometer$60,000
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team |
|---|
| Conjoint Professor Kenneth Beagley, Professor Gordon Burns, Conjoint Professor Margaret Dunkley, Emeritus Professor Robert Clancy |
| Scheme | Role |
|---|
| Equipment Grant | Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $60,000 | 1997 | 1997 |
| GNo:G0176352 |
Is immunisation protective in an immunocompromised state?$15,000
Funding Body: ARC (Australian Research Council)
| Project Team |
|---|
| Conjoint Professor Kenneth Beagley, Conjoint Professor Margaret Dunkley, Conjoint Associate Professor Michael Boyle |
| Scheme | Role |
|---|
| Small Grant | Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $15,000 | 1997 | 1997 |
| GNo:G0176714 |
1996 (1 grants)
Determination of an immune pathogenesis for recurrent thrush in women$12,000
Funding Body: University of Newcastle
| Project Team |
|---|
| Emeritus Professor Robert Clancy, Dr Gerald Pang, Conjoint Professor Margaret Dunkley |
| Scheme | Role |
|---|
| Project Grant | Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $12,000 | 1996 | 1996 |
| GNo:G0175802 |
1995 (1 grants)
8th Intern. Congress of Mucosal Immunology, USA, 16-20 July$1,466
Funding Body: University of Newcastle
1994 (2 grants)
94,95,96 GRANT. Mucosal immunity to pathogenic bacteria in the lung.$174,282
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team |
|---|
| Assoc. Prof A Cripps, Conjoint Professor Margaret Dunkley, Emeritus Professor Robert Clancy |
| Scheme | Role |
|---|
| Project Grant | Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $174,282 | 1994 | 1995 |
| GNo:G0173012 |
American Lung Assoc/American Thoracic Soc Int Conference - Boston - 21-25 May 1994$1,720
Funding Body: University of Newcastle
EditResearch Supervision
| Number of current supervisions | 0 |
|---|
For supervisions undertaken at an institution other that the University of Newcastle, details are shown in italics, and the institution name is listed below the program name.
Past Supervision
| Year | Program | Supervisor Type | Research Title |
|---|
| 2008 | PhD (Behavioural Science) | Principal Supervisor | A Journey Past the Sun - Group Art Psychotherapy for People with Melanoma: An Investigation Using Narrative and Immunological and Psychosocial Measures |
| 2007 | Honours Microbiology
University of Newcastle | Principal Supervisor | Haemophilus influenzae in neutrophilic asthma model (Ama-Tawiah Essilfie) |
| 2003 | Honours Microbiology
University of Newcastle | Sole Supervisor | Evaluation of soluble Pseudomonas aeruginosa antigen preparations for protection against respiratory infection (Angela Ferguson) |
| 2002 | PHD Microbiology
University of Canberra | Co-Supervisor | Pseudomonas aeruginosa: Development of a mucosal vaccine for respiratory infection (Linda Thomas) |
| 1999 | Honours Microbiology
University of Newcastle | Sole Supervisor | Host defence mechanisms in respiratory Pseudomonas aeruginosa infection (Daphne Sawlwin) |
| 1999 | Honours Microbiology
University of Newcastle | Sole Supervisor | The role of antibody in protection against acute respiratory infection with Pseudomonas aeruginosa (Amanda McCue) |
