Staff Profile

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Career Summary

Biography

Dr Baines is a post doctoral researcher in the Department of Respiratory and Sleep Medicine, Hunter Medical Research Institute, and the Priority Research Centre for Asthma and Respiratory Disease. Her second 3 year post-doctoral fellowship commenced in January 2012 through The University of Newcastle, and prior to this she received a research fellowship through (2008-11) funded through Xstrata Coal and HMRI. As an early career post doctoral researcher; Dr Baines manages a semi independent molecular mechanisms group within Professor Peter Gibson’s laboratory.

Dr Baines interest in respiratory medicine began when she commenced PhD studies in late 2003 (awarded in 2008), on molecular mechanisms involved in the pathogenesis of noneosinophilic asthma, particularly involving neutrophils. Throughout her PhD she was supported with scholarships from The Asthma Foundation of NSW and the Asthma CRC. Dr Baines is committed to furthering a full-time career in medical research. Her research interests surround the role of gene-environment interactions in the development and pathogenesis of respiratory diseases including asthma and COPD. Dr Baines research uses high throughput genomics technologies to understand more about molecular mechanisms, particularly phenotype definition, biomarker identification and the relationship of phenotypes to clinical outcomes and treatment responses. She is also interested in how respiratory disease phenotypes evolve over time, with regard to the impact of medication use such as inhaled corticosteroids and macrolides, and environmental exposures such as diet and microbial infection.

Dr Baines research has led to a number of important contributions to the knowledge base particularly the role of neutrophils and gene expression in asthma and COPD. She has shown that airway neutrophils have an impaired innate immune response in asthma; however blood neutrophils are activated in the neutrophilic phenotype of asthma which is associated with systemic inflammation, a key feature of this phenotype. Dr Baines has defined transcriptional phenotypes of asthma using gene expression profiling of induced sputum and blood, proving the existence of phenotypes as well as the involvement of specific pathways (IL1 and TNF) in the pathogenesis of neutrophilic airway inflammation. Dr Baines has recently identified novel immune genes that are associated with rhinovirus infection of airway epithelial cells in COPD. Since 2009 Dr Baines has published >15 journal articles in highly ranked journals (Thorax, ERJ, JACI), that have been cited 138 times at present. She also has 2 book chapters, 1 Australian Provisional Patent and >38 conference abstracts.

Dr Baines has obtained several awards, including the New and Emerging Researcher Awards in 2011 from the Australian Lung Foundation and the Thoracic Society of Australia and New Zealand. She has been awarded 7 competitive travel grant awards, including the esteemed Janet Elder Travel Grant in 2011 and the HMRI Pulse Education Prize in 2010.

Dr Baines currently co-supervises 3 PhD students, and was primary supervisor to an honours student who received Class 1 honours in 2012. She is committed to providing a supportive environment for students to grow and learn the skills that will allow them to be successful in their independent research in the future.

Qualifications

  • PhD, University of Newcastle, 13/03/2008
  • Bachelor of Biomedical Sciences (Hons), University of Newcastle, 13/12/2002
  • Bachelor of Biomedical Sciences, University of Newcastle, 05/12/2001

Research

Research keywords

  • Asthma
  • COPD
  • Epigenetics
  • Gene Expression
  • Inflammation
  • Innate Immunity
  • Neutrophils

Research expertise

Katie is a laboratory based researcher with expertise in many laboratory methods, including using molecular techniques to understand more about the pathogenesis of respiratory diseases, including asthma and chronic obstructive pulmonary disease (COPD). She has particularl interest in using transcriptomics to understand how environmental influences in predisposed individuals can lead to the development of respiratory disease and different phenotypes of disease. She is also particularly interested in the role of inflammatory cells especially neutrophils in asthma and COPD, and the effects of environmental exposures including medications, diet and infection.

Languages

  • English

Fields of Research

CodeDescriptionPercentage
110203Respiratory Diseases100

Collaboration

Dr Baines is involved in several successful collaborations, both locally and nationally.

1. Prof Anne Chang, Menzies School of Health and University of Queensland: A new multi-site study investigating airway and systemic markers and mechanisms of Protracted Bacterial Bronchitis in children. Subject of an NHMRC funded grant 2013-2016

2. Dr Manuel Ferreira, University of Queensland: Characterisation of the asthma transcriptome using RNA-seq. Subject of a UQ Collaborative Seed Funding Grant 2012.

3. Dr Brian Oliver and Prof Dominik Hartl, Woolcock Research Institute, University of Sydney, and University of Tubingen, Germany. Neutrophil responses to rhinovirus infection in asthma. Subject of a pending NHMRC grant for 2014.

Local collaborations:

1. Prof Peter Gibson and Dr Jodie Simpson: Markers and Mechanisms of severe asthma inflammatory phenotypes. Subject of a NHMRC grant 2013-2015.

2. Dr Vanessa McDonald and Prof Peter Gibson: Phenotype based management of severe asthma. Funded by HMRI and John Hunter Hospital Charitable Trust 2012.

2. Dr Lisa Wood: Effects of diet, including antioxidant withdrawal and fatty acids on gene expression in asthma.

3. A/Prof Peter Wark: Rhinovirus infection and changes in gene expression in primary bronchial epithelial cells in COPD and asthma.

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Publications

For publications that are currently unpublished or in-press, details are shown in italics.

Click on a category title below to expand the list of citations for that specific category.

Chapter (1 outputs)

YearCitationAltmetricsLink
2009Simpson JL, Baines KJ, Gibson PG, 'Biology of neutrophils', Middleton's Allergy: Principles & Practice, Mosby, Philadelphia, Pennsylvania 283-294 (2009) [B1]

Journal article (25 outputs)

YearCitationAltmetricsLink
2014Gunawardhana LP, Gibson PG, Simpson JL, Powell H, Baines KJ, 'Activity and expression of histone acetylases and deacetylases in inflammatory phenotypes of asthma', CLINICAL AND EXPERIMENTAL ALLERGY, 44 47-57 (2014) [C1]
2014Simpson JL, Phipps S, Baines KJ, Oreo KM, Gunawardhana L, Gibson PG, 'Elevated expression of the NLRP3 inflammasome in neutrophilic asthma', European Respiratory Journal, 43 1067-1076 (2014)
2014Gunawardhana LP, Baines KJ, Mattes J, Murphy VE, Simpson JL, Gibson PG, 'Differential DNA methylation profiles of infants exposed to maternal asthma during pregnancy.', Pediatr Pulmonol, 49 852-862 (2014)
2014Simpson JL, Powell H, Baines KJ, Milne D, Coxson HO, Hansbro PM, Gibson PG, 'The effect of azithromycin in adults with stable neutrophilic COPD: a double blind randomised, placebo controlled trial.', PLoS One, 9 e105609 (2014)
2014Baines KJ, Pavord ID, Gibson PG, 'The role of biomarkers in the management of airways disease.', Int J Tuberc Lung Dis, 18 1264-1268 (2014)
2014Simpson JL, Baines KJ, Ryan N, Gibson PG, 'Neutrophilic asthma is characterised by increased rhinosinusitis with sleep disturbance and GERD.', Asian Pac J Allergy Immunol, 32 66-74 (2014)
2014Gunawardhana LP, Gibson PG, Simpson JL, Benton MC, Lea RA, Baines KJ, 'Characteristic DNA methylation profiles in peripheral blood monocytes are associated with inflammatory phenotypes of asthma.', Epigenetics, 9 1302-1316 (2014)
2014Baines KJ, Simpson JL, Wood LG, Fibbens NL, Powell H, Gibson PG, et al., 'Sputum gene expression signature of 6 biomarkers discriminates asthma inflammatory phenotypes', Journal of Allergy and Clinical Immunology, (2014)
2014Oreo KM, Gibson PG, Simpson JL, Wood LG, McDonald VM, Baines KJ, 'Sputum ADAM8 expression is increased in severe asthma and COPD', CLINICAL AND EXPERIMENTAL ALLERGY, 44 342-352 (2014)
2013Fu J-J, Baines KJ, Wood LG, Gibson PG, 'Systemic Inflammation Is Associated with Differential Gene Expression and Airway Neutrophilia in Asthma', OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY, 17 187-199 (2013) [C1]
2013Simpson JL, McDonald VM, Baines KJ, Oreo KM, Wang F, Hansbro PM, Gibson PG, 'Influence of Age, Past Smoking, and Disease Severity on TLR2, Neutrophilic Inflammation, and MMP-9 Levels in COPD', MEDIATORS OF INFLAMMATION, (2013) [C1]
2013Kaiko GE, Loh Z, Spann K, Lynch JP, Lalwani A, Zheng Z, et al., 'Toll-like receptor 7 gene deficiency and early-life Pneumovirus infection interact to predispose toward the development of asthma-like pathology in mice', JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 131 1331-U132 (2013) [C1]
2013Baines KJ, Hsu AC-Y, Tooze M, Gunawardhana LP, Gibson PG, Wark PAB, 'Novel immune genes associated with excessive inflammatory and antiviral responses to rhinovirus in COPD', RESPIRATORY RESEARCH, 14 (2013) [C1]
2013Murphy VE, Mattes J, Powell H, Baines KJ, Gibson PG, 'Respiratory viral infections in pregnant women with asthma are associated with wheezing in the first 12 months of life', Pediatric Allergy and Immunology, (2013)
2012Wood LG, Baines KJ, Fu J, Scott HA, Gibson PG, 'The neutrophilic inflammatory phenotype is associated with systemic inflammation in asthma', Chest, 142 86-93 (2012) [C1]
2012Simpson JL, Phipps S, Baines KJ, Oreo KM, Gibson PG, 'NALP3 INFLAMMASOME ACTIVATION IN NEUTROPHILIC ASTHMA', RESPIROLOGY, 17 2-2 (2012) [E3]
2011Wang F, He XY, Baines KJ, Gunawardhana LP, Simpson JL, Li F, Gibson PG, 'Different inflammatory phenotypes in adults and children with acute asthma', European Respiratory Journal, 38 567-574 (2011) [C1]
2011Baines KJ, Simpson JL, Wood LG, Scott R, Gibson PG, 'Systemic upregulation of neutrophil a-defensins and serine proteases in neutrophilic asthma', Thorax, 66 942-947 (2011) [C1]
2011Baines KJ, Simpson JL, Wood LG, Scott R, Gibson PG, 'Transcriptional phenotypes of asthma defined by gene expression profiling of induced sputum samples', Journal of Allergy and Clinical Immunology, 127 153.e9-160.e9 (2011) [C1]
2011Baines KJ, Simpson JL, Gibson PG, 'Innate immune responses are increased in chronic obstructive pulmonary disease', PLoS ONE, 36 e18426 (2011) [C1]
2010Li J, Wang W, Baines KJ, Bowden NA, Hansbro PM, Gibson PG, et al., 'IL-27/IFN-y induce MyD88-dependent steroid-resistant airway hyperresponsiveness by inhibiting glucocorticoid signaling in macrophages', Journal of Immunology, 185 4401-4409 (2010) [C1]
2010Baines KJ, Simpson JL, Bowden NA, Scott R, Gibson PG, 'Differential gene expression and cytokine production from neutrophils in asthma phenotypes', European Respiratory Journal, 35 522-531 (2010) [C1]
2009Simpson JL, Baines KJ, Boyle MJ, Scott R, Gibson PG, 'Oncostatin M (OSM) is increased in asthma with incompletely reversible airflow obstruction', Experimental Lung Research, 35 781-794 (2009) [C1]
2009Baines KJ, Simpson JL, Scott R, Gibson PG, 'Immune responses of airway neutrophils are impaired in asthma', Experimental Lung Research, 35 554-569 (2009) [C1]
2009Baines KJ, Wood LG, Gibson PG, 'The nutrigenomics of asthma: Molecular mechanisms of airway neutrophilia following dietary antioxidant withdrawal', OMICS: A Journal of Integrative Biology, 13 355-365 (2009) [C1]
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Conference (37 outputs)

YearCitationAltmetricsLink
2014Wright T, Gibson P, Simpson J, Mcdonald V, Wood L, Baines K, 'ALARMINS IN ASTHMA AND COPD: RELATIONSHIPS TO INFLAMMATORY PHENOTYPES AND DISEASE SEVERITY', RESPIROLOGY (2014) [E3]
2014Simpson J, Gao P, Baines K, Yang I, Reynolds P, Hodge S, et al., 'GALECTIN 3 AND GALECTIN 3 BINDING PROTEIN IN ASTHMA INFLAMMATORY SUBTYPES', RESPIROLOGY (2014)
2014Baines K, Upham J, Yerkovich S, Chang A, Marchant J, Carroll M, et al., 'INTERLEUKIN-1B IS RELATED TO CLINICAL OUTCOMES IN PROTRACTED BACTERIAL BRONCHITIS', RESPIROLOGY (2014)
2013Baines KJ, Simpson JL, Mcdonald VM, Hsu AC, Gibson PG, 'DIFFERENTIAL AIRWAY GENE EXPRESSION IN COPD', RESPIROLOGY (2013) [E3]
2013Gunawardhana LP, Baines KJ, Mattes J, Murphy VE, Simpson JL, Gibson PG, 'EPIGENETIC ALTERATIONS IN INFANTS ASSOCIATED WITH MATERNAL ASTHMA DURING PREGNANCY', RESPIROLOGY (2013) [E3]
2013Simpson JL, Baines KJ, Ryan NM, Gibson PG, 'NEUTROPHILIC ASTHMA IS CHARACTERIZED BY INCREASED GERD AND RHINOSINUSITIS WITH SLEEP DISTURBANCE', RESPIROLOGY (2013) [E3]
2013Wang G, Baines KJ, Fu JJ, Gibson PG, 'MAST CELL-BASED PHENOTYPES OF ASTHMA IN INDUCED SPUTUM SAMPLES', RESPIROLOGY (2013) [E3]
2012Baines KJ, Simpson JL, Wood LG, Scott RJ, Gibson PG, 'Sputum gene expression of mast cell specific proteases are increased in eosinophilic asthma', Respirology, Canberra, ACT (2012) [E3]
2012Baines KJ, Simpson JL, Wood LG, Scott RJ, Gibson PG, 'Induced sputum differential gene expression implicates increased p38 signalling activity in severe asthma', Respirology, Canberra, ACT (2012) [E3]
2012Simpson JL, Phipps S, Baines KJ, Oreo K, Gibson PG, 'NALP3 inflammasome activation in neutrophilic asthma', Respirology, Canberra, ACT (2012) [E3]
2011Baines KJ, Simpson JL, Scott R, Wood LG, Gibson PG, 'Analysis of systemic gene expression according to inflammatory phenotype of asthma', Respirology, Perth, WA (2011) [E3]
2011Baines KJ, Simpson JL, Scott R, Wood LG, Gibson PG, 'Sputum gene expression of mast cell tryptase and carboxypeptidase A3 are increased in eosinophilic asthma', European Respiratory Society Annual Congress 2011 Abstracts, Amsterdam (2011) [E3]
2011Baines KJ, Simpson JL, Scott R, Wood LG, Gibson PG, 'Systemic upregulation of neutrophil a-defensins and serine proteases in neutrophilic asthma', European Respiratory Society Annual Congress 2011 Abstracts, Amsterdam (2011) [E3]
2011Baines KJ, Tooze MK, Wark PA, 'Rhinovirus infected airway epithelial cells have an increased pro-inflammatory response in COPD', Respirology, Perth, WA (2011) [E3]

Co-authors: Peter Wark

2011Gunawardhana LP, Baines KJ, Simpson JL, Mattes J, Murphy VE, Gibson PG, 'Maternal asthma is associated with alterations in DNA methylation profile of peripheral blood of infants', Respirology, Perth, WA (2011) [E3]
2011Oliver BG, Tang FS, Van Ly D, Burgess JK, Black JL, Baines KJ, 'Imiquimod, poly I:c and rhinovirus induce interleukin (iL)-6 and IL-8 release from polymorphonuclear cells and peripheral blood mononuclear cells: Effect of dexamethasone', American Journal of Respiratory and Critical Care Medicine, Denver, CO (2011) [E3]
2011Fu J, Baines KJ, Wood LG, Scott HA, Gibson PG, 'Low-grade systemic inflammation is associated with airway neutrophilia in asthma', Respirology, Shanghai (2011) [E3]
2011Baines KJ, Simpson JL, Scott R, Wood LG, Gibson PG, 'Induced sputum differential gene expression implicates increased p38 signalling activity in severe asthma', European Respiratory Society Annual Congress 2011 Abstracts, Amsterdam (2011) [E3]
2011Fu J, Baines KJ, Gibson PG, Scott HA, Wood LG, 'Systemic inflammation mediates airway neutrophilia via the regulation of IL-8 receptor mRNA expression', Respirology, Shanghai (2011) [E3]
2011Oreo K, Baines KJ, Gibson PG, Hansbro PM, 'Pro-inflammatory cytokine production is impaired in response to TLR2 activation in healthy ageing and COPD', Respirology, Perth, WA (2011) [E3]
2011Wang F, Xy HA, Baines KJ, Gunawardhana LP, Simpson JL, Ki F, Gibson PG, 'Is chalamydophyla a pneumoniae infection related to non-eosinophilic asthma?', Respirology, Perth, WA (2011) [E3]
2010Baines KJ, Simpson JL, Scott R, Wood LG, Gibson PG, 'Molecular phenotypes of asthma defined by gene expression profiling', American Journal of Respiratory and Critical Care Medicine, New Orleans, LO (2010) [E3]
2010Baines KJ, Simpson JL, Scott R, Wood LG, Gibson PG, 'Analysis of systemic gene expression according to inflammatory phenotype of asthma', Biomarker Discovery Conference, Shoal Bay, NSW (2010) [E3]
2010Baines KJ, Simpson JL, Scott RJ, Wood LG, Gibson PG, 'Molecular profiling of asthma defined by gene expression', Respirology, Brisbane, QLD (2010) [E3]
2010Baines KJ, Simpson JL, Scott R, Wood LG, Gibson PG, 'Molecular phenotypes of asthma defined by gene expression profiling', Respirology, Brisbane, QLD (2010) [E3]
2009Baines KJ, Wood LG, Gibson PG, 'Molecular mechanisms of airway neutrophilia following a low antioxidant diet', Respirology, Darwin, NT (2009) [E3]
2009Baines KJ, Simpson JL, Scott R, Wood LG, Gibson PG, 'Genome wide gene expression of induced sputum in non-eosinophilic asthma', AMATA 2009, Katoomba, NSW (2009) [E3]
2009Oreo K, Baines KJ, Gibson PG, Hansbro PM, Simpson JL, 'Toll-like receptor agonists stimulate cytokine release from blood but not airway cells', Respirology, Darwin, NT (2009) [E3]
2009Bowden NA, Ashton KA, Stibbard GJ, Cox MB, Baines KJ, Scott R, 'Predicting xeroderma pigmentosum complementation group by gene expression profiling', AMATA 2009, Katoomba, NSW (2009) [E3]
2009Baines KJ, Grissell TV, Gibson PG, Wark PA, 'Molecular mechanisms of rhinovirus infection of primary bronchial epithelial cells', Respirology, Darwin, NT (2009) [E3]
2008Bowden NA, Baines KJ, Cox MB, Scott R, 'Altered gene expression in nucleotide excision repair deficient fibroblasts after UV-light exposure', AACR Meeting Abstracts, San Diego, CA (2008) [E3]

Co-authors: Rodney Scott

2008Bowden NA, Baines KJ, Cox MB, Scott R, 'Response to uv-light exposure in fibroblasts with differential nucleotide excision repair capacity', ASMR XVII NSW Scientific Meeting: Programme and Abstracts, Sydney, NSW (2008) [E3]

Co-authors: Rodney Scott

2008Bowden NA, Ashton KA, Baines KJ, Cox MB, Scott R, 'Altered gene expression after UV-light induced DNA damage', Conference on Translational Cancer Research: Abstracts, Newcastle, NSW (2008) [E3]
2008Baines KJ, Simpson JL, Scott R, Gibson PG, 'Ageing alters airway and circulating neutrophil function', Respirology, Melbourne, VIC (2008) [E3]
2008Baines KJ, Simpson JL, Scott R, Gibson PG, 'Innate immune responses of airway neutrophils are impaired in neutrophilic asthma', Respirology, Melbourne, VIC (2008) [E3]
2007Baines KJ, Bowden NA, Scott R, Simpson JL, Gibson PG, 'Molecular analysis of neutrophils in asthma subtypes', Respirology (TSANZ Abstracts-Posters), Auckland (2007) [E3]
2006Baines KJ, Simpson JL, Scott R, Bell NV, Boyle MJ, Gibson PG, 'Enhanced IL-8 release from neutrophils in non-eosinophilic asthma', Respirology, Canberra (2006) [E3]
Show 34 more
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Grants and Funding

Summary

Number of grants28
Total funding$1,796,409

- Indicates that the researcher may be seeking students for this project.

Click on a grant title below to expand the full details for that specific grant.

2014 (4 grants)

Greenland Study$140,000
Funding Body: Bispebjerg Hospital

Project Team
Conjoint Professor Peter Gibson, Doctor Katie Baines, Professor Vibeke Backer
SchemeRole
International CollaborationInvestigator
Total AmountFunding StartFunding Finish
$140,00020142016
GNo:G1400539

Identifying biomarkers that predict severe asthma exacerbations during pregnancy$60,000
Funding Body: Thoracic Society of Australia and New Zealand

Project Team
Doctor Katie Baines
SchemeRole
TSANZ/National Asthma Council Australia - Asthma and Airways Career Development FellowshipChief Investigator
Total AmountFunding StartFunding Finish
$60,00020142014
GNo:G1400730

Identifying biomarkers that predict severe asthma exacerbations during pregnancy$27,512
Funding Body: John Hunter Hospital Charitable Trust Fund

Project Team
Doctor Katie Baines, Emeritus Professor Michael Hensley
SchemeRole
Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$27,51220142014
GNo:G1400631

Thoracic Society of Australia and New Zealand, Adelaide Australia, 4-9 April 2014$1,885
Funding Body: University of Newcastle - Faculty of Health and Medicine

Project Team
Doctor Katie Baines
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$1,88520142014
GNo:G1400186

2013 (5 grants)

Gene Expression Biomarkers Predict Severe Asthma Inflammatory Phenotype, Activation Mechanisms and Treatment Response$449,307
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Doctor Katie Baines, Conjoint Professor Peter Gibson, Associate Professor Jodie Simpson
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$449,30720132015
GNo:G1200188

Protracted bacterial bronchitis: long term outcomes, systemic and airway predictors of recurrence$76,526
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Anne Chang, Professor John Upham, Conjoint Professor Peter Gibson, Dr Stephanie Yerkovich, Doctor Katie Baines, Dr Sandra Hodge, Mrs Susan Pizzuto, Associate Professor Ian Masters, Dr Helen Buntain
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$76,52620132016
GNo:G1200534

BD FACSCanto II Violet Laser (405nm) upgrade including Trigon and 2 photomultiplier tubes (PMTs)$25,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor Peter Wark, Doctor Alan Hsu, Doctor Katie Baines, Associate Professor Jodie Simpson, Conjoint Professor Peter Gibson, Ms Hayley See
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$25,00020132013
GNo:G1201180

DP73 Digital colour and monochrome camera + cellSens software + Xcite120 fluorescence lamp illuminator$20,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Paul Foster, Doctor Alan Hsu, Professor Phil Hansbro, Professor Joerg Mattes, Doctor Katie Baines, Associate Professor Jodie Simpson, Professor Rakesh Kumar, Doctor Nicole Hansbro, Doctor Steven Maltby, Doctor Ming Yang, Doctor Gerard Kaiko, Doctor Jay Horvat, Doctor Simon Keely, Doctor Andrew Jarnicki, Doctor Michael Fricker
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$20,00020132013
GNo:G1201186

Thoracic Society of Australia and New Zealand$1,675
Funding Body: University of Newcastle - Faculty of Health and Medicine

Project Team
Doctor Katie Baines
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$1,67520132013
GNo:G1300405

2012 (5 grants)

2011 Research Fellowship - PRCARD$333,302
Funding Body: University of Newcastle

Project Team
Doctor Katie Baines
SchemeRole
Research FellowshipChief Investigator
Total AmountFunding StartFunding Finish
$333,30220122014
GNo:G1200356

Phenotype based management of severe persistent asthma$34,454
Funding Body: John Hunter Hospital Charitable Trust Fund

Project Team
Associate Professor Vanessa McDonald, Doctor Katie Baines, Conjoint Professor Peter Gibson
SchemeRole
Research GrantInvestigator
Total AmountFunding StartFunding Finish
$34,45420122012
GNo:G1200211

Body plethysmograph respiratory function system$33,076
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor Peter Gibson, Conjoint Professor Peter Wark, Associate Professor Lisa Wood, Associate Professor Jodie Simpson, Doctor Katie Baines, Doctor Vanessa Murphy, Doctor Jeffrey Pretto, Emeritus Professor Michael Hensley, Ms Jenny Mackney
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$33,07620122012
GNo:G1100973

Phenotype based management of severe persistent asthma$20,000
Funding Body: Hunter Medical Research Institute

Project Team
Associate Professor Vanessa McDonald, Doctor Katie Baines, Conjoint Professor Peter Gibson
SchemeRole
Research GrantInvestigator
Total AmountFunding StartFunding Finish
$20,00020122012
GNo:G1101169

Gene expression markers, mechanisms and steroid response of neutrophilic asthma$15,000
Funding Body: University of Newcastle

Project Team
Doctor Katie Baines
SchemeRole
Fellowship GrantChief Investigator
Total AmountFunding StartFunding Finish
$15,00020122012
GNo:G1200082

2011 (7 grants)

Transcriptional Phenotyping of COPD and the relationship between neutrophilic airway inflammation, airway infection and activation of proinflammatory pathways$24,000
Funding Body: John Hunter Hospital Charitable Trust Fund

Project Team
Doctor Katie Baines, Conjoint Professor Peter Gibson, Associate Professor Jodie Simpson
SchemeRole
Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$24,00020112011
GNo:G1100635

Identification of a specific biomarker signature that identifies asthma phenotype $23,700
Funding Body: Hunter Medical Research Institute

Project Team
Doctor Katie Baines, Associate Professor Jodie Simpson, Conjoint Professor Peter Gibson
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$23,70020112011
GNo:G1001054

Transcriptional Phenotyping of COPD and the relationship between neutrophilic airway inflammation, airway infection and activation of proinflammatory pathways$20,000
Funding Body: Australian Lung Foundation

Project Team
Doctor Katie Baines
SchemeRole
Grant-In-Aid for New and Emerging ResearchersChief Investigator
Total AmountFunding StartFunding Finish
$20,00020112011
GNo:G1000976

Epigenetic changes in infants associated with maternal asthma during pregnancy$10,000
Funding Body: Thoracic Society of Australia and New Zealand

Project Team
Doctor Katie Baines
SchemeRole
Grant-in-aid (supported by Merck Sharp & Dohme)Chief Investigator
Total AmountFunding StartFunding Finish
$10,00020112011
GNo:G1000991

Lung Function (Spirometry) testing and sputum induction equipment - establishing 3 new clinical workstations. Medgraphics CPFS/d USB spirometer with breezesuite software (x3). Laptop computer (x3). Ul$10,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor Peter Gibson, Associate Professor Jodie Simpson, Associate Professor Lisa Wood, Doctor Katie Baines, Conjoint Professor Peter Wark, Doctor Vanessa Murphy
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$10,00020112011
GNo:G1100038

PULSE Education Prize$4,000
Funding Body: Hunter Medical Research Institute

Project Team
Doctor Katie Baines
SchemeRole
PULSE Education PrizeChief Investigator
Total AmountFunding StartFunding Finish
$4,00020112011
GNo:G1100342

Thoracic Society of Australia and New Zealand, Perth Convention and Exhibition Centre, 2 - 6 April 2011$1,289
Funding Body: University of Newcastle - Faculty of Health and Medicine

Project Team
Doctor Katie Baines
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$1,28920112011
GNo:G1100297

2010 (1 grants)

Real time PCR machine (Mastercycler ep realplex2 from Epprndorf) $34,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Associate Professor Jodie Simpson, Conjoint Professor Peter Gibson, Conjoint Professor Peter Wark, Associate Professor Lisa Wood, Doctor Vanessa Murphy, Doctor Robert Scott, Doctor Katie Baines
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$34,00020102010
GNo:G1000056

2009 (1 grants)

Epigenetic regulation of airways inflammation in non-eosinophilic asthma$63,354
Funding Body: Asthma Foundation of New South Wales

Project Team
Conjoint Professor Peter Gibson, Doctor Katie Baines, Associate Professor Jodie Simpson
SchemeRole
PhD ScholarshipsInvestigator
Total AmountFunding StartFunding Finish
$63,35420092011
GNo:G0189748

2008 (3 grants)

Molecular mechanisms and treatment of non-eosinophilic asthma$300,000
Funding Body: Hunter Medical Research Institute

Project Team
Associate Professor Jodie Simpson, Doctor Katie Baines
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$300,00020082010
GNo:G0188825

Molecular subtypes of asthma defined by gene expression profiling$9,955
Funding Body: University of Newcastle

Project Team
Doctor Katie Baines
SchemeRole
Early Career Researcher GrantChief Investigator
Total AmountFunding StartFunding Finish
$9,95520082008
GNo:G0189618

American Thoracic Society, Metro Toronto Convention Centre, 16/5/2008 - 21/5/2008$1,700
Funding Body: University of Newcastle

Project Team
Doctor Katie Baines
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$1,70020082008
GNo:G0188599

2006 (1 grants)

Molecular Pathogenesis of Non-Eosinophilic Asthma$18,837
Funding Body: Asthma Foundation of New South Wales

Project Team
Doctor Katie Baines, Conjoint Professor Peter Gibson
SchemeRole
PhD ScholarshipsChief Investigator
Total AmountFunding StartFunding Finish
$18,83720062006
GNo:G0185985

2004 (1 grants)

Molecular Pathogensis of Non-Eosinphilic Asthma$37,837
Funding Body: Asthma Foundation of New South Wales

Project Team
Conjoint Professor Peter Gibson, Professor Rodney Scott, Doctor Katie Baines
SchemeRole
PhD ScholarshipsInvestigator
Total AmountFunding StartFunding Finish
$37,83720042005
GNo:G0183715
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Research Supervision

Number of current supervisions4
Total current UoN Masters EFTSL0.4
Total current UoN PhD EFTSL0.8

For supervisions undertaken at an institution other that the University of Newcastle, the institution name is listed below the program name.

Current Supervision

CommencedProposed
Completion
ProgramSupervisor TypeResearch Title
20142016M Philosophy (Medicine)Co-SupervisorThe Effects of Galectin-3 on Alveolar Macrophage Function in Asthma
20132017PhD (Medicine)Co-SupervisorThe Role of Comorbidities and Inflammation in COPD
20122016PhD (Medical Biochemistry)Co-SupervisorFatty Acids and the Innate Immune Response
20092013PhD (Medicine)Co-SupervisorEpigenetic Regulation of Airway Inflammation in Asthma
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Dr Katherine (Katie) Baines

Work Phone(02) 40420090
Fax(02) 40420046
Email
PositionUoN Postdoctoral Fellow
Respiratory Medicine
School of Medicine and Public Health
Faculty of Health and Medicine
The University of Newcastle, Australia
Office
Room 2109 Level 2 West Wing ,
Hunter Medical Research Institute,
HMRI Building
URL:www.newcastle.edu.au/profile/katherine-baines