Staff Profile

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Career Summary

Biography

Background - PhD in Pharmacology and Diploma in Pharmacy.

Qualifications

  • PhD, Monash University, 14/03/2000
  • Bachelor of Science (Honours), University of Witwatersrand, 28/04/1987
  • Diploma in Pharmacy, Technikon Witwatersrand - South Africa, 20/12/1979
  • Bachelor of Science, Rhodes University, 10/04/1976

Research

Research keywords

  • Pharmaceutical Sciences
  • Pharmacology

Research expertise

A range of methods including organ bath studies, live cell imaging, immunohistochemistry and electrophysiology are used to elucidate the various cell signaling pathways that contribute to the contractility of the mouse myometrium in response to various autacoids, neurotransmitters and hormones. We have several projects that study possible factors affecting premature birth which remains a major unsolved problem that affects some 15% of births internationally and is increasing in incidence.

Fields of Research

CodeDescriptionPercentage
111500Pharmacology And Pharmaceutical Sciences60
110399Clinical Sciences Not Elsewhere Classified20
111699Medical Physiology Not Elsewhere Classified20

Invitations

Dr Karen Kerr
Bond University, Gold Coast, QLD,, Australia (Invited Presenter)
2010

Collaboration

Pharmacology of the pelvic organs (uterus, bladder and prostate) with a focus on cell signaling mechanisms understanding mechanisms that may affect uterine motility urinary incontinence and benign prostatic hyperplasia. Techniques used include functional studies (organ bath work) and immunohistochemistry.

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Publications

For publications that are currently unpublished or in-press, details are shown in italics.

Click on a category title below to expand the list of citations for that specific category.

Chapter (1 outputs)

YearCitationAltmetricsLink
2007Candenas ML, Pennefather JN, Kerr KP, Perez-Hernandez N, Pinto FM, 'Tachykinins and smooth muscle function', New Frontiers in Smooth Muscle Biology and Physiology, Transworld Research Network, Kerala, India 383-411 (2007) [B1]

Journal article (8 outputs)

YearCitationAltmetricsLink
2014Kerr KP, Mate KE, Magin PJ, Marley J, Stocks NP, Disler P, Pond CD, 'The prevalence of co-prescription of clinically relevant CYP enzyme inhibitor and substrate drugs in community-dwelling elderly Australians', JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 39 383-389 (2014) [C1]
2013Lam M, Kerr KP, Exintaris B, 'Involvement of Rho-Kinase Signaling Pathways in Nerve Evoked and Spontaneous Contractions of the Guinea Pig Prostate', JOURNAL OF UROLOGY, 189 1147-1154 (2013) [C1]
2011Gravina FS, Jobling P, Kerr KP, De Oliveira R, Parkington HC, Van Helden DF, 'Oxytocin depolarizes mitochondria in isolated myometrial cells', Experimental Physiology, 96 949-956 (2011) [C1]
2011Lam M, Kerr KP, Ventura S, Exintaris B, 'Extracellular Ca2+ entry and mobilization of inositol trisphosphate-dependent Ca2+ stores modulate histamine and electrical field stimulation induced contractions of the guinea-pig prostate', Pharmacological Research, 64 235-241 (2011) [C1]
2010Gravina FS, Parkington HC, Kerr KP, De Oliveira R, Jobling P, Coleman HA, et al., 'Role of mitochondria in contraction and pacemaking in the mouse uterus', British Journal of Pharmacology, 161 1375-1390 (2010) [C1]
2008Patak E, Pennefather JN, Gozali M, Candenas L, Kerr K, Exintaris B, et al., 'Functional characterisation of hemokinin-1 in mouse uterus', European Journal of Pharmacology, 601 148-153 (2008) [C1]
2007Chetty N, Coupar IM, Chess-Williams R, Kerr KP, 'Demonstration of 5-HT3 receptor function and expression in the mouse bladder', Naunyn-Schmiedebergs Archives of Pharmacology, 375 359-368 (2007) [C1]
2006Kerr KP, 'The effect of histamine on field-stimulated contractions of the guinea-pig prostate', Naunyn-Schmiedebergs Archives of Pharmacology, 373 237-244 (2006) [C1]
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Conference (14 outputs)

YearCitationAltmetricsLink
2013Kerr KP, Mate KE, Williams E, Pond D, Magin PJ, 'Anticholinergic load in community dwelling elderly Australians with dementia', ASCEPT Annual Scientific Meeting, Melbourne, Vic (2013) [E3]
2012Mate KE, Kerr KP, Pond CD, Magin PJ, 'Potentially inappropriate medications in the elderly - A case study', Symposium Program. Interprofessional Education for Quality Use of Medicines, Newcastle Beach, NSW (2012) [E3]
2012Kerr KP, Mate KE, Pond CD, Magin PJ, Stocks N, Marley JE, Disler P, 'Prescribing in the elderly - cytochrome P450 (CYP) enzyme inhibitors and substrates', ASCEPT-APSA 2012 Oral Abstracts, Sydney, NSW (2012) [E3]
2012Kerr KP, Mate KE, Pond CD, Magin PJ, 'An ACE inhibitor and a Sartan - Is there a place for this combination? A real-life case study for students in the health professions', Symposium Program. Interprofessional Education for Quality Use of Medicines, Newcastle Beach, NSW (2012) [E3]
2010Gravina FS, Van Helden DF, De Oliveira R, Kerr KP, Jobling P, 'Relaxant effects of methanandamide unmasked by indomethacin in the mouse uterus', Australasian Society of Clinical and Experimental Pharmacology and Toxicology (ASCEPT) Annual Scientific Meeting, Melbourne, 2010, Melbourne, Vic (2010) [E3]
2009Gravina FS, Jobling P, Kerr KP, De Oliveira R, Van Helden DF, 'Identification of cannabinoid receptor 1 and the effect of methanandamide on uterine contractions of the mouse uterus', 1st National Symposium on Advances in Urogenital and Gut Research, Melbourne, VIC (2009) [E3]
2009Gravina FS, Kerr KP, Sandow S, De Oliveira R, Parkington H, Imtiaz MS, Van Helden DF, 'Intracellular calcium stores in mouse uterus: SR and Mitochondria', Journal of Physiological Sciences, Kyoto, Japan (2009) [E3]

Co-authors: Dirk vanHelden

2009Kerr KP, Jobling P, Gravina FS, Van Helden DF, 'Contractility of the lower uterus and upper vagina in the mouse', 43rd ASCEPT Annual Scientific Meeting: Proceedings, Sydney, NSW (2009) [E3]
2009Hollins SL, Johnstone DM, Graham R, Van Helden DF, Kerr KP, Laver DR, et al., 'Cardiac gene expression in mouse models of iron loading disorders', 2009 International Biolron Society Meeting: Program Book, Porto, Portugal (2009) [E3]
2009Hollins SL, Johnstone DM, Van Helden DF, Kerr KP, Laver DR, Metelerkamp KM, et al., 'Cardiac gene expression in mouse models of iron loading', ASMR XVII NSW Scientific Meeting: Programme and Abstracts, Sydney, NSW (2009) [E3]
2009Lam MH-S, Kerr KP, Exintaris B, 'Investigation of internal Ca2+ release in spontaneous electrical activity and histamine-induced contractions in the guinea-pig prostate', Proceedings of the XXXVI International Congress of Physiological Sciences (IUPS2009) Function of Life: Elements and Integration, Kyoto, Japan (2009) [E3]
2008Gravina FS, Kerr KP, De Oliveira R, Parkington H, Imtiaz MS, Van Helden DF, 'Effects of the mitochondrial inhibitors CCCP, rotenone and CGP37157 on spontaneous contractions in the mouse uterus', Proceedings of the Australian Health and Medical Research Congress 2008, Brisbane, QLD (2008) [E3]

Co-authors: Dirk vanHelden

2008Lam MH, Kerr KP, Exintaris B, 'Investigation of internal Ca2+ store release through histamine and phenylephrine-induced contractions in the guinea-pig prostate', Proceedings of the Australian Health and Medical Research Congress 2008, Brisbane, QLD (2008) [E3]
2008Gravina FS, Kerr KP, Sandow S, De Oliveira R, Parkington HC, Imtiaz MS, Van Helden DF, 'Uterine spontaneous contractions in the estrous cycle and the effect of mitochondrial inhibitors', Proceedings of the Australian Physiological Society, Melbourne, VIC (2008) [E3]

Co-authors: Dirk vanHelden

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Grants and Funding

Summary

Number of grants2
Total funding$1,839

- Indicates that the researcher may be seeking students for this project.

Click on a grant title below to expand the full details for that specific grant.

2013 (1 grants)

ASCEPT Annual Scientific Meeting (Australasian Society of Clinical and Experimental Pharmacologist and Toxicologists), Melbourne Australia, 1-4 December 2013$999
Funding Body: University of Newcastle - Faculty of Health and Medicine

Project Team
Doctor Karen Kerr
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$99920132013
GNo:G1301095

2012 (1 grants)

Joint ASCEPT - APSA Conference - Medication and Safety, Sydney Convention and Exhibition Centre, 2 - 5 December 2012$840
Funding Body: University of Newcastle - Faculty of Health and Medicine

Project Team
Doctor Karen Kerr
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$84020122012
GNo:G1201070
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Research Supervision

Number of current supervisions1
Total current UoN Masters EFTSL0.1

For supervisions undertaken at an institution other that the University of Newcastle, the institution name is listed below the program name.

Current Supervision

CommencedProposed
Completion
ProgramSupervisor TypeResearch Title
20142016M Philosophy (Medical Genetic)Co-SupervisorThe Effects of Iron Dysregulation on the Heart, Lungs and Reproductive System

Past Supervision

YearProgramSupervisor TypeResearch Title
2011PhD (Human Physiology)Co-SupervisorContractile Properties of the Female Reproductive Tract
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Dr Karen Kerr

Work Phone(02) 4921 6572
Cell / Mobile Phone0423788656
Fax(02) 4921 7903
Email
PositionSenior Lecturer
School of Biomedical Sciences and Pharmacy
Faculty of Health and Medicine
The University of Newcastle, Australia
Focus AreaPharmacy and Experimental Pharmacology
Office
MS125,
Medical Sciences ,
Callaghan
University Drive
Callaghan NSW 2308
Australia
URL:www.newcastle.edu.au/profile/karen-kerr