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Professor John Attia

Academic Director

School of Medicine and Public Health

Career Summary

Biography

Professor John Attia obtained a BSc in Physiology (Faculty scholar at McGill University) and then won a 5 year MRC scholarship to complete his MD/PhD in Molecular Genetics (University of Toronto). He trained at McMaster University (Canada) in general internal medicine and obtained his fellowship with the Royal College of Physicians of Canada and the Royal Australasian College of Physicians. During this time he was awarded the Outstanding Housestaff award, the J.T. Walsh award for outstanding Internal Medicine resident, and Best Teacher in Internal Medicine. During his residency, he also completed his MSc in Epidemiology (McMaster University). He has been listed on the NHMRC register of Evidence-Based Medicine experts and has provided epidemiological expertise to the Therapeutic Goods Administration. In 2012, he won the senior research excellence award from both the Faculty of Health (University of Newcastle) and the Hunter Medical Research Institute. 

Between 1999 and 2013, he has collaborated in obtaining $13.6 million in grant income and published over 250 manuscripts (with another 5 submitted); these have garnered over 3000 citations, leading to an h-index of 30 (Scopus data April 2013). He has also submitted 7 government reports, and 7 book chapters. He has been supervisor or co-supervisor to 20 PhD students (10 graduated and 10 current) and 6 Master’s students (5 graduated, 1 current). He is currently academic director of general medicine at John Hunter Hospital responsible for the foundation and running of the advanced training program for general physicians, one of the only fully supported such programs in the state. He is also co-director of the Clinical Research Design, IT, and Statistical Support (CReDITSS) Unit, a unit that provides methodological and analysis advice to clinical researchers.

Research Expertise
John's research expertise includes clinical, molecular, and genetic epidemiology methods. Clinical epidemiology covers such topics as population- and hospital-based observational studies (cohort, case-control, crossover) and controlled clinical trials as well as studies of diagnostic tests, meta-analyses, and health services research. Molecular epidemiology focuses mainly on evaluation of biomarkers. Genetic epidemiology covers design and analysis of genome-wide association studies of various complex diseases, particularly macular degeneration and stroke. 


Qualifications

  • PhD, University of Toronto
  • Bachelor of Science, McGill University - Canada
  • Master of Science, McMaster University - Canada
  • Doctor of Medicine, University of Toronto

Keywords

  • clinical epidemiology
  • genetic epidemiology
  • public health

Languages

  • French (Fluent)

Fields of Research

CodeDescriptionPercentage
010499Statistics not elsewhere classified15
110399Clinical Sciences not elsewhere classified45
111799Public Health and Health Services not elsewhere classified40

Professional Experience

UON Appointment

DatesTitleOrganisation / Department
1/01/2014 - ProfessorUniversity of Newcastle
School of Medicine and Public Health
Australia
16/01/2012 - 16/01/2012Thesis ExaminerUniversity of Newcastle
Office of Graduate Studies
Australia

Academic appointment

DatesTitleOrganisation / Department
1/01/2006 - Epidemiology Expert to the Complementary Medicines Advisory CommitteeTherapeutic goods administration
Australia
1/01/2003 - Evidence-based medicine expert to assist groups in developing EBM guidelinesNHMRC (National Health & Medical Research Council)

Membership

DatesTitleOrganisation / Department
Member - Royal Australasian College of PhysiciansThe Royal Australasian College of Physicians
Australia

Awards

Research Award

YearAward
2005Dudley Homer Vose award
National Heart Foundation of Australia
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Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Book (5 outputs)

YearCitationAltmetricsLink
2004D'Este CA, Byles JE, Attia JR, Brown AM, Second Mortality and Cancer Incidence Report, -, Newcastle, Australia (2004) [A2]
Co-authorsCatherine Deste, Julie Byles
2004D'Este CA, Byles JE, Attia JR, Brown AM, Report on the General Health and Medical Study, -, Newcastle, Australia, 463 (2004) [A2]
Co-authorsCatherine Deste, Julie Byles
2003D'Este CA, Byles JE, Attia JR, Brown AM, Literature Review Report, -, Newcastle, Australia (2003) [A2]
Co-authorsCatherine Deste, Julie Byles
2003D'Este CA, Byles JE, Attia JR, Brown AM, Report on the qualitative interviews, -, Newcastle, Australia (2003) [A2]
Co-authorsJulie Byles, Catherine Deste
2003D'Este CA, Byles JE, Attia JR, Brown AM, Interim mortality and cancer incidence report, -, Newcastle, Australia (2003) [A2]
Co-authorsCatherine Deste, Julie Byles
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Chapter (4 outputs)

YearCitationAltmetricsLink
2015Riveros C, Vimieiro R, Holliday EG, Oldmeadow C, Wang JJ, Mitchell P, et al., 'Identification of genome-wide snp¿snp and snp¿clinical boolean interactions in age-related macular degeneration', , Humana Press Inc. (2015)

We propose here a methodology to uncover modularities in the network of SNP¿SNP interactions most associated with disease. We start by computing all possible Boolean binary SNP interactions across the whole genome. By constructing a weighted graph of the most relevant interactions and via a combinatorial optimization approach, we fnd the most highly interconnected SNPs. We show that the method can be easily extended to fnd SNP/environment interactions. Using a modestly sized GWAS dataset of age-related macular degeneration (AMD), we identify a group of only 19 SNPs, which include those in previously reported regions associated to AMD. We also uncover a larger set of loci pointing to a matrix of key processes and functions that are affected. The proposed integrative methodology extends and overlaps traditional statistical analysis in a natural way. Combinatorial optimization techniques allow us to fnd the kernel of the most central interactions, complementing current methods of GWAS analysis and also enhancing the search for gene¿environment interaction.

DOI10.1007/978-1-4939-2155-3_12
Co-authorsLiz Holliday, Christopher Oldmeadow, Pablo Moscato, Rodney Scott
2013Holliday EG, Oldmeadow CJ, Maguire JM, Attia JR, 'Candidate gene association studies in stroke', Stroke Genetics, Springer Verlag, London 9-23 (2013) [B1]
Co-authorsLiz Holliday, Christopher Oldmeadow, Jane Maguire
2011Attia JR, 'Moving beyond sensitivity and specificity: Using likelihood ratios to help interpret diagnostic tests', Abnormal Laboratory Results, McGraw Hill, North Ryde, NSW 23-29 (2011) [B2]
2002Jaeschke R, Guyatt G, Barratt A, Walter S, McAlister F, Attia JR, 'Part 2: Beyond the basics. Therapy and understanding the results. Measures of association', Users' guides to the medical literature : a manual for evidence-based clinical practice, AMA Press, Chicago, Ill. 706 (2002) [B2]
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Journal article (376 outputs)

YearCitationAltmetricsLink
2015Kypri K, Wilson A, Attia J, Sheeran PJ, McCambridge J, 'Effects of study design and allocation on self-reported alcohol consumption: randomized trial.', Trials, 16 127 (2015)
DOI10.1186/s13063-015-0642-0Author URL
Co-authorsAmanda Wilson, Kypros Kypri
2015Vashum KP, McEvoy MA, Hancock SJ, Islam MR, Peel R, Attia JR, Milton AH, 'Prevalence of and associations with excessive daytime sleepiness in an Australian older population.', Asia Pac J Public Health, 27 NP2275-NP2284 (2015)
DOI10.1177/1010539513497783Author URL
Co-authorsRoseanne Peel, Milton Hasnat
2015Bidarian-Moniri A, Nilsson M, Rasmusson L, Attia J, Ejnell H, 'The effect of the prone sleeping position on obstructive sleep apnoea', ACTA OTO-LARYNGOLOGICA, 135 79-84 (2015)
DOI10.3109/00016489.2014.962183Author URL
2015Hiles SA, Baker AL, de Malmanche T, McEvoy M, Boyle M, Attia J, 'Unhealthy lifestyle may increase later depression via inflammation in older women but not men', Journal of Psychiatric Research, 63 65-74 (2015)

Depression and inflammatory markers have a reliable cross-sectional association although less is known about the prospective relationship. The current study investigated whether pro-inflammatory markers are prospectively associated with depression, and whether indicators of unhealthy lifestyle, physical health and psychosocial functioning may drive this association. Participants were drawn from the Hunter Community Study, a community-dwelling cohort of individuals aged 55-85 years (N=1410). Participants completed baseline physiological assessment, health-related questionnaires, and blood sampling for the analysis of inflammatory markers, C-reactive protein (CRP) and interleukin (IL)-6. Participants completed the same depressive symptom questionnaire again after 3.5-5.5 years. Depression outcomes at follow-up were analysed dichotomously using established scale cut-off scores and continuously as a "residual score", representing the variation in follow-up depressive symptoms not explained by baseline symptoms and age. Analyses were conducted on males and females separately. At baseline, indicators of unhealthy lifestyle, physical health and psychosocial functioning were associated with depressive symptoms and inflammatory markers. For males, there were no relationships between inflammatory markers and follow-up depression outcomes. In females, IL-6 was significantly associated with depression outcomes in univariate, but not multivariate analyses. However, IL-6 significantly mediated the association between the predictors of waist-to-hip ratio, smoking and psychological coping at baseline, and follow-up depression outcomes. The results support the inflammatory hypothesis of depression, although females may be more vulnerable to effects. The findings raise the possibility that unhealthy lifestyle and psychosocial stress may drive inflammation and subsequent depressive symptoms.

DOI10.1016/j.jpsychires.2015.02.010
Co-authorsAmanda Baker
2015Rannikmäe K, Davies G, Thomson PA, Bevan S, Devan WJ, Falcone GJ, et al., 'Common variation in COL4A1/COL4A2 is associated with sporadic cerebral small vessel disease', Neurology, 84 918-926 (2015)

Objectives: We hypothesized that common variants in the collagen genes COL4A1/COL4A2 are associated with sporadic forms of cerebral small vessel disease. Methods: We conducted meta-analyses of existing genotype data among individuals of European ancestry to determine associations of 1,070 common single nucleotide polymorphisms (SNPs) in the COL4A1/COL4A2 genomic region with the following: intracerebral hemorrhage and its subtypes (deep, lobar) (1,545 cases, 1,485 controls); ischemic stroke and its subtypes (cardioembolic, large vessel disease, lacunar) (12,389 cases, 62,004 controls); and white matter hyperintensities (2,733 individuals with ischemic stroke and 9,361 from population-based cohorts with brain MRI data). We calculated a statistical significance threshold that accounted for multiple testing and linkage disequilibrium between SNPs (p < 0.000084). Results: Three intronic SNPs in COL4A2 were significantly associated with deep intracerebral hemorrhage (lead SNP odds ratio [OR] 1.29, 95% confidence interval [CI] 1.14-1.46, p = 0.00003; r2 > 0.9 between SNPs). Although SNPs associated with deep intracerebral hemorrhage did not reach our significance threshold for association with lacunar ischemic stroke (lead SNP OR 1.10, 95% CI 1.03-1.18, p = 0.0073), and with white matter hyperintensity volume in symptomatic ischemic stroke patients (lead SNP OR 1.07, 95% CI 1.01-1.13, p = 0.016), the direction of association was the same. There was no convincing evidence of association with white matter hyperintensities in population-based studies or with non-small vessel disease cerebrovascular phenotypes. Conclusions: Our results indicate an association between common variation in the COL4A2 gene and symptomatic small vessel disease, particularly deep intracerebral hemorrhage. These findings merit replication studies, including in ethnic groups of non-European ancestry.

DOI10.1212/WNL.0000000000001309
Co-authorsLiz Holliday, Chris Levi
2015Greenop KR, Miller M, Bailey HD, Scott RJ, Attia J, Bower C, et al., 'Paternal dietary folate, B6 and B12 intake, and the risk of childhood brain tumors', Nutrition and Cancer, 67 224-230 (2015)

It is biologically plausible that a paternal preconception diet low in nutrients related to DNA integrity could affect sperm DNA and subsequently risk of cancer in the offspring. The aim of this analysis was to investigate whether paternal preconception dietary folate, B6, or B12 intake was associated with the risk of childhood brain tumors (CBT) in an Australian case-control study. Cases <15 years of age were recruited from 10 Australian pediatric oncology centers between 2005 and 2010, and controls from random-digit dialing, frequency-matched to cases on age, sex, and state of residence. Paternal dietary information was obtained by food-frequency questionnaires. Nutrient values were energy adjusted and divided into tertiles for analysis by unconditional logistic regression. In fathers with relevant data (237 cases and 629 controls), no association with dietary folate and B6 and risk of CBT was seen; high B12 intake was associated with an increased risk of CBT (odds ratio highest vs. lowest tertile: 1.74, 95% confidence interval: 1.14, 2.66) without an increasing trend. These results do not support the hypothesis that paternal dietary folate intake influences the risk of CBT. The increased OR observed between dietary B12 intake and risk of CBT is without any certain explanation.

DOI10.1080/01635581.2015.990571
Co-authorsRodney Scott
2015Greenop KR, Bailey HD, Miller M, Scott RJ, Attia J, Ashton LJ, et al., 'Breastfeeding and nutrition to 2 years of age and risk of childhood acute lymphoblastic leukemia and brain tumors', Nutrition and Cancer, 67 431-441 (2015)

Acute lymphoblastic leukemia (ALL) and childhood brain tumors (CBT) are 2 of the most common forms of childhood cancer, but little is known of their etiology. In 2 nationwide case-control studies we investigated whether breastfeeding, age of food introduction, or early diet are associated with the risk of these cancers. Cases aged 0-14 years were identified from Australian pediatric oncology units between 2003 and 2007 (ALL) and 2005 and 2010 (CBT) and population-based controls through nationwide random-digit dialing. Mothers completed questionnaires giving details of infant feeding up to the age of 2 yr. Data from 322 ALL cases, 679 ALL controls, 299 CBT cases, and 733 CBT controls were analysed using unconditional logistic regression. Breastfeeding was associated with a reduced risk of ALL [odds ratio (OR) = 0.52, 95% confidence interval (CI): 0.32, 0.84), regardless of duration. Introduction of artificial formula within 14 days of birth was positively associated with ALL (OR = 1.57, 95% CI: 1.03, 2.37), as was exclusive formula feeding to 6 mo (OR = 1.81, 95% CI: 1.07, 3.05). No associations were seen between breastfeeding or formula use and risk of CBT. Our results suggest that breastfeeding and delayed introduction of artificial formula may reduce the risk of ALL but not CBT.

DOI10.1080/01635581.2015.998839
CitationsScopus - 1Web of Science - 1
Co-authorsRodney Scott
2015Sapkota Y, Low S-K, Attia J, Gordon SD, Henders AK, Holliday EG, et al., 'Association between endometriosis and the interleukin 1A (ILIA) locus', HUMAN REPRODUCTION, 30 239-248 (2015)
DOI10.1093/humrep/deu267Author URL
CitationsScopus - 2Web of Science - 2
Co-authorsRodney Scott, Liz Holliday
2015Bidarian-Moniri A, Nilsson M, Attia J, Ejnell H, 'Mattress and pillow for prone positioning for treatment of obstructive sleep apnoea', Acta Oto-Laryngologica, 135 271-276 (2015)

Conclusion: The new mattress and pillow for prone positioning (MPP) is efficient in reducing the apnoea-hypopnoea index (AHI) and oxygen desaturation index (ODI) in most patients with obstructive sleep apnoea (OSA), with satisfactory compliance. Objective: The aim of the present study was to evaluate the effect of the prone body and head sleep position on severity of disease in patients with OSA after 4 weeks of adaptation to a mattress and pillow facilitating prone positioning. Methods: Fourteen patients with mild to severe OSA, 11 men and 3 women with a mean AHI of 26 (min, 6; max, 53) and mean ODI of 21 (min, 6; max, 51) were evaluated. Two polysomnographic (PSG) studies were performed. The first PSG study was without any treatment and the second was after 4 weeks of adaptation to the MPP for prone positioning of the body and the head. Results: Mean AHI and ODI decreased from 26 and 21 to 8 and 7, respectively (p < 0.001) with treatment. The mean time spent in the supine position was reduced from 128 to 10 min (p = 0.02) and the prone time increased from 42 to 174 min (p = 0.02) with the MPP. The mean total sleep time was 390 min during the first PSG study night without treatment and 370 min during the second night with the MPP (p = 0.7). Ten patients (71%) reduced their AHI by at least 50% and reached a value < 10 during treatment. All patients managed to sleep on the MPP for > 4 h per night during the 4-week study.

DOI10.3109/00016489.2014.968674
2015Chan JPL, Thalamuthu A, Oldmeadow C, Armstrong NJ, Holliday EG, McEvoy M, et al., 'Genetics of hand grip strength in mid to late life', Age, 37 1-10 (2015)

Hand grip strength (GS) is a predictor of mortality in older adults and is moderately to highly heritable, but no genetic variants have been consistently identified. We aimed to identify single nucleotide polymorphisms (SNPs) associated with GS in middle-aged to older adults using a genome-wide association study (GWAS). GS was measured using handheld dynamometry in community-dwelling men and women aged 55¿85 from the Hunter Community Study (HCS, N = 2088) and the Sydney Memory and Ageing Study (Sydney MAS, N = 541). Genotyping was undertaken using Affymetrix microarrays with imputation to HapMap2. Analyses were performed using linear regression. No genome-wide significant results were observed in HCS nor were any of the top signals replicated in Sydney MAS. Gene-based analyses in HCS identified two significant genes (ZNF295, C2CD2), but these results were not replicated in Sydney MAS. One out of eight SNPs previously associated with GS, rs550942, located near the CNTF gene, was significantly associated with GS (p = 0.005) in the HCS cohort only. Study differences may explain the lack of consistent results between the studies, including the smaller sample size of the Sydney MAS cohort. Our modest sample size also had limited power to identify variants of small effect. Our results suggest that similar to various other complex traits, many genetic variants of small effect size may influence GS. Future GWAS using larger samples and consistent measures may prove more fruitful at identifying genetic contributors for GS in middle-aged to older adults.

DOI10.1007/s11357-015-9745-5
Co-authorsRodney Scott, Christopher Oldmeadow, Liz Holliday, Roseanne Peel
2015Kelly PJ, Baker AL, Deane FP, Callister R, Collins CE, Oldmeadow C, et al., 'Study protocol: a stepped wedge cluster randomised controlled trial of a healthy lifestyle intervention for people attending residential substance abuse treatment.', BMC Public Health, 15 465 (2015)
DOI10.1186/s12889-015-1729-yAuthor URL
Co-authorsRobin Callister, Christopher Oldmeadow, Amanda Baker, Clare Collins
2015Milne E, Greenop KR, Scott RJ, Haber M, Norris MD, Attia J, et al., 'Folate pathway gene polymorphisms, maternal folic acid use, and risk of childhood acute lymphoblastic leukemia', Cancer Epidemiology Biomarkers and Prevention, 24 48-56 (2015)

Background: Several studies suggest that maternal folic acid supplementation before or during pregnancy protects against childhood acute lymphoblastic leukemia (ALL). We investigated associations between ALL risk and folate pathway gene polymorphisms, and their modification by maternal folic acid supplements, in a population-based case-control study (2003-2007). Methods: All Australian pediatric oncology centers provided cases; controls were recruited by national random digit dialing. Data from 392 cases and 535 controls were included. Seven folate pathway gene polymorphisms (MTHFR 677C>T, MTHFR 1298A>C, MTRR 66A>G, MTR 2756 A>G, MTR 5049 C>A, CBS 844 Ins68, and CBS 2199 T>C) were genotyped in children and their parents. Information on prepregnancy maternal folic acid supplement use was collected. ORs were estimated with unconditional logistic regression adjusted for frequency-matched variables and potential confounders. Case-parent trios were also analyzed. Results: There was some evidence of a reduced risk of ALL among children who had, or whose father had, the MTRR 66GG genotype: ORs 0.60 [95% confidence interval (CI) 0.39-0.91] and 0.64 (95% CI, 0.40-1.03), respectively. The ORs for paternal MTHFR 677CT and TT genotypes were 1.41 (95% CI, 1.02-1.93) and 1.81 (95% CI, 1.06-3.07). ORs varied little by maternal folic acid supplementation. Conclusions: Some folate pathway gene polymorphisms in the child or a parent may influence ALL risk. While biologically plausible, underlying mechanisms for these associations need further elucidation. Impact: Folate pathway polymorphisms may be related to risk of childhood ALL, but larger studies are needed for conclusive results.

DOI10.1158/1055-9965.EPI-14-0680
CitationsScopus - 1
Co-authorsRodney Scott
2015Muenchhoff J, Poljak A, Song F, Raftery M, Brodaty H, Duncan M, et al., 'Plasma Protein Profiling of Mild Cognitive Impairment and Alzheimer's Disease Across Two Independent Cohorts', JOURNAL OF ALZHEIMERS DISEASE, 43 1355-1373 (2015)
DOI10.3233/JAD-141266Author URL
CitationsScopus - 1
Co-authorsPeter Schofield
2015Kongtharvonskul J, Anothaisintawee T, McEvoy M, Attia J, Woratanarat P, Thakkinstian A, 'Efficacy and safety of glucosamine, diacerein, and NSAIDs in osteoarthritis knee: A systematic review and network meta-analysis', European Journal of Medical Research, 20 (2015)

Background: To conduct a systematic review and network meta-analysis of randomized controlled trials (RCTs) with the aims of comparing relevant clinical outcomes (that is, visual analog scores (VAS), total and sub-Western Ontario and McMaster Universities Osteoarthritis index (WOMAC) scores, Lequesne algofunctional index, joint space width change, and adverse events) between diacerein, glucosamine, and placebo. Methods: Medline and Scopus databases were searched from inception to 29 August 2014, using PubMed and Scopus search engines and included RCTs or quasi-experimental designs comparing clinical outcomes between treatments. Data were extracted from original studies. A network meta-analysis was performed by applying weight regression for continuous outcomes and a mixed-effect Poisson regression for dichotomous outcomes. Results: Thirty-one of 505 identified studies were eligible. Compared to placebo, glucosamine showed a significant improvement with unstandardized mean differences (UMD) in total WOMAC, pain WOMAC, function WOMAC, and Lequesne score of -2.49 (95% confidence interval (CI) -4.14, -0.83), -0.75 (95% CI: -1.18, -0.32), -4.78 (95% CI: -5.96, -3.59), and -1.03 (95% CI: -1.34, -0.72), respectively. Diacerein clinically improves visual analog scores, function WOMAC, and stiffness WOMAC with UMD values of -2.23 (95% CI: -2.82, -1.64), -6.64 (95% CI: -10.50, -2.78), and -0.68 (95% CI: -1.20, -0.16) when compared to placebo. Conclusions: The network meta-analysis suggests that diacerein and glucosamine are equally efficacious for symptom relief in knee OA, but that the former has more side effects.

DOI10.1186/s40001-015-0115-7
2015Kongtharvonskul J, Anothaisintawee T, McEvoy M, Attia J, Woratanarat P, Thakkinstian A, 'Efficacy and safety of glucosamine, diacerein, and NSAIDs in osteoarthritis knee: a systematic review and network meta-analysis.', European journal of medical research, 20 24 (2015)
DOI10.1186/s40001-015-0115-7
2015Greenop KR, Miller M, Bailey HD, de Klerk NH, Attia J, Kellie SJ, et al., 'Childhood folate, B6, B12, and food group intake and the risk of childhood brain tumors: results from an Australian case¿control study', Cancer Causes and Control, (2015)
DOI10.1007/s10552-015-0562-z
2015Hancock DB, Levy JL, Gaddis NC, Glasheen C, Saccone NL, Page GP, et al., 'Cis-Expression Quantitative Trait Loci Mapping Reveals Replicable Associations with Heroin Addiction in OPRM1.', Biol Psychiatry, (2015)
DOI10.1016/j.biopsych.2015.01.003Author URL
Co-authorsRodney Scott, Liz Holliday
2015Painter JN, O'Mara TA, Batra J, Cheng T, Lose FA, Dennis J, et al., 'Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk', HUMAN MOLECULAR GENETICS, 24 1478-1492 (2015) [C1]
DOI10.1093/hmg/ddu552Author URL
Co-authorsRodney Scott, Katie Ashton, Liz Holliday
2015Vejakama P, Ingsathit A, Attia J, Thakkinstian A, 'Epidemiological study of chronic kidney disease progression: a large-scale population-based cohort study.', Medicine (Baltimore), 94 e475 (2015)
DOI10.1097/MD.0000000000000475Author URL
2015Davies G, Armstrong N, Bis JC, Bressler J, Chouraki V, Giddaluru S, et al., 'Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949).', Mol Psychiatry, 20 183-192 (2015)
DOI10.1038/mp.2014.188Author URL
CitationsWeb of Science - 1
Co-authorsChristopher Oldmeadow, Liz Holliday, Peter Schofield, Rodney Scott
2015Holliday EG, Traylor M, Malik R, Bevan S, Falcone G, Hopewell JC, et al., 'Genetic overlap between diagnostic subtypes of ischemic stroke.', Stroke, 46 615-619 (2015)
DOI10.1161/STROKEAHA.114.007930Author URL
Co-authorsChris Levi, Liz Holliday, Christopher Oldmeadow, Jane Maguire, Rodney Scott, Lisa Lincz
2015Dunn A, Marsden DL, Nugent E, Van Vliet P, Spratt NJ, Attia J, Callister R, 'Protocol variations and six-minute walk test performance in stroke survivors: A systematic review with meta-analysis', Stroke Research and Treatment, 2015 (2015)

Objective. To investigate the use of the six-minute walk test (6MWT) for stroke survivors, including adherence to 6MWT protocol guidelines and distances achieved. Methods. A systematic search was conducted from inception to March 2014. Included studies reported a baseline (intervention studies) or first instance (observational studies) measure for the 6MWT performed by stroke survivors regardless of time after stroke. Results. Of 127 studies (participants n = 6,012) that met the inclusion criteria, 64 were also suitable for meta-analysis. Only 25 studies made reference to the American Thoracic Society (ATS) standards for the 6MWT, and 28 reported using the protocol standard 30 m walkway. Thirty-nine studies modified the protocol walkway, while 60 studies did not specify the walkway used. On average, stroke survivors walked 284 ± 107 m during the 6MWT, which is substantially less than healthy age-matched individuals. The meta-analysis identified that changes to the ATS protocol walkway are associated with reductions in walking distances achieved. Conclusion. The 6MWT is now widely used in stroke studies. The distances achieved by stroke patients indicate substantially compromised walking ability. Variations to the standard 30 m walkway for the 6MWT are common and caution should be used when comparing the values achieved from studies using different walkway lengths.

DOI10.1155/2015/484813
CitationsScopus - 1
Co-authorsRobin Callister, Paulette Vanvliet, Neil Spratt
2015Greenop KR, Hinwood AL, Fritschi L, Scott RJ, Attia J, Ashton LJ, et al., 'Vehicle refuelling, use of domestic wood heaters and the risk of childhood brain tumours: Results from an Australian case-control study', Pediatric Blood and Cancer, 62 229-234 (2015)

The aetiology of childhood brain tumours (CBT) is largely unknown. Damage to germ cells after parental exposure to airborne carcinogens, such as volatile organic compounds and polycyclic aromatic hydrocarbons is one plausible pathway. This analysis aimed to investigate whether parental refuelling of vehicles or the use of domestic wood heaters in key time periods relating to the child's birth was associated with an increased risk of CBT. Procedure: Cases <15 years of age were recruited through 10 paediatric oncology centres around Australia; controls were recruited through nationwide random-digit dialling, frequency matched to cases on age, sex and State of residence. Exposure to refuelling and wood heaters was ascertained through questionnaires from both parents. Odds ratios (ORs) and confidence intervals (CIs) were estimated using unconditional logistic regression, adjusting for relevant covariates. Results: Data were available for 306 case and 950 control families. Paternal refuelling =4times/month was associated with an increased risk of CBT (OR 1.59, 95% CI: 1.11, 2.29), and a dose-dependent trend was observed (P=0.004). No association was seen for maternal refuelling. Use of closed, but not open, wood heaters before (OR 1.51, 95% CI: 1.05, 2.15) and after (OR 1.44, 95% CI: 1.03, 2.01) the child's birth was associated with increased risk of CBT, but dose-response relationships were weak or absent. Conclusions: Paternal refuelling of vehicles =4times/month and the use of closed wood heaters before the child's birth may increase the risk of CBT. Replication in larger studies is needed.

DOI10.1002/pbc.25268
Co-authorsRodney Scott
2015Pundavela J, Roselli S, Faulkner S, Attia J, Scott RJ, Thorne RF, et al., 'Nerve fibers infiltrate the tumor microenvironment and are associated with nerve growth factor production and lymph node invasion in breast cancer', Molecular Oncology, (2015)

Infiltration of the tumor microenvironment by nerve fibers is an understudied aspect of breast carcinogenesis. In this study, the presence of nerve fibers was investigated in a cohort of 369 primary breast cancers (ductal carcinomas in situ, invasive ductal and lobular carcinomas) by immunohistochemistry for the neuronal marker PGP9.5. Isolated nerve fibers (axons) were detected in 28% of invasive ductal carcinomas as compared to only 12% of invasive lobular carcinomas and 8% of ductal carcinomas in situ (p=0.0003). In invasive breast cancers, the presence of nerve fibers was observed in 15% of lymph node negative tumors and 28% of lymph node positive tumors (p=0.0031), indicating a relationship with the metastatic potential. In addition, there was an association between the presence of nerve fibers and the expression of nerve growth factor (NGF) in cancer cells (p=0.0001). Invitro, breast cancer cells were able to induce neurite outgrowth in PC12 cells, and this neurotrophic activity was partially inhibited by anti-NGF blocking antibodies. In conclusion, infiltration by nerve fibers is a feature of the tumor microenvironment that is associated with aggressiveness and involves NGF production by cancer cells. The potential participation of nerve fibers in breast cancer progression needs to be further considered.

DOI10.1016/j.molonc.2015.05.001
Co-authorsRodney Scott, Hubert Hondermarck, Rick Thorne, Phillip Jobling, Marjorie Walker
2015Greenop KR, Miller M, Bailey HD, de Klerk NH, Attia J, Kellie SJ, et al., 'Childhood folate, B6, B12, and food group intake and the risk of childhood brain tumors: results from an Australian case¿control study', Cancer Causes and Control, 26 871-879 (2015)

Purpose: The etiology of childhood brain tumors (CBT) is poorly understood, but dietary factors could be involved. In this case¿control study of CBT, the possible associations of childhood intake of dietary and supplemental folate, vitamin B6, and vitamin B12 with the risk of CBT were investigated, along with various food groups. Methods: Cases diagnosed between 2005 and 2010 were identified from 10 pediatric oncology centers in Australia and controls by nationwide random-digit dialling. For study children of ages 3¿14¿years, diet in the year before diagnosis (or recruitment) was assessed using food frequency questionnaires. Folate intake was adjusted for bioavailability, and dietary micronutrient intake was energy-adjusted. Micronutrients and food groups were analyzed using logistic regression adjusting for relevant confounders. Principal components analysis was conducted to assess food group intake patterns for analysis. Results: Food and micronutrient data were available for 216 cases and 523 controls. Folate intake was associated with a reduced risk of CBT overall (odds ratio for highest tertile vs. lowest: 0.63, 95¿% confidence interval 0.41, 0.97) and particularly low-grade gliomas (odds ratio for highest tertile vs. lowest: 0.52, 95¿% confidence interval 0.29, 0.92). Vitamin B6 and B12 intake was not associated with CBT risk, nor was processed meat. Conclusions: High folate intake during childhood may reduce the risk of CBT. This potentially important finding needs to be corroborated in other studies. If replicated, these results could have important implications for public health recommendations regarding diet during childhood.

DOI10.1007/s10552-015-0562-z
2015van Dyk M, Mangoni AA, McEvoy M, Attia JR, Sorich MJ, Rowland A, 'Targeted arginine metabolomics: A rapid, simple UPLC-QToF-MS(E) based approach for assessing the involvement of arginine metabolism in human disease.', Clin Chim Acta, 447 59-65 (2015)
DOI10.1016/j.cca.2015.05.014Author URL
2015Thomas LC, Rivett DA, Attia JR, Levi C, 'Risk Factors and Clinical Presentation of Cervical Arterial Dissection: Preliminary Results of a Prospective Case-Control Study.', J Orthop Sports Phys Ther, 45 503-511 (2015)
DOI10.2519/jospt.2015.5877Author URL
Co-authorsDarren Rivett
2015Denham JW, Steigler A, Joseph D, Lamb DS, Spry NA, Duchesne G, et al., 'Radiation dose escalation or longer androgen suppression for locally advanced prostate cancer? Data from the TROG 03.04 RADAR trial.', Radiother Oncol, (2015)
DOI10.1016/j.radonc.2015.05.016Author URL
Co-authorsLiz Holliday, Christopher Oldmeadow, Allison Steigler
2015Greenop KR, Scott RJ, Attia J, Bower C, de Klerk NH, Norris MD, et al., 'Folate pathway gene polymorphisms and risk of childhood brain tumors: results from an Australian case-control study.', Cancer Epidemiol Biomarkers Prev, 24 931-937 (2015)
DOI10.1158/1055-9965.EPI-14-1248Author URL
2015Abdullah N, Abdul Murad NA, Attia J, Oldmeadow C, Mohd Haniff EA, Syafruddin SE, et al., 'Characterizing the genetic risk for Type 2 diabetes in a Malaysian multi-ethnic cohort.', Diabet Med, (2015)
DOI10.1111/dme.12735Author URL
Co-authorsLiz Holliday, Christopher Oldmeadow
2015Hiles SA, Baker AL, de Malmanche T, McEvoy M, Boyle M, Attia J, 'The role of inflammatory markers in explaining the association between depression and cardiovascular hospitalisations.', J Behav Med, (2015)
DOI10.1007/s10865-015-9637-2Author URL
Co-authorsAmanda Baker
2015Sapkota Y, Attia J, Gordon SD, Henders AK, Holliday EG, Rahmioglu N, et al., 'Genetic burden associated with varying degrees of disease severity in endometriosis.', Mol Hum Reprod, 21 594-602 (2015)
DOI10.1093/molehr/gav021Author URL
Co-authorsLiz Holliday
2015Ibrahim-Verbaas CA, Bressler J, Debette S, Schuur M, Smith AV, Bis JC, et al., 'GWAS for executive function and processing speed suggests involvement of the CADM2 gene.', Mol Psychiatry, (2015)
DOI10.1038/mp.2015.37Author URL
Co-authorsPeter Schofield, Liz Holliday
2015Kelly AG, Attia J, 'Balancing access and quality in comprehensive stroke care.', Neurology, 84 1188-1189 (2015)
DOI10.1212/WNL.0000000000001405Author URL
2015Roselli S, Pundavela J, Demont Y, Faulkner S, Keene S, Attia J, et al., 'Sortilin is associated with breast cancer aggressiveness and contributes to tumor cell adhesion and invasion.', Oncotarget, 6 10473-10486 (2015)
Author URL
Co-authorsHubert Hondermarck, Xu Zhang, Marjorie Walker
2014Vashum KP, McEvoy M, Milton AH, McElduff P, Hure A, Byles J, Attia J, 'Dietary zinc is associated with a lower incidence of depression: findings from two Australian cohorts.', J Affect Disord, 166 249-257 (2014) [C1]
DOI10.1016/j.jad.2014.05.016Author URL
CitationsScopus - 4Web of Science - 6
Co-authorsJulie Byles, Alexis Hure, Milton Hasnat
2014Oldmeadow C, Mossman D, Evans TJ, Holliday EG, Tooney PA, Cairns MJ, et al., 'Combined analysis of exon splicing and genome wide polymorphism data predict schizophrenia risk loci.', J Psychiatr Res, 52 44-49 (2014) [C1]
DOI10.1016/j.jpsychires.2014.01.011Author URL
CitationsScopus - 1Web of Science - 1
Co-authorsMurray Cairns, Paul Tooney, Christopher Oldmeadow, Liz Holliday, Rodney Scott
2014Paul CL, Levi CR, D'Este CA, Parsons MW, Bladin CF, Lindley RI, et al., 'Thrombolysis ImPlementation in Stroke (TIPS): Evaluating the effectiveness of a strategy to increase the adoption of best evidence practice - protocol for a cluster randomised controlled trial in acute stroke care', Implementation Science, 9 (2014) [C3]

Background: Stroke is a leading cause of death and disability internationally. One of the three effective interventions in the acute phase of stroke care is thrombolytic therapy with tissue plasminogen activator (tPA), if given within 4.5 hours of onset to appropriate cases of ischaemic stroke.Objectives: To test the effectiveness of a multi-component multidisciplinary collaborative approach compared to usual care as a strategy for increasing thrombolysis rates for all stroke patients at intervention hospitals, while maintaining accepted benchmarks for low rates of intracranial haemorrhage and high rates of functional outcomes for both groups at three months.Methods and design: A cluster randomised controlled trial of 20 hospitals across 3 Australian states with 2 groups: multi- component multidisciplinary collaborative intervention as the experimental group and usual care as the control group. The intervention is based on behavioural theory and analysis of the steps, roles and barriers relating to rapid assessment for thrombolysis eligibility; it involves a comprehensive range of strategies addressing individual-level and system-level change at each site. The primary outcome is the difference in tPA rates between the two groups post-intervention. The secondary outcome is the proportion of tPA treated patients in both groups with good functional outcomes (modified Rankin Score (mRS <2) and the proportion with intracranial haemorrhage (mRS =2), compared to international benchmarks.Discussion: TIPS will trial a comprehensive, multi-component and multidisciplinary collaborative approach to improving thrombolysis rates at multiple sites. The trial has the potential to identify methods for optimal care which can be implemented for stroke patients during the acute phase. Study findings will include barriers and solutions to effective thrombolysis implementation and trial outcomes will be published whether significant or not.Trial registration: Australian New Zealand Clinical Trials Registry: ACTRN12613000939796. © 2014 Paul et al.; licensee BioMed Central Ltd.

DOI10.1186/1748-5908-9-38
CitationsWeb of Science - 1
Co-authorsMark Parsons, Catherine Deste, Chris Paul, Rob Sanson-Fisher, Chris Levi, Frans Henskens
2014Squance ML, Guest M, Reeves G, Attia J, Bridgman H, 'Exploring lifetime occupational exposure and SLE flare: a patient-focussed pilot study.', Lupus Science & Medicine, 1 1-9 (2014) [C1]
DOI10.1136/lupus-2014-000023
Co-authorsMaya Guest
2014Springelkamp H, Höhn R, Mishra A, Hysi PG, Khor C-C, Loomis SJ, et al., 'Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process', Nature Communications, 5 (2014) [C1]

Glaucoma is characterized by irreversible optic nerve degeneration and is the most frequent cause of irreversible blindness worldwide. Here, the International Glaucoma Genetics Consortium conducts a meta-analysis of genome-wide association studies of vertical cup-disc ratio (VCDR), an important disease-related optic nerve parameter. In 21,094 individuals of European ancestry and 6,784 individuals of Asian ancestry, we identify 10 new loci associated with variation in VCDR. In a separate risk-score analysis of five case-control studies, Caucasians in the highest quintile have a 2.5-fold increased risk of primary open-angle glaucoma as compared with those in the lowest quintile. This study has more than doubled the known loci associated with optic disc cupping and will allow greater understanding of mechanisms involved in this common blinding condition.

DOI10.1038/ncomms5883
CitationsScopus - 8
Co-authorsLiz Holliday, Rodney Scott
2014Lai JS, Attia JR, McEvoy M, Hure AJ, 'Biochemical Validation of the Older Australian¿s Food Frequency Questionnaire Using Carotenoids and Vitamin E', Nutrients, 6 4906-4917 (2014)
DOI10.3390/nu6114906
Co-authorsAlexis Hure
2014Traylor M, Mäkelä KM, Kilarski LL, Holliday EG, Devan WJ, Nalls MA, et al., 'A novel MMP12 locus is associated with large artery atherosclerotic stroke using a genome-wide age-at-onset informed approach.', PLoS Genet, 10 e1004469 (2014) [C1]
DOI10.1371/journal.pgen.1004469Author URL
CitationsScopus - 4Web of Science - 4
Co-authorsJane Maguire, Chris Levi, Liz Holliday
2014Sotgia S, Zinellu A, Mangoni AA, Pintus G, Attia J, Carru C, McEvoy M, 'Clinical and biochemical correlates of serum L-ergothioneine concentrations in community-dwelling middle-aged and older adults', PLoS ONE, 9 (2014) [C1]

Background: Despite the increasing interest towards the biological role of L-ergothioneine, little is known about the serum concentrations of this unusual aminothiol in older adults. We addressed this issue in a representative sample of community-dwelling middle-aged and older adults. Methods: Body mass index, estimated glomerular filtration rate, serum concentrations of L-ergothioneine, taurine, homocysteine, cysteine, glutathione, cysteinylglycine, and glutamylcysteine were evaluated in 439 subjects (age 55-85 years) randomly selected from the Hunter Community Study. Results: Median L-ergothioneine concentration in the entire cohort was 1.01 IQR 0.78-1.33 µmol/L. Concentrations were not affected by gender (P = 0.41) or by presence of chronic medical conditions (P = 0.15). By considering only healthy subjects, we defined a reference interval for L-ergothioneine serum concentrations from 0.36 (90% CI 0.31-0.44) to 3.08 (90% CI 2.45-3.76) µmol/L. Using stepwise multiple linear regression analysis L-ergothioneine was negatively correlated with age (rpartial = 20.15; P = 0.0018) and with glutamylcysteine concentrations (rpartial = 20.13; P = 0.0063). Conclusions: A thorough analysis of serum L-ergothioneine concentrations was performed in a large group of community-dwelling middle-aged and older adults. Reference intervals were established. Age and glutamylcysteine were independently negatively associated with L-ergothioneine serum concentration. © 2014 Sotgia et al.

DOI10.1371/journal.pone.0084918
2014Vashum KP, McEvoy M, Milton AH, Islam MR, Hancock S, Attia J, 'Is serum zinc associated with pancreatic beta cell function and insulin sensitivity in pre-diabetic and normal individuals? Findings from the hunter community study', PLoS ONE, 9 (2014) [C1]

Aim: To determine if there is a difference in serum zinc concentration between normoglycaemic, pre-diabetic and type-2 diabetic groups and if this is associated with pancreatic beta cell function and insulin sensitivity in the former 2 groups. Method: Cross sectional study of a random sample of older community-dwelling men and women in Newcastle, New South Wales, Australia. Beta cell function, insulin sensitivity and insulin resistance were calculated for normoglycaemic and prediabetes participants using the Homeostasis Model Assessment (HOMA-2) calculator. Result: A total of 452 participants were recruited for this study. Approximately 33% (N = 149) had diabetes, 33% (N = 151) had prediabetes and 34% (N = 152) were normoglycaemic. Homeostasis Model Assessment (HOMA) parameters were found to be significantly different between normoglycaemic and prediabetes groups (p<0.001). In adjusted linear regression, higher serum zinc concentration was associated with increased insulin sensitivity (p = 0.01) in the prediabetic group. There was also a significant association between smoking and worse insulin sensitivity. Conclusion: Higher serum zinc concentration is associated with increased insulin sensitivity. Longitudinal studies are required to determine if low serum zinc concentration plays a role in progression from pre-diabetes to diabetes. © 2014 Vashum et al.

DOI10.1371/journal.pone.0083944
CitationsScopus - 1Web of Science - 1
Co-authorsMilton Hasnat
2014Evans TJ, Milne E, Anderson D, de Klerk NH, Jamieson SE, Talseth-Palmer BA, et al., 'Confirmation of childhood acute lymphoblastic leukemia variants, ARID5B and IKZF1, and interaction with parental environmental exposures.', PLoS One, 9 e110255 (2014) [C1]
DOI10.1371/journal.pone.0110255Author URL
CitationsScopus - 1Web of Science - 1
Co-authorsNikola Bowden, Rodney Scott, Liz Holliday, Bente Talseth-Palmer
2014Lai JS, Hiles S, Bisquera A, Hure AJ, McEvoy M, Attia J, 'A systematic review and meta-analysis of dietary patterns and depression in community-dwelling adults', AMERICAN JOURNAL OF CLINICAL NUTRITION, 99 181-197 (2014) [C1]
DOI10.3945/ajcn.113.069880Author URL
CitationsScopus - 22Web of Science - 23
Co-authorsAlexis Hure
2014Holliday EG, Attia J, Hancock S, Koloski N, McEvoy M, Peel R, et al., 'Genome-wide association study identifies two novel genomic regions in irritable bowel syndrome', American Journal of Gastroenterology, 109 770-772 (2014) [C1]
DOI10.1038/ajg.2014.56
CitationsScopus - 2Web of Science - 1
Co-authorsNicholas Talley, Roseanne Peel, Rodney Scott, Liz Holliday
2014White JH, Patterson K, Jordan L-A, Magin P, Attia J, Sturm JW, 'The experience of urinary incontinence in stroke survivors: A follow-up qualitative study', CANADIAN JOURNAL OF OCCUPATIONAL THERAPY-REVUE CANADIENNE D ERGOTHERAPIE, 81 124-134 (2014) [C1]
DOI10.1177/0008417414527257Author URL
Co-authorsParker Magin
2014Ho YM, Smith SR, Pockney P, Lim P, Attia J, 'A Meta-analysis on the Effect of Sham Feeding Following Colectomy: Should Gum Chewing Be Included in Enhanced Recovery After Surgery Protocols?', DISEASES OF THE COLON & RECTUM, 57 115-126 (2014) [C1]
DOI10.1097/DCR.0b013e3182a665beAuthor URL
CitationsScopus - 4Web of Science - 3
2014Robertson J, Pearson S-A, Attia JR, 'How well do NSW hospital data identify cases of heart failure?', MEDICAL JOURNAL OF AUSTRALIA, 200 25-25 (2014) [C3]
DOI10.5694/mja13.10207Author URL
2014Holliday EG, Traylor M, Malik R, Bevan S, Maguire J, Koblar SA, et al., 'Polygenic Overlap Between Kidney Function and Large Artery Atherosclerotic Stroke', STROKE, 45 3508-+ (2014) [C1]
DOI10.1161/STROKEAHA.114.006609Author URL
Co-authorsChris Levi, Rodney Scott, Jane Maguire, Christopher Oldmeadow, Liz Holliday
2014Golledge J, Clancy P, Maguire J, Lincz L, Koblar S, Mcevoy M, et al., 'Plasma angiopoietin-1 is lower after ischemic stroke and associated with major disability but not stroke incidence', Stroke, 45 1064-1068 (2014) [C1]
DOI10.1161/STROKEAHA.113.004339
CitationsScopus - 1
Co-authorsJane Maguire, Chris Levi, Lisa Lincz
2014Iseme RA, McEvoy M, Kelly B, Agnew L, Attia J, Walker FR, 'Autoantibodies and depression. Evidence for a causal link?', Neuroscience and Biobehavioral Reviews, 40 62-79 (2014) [C1]

Depression is a leading contributor to the global burden of diseases. Despite advances in research, challenges still exist in managing this disorder. Sufferers of autoimmune diseases are often observed to suffer from depression more often than healthy individuals, an association that cannot be completely accounted for by the impact of the disease on the individual. An association between autoimmunity and depressive symptoms also appears to exist in populations with subclinical symptoms. Moreover, researchers have successfully developed murine models illustrating the ability of autoantibodies to induce depressive-like symptoms. This paper will provide an overview of the association between autoantibodies and occurrence of depressive symptoms. Though current evidence appears to support a role for autoantibodies in the pathogenesis of depression, the majority of studies have examined this relationship cross-sectionally, therefore failing to establish a temporal association. Nonetheless, this novel theory meshes with older and newer neurochemical theories of depression. A better understanding of the immuno-pathogenesis underlying depression presents opportunities for more targeted treatment approaches and more timely and appropriate measures of detection. © 2014 Elsevier Ltd.

DOI10.1016/j.neubiorev.2014.01.008
CitationsScopus - 5Web of Science - 2
Co-authorsBrian Kelly, Rohan Walker
2014Quilty S, Valler D, Attia J, 'Rural general physicians: Improving access and reducing costs of health care in the bush', Australian Health Review, 38 420-424 (2014) [C1]

Objective To assess the effectiveness of the introduction of a trainee specialist physician into the workforce mix of a rural hospital in the Northern Territory. Methods A retrospective review comparing clinical and non-clinical outcomes during two corresponding 6-month periods in 2011 and 2012, before and after a FRACP Trainee in General and Acute Care Medicine commenced employment in the hospital. Results There was a significant reduction of 18% in total length of stay of admitted adult patients, with a 23% reduction of inter-hospital transfers and a 43% reduction of total aeromedical evacuations after the introduction of the trainee specialist. Although there was a 9% increase in patients presenting to the emergency department, there was a 9% reduction in total adult admissions. There was no change in the overall in-patient mortality rate; however, there was a significant change in the location of death, with an increase in patients dying in Katherine Hospital and a reciprocal decrease in death rate in those who had been transferred to Royal Darwin Hospital after the arrival of the trainee Conclusions The addition of an Advanced Trainee in General Medicine led to a significant change in the capacity of the hospital to care for unwell and complex patients. The role of the hospital in the care of dying patients was redefined and allowed many more people to pass away closer to their community and families. There were considerable savings at Katherine Hospital in terms of reduced bed pressure, reduced hospital bypass behaviour and reduced inter-hospital transfers, and these translated into significant benefits for the tertiary referral hospital in Darwin. A rural general physician can greatly value add to the capacity of a rural hospital and is a highly effective mechanism for reducing the disparities in healthcare access for rural and Indigenous patients. What is known about this topic? There is little research about the clinical and non-clinical impact of the addition of general speciality clinicians into the workforce of rural hospitals. Although there are several regional hospitals in Australia that have general specialists (i.e. emergency department physicians, general physicians and surgeons) and sub-specialists where the volume of patients is adequate to support such a workforce, there has been no published assessment of the impact of the addition of such speciality services. What does this paper add? This paper provides evidence of the cost-effectiveness of the addition of a specialist general physician to the workforce of a remote hospital servicing a large Indigenous population with very high burdens of acute and chronic illnesses in the Northern Territory. The paper demonstrates the potential to significantly add capacity to a rural or regional hospital by moving general speciality care to the hospital rather than, or in addition to, providing other methods of speciality and sub-speciality health care delivery. What are the implications for practitioners? The implications of this paper are that a significantly cost-effective means of addressing health care delivery to rural and remote populations is through the addition of appropriately trained general specialists such as emergency department physicians, general physicians and general surgeons. The implications extend to broader workforce development policies for education providers, speciality colleges and state and federal governments. © AHHA 2014.

DOI10.1071/AH13197
2014Wang JJ, Buitendijk GHS, Rochtchina E, Lee KE, Klein BEK, Van Duijn CM, et al., 'Genetic susceptibility, dietary antioxidants, and long-term incidence of age-related macular degeneration in two populations', Ophthalmology, 121 667-675 (2014)
DOI10.1016/j.ophtha.2013.10.017
CitationsScopus - 2
Co-authorsLiz Holliday, Wayne Smith
2014Wang JJ, Buitendijk GHS, Rochtchina E, Lee KE, Klein BEK, Van Duijn CM, et al., 'Genetic susceptibility, dietary antioxidants, and long-term incidence of age-related macular degeneration in two populations', Ophthalmology, 121 667-675 (2014) [C1]

Objective To examine effect modification between genetic susceptibility to age-related macular degeneration (AMD) and dietary antioxidant or fish consumption on AMD risk. Design Pooled data analysis of population-based cohorts. Participants Participants from the Blue Mountains Eye Study (BMES) and Rotterdam Study (RS). Methods Dietary intakes of antioxidants (lutein/zeaxanthin [LZ], ß-carotene, and vitamin C), long-chain omega-3 polyunsaturated fatty acids, and zinc were estimated from food frequency questionnaires. The AMD genetic risk was classified according to the number of risk alleles of CFH (rs1061170) or ARMS2 (rs10490924) as low (no or 1 risk allele) or high (=2 risk alleles). Interactions between dietary intake and genetic risk levels were assessed. Associations between dietary intake and AMD risk were assessed comparing the highest with the 2 lower intake tertiles by genetic risk subgroups using discrete logistic regression, conducted in each study separately and then using pooled data. Participants without AMD lesions at any visit were controls. We adjusted for age and sex in analyses of each cohort sample and for smoking status and study site in pooled-data analyses. Main Outcome Measures All 15-year incident late AMD cases were confirmed by chief investigators of the Beaver Dam Eye Study, BMES, and RS. Intergrader reproducibility was assessed in an early AMD subsample, with 86.4% agreement between BMES and RS graders, allowing for a 1-step difference on a 5-step AMD severity scale. Results In pooled data analyses, we found significant interaction between AMD genetic risk status and LZ intake (P = 0.0009) but nonsignificant interactions between genetic risk status and weekly fish consumption (P = 0.05) for risk of any AMD. Among participants with high genetic risk, the highest intake tertile of LZ was associated with a >20% reduced risk of early AMD, and weekly consumption of fish was associated with a 40% reduced risk of late AMD. No similar association was evident among participants with low genetic risk. No interaction was detected between ß-carotene or vitamin C and genetic risk status. Conclusions Protection against AMD from greater LZ and fish consumption in persons with high genetic risk based on 2 major AMD genes raises the possibility of personalized preventive interventions. ©2014 by the American Academy of Ophthalmology.

DOI10.1016/j.ophtha.2013.10.017
CitationsScopus - 3Web of Science - 5
Co-authorsLiz Holliday, Wayne Smith
2014Greenop KR, de Klerk NH, Bower C, Milne E, Miller M, Scott RJ, et al., 'Maternal Dietary Intake of Folate and Vitamins B6 and B12 During Pregnancy and Risk of Childhood Brain Tumors', Nutrition and Cancer, (2014) [C1]

Childhood brain tumors (CBT) are the second most common childhood cancers, yet their etiology is largely unknown. We investigated whether maternal gestational intake of folate and vitamins B6 and B12 was associated with CBT risk in a nationwide case-control study conducted 2005-2010. Case children 0-14 years were recruited from all 10 Australian pediatric oncology centers. Control children were recruited by national random digit dialing, frequency matched to cases on age, sex, and state of residence. Dietary intake was ascertained using food frequency questionnaires and adjusted for total energy intake. Data from 293 case and 726 control mothers were analyzed using unconditional logistic regression. The odds ratio (OR) for the highest versus lowest tertile of folate intake was 0.70 [95% confidence interval (CI): 0.48, 1.02]. The ORs appeared lower in mothers who drank alcohol during pregnancy (OR = 0.45, 95% CI: 0.22, 0.93), mothers who took folic acid (OR = 0.67, 95% CI: 0.42, 1.06) or B6/B12 supplements (OR = 0.51, 95% CI: 0.25, 1.06) and in children younger than 5 years (OR = 0.50, 95% CI: 0.27, 0.93). These findings are consistent with folate's crucial role in maintenance of genomic integrity and DNA methylation. Dietary intake of B6 and B12 was not associated with risk of CBT. © 2014 Copyright © Taylor & Francis Group, LLC.

DOI10.1080/01635581.2014.916326
CitationsScopus - 4Web of Science - 4
Co-authorsRodney Scott
2014Thakkinstian A, Chailurkit L, Warodomwichit D, Ratanachaiwong W, Yamwong S, Chanprasertyothin S, et al., 'Causal relationship between body mass index and fetuin-A level in the asian population: A bidirectional mendelian randomization study', Clinical Endocrinology, 81 197-203 (2014) [C1]

Objective Fetuin-A is associated with body mass index (BMI) as well as components of the metabolic syndrome. However, it is unclear if fetuin-A affects BMI or the other way around. We therefore assessed the causal association between fetuin-A and BMI or vice versa, utilizing a bidirectional Mendelian randomization approach. Design and Methods This was a study of 2558 subjects from the Electricity Generating Authority of Thailand (EGAT) cohort. Two polymorphisms, that is, rs2248690 in the alpha2-Hereman-Schmid glycoprotein (AHSG) gene and rs9939609 in the fat mass and obesity-Associated (FTO) gene were genotyped. Bidirectional causal models were constructed using a two-stage least-square instrumental variable (IV) regression. First, rs2248690 locus was used as the instrumental variable for the effect of circulating fetuin-A on BMI, and then, the FTO rs9939609 locus was used as the instrumental variable for the effect of BMI on circulating fetuin-A. Results Among the 2558 subjects, the prevalence of the minor AHSG (T) and FTO (A) alleles was 17·9% and 22·1%, respectively. The AHSG rs2248690 locus was highly related to serum fetuin-A levels (P < 0·001). Likewise, the FTO rs9939609 locus and BMI were highly associated (P < 0·001). Mendelian randomization analyses showed that circulating fetuin-A, instrumented by the AHSG rs2248690 locus, was associated with BMI (coefficient = 2·26; 95% CI: 0·39, 4·12). In contrast, BMI, instrumented by the FTO rs9939609 locus, was not associated with circulating fetuin-A (coefficient = 0·0007; 95% CI: -0·0242, 0·0256). Conclusion Our findings suggest a causal association leading from circulating fetuin-A to BMI. There was no evidence of reverse causality from BMI to fetuin-A. © 2013 John Wiley & Sons Ltd.

DOI10.1111/cen.12303
CitationsScopus - 2Web of Science - 2
2014Thakkinstian A, Chailurkit L, Warodomwichit D, Yamwong S, Sritara P, Ongphiphadhanakul B, et al., 'Causal relationship between body mass index and fetuin-A level in the asian population: A bidirectional mendelian randomization study', Clinical Endocrinology, 81 197-203 (2014)
DOI10.1111/cen.12303
CitationsScopus - 1
2014Joshy G, Korda RJ, Attia J, Liu B, Bauman AE, Banks E, 'Body mass index and incident hospitalisation for cardiovascular disease in 158 546 participants from the 45 and Up Study', International Journal of Obesity, 38 848-856 (2014) [C1]

Objective: To investigate the relationship between fine gradations in body mass index (BMI) and risk of hospitalisation for different types of cardiovascular disease (CVD). Design, Subjects and Methods: The 45 and Up Study is a large-scale Australian cohort study initiated in 2006. Self-reported data from 158 546 individuals with no history of CVD were linked prospectively to hospitalisation and mortality data. Hazard ratios (HRs) of incident hospitalisation for specific CVD diagnoses in relation to baseline BMI categories were estimated using Cox regression, adjusting for age, sex, region of residence, income, education, smoking, alcohol intake and health insurance status. Results: There were 9594 incident CVD admissions over 583 100 person-years among people with BMI=20 kg m-2, including 3096 for ischaemic heart disease (IHD), 1373 for stroke, 411 for peripheral vascular disease (PVD) and 320 for heart failure. The adjusted HR of hospitalisation for all CVD diagnoses combined increased significantly with increasing BMI (P(trend) <0.0001)). The HR of IHD hospitalisation increased by 23% (95% confidence interval (95% CI): 18-27%) per 5 kg m-2 increase in BMI (compared to BMI 20.0-22.49 kg m-2, HR (95% CI) for BMI categories were: 22.5-24.99=1.25 (1.08-1.44); 25-27.49=1.43 (1.24-1.65); 27.5-29.99=1.64 (1.42-1.90); 30-32.49=1.63 (1.39-1.91) and 32.5-50=2.10 (1.79-2.45)). The risk of hospitalisation for heart failure showed a significant, but nonlinear, increase with increasing BMI. No significant increase was seen with above-normal BMI for stroke or PVD. For other specific classifications of CVD, HRs of hospitalisation increased significantly with increasing BMI for: hypertension; angina; acute myocardial infarction; chronic IHD; pulmonary embolism; non-rheumatic aortic valve disorders; atrioventricular and left bundle-branch block; atrial fibrillation and flutter; aortic aneurysm; and phlebitis and thrombophlebitis. Conclusion: The risk of hospitalisation for a wide range of CVD subtypes increases with relatively fine increments in BMI. Obesity prevention strategies are likely to benefit from focusing on bringing down the mean BMI at the population level, in addition to targeting those with a high BMI. © 2014 Macmillan Publishers Limited All rights reserved.

DOI10.1038/ijo.2013.192
CitationsScopus - 5Web of Science - 4
2014Joshy G, Korda RJ, Banks E, Attia J, Liu B, Bauman AE, 'Body mass index and incident hospitalisation for cardiovascular disease in 158 546 participants from the 45 and Up Study', International Journal of Obesity, 38 848-856 (2014)
DOI10.1038/ijo.2013.192
CitationsScopus - 1
2014De Vivo I, Prescott J, Setiawan VW, Olson SH, Wentzensen N, Attia J, et al., 'Genome-wide association study of endometrial cancer in E2C2', HUMAN GENETICS, 133 211-224 (2014) [C1]
DOI10.1007/s00439-013-1369-1Author URL
CitationsScopus - 4Web of Science - 6
Co-authorsLiz Holliday, Rodney Scott
2014Moir-Meyer GL, Pearson JF, Lose F, The ANECSG, Scott RJ, McEvoy M, et al., 'Rare germline copy number deletions of likely functional importance are implicated in endometrial cancer predisposition', Human Genetics, (2014)

Endometrial cancer is the most common invasive gynaecological cancer in women, and relatively little is known about inherited risk factors for this disease. This is the first genome-wide study to explore the role of common and rare germline copy number variants (CNVs) in predisposition to endometrial cancer. CNVs were called from germline DNA of 1,209 endometrioid endometrial cancer cases and 528 cancer-unaffected female controls. Overall CNV load of deletions or DNA gains did not differ significantly between cases and controls (P > 0.05), but cases presented with an excess of rare germline deletions overlapping likely functional genomic regions including genes (P = 8 × 10-10), CpG islands (P = 1 × 10-7) and sno/miRNAs regions (P = 3 × 10-9). On average, at least one additional gene and two additional CpG islands were disrupted by rare deletions in cases compared to controls. The most pronounced difference was that over 30 sno/miRNAs were disrupted by rare deletions in cases for every single disruption event in controls. A total of 13 DNA repair genes were disrupted by rare deletions in 19/1,209 cases (1.6 %) compared to one gene in 1/528 controls (0.2 %; P = 0.007), and this increased DNA repair gene loss in cases persisted after excluding five individuals carrying CNVs disrupting mismatch repair genes MLH1, MSH2 and MSH6 (P = 0.03). There were 34 miRNA regions deleted in at least one case but not in controls, the most frequent of which encompassed hsa-mir-661 and hsa-mir-203. Our study implicates rare germline deletions of functional and regulatory regions as possible mechanisms conferring endometrial cancer risk, and has identified specific regulatory elements as candidates for further investigation.

DOI10.1007/s00439-014-1507-4
Co-authorsRodney Scott, Liz Holliday
2014Williams FMK, Carter AM, Hysi PG, Surdulescu G, Hodgkiss D, Soranzo N, et al., 'Ischemic stroke is associated with the ABO locus: The EuroCLOT study (vol 73, pg 16, 2013)', ANNALS OF NEUROLOGY, 75 166-167 (2014)
DOI10.1002/ana.24105Author URL
Co-authorsChris Levi, Liz Holliday, Rodney Scott
2014Johnson NA, Kypri K, Latter J, McElduff P, Saunders JB, Saitz R, et al., 'Prevalence of unhealthy alcohol use in hospital outpatients', Drug and Alcohol Dependence, 144 270-273 (2014)
DOI10.1016/j.drugalcdep.2014.08.014
Co-authorsLuke Wolfenden, Joanna Latter, Kypros Kypri, Natalie Johnson
2014Johnson NA, Kypri K, Latter J, McElduff P, Saunders JB, Saitz R, et al., 'Prevalence of unhealthy alcohol use in hospital outpatients', Drug and Alcohol Dependence, 144 270-273 (2014) [C1]

Background: Few studies have examined the prevalence of unhealthy alcohol use in the hospital outpatient setting. Our aim was to estimate the prevalence of unhealthy alcohol use among patients attending a broad range of outpatient clinics at a large public hospital in Australia. Methods: Adult hospital outpatients were invited to complete the Alcohol Use Disorders Identification Test Consumption questions (AUDIT-C) using an iPad as part of a randomised trial testing the efficacy of alcohol electronic screening and brief intervention. Unhealthy alcohol use was defined as an AUDIT-C score =5 among men and =4 among women. Results: Sixty percent (3616/6070) of invited hospital outpatients consented, of whom 89% (3206/3616) provided information on their alcohol consumption (either reported they had not consumed any alcohol in the last 12 months or completed the AUDIT-C). The prevalence of unhealthy alcohol use was 34.7% (95% confidence interval [CI]: 33.0-36.3%). The prevalence among men aged 18-24 years, 25-39 years, 40-59 years and 60 years and older, was 74.4% (95% CI: 68.4-80.4%), 54.3% (95% CI: 48.7-59.8%), 44.1% (95% CI: 39.9-48.3%), and 27.0% (95% CI: 23.6-30.4%), respectively (43.1% overall; 95% CI: 40.8-45.5%). The prevalence among women aged 18-24 years, 25-39 years, 40-59 years, and 60 years and older, was 48.6% (95% CI: 39.2-58.1%), 36.9% (95% CI: 31.2-42.6%), 25.2% (95% CI: 21.5-29.0%) and 14.5% (95% CI: 11.7-17.3%), respectively (24.9% overall; 95% CI: 22.7-27.1%). Conclusion: A large number of hospital outpatients who are not currently seeking treatment for their drinking could benefit from effective intervention in this setting.

DOI10.1016/j.drugalcdep.2014.08.014
CitationsScopus - 1
Co-authorsJoanna Latter, Luke Wolfenden, Kypros Kypri, Natalie Johnson
2014Woratanarat P, Thaveeratitharm C, Woratanarat T, Angsanuntsukh C, Attia J, Thakkinstian A, 'Meta-analysis of hypercoagulability genetic polymorphisms in perthes disease', Journal of Orthopaedic Research, 32 1-7 (2014) [C1]

Perthes disease is an osteonecrosis of the femoral epiphysis with unclear etiology. This study aimed to systematically review the association between genetic determinants of hypercoagulability (Factor V Leiden, prothrombin II, and methylenetetrahydrofolate reductase; MTHFR) and Perthes disease. PubMed and Scopus searched from inception to January 2012, data extraction and quality assessment were performed. The odds ratio (OR) for the allele effect was pooled, and heterogeneity and publication bias were assessed. Twelve case-control studies met inclusion criteria and had sufficient data for extraction. There were 824 cases and 2,033 controls with a mean age range of 6.1-14.7 years. The prevalence of the minor allele in controls was 0.015 (95% confidence interval (CI): 0.008, 0.023), 0.012 (95% CI: 0.008, 0.017), and 0.105 (95% CI: 0.044, 0.167) for factor V Leiden, prothrombin II, and MTHFR, respectively. The factor V Leiden allele increased the risk of Perthes with a pooled OR of 3.10 (95% CI: 1.68, 5.72), while prothrombin II and MTHFR had non-significantly pooled OR 1.48 (95% CI: 0.71, 3.08), and 0.97 (95% CI: 0.72, 1.30), respectively. The factor V Leiden mutation is significantly related to Perthes disease, and its screening in at-risk children might be useful in the future. © 2013 Orthopaedic Research Society. Published by Wiley Periodicals, Inc.

DOI10.1002/jor.22473
CitationsScopus - 3Web of Science - 3
2014Handley TE, Kay-Lambkin FJ, Inder KJ, Attia JR, Lewin TJ, Kelly BJ, 'Feasibility of internet-delivered mental health treatments for rural populations', Social Psychiatry and Psychiatric Epidemiology, 49 275-282 (2014) [C1]

Purpose: Rural populations face numerous barriers to mental health care. Although internet-delivered mental health treatments may offer an accessible and cost-effective answer to these barriers, there has been little evaluation of the feasibility of this approach among rural communities. Methods: Data were obtained from a random rural community sample through the third wave of the Australian Rural Mental Health Study. Attitudes towards internet-delivered mental health treatments and availability of internet access were explored. Data were analysed to identify sub-groups in whom internet-delivered treatments may be usefully targeted. Results: Twelve hundred and forty-six participants completed the survey (mean age 59 years, 61 % females, 22 % from remote areas). Overall, 75 % had internet access and 20 % would consider using internet-based interventions, with 18 % meeting both of these feasibility criteria. Logistic regression revealed feasibility for internet-delivered mental health treatment was associated with younger age, male gender, being a carer, and a 12-month mental health problem. Participants who had used internet-delivered services in the past were significantly more likely to endorse these treatments as acceptable. Conclusions: There is considerable potential for internet-delivered treatments to increase service accessibility to some sub-groups, particularly among people with mental health problems who are not currently seeking help. Resistance to internet treatments appears to be largely attitudinal, suggesting that enhancing community education and familiarity with such programs may be effective in improving perceptions and ultimately access. © 2013 Springer-Verlag Berlin Heidelberg.

DOI10.1007/s00127-013-0708-9
CitationsScopus - 2Web of Science - 3
Co-authorsKerry Inder, Brian Kelly, Terry Lewin, F Kaylambkin
2014Greenop KR, Peters S, Bailey HD, Fritschi L, Attia J, Scott RJ, et al., 'Exposure to pesticides and the risk of childhood brain tumors (vol 24, pg 1269, 2013)', CANCER CAUSES & CONTROL, 25 1239-1240 (2014) [O1]
DOI10.1007/s10552-014-0418-yAuthor URL
Co-authorsRodney Scott
2014Greenop KR, Miller M, Attia J, Ashton LJ, Cohn R, Armstrong BK, Milne E, 'Maternal consumption of coffee and tea during pregnancy and risk of childhood brain tumors: results from an Australian case-control study', Cancer Causes & Control, (2014) [C1]

Purpose The causes of childhood brain tumors (CBT) are largely unknown, but gestational diet may influence this risk. The aim of this analysis was to investigate whether maternal coffee or tea consumption during pregnancy was associated with the risk of CBT. Methods The Australian Study of the Causes of Childhood Brain Tumours was a population-based, Australian case-control study conducted between 2005 and 2010. Case children were recruited from 10 pediatric oncology centers and control children by nationwide random-digit dialing, frequency matched to cases on the basis of age, sex and state of residence. Coffee and tea intake were assessed using a food frequency questionnaire. Results Data on coffee and tea consumption during pregnancy were available from 293 case mothers and 726 control mothers. Odds ratios (ORs) and confidence intervals (CIs) were calculated using multivariable unconditional logistic regression. There was little evidence of an association between gestational consumption of any coffee (OR 1.23, 95 % CI 0.92, 1.64) or tea (OR 1.00, 95 % CI 0.74, 1.36) and CBT risk. Among children aged under 5 years, the OR for any coffee consumption during pregnancy was 1.76 (95 % CI 1.09, 2.84) and for =2 cups per day during pregnancy was 2.52 (95 % CI 1.26, 5.04). There was little evidence that associations with coffee or tea intake differed by parental smoking status. Conclusions These results suggest a positive association between coffee intake =2 cups per day and risk of CBT in younger children, although some estimates are imprecise. There was no association between maternal tea drinking and risk of CBT. © 2014 Springer International Publishing Switzerland.

DOI10.1007/s10552-014-0437-8
2014Milne E, Greenop KR, Bailey HD, Fritschi L, Attia J, Scott RJ, et al., 'Childhood and parental diagnostic radiological procedures and risk of childhood brain tumors', Cancer Causes and Control, 25 375-383 (2014)
DOI10.1007/s10552-014-0338-x
CitationsScopus - 1
Co-authorsRodney Scott
2014Milne E, Greenop KR, Fritschi L, Attia J, Bailey HD, Scott RJ, et al., 'Childhood and parental diagnostic radiological procedures and risk of childhood brain tumors', Cancer Causes and Control, 25 375-383 (2014) [C1]

Purpose: Childhood brain tumors (CBT) are the second most common type of childhood cancer and the leading cause of childhood cancer mortality. Few causes of CBT are known, but parental, fetal, and early life exposures are likely to be important given the early age at diagnosis of many cases. We aimed to investigate whether parents' diagnostic radiological procedures before conception, in the mother during pregnancy or the child's procedures were associated with an increased risk of CBT. Methods: This population-based case-control study was conducted between 2005 and 2010. Cases were identified through all ten Australian pediatric oncology centers, and controls via nationwide random-digit dialing; frequency-matched to cases on age, sex and state of residence. Information on radiological exposures in the time periods of interest was obtained for 306 case and 950 control families through mailed questionnaires. Analysis used unconditional logistic regression, adjusting for matching variables and potential confounders. Results: We found no evidence of positive associations between risk of CBT overall and childhood or parental pre-pregnancy radiological procedures. Increased ORs for high-grade gliomas associated with childhood radiological procedures were based on small numbers and may be due to chance. Conclusions: Given the evidence for an increased risk of CBT in cohort studies of computed tomography (CT) in childhood, the lack of such an association in our study may be due to the reduced intensity of CTs after 2001. Future research to investigate the safety of fetal exposure to more intense procedures like CT scans is needed. © 2014 Springer International Publishing Switzerland.

DOI10.1007/s10552-014-0338-x
CitationsScopus - 1Web of Science - 1
Co-authorsRodney Scott
2014Bailey HD, Miller M, Greenop KR, Bower C, Attia J, Marshall GM, et al., 'Paternal intake of folate and vitamins B6 and B12 before conception and risk of childhood acute lymphoblastic leukemia', Cancer Causes and Control, 25 1615-1625 (2014)
DOI10.1007/s10552-014-0466-3
2014Bailey HD, Miller M, Greenop KR, Bower C, Attia J, Marshall GM, et al., 'Paternal intake of folate and vitamins B6 and B12 before conception and risk of childhood acute lymphoblastic leukemia', Cancer Causes and Control, 25 1615-1625 (2014) [C1]
DOI10.1007/s10552-014-0466-3
CitationsScopus - 1
2014White J, Dickson A, Magin P, Tapley A, Attia J, Sturm J, Carter G, 'Exploring the experience of psychological morbidity and service access in community dwelling stroke survivors: a follow-up study', DISABILITY AND REHABILITATION, 36 1600-1607 (2014) [C1]
DOI10.3109/09638288.2013.859748Author URL
CitationsWeb of Science - 2
Co-authorsGregory Carter, Parker Magin
2014White JH, Attia J, Sturm J, Carter G, Magin P, 'Predictors of depression and anxiety in community dwelling stroke survivors: A cohort study', Disability and Rehabilitation, 36 1975-1982 (2014) [C1]

Purpose: Few longitudinal studies explore post-stroke patterns of psychological morbidity and factors contributing to their change over time. We aimed to explore predictors of post-stroke depression (PSD) and post-stroke anxiety over a 12-month period. Methods: A prospective cohort study. Consecutively recruited stroke patients (n=134) participated in face-to-face interviews at baseline, 3, 6, 9, and 12 months. Primary outcome measures were depression and anxiety (measured via Hospital Anxiety and Depression Scale). Independent variables included disability (Modified Rankin Scale), Quality-of-life (Assessment Quality-of-life), social support (Multi-dimensional Scale Perceived Social Support) and community participation (Adelaide Activities Profile (AAP)). Secondary outcomes were predictors of resolution and development of PSD and anxiety. Results: Anxiety (47%) was more common than depression (22%) at baseline. Anxiety (but not depression) scores improved over time. Anxiety post-stroke was positively associated with baseline PSD (p<0.0001), baseline anxiety (p<0.0001) and less disability (p=0.042). PSD was associated with baseline anxiety (p<0.0001), baseline depression (p=0.0057), low social support (p=0.0161) and low community participation (p<0.0001). The only baseline factor predicting the resolution of PSD (if depressed at baseline) was increased social support (p=0.0421). Factors that predicted the onset of depression (if not depressed at baseline) were low community participation (p=0.0015) and higher disability (p=0.0057). Conclusion: While more common than depression immediately post-stroke, anxiety attenuates while the burden of depression persists over 12 months. Clinical programs should assess anxiety and depression, provide treatment pathways for those identified, and address modifiable risk factors, especially social support and social engagement.Implications for RehabilitationPsychological distress post stroke is persisting.Multi-disciplinary teams that establish goals with patients promoting social and community engagement could assist in managing psychological morbidity.A shift towards promoting longer-term monitoring and management of stroke survivors must be undertaken, and should consider the factors that support and hinder psychological morbidity.

DOI10.3109/09638288.2014.884172
CitationsScopus - 2
Co-authorsGregory Carter, Parker Magin
2014Moayyeri A, Hsu Y-H, Karasik D, Estrada K, Xiao S-M, Nielson C, et al., 'Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium', HUMAN MOLECULAR GENETICS, 23 3054-3068 (2014) [C1]
DOI10.1093/hmg/ddt675Author URL
CitationsScopus - 4Web of Science - 3
Co-authorsRoseanne Peel, Rodney Scott, Christopher Oldmeadow, Liz Holliday
2014Wilasrusmee C, Marjareonrungrung M, Eamkong S, Attia J, Poprom N, Jirasisrithum S, Thakkinstian A, 'Maggot therapy for chronic ulcer: A retrospective cohort and a meta-analysis', ASIAN JOURNAL OF SURGERY, 37 138-147 (2014) [C1]
DOI10.1016/j.asjsur.2013.09.005Author URL
CitationsWeb of Science - 1
2014Loth DW, Artigas MS, Gharib SA, Wain LV, Franceschini N, Koch B, et al., 'Genome-wide association analysis identifies six new loci associated with forced vital capacity', NATURE GENETICS, 46 669-677 (2014) [C1]
DOI10.1038/ng.3011Author URL
CitationsScopus - 6Web of Science - 6
Co-authorsRodney Scott, Christopher Oldmeadow, Liz Holliday
2014Wilasrusmee C, Anothaisintawee T, Poprom N, McEvoy M, Attia J, Thakkinstian A, 'Diagnostic Scores for Appendicitis: A Systematic Review of Scores¿ Performance', British Journal of Medicine and Medical Research, 4 711-730 (2014) [C1]
DOI10.9734/BJMMR/2014/5255
2014Handley TE, Hiles SA, Inder KJ, Kay-Lambkin FJ, Kelly BJ, Lewin TJ, et al., 'Predictors of Suicidal Ideation in Older People: A Decision Tree Analysis', AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY, 22 1325-1335 (2014) [C1]
DOI10.1016/j.jagp.2013.05.009Author URL
CitationsScopus - 1Web of Science - 1
Co-authorsF Kaylambkin, Brian Kelly, Kerry Inder, Terry Lewin, Roseanne Peel
2014Williams D, Conn J, Talley N, Attia J, 'Reviewing the evidence base for the peripheral sensory examination', International Journal of Clinical Practice, 68 756-760 (2014) [C1]

Background Many students find the peripheral sensory examination confusing. We set out to summarise the evidence base in order to provide guidance on the most useful manoeuvres. Methods We performed a literature review starting with 5 secondary sources, supplemented by a literature search on MEDLINE. Results A useful approach to neuropathy is to divide these into large fibre sensory neuropathy (LFSN) in which vibration and proprioception are affected, and small fibre sensory neuropathy (SFSN) in which pain and temperature are affected. Positive sensory symptoms such as burning, electric or sunburn pain point to a SFSN; negative symptoms such as loss of sensation, numbness or deep pain point to a LFSN. If LFSN is suspected, the most reproducible and best studied physical examination is a 10g monofilament, but vibration sense is also useful. There is much less data on the best physical examination for a SFSN. The most appropriate diagnostic test for SFSN is quantitative sensory testing, whereas for LFSN a nerve conduction study is indicated. Conclusions A modest amount of evidence is available to guide peripheral sensory examination but more research is needed. © 2014 John Wiley & Sons Ltd.

DOI10.1111/ijcp.12389
Co-authorsNicholas Talley
2014Williams D, Conn J, Talley N, Attia J, 'Reviewing the evidence base for the peripheral sensory examination', International Journal of Clinical Practice, 68 756-760 (2014)
DOI10.1111/ijcp.12389
Co-authorsNicholas Talley
2014Oldmeadow C, Holliday EG, McEvoy M, Scott R, Kwok JBJ, Mather K, et al., 'Concordance between direct and imputed APOE genotypes using 1000 genomes data', Journal of Alzheimer's Disease, 42 391-393 (2014) [C1]

There are a growing number of large cohorts of older persons with genome-wide genotyping data available, but APOE is not included in any of the common microarray platforms. We compared directly measured APOE genotypes with those imputed using microarray data and the '1000 Genomes' dataset in a sample of 320 Caucasians. We find 90% agreement for e2/e3/e4 genotypes and 93% agreement for predicting e4 status, yielding kappa values of 0.81 and 0.84, respectively. More stringent thresholds around allele number estimates can increase this agreement to 90-97% and kappas of 0.90-0.93.

DOI10.3233/JAD-140846
Co-authorsRodney Scott, Liz Holliday, Peter Schofield, Christopher Oldmeadow
2014Gunathilake R, Krishnamurthy V, Oldmeadow C, Kerr E, Padmakumar C, Attia J, et al., 'Relationships between age, other predictive variables, and the 90-day functional outcome after intravenous thrombolysis for acute ischemic stroke', AUSTRALASIAN JOURNAL ON AGEING, 33 19-19 (2014) [E3]
Author URL
Co-authorsChris Levi, Christopher Oldmeadow, Mark Parsons
2014Denham JW, Joseph D, Lamb DS, Spry NA, Duchesne G, Matthews J, et al., 'Short-term androgen suppression and radiotherapy versus intermediate-term androgen suppression and radiotherapy, with or without zoledronic acid, in men with locally advanced prostate cancer (TROG 03.04 RADAR): an open-label, randomised, phase 3 factorial trial', LANCET ONCOLOGY, 15 1076-1089 (2014) [C1]
DOI10.1016/S1470-2045(14)70328-6Author URL
CitationsScopus - 2Web of Science - 2
Co-authorsAllison Steigler, Christopher Oldmeadow
2014Islam MR, Attia J, Alauddin M, McEvoy M, McElduff P, Slater C, et al., 'Availability of arsenic in human milk in women and its correlation with arsenic in urine of breastfed children living in arsenic contaminated areas in Bangladesh.', Environmental Health: A Global Access Science Source, 13 1-10 (2014) [C1]
Co-authorsMilton Hasnat, Roseanne Peel, Catherine Deste, Wayne Smith
2014Ewald B, Attia J, McElduff P, 'How many steps are enough? dose-response curves for pedometer steps and multiple health markers in a community-based sample of older Australians', Journal of Physical Activity and Health, 11 509-518 (2014) [C1]

Background: Although an overall public health target of 10,000 steps per day has been advocated, the dose-response relationship for each health benefit of physical activity may differ. Methods: A representative community sample of 2458 Australian residents aged 55-85 wore a pedometer for a week in 2005-2007 and completed a health assessment. Age-standardized steps per day were compared with multiple markers of health using locally weighted regression to produce smoothed dose-response curves and then to select the steps per day matching 60% or 80% of the range in each health marker. Results: There is a linear relationship between activity level and markers of inflammation throughout the range of steps per day; this is also true for BMI in women and high density lipoprotein in men. For other markers, including waist:hip ratio, fasting glucose, depression, and SF-36 scores, the benefit of physical activity is mostly in the lower half of the distribution. Conclusions: Older adults have no plateau in the curve for some health outcomes, even beyond 12,000 steps per day. For other markers, however, there is a threshold effect, indicating that most of the benefit is achieved by 8000 steps per day, supporting this as a suitable public health target for older adults. © 2014 Human Kinetics, Inc.

DOI10.1123/jpah.2012-0091
CitationsScopus - 2Web of Science - 3
Co-authorsBen Ewald
2014McEvoy M, Schofield P, Smith W, Agho K, Mangoni AA, Soiza RL, et al., 'Memory Impairment is Associated with Serum Methylarginines in Older Adults', CURRENT ALZHEIMER RESEARCH, 11 97-106 (2014) [C1]
Author URL
CitationsScopus - 2Web of Science - 2
Co-authorsRoseanne Peel, Peter Schofield
2014Abdullah N, Attia J, Oldmeadow C, Scott RJ, Holliday EG, 'The Architecture of Risk for Type 2 Diabetes: Understanding Asia in the Context of Global Findings', INTERNATIONAL JOURNAL OF ENDOCRINOLOGY, (2014) [C1]
DOI10.1155/2014/593982Author URL
CitationsScopus - 2
Co-authorsLiz Holliday, Christopher Oldmeadow, Rodney Scott
2014Gunathilake R, Krishnamurthy V, Oldmedow C, Kerr E, Padmakumar C, Attia J, et al., 'Relationships between age, other predictive variables and the 90-day functional outcome after intravenous thrombolysis for acute ischemic stroke', INTERNATIONAL JOURNAL OF STROKE, 9 35-35 (2014)
Author URL
Co-authorsChris Levi, Christopher Oldmeadow, Mark Parsons
2014Gunathilake R, Krishnamurthy V, Oldmeadow C, Kerr E, Padmakumar C, Attia J, et al., 'Relationships between age, other predictive variables, and the 90-day functional outcome after intravenous thrombolysis for acute ischemic stroke', International Journal of Stroke, 9 E36-E37 (2014) [O1]
DOI10.1111/ijs.12347
Co-authorsMark Parsons, Christopher Oldmeadow, Chris Levi
2014Squance ML, Reeves GEM, Attia J, 'Patient Reported Frequency of Lupus Flare: Associations with Foundation Makeup and Sunscreen Use', Journal of Cosmetics, Dermatological Sciences and Applications, 4 344-354 (2014) [C1]
DOI10.4236/jcdsa.2014.45046
2014Golledge J, Clancy P, Maguire J, Lincz L, Koblar S, Mcevoy M, et al., 'Plasma angiopoietin-1 is lower after ischemic stroke and associated with major disability but not stroke incidence', Stroke, 45 1064-1068 (2014) [C1]

BACKGROUND AND PURPOSE - : Studies in rodent models suggest that upregulating angiopoietin-1 (Angpt1) improves stroke outcomes. The aims of this study were to assess the association of plasma Angpt1 with stroke occurrence and outcome. METHODS - : Plasma Angpt1 was measured in 336 patients who had experienced a recent stroke and 321 healthy controls with no stroke history. Patients with stroke (n=285) were reassessed at 3 months and plasma Angpt1 concentration on admission compared between those with severe and minor disability as assessed by the modified Rankin scale. In a separate cohort of 4032 community-acquired older men prospectively followed for a minimum of 6 years, the association of plasma Angpt1 with stroke incidence was examined. RESULTS - : Median plasma Angpt1 was 3-fold lower in patients who had experienced a recent stroke (6.42, interquartile range, 4.26-9.53 compared with 17.36; interquartile range, 14.01-22.46 ng/mL; P<0.001) and remained associated with stroke after adjustment for other risk factors. Plasma Angpt1 concentrations on admission were lower in patients who had severe disability or died at 3 months (median, 5.52; interquartile range, 3.81-8.75 ng/mL for modified Rankin scale 3-6; n=91) compared with those with minor disability (median, 7.04; interquartile range, 4.75-9.92 ng/mL for modified Rankin scale 0-2; n=194), P=0.012, and remained negatively associated with severe disability or death after adjusting for other risk factors. Plasma Angpt1 was not predictive of stroke incidence in community-dwelling older men. CONCLUSIONS - : Plasma Angpt1 concentrations are low after ischemic stroke particularly in patients with poor stroke outcomes at 3 months. Interventions effective at upregulating Angpt1 could potentially improve stroke outcomes. © 2014 American Heart Association, Inc.

DOI10.1161/STROKEAHA.113.004339
CitationsScopus - 1Web of Science - 1
Co-authorsLisa Lincz, Chris Levi, Jane Maguire
2014The Global Burden of Metabolic Risk Factors for Chronic Diseases Collaboration (BMI Mediated Effects), 'Metabolic mediators of the effects of body-mass index, overweight, and obesity on coronary heart disease and stroke: A pooled analysis of 97 prospective cohorts with 1·8 million participants', The Lancet, 383 970-983 (2014) [C1]
DOI10.1016/S0140-6736(13)61836-X
CitationsScopus - 35
Co-authorsCatherine Deste
2014Tarrant SM, Hardy BM, Byth PL, Brown TL, Attia J, Balogh ZJ, 'Preventable mortality in geriatric hip fracture inpatients', Bone and Joint Journal, 69B 1178-1184 (2014)
DOI10.1302/0301-620X.96B9.32814$2.00
CitationsScopus - 1
Co-authorsZsolt Balogh
2014Tarrant SM, Hardy BM, Byth PL, Brown TL, Attia J, Balogh ZJ, 'Preventable mortality in geriatric hip fracture inpatients', Bone and Joint Journal, 69B 1178-1184 (2014) [C1]

There is a high rate of mortality in elderly patients who sustain a fracture of the hip. We aimed to determine the rate of preventable mortality and errors during the management of these patients. A 12 month prospective study was performed on patients aged > 65 years who had sustained a fracture of the hip. This was conducted at a Level 1 Trauma Centre with no orthogeriatric service. A multidisciplinary review of the medical records by four specialists was performed to analyse errors of management and elements of preventable mortality. During 2011, there were 437 patients aged > 65 years admitted with a fracture of the hip (85 years (66 to 99)) and 20 died while in hospital (86.3 years (67 to 96)). A total of 152 errors were identified in the 80 individual reviews of the 20 deaths. A total of 99 errors (65%) were thought to have at least a moderate effect on death; 45 reviews considering death (57%) were thought to have potentially been preventable. Agreement between the panel of reviewers on the preventability of death was fair. A larger-scale assessment of preventable mortality in elderly patients who sustain a fracture of the hip is required. Multidisciplinary review panels could be considered as part of the quality assurance process in the management of these patients.

DOI10.1302/0301-620X.96B9.32814$2.00
CitationsScopus - 4Web of Science - 3
Co-authorsZsolt Balogh
2014Lai JS, Attia JR, McEvoy M, Hure AJ, 'Biochemical Validation of the Older Australian¿s Food Frequency Questionnaire Using Carotenoids and Vitamin E', Nutrients, 6 4906-4917 (2014) [C1]
DOI10.3390/nu6114906
Co-authorsAlexis Hure
2014Gupta SK, Lewis G, Rogers KM, Attia J, Rostron K, O'Neill L, et al., 'Quantitative (99m)Tc DTPA renal transplant scintigraphic parameters: assessment of interobserver agreement and correlation with graft pathologies.', American Journal of Nuclear Medicine and Molecular Imaging, 4 213-224 (2014) [C1]
Author URL
2014Dewar DC, White A, Attia J, Tarrant SM, King KL, Balogh ZJ, 'Comparison of postinjury multiple-organ failure scoring systems: Denver versus sequential organ failure assessment', Journal of Trauma and Acute Care Surgery, 77 624-629 (2014) [C1]

BACKGROUND: The Denver and Sequential Organ Failure Assessment (SOFA) scores have been used widely to describe the epidemiology of postinjury multiple-organ failure; however, differences in these scores make it difficult to compare incidence, duration, and mortality of multiple-organ failure. The study aim was to compare the performance of the Denver and SOFA scores with respect to the outcomes of mortality, intensive care unit length of stay (ICU LOS), and ventilator days.

DOI10.1097/TA.0000000000000406
Co-authorsZsolt Balogh
2014Handley TE, Hiles SA, Inder KJ, Kay-Lambkin FJ, Kelly BJ, Lewin TJ, et al., 'Predictors of suicidal ideation in older people: A decision tree analysis', American Journal of Geriatric Psychiatry, 22 1325-1335 (2014) [C1]

Objectives Suicide among older adults is a major public health issue worldwide. Although studies have identified psychological, physical, and social contributors to suicidal thoughts in older adults, few have explored the specific interactions between these factors. This article used a novel statistical approach to explore predictors of suicidal ideation in a community-based sample of older adults. Design Prospective cohort study. Participants and Setting Participants aged 55-85 years were randomly selected from the Hunter Region, a large regional center in New South Wales, Australia. Measurements Baseline psychological, physical, and social factors, including psychological distress, physical functioning, and social support, were used to predict suicidal ideation at the 5-year follow-up. Classification and regression tree modeling was used to determine specific risk profiles for participants depending on their individual well-being in each of these key areas. Results Psychological distress was the strongest predictor, with 25% of people with high distress reporting suicidal ideation. Within high psychological distress, lower physical functioning significantly increased the likelihood of suicidal ideation, with high distress and low functioning being associated with ideation in 50% of cases. A substantial subgroup reported suicidal ideation in the absence of psychological distress; dissatisfaction with social support was the most important predictor among this group. The performance of the model was high (area under the curve: 0.81). Conclusions Decision tree modeling enabled individualized "risk" profiles for suicidal ideation to be determined. Although psychological factors are important for predicting suicidal ideation, both physical and social factors significantly improved the predictive ability of the model. Assessing these factors may enhance identification of older people at risk of suicidal ideation.

DOI10.1016/j.jagp.2013.05.009
CitationsScopus - 1
Co-authorsF Kaylambkin, Roseanne Peel, Kerry Inder, Brian Kelly, Terry Lewin
2014Kodur S, Ahmad W, Heittarachi M, Reeves G, Attia J, Barker D, Collins N, 'Influence of Age on Outcome in Patients with Pulmonary Arterial Hypertension', Heart Lung and Circulation, (2014)

Background: The development of effective orally administered medical therapy for pulmonary arterial hypertension (PAH) has made a significant impact on outcome in patients with PAH. Identification of patient groups likely to derive optimal benefit is important, given cost and potential side effects; the clinical effectiveness of these therapies in older patients with PAH is unclear as the presence of co-morbidity may limit benefits of therapy. Aims: We evaluated the epidemiology of PAH in a contemporary cohort to assess the influence of age on long-term outcome using PAH-specific therapies. Results: A total of 119 patients (88% female; mean age 65±12 years) were reviewed, comprising 52% with underlying connective tissue disease. Bosentan was the PAH specific agent most frequently used. The baseline 6MWT distance in the entire cohort was 304m with age associated with a significant decline in 6MWT. Conclusions: In a large cohort of patients treated with PAH-specific therapies, patients less than 55 years of age showed improvement in 6MWT with older patients demonstrating stabilisation or decline.

DOI10.1016/j.hlc.2015.01.012
2014Handley TE, Kay-Lambkin FJ, Inder KJ, Lewin TJ, Attia JR, Fuller J, et al., 'Self-reported contacts for mental health problems by rural residents: Predicted service needs, facilitators and barriers', BMC Psychiatry, 14 (2014) [C1]

Background: Rural and remote Australians face a range of barriers to mental health care, potentially limiting the extent to which current services and support networks may provide assistance. This paper examines self-reported mental health problems and contacts during the last 12¿months, and explores cross-sectional associations between potential facilitators/barriers and professional and non-professional help-seeking, while taking into account expected associations with socio-demographic and health-related factors. Methods: During the 3-year follow-up of the Australian Rural Mental Health Study (ARMHS) a self-report survey was completed by adult rural residents (N = 1,231; 61% female 77% married; 22% remote location; mean age = 59¿years), which examined socio-demographic characteristics, current health status factors, predicted service needs, self-reported professional and non-professional contacts for mental health problems in the last 12¿months, other aspects of help-seeking, and perceived barriers. Results: Professional contacts for mental health problems were reported by 18% of the sample (including 14% reporting General Practitioner contacts), while non-professional contacts were reported by 16% (including 14% reporting discussions with family/friends). Perceived barriers to health care fell under the domains of structural (e.g., costs, distance), attitudinal (e.g., stigma concerns, confidentiality), and time commitments. Participants with 12-month mental health problems who reported their needs as met had the highest levels of service use. Hierarchical logistic regressions revealed a dose-response relationship between the level of predicted need and the likelihood of reporting professional and non-professional contacts, together with associations with socio-demographic characteristics (e.g., gender, relationships, and financial circumstances), suicidal ideation, and attitudinal factors, but not geographical remoteness. Conclusions: Rates of self-reported mental health problems were consistent with baseline findings, including higher rural contact rates with General Practitioners. Structural barriers displayed mixed associations with help-seeking, while attitudinal barriers were consistently associated with lower service contacts. Developing appropriate interventions that address perceptions of mental illness and attitudes towards help-seeking is likely to be vital in optimising treatment access and mental health outcomes in rural areas.

DOI10.1186/s12888-014-0249-0
Co-authorsTerry Lewin, F Kaylambkin, Brian Kelly, Kerry Inder, Natasha Weaver
2014Wang G, Murphy VE, Namazy J, Powell H, Schatz M, Chambers C, et al., 'The risk of maternal and placental complications in pregnant women with asthma: A systematic review and meta-analysis', Journal of Maternal-Fetal and Neonatal Medicine, 27 934-942 (2014) [C1]

Objective: To investigate if maternal asthma is associated with an increased risk of maternal and placental complications in pregnancy. Methods: Electronic databases were searched for the following terms: (asthma or wheeze) and (pregnan* or perinat* or obstet*). Cohort studies published between January 1975 and March 2012 were considered for inclusion. Forty publications met the inclusion criteria, reporting at least one maternal or placental complication in pregnant women with and without asthma. Relative risk (RR) with 95% confidence intervals (CIs) was calculated. Results: Maternal asthma was associated with a significantly increased risk of cesarean section (RR=1.31, 95%CI=[1.22-1.39]), gestational diabetes (RR=1.39, 95%CI=[1.17-1.66]), hemorrhage (antepartum: RR=1.25, 95%CI=[1.10-1.42]; postpartum: RR=1.29, 95%CI=[1.18-1.41]), placenta previa (RR=1.23, 95%CI=[1.07-1.40]), placental abruption (RR=1.29, 95%CI=[1.14-1.47]) and premature rupture of membranes (RR=1.21, 95%CI=1.07-1.37). Moderate to severe asthma significantly increased the risk of cesarean section (RR=1.19, 95%CI=[1.09-1.31]) and gestational diabetes (RR=1.19, 95%CI=[1.06-1.33]) compared to mild asthma. Bronchodilator use was associated with a significantly lowered risk of gestational diabetes (RR=0.64, 95%CI=[0.57-0.72]). Conclusions: Pregnant women with asthma are at increased risk of maternal and placental complications, and women with moderate/severe asthma may be at particular risk. Further studies are required to elucidate whether adequate control of asthma during pregnancy reduces these risks. © 2014 Informa UK Ltd. All rights reserved.

DOI10.3109/14767058.2013.847080
CitationsScopus - 5Web of Science - 4
Co-authorsVanessa Murphy, Peter Gibson
2014Napthali K, Boyle M, Tran H, Schofield PW, Peel R, McEvoy M, et al., 'Thyroid antibodies, autoimmunity and cognitive decline: is there a population-based link?', Dement Geriatr Cogn Dis Extra, 4 140-146 (2014) [C1]
DOI10.1159/000362716Author URL
Co-authorsPeter Schofield, Roseanne Peel, Christopher Oldmeadow
2014Tarrant SM, Hardy BM, Byth PL, Brown TL, Attia J, Balogh ZJ, 'Preventable mortality in geriatric hip fracture inpatients', Bone and Joint Journal, 96B 1178-1184 (2014) [C1]

There is a high rate of mortality in elderly patients who sustain a fracture of the hip. We aimed to determine the rate of preventable mortality and errors during the management of these patients. A 12 month prospective study was performed on patients aged > 65 years who had sustained a fracture of the hip. This was conducted at a Level 1 Trauma Centre with no orthogeriatric service. A multidisciplinary review of the medical records by four specialists was performed to analyse errors of management and elements of preventable mortality. During 2011, there were 437 patients aged > 65 years admitted with a fracture of the hip (85 years (66 to 99)) and 20 died while in hospital (86.3 years (67 to 96)). A total of 152 errors were identified in the 80 individual reviews of the 20 deaths. A total of 99 errors (65%) were thought to have at least a moderate effect on death; 45 reviews considering death (57%) were thought to have potentially been preventable. Agreement between the panel of reviewers on the preventability of death was fair. A larger-scale assessment of preventable mortality in elderly patients who sustain a fracture of the hip is required. Multidisciplinary review panels could be considered as part of the quality assurance process in the management of these patients.

DOI10.1302/0301-620X.96B9.32814
Co-authorsZsolt Balogh
2014Jackel D, Attia J, Pickles R, 'General medicine advanced training: lessons from the John Hunter training programme.', Intern Med J, 44 302-306 (2014) [C2]
DOI10.1111/imj.12357Author URL
2013Johnson NA, Kypri K, Saunders JB, Saitz R, Attia J, Dunlop A, et al., 'The hospital outpatient alcohol project (HOAP): protocol for an individually randomized, parallel-group superiority trial of electronic alcohol screening and brief intervention versus screening alone for unhealthy alcohol use.', Addict Sci Clin Pract, 8 14 (2013) [C3]
DOI10.1186/1940-0640-8-14Author URL
CitationsScopus - 2
Co-authorsLuke Wolfenden, Natalie Johnson, Kypros Kypri
2013Handley TE, Attia JR, Inder KJ, Kay-Lambkin FJ, Barker D, Lewin TJ, Kelly BJ, 'Longitudinal course and predictors of suicidal ideation in a rural community sample.', Australian & New Zealand Journal of Psychiatry, 47 1032-1040 (2013) [C1]
DOI10.1177/0004867413495318Author URL
CitationsScopus - 1Web of Science - 1
Co-authorsTerry Lewin, F Kaylambkin, Brian Kelly, Kerry Inder
2013Vashum KP, McEvoy M, Shi Z, Milton AH, Islam MR, Sibbritt D, et al., 'Is dietary zinc protective for type 2 diabetes? Results from the Australian longitudinal study on women's health', BMC Endocrine Disorders, 13 (2013) [C1]
DOI10.1186/1472-6823-13-40
CitationsScopus - 2Web of Science - 2
Co-authorsDeborah Loxton, Milton Hasnat, Julie Byles, Amanda Patterson
2013Walsh B, Slater S, Nair B, Attia J, 'The relationship between the apolipoprotein E e4 allele and hippocampal MRI volume in community dwelling individuals with mild Alzheimer's disease', Degenerative Neurological and Neuromuscular Disease, 3 11-14 (2013) [C1]
DOI10.2147/DNND.S40835
2013Johnson NA, Kypri K, Attia J, 'Development of an electronic alcohol screening and brief intervention program for hospital outpatients with unhealthy alcohol use.', JMIR Res Protoc, 2 e36 (2013) [C1]
DOI10.2196/resprot.2697Author URL
CitationsScopus - 1
Co-authorsNatalie Johnson, Kypros Kypri
2013Gunathilake R, Oldmeadow C, McEvoy M, Kelly B, Inder K, Schofield P, Attia J, 'Mild Hyponatremia Is Associated With Impaired Cognition And Falls In Community-Dwelling Older Persons', Journal of the American Geriatrics Society, 61 1838-1839 (2013) [C1]
DOI10.1111/jgs.12468Author URL
CitationsScopus - 7Web of Science - 7
Co-authorsBrian Kelly, Christopher Oldmeadow, Peter Schofield, Kerry Inder
2013Thakkinstian A, McKay GJ, Silvestri J, Chakravarthy U, Attia J, 'FIVE AUTHORS REPLY', AMERICAN JOURNAL OF EPIDEMIOLOGY, 177 1024-1025 (2013) [C3]
DOI10.1093/aje/kwt068Author URL
2013Debette S, Ibrahim Verbaas CA, Bressler J, Schuur M, Smith A, Bis JC, et al., 'Genome-wide Studies of Verbal Declarative Memory in Nondemented Older People: The Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium', Biological Psychiatry, (2013)

Background: Memory performance in older persons can reflect genetic influences on cognitive function and dementing processes. We aimed to identify genetic contributions to verbal declarative memory in a community setting. Methods: We conducted genome-wide association studies for paragraph or word list delayed recall in 19 cohorts from the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium, comprising 29,076 dementia- and stroke-free individuals of European descent, aged =45 years. Replication of suggestive associations (p < 5 × 10-6) was sought in 10,617 participants of European descent, 3811 African-Americans, and 1561 young adults. Results: rs4420638, near APOE, was associated with poorer delayed recall performance in discovery (p = 5.57 × 10-10) and replication cohorts (p = 5.65 × 10-8). This association was stronger for paragraph than word list delayed recall and in the oldest persons. Two associations with specific tests, in subsets of the total sample, reached genome-wide significance in combined analyses of discovery and replication (rs11074779 [HS3ST4], p = 3.11 × 10-8, and rs6813517 [SPOCK3], p = 2.58 × 10-8) near genes involved in immune response. A genetic score combining 58 independent suggestive memory risk variants was associated with increasing Alzheimer disease pathology in 725 autopsy samples. Association of memory risk loci with gene expression in 138 human hippocampus samples showed cis-associations with WDR48 and CLDN5, both related to ubiquitin metabolism. Conclusions: This largest study to date exploring the genetics of memory function in ~40,000 older individuals revealed genome-wide associations and suggested an involvement of immune and ubiquitin pathways.

DOI10.1016/j.biopsych.2014.08.027
Co-authorsChristopher Oldmeadow, Liz Holliday, Peter Schofield
2013Attia JR, Pearce R, 'The use, misuse and abuse of dabigatran', MEDICAL JOURNAL OF AUSTRALIA, 198 356-357 (2013) [C3]
DOI10.5694/mja12.10729Author URL
CitationsScopus - 6Web of Science - 5
2013Yadav S, Cotlarciuc I, Munroe PB, Khan MS, Nalls MA, Bevan S, et al., 'Genome-Wide Analysis of Blood Pressure Variability and Ischemic Stroke', Stroke, 44 2703-2709 (2013) [C1]
DOI10.1161/STROKEAHA.113.002186Author URL
CitationsScopus - 3Web of Science - 3
Co-authorsJane Maguire, Liz Holliday, Rodney Scott
2013Buitendijk GHS, Rochtchina E, Myers C, Van Duijn CM, Lee KE, Klein BEK, et al., 'Prediction of age-related macular degeneration in the general population: The three continent AMD consortium', Ophthalmology, 120 2644-2655 (2013) [C1]
DOI10.1016/j.ophtha.2013.07.053
CitationsScopus - 12Web of Science - 13
Co-authorsLiz Holliday
2013Schache M, Richardson AJ, Mitchell P, Wang JJ, Rochtchina E, Viswanathan AC, et al., 'Genetic association of refractive error and axial length with 15q14 but not 15q25 in the Blue Mountains Eye Study Cohort', Ophthalmology, 120 292-297 (2013) [C1]
CitationsScopus - 6Web of Science - 4
Co-authorsRodney Scott, Liz Holliday
2013Handley TE, Kay-Lambkin FJ, Baker AL, Lewin TJ, Kelly BJ, Inder KJ, et al., 'Incidental treatment effects of CBT on suicidal ideation and hopelessness', JOURNAL OF AFFECTIVE DISORDERS, 151 275-283 (2013) [C1]
DOI10.1016/j.jad.2013.06.005Author URL
CitationsScopus - 1Web of Science - 1
Co-authorsBrian Kelly, Kerry Inder, F Kaylambkin, Terry Lewin, Amanda Baker
2013McEvoy MA, Schofield P, Smith W, Agho K, Mangoni AA, Soiza RL, et al., 'Serum methylarginines and incident depression in a cohort of older adults', Journal of Affective Disorders, 151 493-499 (2013) [C1]
DOI10.1016/j.jad.2013.06.033Author URL
CitationsScopus - 2Web of Science - 2
Co-authorsRoseanne Peel, Kerry Inder, Peter Schofield, Brian Kelly
2013Williams FMK, Carter AM, Hysi PG, Surdulescu G, Hodgkiss D, Soranzo N, et al., 'Ischemic stroke is associated with the ABO locus: The EuroCLOT Study', Annals of Neurology, 73 16-31 (2013) [C1]
CitationsScopus - 19Web of Science - 19
Co-authorsChris Levi, Rodney Scott, Liz Holliday
2013Minelli C, De Grandi A, Weichenberger CX, Goegele M, Modenese M, Attia J, et al., 'Importance of Different Types of Prior Knowledge in Selecting Genome-Wide Findings for Follow-Up', GENETIC EPIDEMIOLOGY, 37 205-213 (2013) [C1]
DOI10.1002/gepi.21705Author URL
CitationsScopus - 4Web of Science - 2
2013Thompson JR, Goegele M, Weichenberger CX, Modenese M, Attia J, Barrett JH, et al., 'SNP Prioritization Using a Bayesian Probability of Association', GENETIC EPIDEMIOLOGY, 37 214-221 (2013) [C1]
DOI10.1002/gepi.21704Author URL
CitationsScopus - 2
2013Kongtharvonskul J, Attia J, Thamakaison S, Kijkunasathian C, Woratanarat P, Thakkinstian A, 'Clinical outcomes of double- vs single-bundle anterior cruciate ligament reconstruction: A systematic review of randomized control trials', SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS, 23 1-14 (2013) [C1]
DOI10.1111/j.1600-0838.2011.01439.xAuthor URL
CitationsScopus - 7Web of Science - 6
2013Greenop KR, Peters S, Bailey HD, Fritschi L, Attia J, Scott RJ, et al., 'Exposure to pesticides and the risk of childhood brain tumors', CANCER CAUSES & CONTROL, 24 1269-1278 (2013) [C1]
DOI10.1007/s10552-013-0205-1Author URL
CitationsScopus - 4Web of Science - 4
Co-authorsRodney Scott
2013Rattanasiri S, McDaniel DO, McEvoy M, Anothaisintawee T, Sobhonslidsuk A, Attia J, Thakkinstian A, 'The association between cytokine gene polymorphisms and graft rejection in liver transplantation: A systematic review and meta-analysis', TRANSPLANT IMMUNOLOGY, 28 62-70 (2013) [C1]
DOI10.1016/j.trim.2012.10.003Author URL
CitationsScopus - 1Web of Science - 1
2013Kottgen A, Albrecht E, Teumer A, Vitart V, Krumsiek J, Hundertmark C, et al., 'Genome-wide association analyses identify 18 new loci associated with serum urate concentrations', Nature Genetics, 45 145-154 (2013) [C1]
CitationsScopus - 66Web of Science - 67
Co-authorsChristopher Oldmeadow, Liz Holliday, Rodney Scott
2013Rietveld CA, Medland SE, Derringer J, Yang J, Esko T, Martin NW, et al., 'GWAS of 126,559 individuals identifies genetic variants associated with educational attainment', Science, 340 1467-1471 (2013) [C1]
CitationsScopus - 62Web of Science - 64
Co-authorsLiz Holliday, Christopher Oldmeadow, Rodney Scott
2013Magee CA, Holliday EG, Attia JR, Kritharides L, Banks E, 'Investigation of the relationship between sleep duration, all-cause mortality, and preexisting disease', Sleep Medicine, 14 591-596 (2013) [C1]
CitationsScopus - 6Web of Science - 5
Co-authorsLiz Holliday
2013Hunt JJ, Lumsdaine W, Attia J, Balogh ZJ, 'AO type-C distal radius fractures: the influence of computed tomography on surgeon's decision-making', ANZ JOURNAL OF SURGERY, 83 676-678 (2013) [C3]
DOI10.1111/j.1445-2197.2012.06311.xAuthor URL
CitationsScopus - 1Web of Science - 1
Co-authorsZsolt Balogh
2013Stambolian D, Wojciechowski R, Oexle K, Pirastu M, Li X, Raffel LJ, et al., 'Meta-analysis of genome-wide association studies in five cohorts reveals common variants in RBFOX1, a regulator of tissue-specific splicing, associated with refractive error', Human Molecular Genetics, 22 2754-2764 (2013) [C1]
CitationsScopus - 12Web of Science - 12
Co-authorsLiz Holliday, Rodney Scott
2013Ranasinghe WKB, Attia J, Oldmeadow C, Lawrentschuk N, Robertson J, Ranasinghe T, et al., 'Bladder carcinoma in situ (CIS) in Australia: a rising incidence for an under-reported malignancy', BJU International, 112 46-52 (2013) [C1]
DOI10.1111/bju.12052Author URL
CitationsScopus - 2Web of Science - 2
Co-authorsChristopher Oldmeadow
2013Holliday S, Magin P, Oldmeadow C, Attia J, Dunbabin J, Henry J, et al., 'An examination of the influences on New South Wales general practitioners regarding the provision of opioid substitution therapy', Drug and Alcohol Review, 32 495-503 (2013) [C1]
DOI10.1111/dar.12046Author URL
CitationsScopus - 1
Co-authorsChristopher Oldmeadow, Parker Magin
2013Allen J, Inder KJ, Lewin TJ, Attia JR, Kay-Lambkin FJ, Baker AL, et al., 'Integrating and extending cohort studies: lessons from the eXtending Treatments, Education and Networks in Depression (xTEND) study', BMC Medical Research Methodology, 13 (2013) [C1]
DOI10.1186/1471-2288-13-122Author URL
CitationsScopus - 1Web of Science - 1
Co-authorsBrian Kelly, Kerry Inder, F Kaylambkin, Amanda Baker, Terry Lewin
2013Gupta K, Dhawan A, Abel C, Talley N, Attia J, 'A re-evaluation of the scratch test for locating the liver edge', BMC GASTROENTEROLOGY, 13 (2013) [C1]
DOI10.1186/1471-230X-13-35Author URL
CitationsScopus - 1Web of Science - 1
Co-authorsNicholas Talley
2013Vejakama P, Thakkinstian A, Ingsathit A, Dhanakijcharoen P, Attia J, 'Prognostic factors of all-cause mortalities in continuous ambulatory peritoneal dialysis: a cohort study', BMC NEPHROLOGY, 14 (2013) [C1]
DOI10.1186/1471-2369-14-28Author URL
CitationsScopus - 2Web of Science - 1
2013Courtney RJ, Paul CL, Sanson-Fisher RW, Macrae FA, Carey ML, Attia J, McEvoy M, 'Individual- and provider-level factors associated with colorectal cancer screening in accordance with guideline recommendation: a community-level perspective across varying levels of risk', BMC PUBLIC HEALTH, 13 (2013) [C1]
DOI10.1186/1471-2458-13-248Author URL
CitationsScopus - 3Web of Science - 1
Co-authorsChris Paul, Mariko Carey, Rob Sanson-Fisher
2013Robertson J, McElduff P, Pearson S-A, Henry DA, Inder KJ, Attia JR, 'The health services burden of heart failure: an analysis using linked population health data-sets (vol 12, pg 103, 2012)', BMC HEALTH SERVICES RESEARCH, 13 (2013) [O1]
DOI10.1186/1472-6963-13-179Author URL
Co-authorsKerry Inder, Mddah01
2013Allen J, Inder KJ, Lewin TJ, Attia JR, Kelly BJ, 'Construct validity of the Assessment of Quality of Life - 6D (AQoL-6D) in community samples', HEALTH AND QUALITY OF LIFE OUTCOMES, 11 (2013) [C1]
DOI10.1186/1477-7525-11-61Author URL
CitationsScopus - 4Web of Science - 3
Co-authorsTerry Lewin, Kerry Inder, Brian Kelly
2013Allen J, Inder KJ, Harris ML, Lewin TJ, Attia JR, Kelly BJ, 'Quality of life impact of cardiovascular and affective conditions among older residents from urban and rural communities', HEALTH AND QUALITY OF LIFE OUTCOMES, 11 (2013) [C1]
DOI10.1186/1477-7525-11-140Author URL
CitationsScopus - 1Web of Science - 1
Co-authorsKerry Inder, Melissa Harris, Terry Lewin, Brian Kelly
2013Mangoni AA, Zinellu A, Carru C, Attia JR, McEvoy M, 'Serum thiols and cardiovascular risk scores: a combined assessment of transsulfuration pathway components and substrate/product ratios', JOURNAL OF TRANSLATIONAL MEDICINE, 11 (2013) [C1]
DOI10.1186/1479-5876-11-99Author URL
CitationsScopus - 5Web of Science - 4
2013Holliday S, Magin P, Dunbabin J, Oldmeadow C, Henry J-M, Lintzeris N, et al., 'An Evaluation of the Prescription of Opioids for Chronic Nonmalignant Pain by Australian General Practitioners', PAIN MEDICINE, 14 62-74 (2013) [C1]
DOI10.1111/j.1526-4637.2012.01527.xAuthor URL
CitationsScopus - 5Web of Science - 4
Co-authorsParker Magin, Christopher Oldmeadow
2013Numthavaj P, Tanjararak K, Roongpuvapaht B, McEvoy M, Attia J, Thakkinstian A, 'Efficacy of Mitomycin C for postoperative endoscopic sinus surgery: a systematic review and meta-analysis', CLINICAL OTOLARYNGOLOGY, 38 198-207 (2013) [C1]
DOI10.1111/coa.12114Author URL
CitationsWeb of Science - 2
2013Talseth-Palmer B, Holliday EG, Evans T-J, McEvoy MA, Attia JR, Grice DM, et al., 'Continuing difficulties in interpreting CNV data: Lessons from a genome-wide CNV association study of Australian HNPCC/lynch syndrome patients', BMC Medical Genomics, 6 1-13 (2013) [C1]
CitationsScopus - 3Web of Science - 3
Co-authorsRodney Scott, Liz Holliday, Bente Talseth-Palmer
2013Williams N, Hardy BM, Tarrant S, Enninghorst N, Attia J, Oldmeadow C, Balogh ZJ, 'Changes in hip fracture incidence, mortality and length of stay over the last decade in an Australian major trauma centre.', Archives of Osteoporosis, 8 (2013) [C1]
DOI10.1007/s11657-013-0150-3
CitationsScopus - 8
Co-authorsChristopher Oldmeadow, Zsolt Balogh
2013Holliday EG, Magee CA, Kritharides L, Banks E, Attia J, 'Short Sleep Duration Is Associated with Risk of Future Diabetes but Not Cardiovascular Disease: a Prospective Study and Meta-Analysis', PLOS ONE, 8 (2013) [C1]
DOI10.1371/journal.pone.0082305Author URL
CitationsScopus - 10Web of Science - 10
Co-authorsLiz Holliday
2013Mangoni AA, Zinellu A, Carru C, Attia JR, McEvoy M, 'Transsulfuration Pathway Thiols and Methylated Arginines: The Hunter Community Study', PLOS ONE, 8 (2013) [C1]
DOI10.1371/journal.pone.0054870Author URL
CitationsScopus - 2Web of Science - 1
2013Islam MR, Arslan I, Attia J, McEvoy M, McElduff P, Basher A, et al., 'Is Serum Zinc Level Associated with Prediabetes and Diabetes?: A Cross-Sectional Study from Bangladesh', PLOS ONE, 8 (2013) [C1]
DOI10.1371/journal.pone.0061776Author URL
CitationsScopus - 5Web of Science - 5
Co-authorsMilton Hasnat, Roseanne Peel
2013McEvoy MA, Schofield PW, Smith WT, Agho K, Mangoni AA, Soiza RL, et al., 'Serum Methylarginines and Spirometry-Measured Lung Function in Older Adults', PLOS ONE, 8 (2013) [C1]
DOI10.1371/journal.pone.0058390Author URL
Co-authorsRoseanne Peel, Wayne Smith, Peter Schofield
2013Sun C, Young TL, Mackey DA, Van Zuydam NR, Doney ASF, Palmer CNA, et al., 'Genetic loci for retinal arteriolar microcirculation', PLoS One, 8 e65804 (2013) [C1]
CitationsScopus - 2Web of Science - 2
Co-authorsRodney Scott, Liz Holliday
2013Jensen RA, Sim X, Li X, Cotch MF, Ikram MK, Holliday EG, et al., 'Genome-wide association study of retinopathy in individuals without diabetes', PLoS One, 8 e54232 (2013) [C1]
CitationsScopus - 4Web of Science - 5
Co-authorsLiz Holliday, Rodney Scott
2013Holliday EG, Smith AV, Cornes BK, Buitendijk GHS, Jensen RA, Sim X, et al., 'Insights into the genetic architecture of early stage age-related macular degeneration: A genome-wide association study meta-analysis', PLoS One, 8 e53830 (2013) [C1]
CitationsScopus - 27Web of Science - 26
Co-authorsRodney Scott, Liz Holliday
2013Sukrat B, Wilasrusmee C, Siribumrungwong B, McEvoy M, Okascharoen C, Attia J, Thakkinstian A, 'Hemoglobin Concentration and Pregnancy Outcomes: A Systematic Review and Meta-Analysis', BIOMED RESEARCH INTERNATIONAL, 1-9 (2013) [C1]
DOI10.1155/2013/769057Author URL
CitationsScopus - 1Web of Science - 1
2012Milne E, Greenop KR, Scott R, Bailey HD, Attia JR, Dalla-Pozza L, et al., 'Parental prenatal smoking and risk of childhood acute lymphoblastic leukemia', American Journal of Epidemiology, 175 43-53 (2012) [C1]
CitationsScopus - 28Web of Science - 25
Co-authorsRodney Scott
2012Gogele M, Minelli C, Thakkinstian A, Yurkiewich A, Pattaro C, Pramstaller PP, et al., 'Methods for meta-analyses of genome-wide association studies: Critical assessment of empirical evidence', American Journal of Epidemiology, 175 739-749 (2012) [C1]
CitationsScopus - 15Web of Science - 16
2012Thakkinstian A, McEvoy MA, Chakravarthy U, Chakrabarti S, McKay GJ, Ryu E, et al., 'The association between complement component 2/complement factor B polymorphisms and age-related macular degeneration: A HuGE review and meta-analysis', American Journal of Epidemiology, 176 361-372 (2012) [C1]
CitationsScopus - 22Web of Science - 21
2012Wilasrusmee C, Sukrat B, McEvoy MA, Attia JR, Thakkinstian A, 'Systematic review and meta-analysis of safety of laparoscopic versus open appendicectomy for suspected appendicitis in pregnancy', British Journal of Surgery, 99 1470-1478 (2012) [C1]
CitationsScopus - 12Web of Science - 12
2012Vejakama P, Thakkinstian A, Attia JR, 'Renoprotective effects of renin-angiotensin-aldosterone system blockers in type 2 diabetes: Demystifying multiple treatment comparisons in a network meta-analysis. Reply', Diabetologia, 55 2549-2550 (2012) [C3]
2012Vejakama P, Thakkinstian A, Lertrattananon D, Ingsathit A, Ngarmukos C, Attia JR, 'Reno-protective effects of renin-angiotensin system blockade in type 2 diabetic patients: A systematic review and network meta-analysis', Diabetologia, 55 566-578 (2012) [C1]
CitationsScopus - 29Web of Science - 28
2012Courtney RJ, Paul CL, Sanson-Fisher RW, Macrae FA, Carey ML, Attia JR, McEvoy MA, 'Colorectal cancer screening in Australia: A community-level perspective', Medical Journal of Australia, 196 516-520 (2012) [C1]
CitationsScopus - 9Web of Science - 8
Co-authorsRob Sanson-Fisher, Chris Paul, Mariko Carey
2012Murphy VE, Namazy JA, Powell H, Schatz M, Chambers C, Attia J, Gibson PG, 'A Meta-Analysis of Adverse Perinatal Outcomes in Women With Asthma EDITORIAL COMMENT', OBSTETRICAL & GYNECOLOGICAL SURVEY, 67 77-78 (2012) [C3]
DOI10.1097/OGX.0b013e318247c54dAuthor URL
Co-authorsPeter Gibson
2012Hiles SA, Baker AL, De Malmanche T, Attia JR, 'Interleukin-6, C-reactive protein and interleukin-10 after antidepressant treatment in people with depression: A meta-analysis', Psychological Medicine, 42 2015-2026 (2012) [C1]
DOI10.1017/S0033291712000128
CitationsScopus - 24Web of Science - 24
Co-authorsAmanda Baker
2012Cheng YC, Anderson CD, Bione S, Keene K, Maguire JM, Nalls M, et al., 'Are myocardial infarction-associated single-nucleotide polymorphisms associated with ischemic stroke?', Stroke, 43 980-U143 (2012) [C1]
CitationsScopus - 11Web of Science - 11
Co-authorsRodney Scott, Jane Maguire, Lisa Lincz, Pablo Moscato, Chris Levi, Liz Holliday
2012Gupta SK, Lewis G, Rogers K, Attia JR, 'Quantitative Tc-99m DTPA renal transplant scintigraphy predicts graft survival in the very early postoperative period', Nuclear Medicine Communications, 33 1292-1299 (2012) [C1]
CitationsScopus - 3Web of Science - 2
2012Suthers BG, Pickles RW, Boyle MJ, Nair BR, Cook J, Attia JR, 'The effect of context on performance of an acute medical unit: Experience from an Australian tertiary hospital', Australian Health Review, 36 320-324 (2012) [C1]
CitationsScopus - 1Web of Science - 2
2012Bailey HD, Miller M, Langridge A, De Klerk NH, Van Bockxmeer FM, Attia JR, et al., 'Maternal dietary intake of folate and vitamins B6 and B12 during pregnancy and the risk of childhood acute lymphoblastic leukemia', Nutrition and Cancer, 64 1122-1130 (2012) [C1]
DOI10.1080/01635581.2012.707278
CitationsScopus - 6Web of Science - 4
Co-authorsRodney Scott
2012Suthers B, Hansbro PM, Thambar S, McEvoy MA, Peel R, Attia JR, 'Pneumococcal vaccination may induce anti-oxidized low-density lipoprotein antibodies that have potentially protective effects against cardiovascular disease', Vaccine, 30 3983-3985 (2012) [C1]
CitationsScopus - 4Web of Science - 5
Co-authorsPhilip Hansbro, Roseanne Peel
2012Guest M, Boggess MM, Attia JR, 'Relative risk of elevated hearing threshold compared to ISO1999 normative populations for Royal Australian Air Force male personnel', Hearing Research, 285 65-76 (2012) [C1]
CitationsScopus - 1Web of Science - 1
Co-authorsMaya Guest, Catherine Deste
2012Hiles SA, Baker AL, De Malmanche T, Attia JR, 'A meta-analysis of differences in IL-6 and IL-10 between people with and without depression: Exploring the causes of heterogeneity', Brain, Behavior, and Immunity, 26 1180-1188 (2012) [C1]
CitationsScopus - 43Web of Science - 38
Co-authorsAmanda Baker
2012Woratanarat P, Angsanuntsukh C, Rattanasiri S, Attia JR, Woratanarat T, Thakkinstian A, 'Meta-analysis of pinning in supracondylar fracture of the humerus in children', Journal of Orthopaedic Trauma, 26 48-53 (2012) [C1]
CitationsScopus - 11Web of Science - 8
2012Reid MG, Parkinson L, Gibson RE, Schofield PW, D'Este CA, Attia JR, et al., 'Memory Complaint Questionnaire performed poorly as screening tool: Validation against psychometric tests and affective measures', Journal of Clinical Epidemiology, 65 199-205 (2012) [C1]
CitationsScopus - 9Web of Science - 9
Co-authorsMeredith Tavener, Catherine Deste, Julie Byles, Peter Schofield, L Parkinson
2012Handley T, Inder KJ, Kelly BJ, Attia JR, Lewin TJ, Fitzgerald MN, Kay-Lambkin FJ, 'You've got to have friends: The predictive value of social integration and support in suicidal ideation among rural communities', Social Psychiatry and Psychiatric Epidemiology, 47 1281-1290 (2012) [C1]
CitationsScopus - 9Web of Science - 9
Co-authorsTerry Lewin, F Kaylambkin, Brian Kelly, Kerry Inder
2012Magee CA, Kritharides L, Attia JR, McElduff P, Banks E, 'Short and long sleep duration are associated with prevalent cardiovascular disease in Australian adults', Journal of Sleep Research, 21 441-447 (2012) [C1]
CitationsScopus - 16Web of Science - 14
2012White JH, Gray KR, Magin PJ, Attia JR, Sturm J, Carter G, Pollack M, 'Exploring the experience of post-stroke fatigue in community dwelling stroke survivors: A prospective qualitative study', Disability and Rehabilitation, 34 1376-1384 (2012) [C1]
CitationsScopus - 9Web of Science - 8
Co-authorsParker Magin, Gregory Carter
2012White JH, Miller B, Magin PJ, Attia JR, Sturm J, Pollack M, 'Access and participation in the community: A prospective qualitative study of driving post-stroke', Disability and Rehabilitation, 34 831-838 (2012) [C1]
CitationsScopus - 11Web of Science - 9
Co-authorsParker Magin
2012Collins NJ, Hatton R, Ng K, Bhagwandeen R, Attia JR, Oldmeadow CJ, Jayasinghe R, 'Percutaneous device closure of patent foramen ovale using the premere occlusion device: Initial experience, procedural, and intermediate-term results', Journal of Invasive Cardiology, 24 164-168 (2012) [C1]
CitationsScopus - 1
Co-authorsChristopher Oldmeadow
2012Bellenguez C, Bevan S, Gschwendtner A, Spencer CCA, Burgess AI, Pirinen M, et al., 'Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke', Nature Genetics, 44 328-333 (2012) [C1]
DOI10.1038/ng.1081
CitationsScopus - 111Web of Science - 89
Co-authorsLiz Holliday, Chris Levi
2012Nyholt DR, Low S-K, Anderson CA, Painter JN, Uno S, Morris AP, et al., 'Genome-wide association meta-analysis identifies new endometriosis risk loci', Nature Genetics, 44 1355-1359 (2012) [C1]
CitationsScopus - 54Web of Science - 46
Co-authorsRodney Scott, Liz Holliday
2012Holliday EG, Maguire JM, Evans T-J, Koblar SA, Jannes J, Sturm J, et al., 'Common variants at 6p21.1 are associated with large artery atherosclerotic stroke', Nature Genetics, 44 1147-1153 (2012) [C1]
CitationsScopus - 44Web of Science - 44
Co-authorsChris Levi, Liz Holliday, Christopher Oldmeadow, Rodney Scott, Roseanne Peel, Mark Parsons, Pablo Moscato, Lisa Lincz, Jane Maguire, Wayne Smith
2012Okada Y, Sim X, Go MJ, Wu J-Y, Gu D, Takeuchi F, et al., 'Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations', Nature Genetics, 44 904-909 (2012) [C1]
CitationsScopus - 33Web of Science - 39
Co-authorsLiz Holliday, Christopher Oldmeadow, Rodney Scott
2012Siribumrungwong B, Noorit P, Wilasrusmee C, Attia JR, Thakkinstian A, 'A systematic review and meta-analysis of randomised controlled trials comparing endovenous ablation and surgical intervention in patients with varicose vein', European Journal of Vascular and Endovascular Surgery, 44 214-233 (2012) [C1]
CitationsScopus - 31Web of Science - 16
2012Lechner-Scott J, Spencer B, De Malmanche T, Attia JR, Fitzgerald M, Trojano M, et al., 'The frequency of CSF oligoclonal banding in multiple sclerosis increases with latitude', Multiple Sclerosis Journal, 18 974-982 (2012) [C1]
CitationsScopus - 16Web of Science - 13
2012Jackson N, Barlow M, Leitch J, Attia JR, 'Treating atrial fibrillation: Pulmonary vein isolation with the cryoballoon technique', Heart Lung and Circulation, 21 427-432 (2012) [C1]
CitationsScopus - 8Web of Science - 4
2012Hiew C, Duggan A, De Malmanche T, Hatton R, Baker FA, Attia JR, Collins N, 'Prevalence of Helicobacter pylori positivity in patients undergoing percutaneous coronary intervention', Internal Medicine Journal, 42 289-293 (2012) [C1]
CitationsScopus - 1Web of Science - 1
2012Courtney RJ, Paul CL, Sanson-Fisher RW, Macrae F, Attia JR, McEvoy MA, 'Current state of medical-advice-seeking behaviour for symptoms of colorectal cancer: determinants of failure and delay in medical consultation', Colorectal Disease, 14 e222-e229 (2012) [C1]
CitationsScopus - 10Web of Science - 5
Co-authorsRob Sanson-Fisher, Chris Paul
2012Thakkinstian A, Attia JR, Anothaisintawee T, Nickel JC, 'a-blockers, antibiotics and anti-inflammatories have a role in the management of chronic prostatitis/chronic pelvic pain syndrome', BJU International, 110 1014-1022 (2012) [C1]
CitationsScopus - 17Web of Science - 14
2012Murphy VE, Namazy JA, Powell H, Schatz M, Chambers C, Attia JR, Gibson PG, 'Severity of asthma in pregnancy affects perinatal outcomes - Authors' Reply', BJOG - An International Journal of Obstetrics and Gynaecology, 119 508-509 (2012) [C3]
DOI10.1111/j.1471-0528.2011.03258.x
Co-authorsPeter Gibson, Vanessa Murphy
2012Courtney RJ, Paul CL, Sanson-Fisher RW, Macrae FA, Carey ML, Attia JR, McEvoy MA, 'Colorectal cancer risk assessment and screening recommendation: A community survey of healthcare providers' practice from a patient perspective', BMC Family Practice, 13 1-9 (2012) [C1]
CitationsScopus - 2Web of Science - 2
Co-authorsRob Sanson-Fisher, Chris Paul, Mariko Carey
2012Courtney RJ, Paul CL, Sanson-Fisher RW, Macrae FA, Attia JR, McEvoy MA, 'Factors associated with consultation behaviour for primary symptoms potentially indicating colorectal cancer: A cross-sectional study on response to symptoms', BMC Gastroenterology, 12 1-9 (2012) [C1]
CitationsScopus - 6Web of Science - 5
Co-authorsRob Sanson-Fisher, Chris Paul
2012Gwynn JD, Flood VM, D'Este CA, Attia JR, Turner N, Cochrane J, et al., 'Poor food and nutrient intake among Indigenous and non-Indigenous rural Australian children', BMC Pediatrics, 12 1-14 (2012) [C1]
CitationsScopus - 7Web of Science - 6
Co-authorsJohn Wiggers, Catherine Deste, Josephine Gwynn
2012Handley T, Inder KJ, Kay-Lambkin FJ, Stain HJ, Fitzgerald M, Lewin TJ, et al., 'Contributors to suicidality in rural communities: Beyond the effects of depression', BMC Psychiatry, 12 105 (2012) [C1]
CitationsScopus - 6Web of Science - 6
Co-authorsTerry Lewin, Kerry Inder, Helen Stain, Brian Kelly, F Kaylambkin
2012Allen J, Inder KJ, Lewin TJ, Attia JR, Kelly BJ, 'Social support and age influence distress outcomes differentially across urban, regional and remote Australia: An exploratory study', BMC Public Health, 12 928 (2012) [C1]
CitationsScopus - 6Web of Science - 5
Co-authorsTerry Lewin, Brian Kelly, Kerry Inder
2012Thomas L, Rivett DA, Attia JR, Levi CR, 'Risk factors and clinical presentation of craniocervical arterial dissection: A prospective study', BMC Musculoskeletal Disorders, 13 1-6 (2012) [C3]
Co-authorsDarren Rivett, Chris Levi, Lucy Thomas
2012Robertson J, McElduff P, Pearson S-A, Henry DA, Inder KJ, Attia JR, 'The health services burden of heart failure: An analysis using linked population health data-sets', BMC Health Services Research, 12 1-11 (2012) [C1]
CitationsScopus - 9Web of Science - 11
Co-authorsKerry Inder
2012Islam MR, Khan I, Hassan SMN, McEvoy MA, D'Este CA, Attia JR, et al., 'Association between type 2 diabetes and chronic arsenic exposure in drinking water: A cross sectional study in Bangladesh', Environmental Health, 11 1-8 (2012) [C1]
CitationsScopus - 19Web of Science - 7
Co-authorsCatherine Deste, Roseanne Peel, Milton Hasnat
2012Dudding TE, Attia JR, 'Maternal factor V Leiden and adverse pregnancy outcome: Deciding whether or not to test', Journal of Maternal-Fetal & Neonatal Medicine, 25 889-894 (2012) [C1]
CitationsScopus - 3Web of Science - 1
2012White JH, Magin PJ, Attia JR, Sturm J, Carter GL, Pollack M, 'Trajectories of psychological distress after stroke', Annals of Family Medicine, 10 435-442 (2012) [C1]
CitationsScopus - 9Web of Science - 8
Co-authorsGregory Carter, Parker Magin
2012Islam MR, Khan I, Attia JR, Hassan SMN, McEvoy MA, D'Este CA, et al., 'Association between hypertension and chronic arsenic exposure in drinking water: A cross-sectional study in Bangladesh', International Journal of Environmental Research and Public Health, 9 4522-4536 (2012) [C1]
CitationsScopus - 5Web of Science - 2
Co-authorsCatherine Deste, Milton Hasnat
2011Numthavaj P, Thakkinstian A, Dejthevaporn C, Attia JR, 'Corticosteroid and antiviral therapy for Bell's palsy: A network meta-analysis', BMC Neurology, 11 1 (2011) [C1]
DOI10.1186/1471-2377-11-1
CitationsScopus - 18Web of Science - 15
2011Moxey AJ, McEvoy MA, Bowe SJ, Attia JR, 'Spirituality, religion, social support and health among older Australian adults', Australasian Journal on Ageing, 30 82-88 (2011) [C1]
DOI10.1111/j.1741-6612.2010.00453.x
CitationsScopus - 8Web of Science - 3
2011Kypri K, McCambridge J, Wilson AJ, Attia JR, Sheeran P, Bowe S, Vater T, 'Effects of study design and allocation on participant behaviour- ESDA: Study protocol for a randomized controlled trial', Trials, 12 42 (2011) [C3]
DOI10.1186/1745-6215-12-42
CitationsScopus - 17Web of Science - 17
Co-authorsKypros Kypri, Amanda Wilson
2011Thakkinstian A, McKay GJ, McEvoy MA, Chakravarthy U, Chakrabarti S, Silvestri G, et al., 'Systematic review and meta-analysis of the association between complement component 3 and age-related macular degeneration: A HuGE review and meta-analysis', American Journal of Epidemiology, 173 1365-1379 (2011) [C1]
DOI10.1093/aje/kwr025
CitationsScopus - 39Web of Science - 36
2011Reid A, Glass DC, Bailey HD, Milne E, de Klerk NH, Downie P, Fritschi L, 'Risk of childhood acute lymphoblastic leukaemia following parental occupational exposure to extremely low frequency electromagnetic fields', BRITISH JOURNAL OF CANCER, 105 1409-1413 (2011) [C1]
DOI10.1038/bjc.2011.365Author URL
CitationsScopus - 6Web of Science - 5
2011Bailey HD, Milne E, De Klerk NH, Fritschi L, Attia JR, Cole C, Armstrong BK, 'Exposure to house painting and the use of floor treatments and the risk of childhood acute lymphoblastic leukemia', International Journal of Cancer, 128 2405-2414 (2011) [C1]
DOI10.1002/ijc.25572
CitationsScopus - 10Web of Science - 9
2011Bailey HD, Armstrong BK, De Klerk NH, Fritschi L, Attia JR, Scott R, et al., 'Exposure to professional pest control treatments and the risk of childhood acute lymphoblastic leukemia', International Journal of Cancer, 129 1678-1688 (2011) [C1]
CitationsScopus - 11Web of Science - 9
Co-authorsRodney Scott
2011Ongugo K, Hall JJ, Attia JR, 'Implementing tuberculosis control in Papua New Guinea: A clash of culture and science?', Journal of Community Health, 36 423-430 (2011) [C1]
DOI10.1007/s10900-010-9324-8
CitationsScopus - 4Web of Science - 5
Co-authorsJohn Hall
2011Thakkinstian A, Attia JR, 'Treatment of chronic prostatitis/chronic pelvic pain syndrome - Reply', JAMA - Journal of the American Medical Association, 305 1298-1299 (2011) [C3]
2011Anothaisintawee T, Attia JR, Nickel JC, Thammakraisorn S, Numthavaj P, McEvoy MA, Thakkinstian A, 'Management of chronic prostatitis/ Chronic pelvic pain syndrome: A systematic review and network meta-analysis', JAMA: The Journal of the American Medical Association, 305 78-86 (2011) [C1]
DOI10.1001/jama.2010.1913
CitationsScopus - 62Web of Science - 55
2011Ngamjanyaporn P, Thakkinstian A, Verasertniyom O, Chatchaipun P, Vanichapuntu M, Nantiruj K, et al., 'Pharmacogenetics of cyclophosphamide and CYP2C19 polymorphism in Thai systemic lupus erythematosus', Rheumatology International, 31 1215-1218 (2011) [C1]
DOI10.1007/s00296-010-1420-7
CitationsScopus - 5Web of Science - 3
2011Bailey HD, De Klerk NH, Fritschi L, Attia JR, Daubenton JD, Armstrong BK, Milne E, 'Refuelling of vehicles, the use of wood burners and the risk of acute lymphoblastic leukaemia in childhood', Paediatric and Perinatal Epidemiology, 25 528-539 (2011) [C1]
CitationsScopus - 4Web of Science - 4
2011Guest M, D'Este CA, Attia JR, Boggess M, Brown A, Tavener M, et al., 'Impairment of color vision in aircraft maintenance workers', International Archives of Occupational and Environmental Health, 84 723-733 (2011) [C1]
DOI10.1007/s00420-010-0600-9
CitationsScopus - 1Web of Science - 1
Co-authorsCatherine Deste, Meredith Tavener, Maya Guest
2011Osmotherly PG, McElduff P, Attia JR, 'Factor Structure of the Neck Disability Index RESPONSE', SPINE, 36 1816-1816 (2011) [C3]
DOI10.1097/BRS.0b013e31822b4321Author URL
Co-authorsPeter Osmotherly
2011Pickering PM, Osmotherly PG, Attia JR, McElduff P, 'An examination of outcome measures for pain and dysfunction in the cervical spine: A factor analysis', Spine, 36 581-588 (2011) [C1]
DOI10.1097/brs.0b013e3181d762da
CitationsScopus - 12Web of Science - 10
Co-authorsPeter Osmotherly
2011Osmotherly PG, McElduff P, Attia JR, 'In response: Factor structure of the Neck Disability Index', Spine, 36 1816 (2011) [C3]
Co-authorsPeter Osmotherly
2011Oldmeadow CJ, Riveros RC, Holliday EG, Scott R, Moscato PA, Wang JJ, et al., 'Sifting the wheat from the chaff: Prioritizing GWAS results by identifying consistency across analytical methods', Genetic Epidemiology, 35 745-754 (2011) [C1]
DOI10.1002/gepi.20622
CitationsScopus - 5Web of Science - 5
Co-authorsLiz Holliday, Christopher Oldmeadow, Rodney Scott, Pablo Moscato
2011Milne E, Royle JA, Bennett LC, De Klerk NH, Bailey HD, Bower C, et al., 'Maternal consumption of coffee and tea during pregnancy and risk of childhood ALL: Results from an Australian case-control study', Cancer Causes & Control, 22 207-218 (2011) [C1]
DOI10.1007/s10552-010-9688-1
CitationsScopus - 7Web of Science - 5
Co-authorsRodney Scott
2011Bryant JL, Bonevski B, Paul CL, McElduff P, Attia JR, 'A systematic review and meta-analysis of the effectiveness of behavioural smoking cessation interventions in selected disadvantaged groups', Addiction, 106 1568-1585 (2011) [C1]
DOI10.1111/j.1360-0443.2011.03467.x
CitationsScopus - 24Web of Science - 24
Co-authorsBillie Bonevski, Chris Paul
2011Handley T, Inder KJ, Kelly BJ, Attia JR, Kay-Lambkin FJ, 'Urban-rural influences on suicidality: Gaps in the existing literature and recommendations for future research', Australian Journal of Rural Health, 19 279-283 (2011) [C1]
DOI10.1111/j.1440-1584.2011.01235.x
CitationsScopus - 3Web of Science - 3
Co-authorsKerry Inder, Brian Kelly, F Kaylambkin
2011Maguire JM, Thakkinstian A, Levi CR, Lincz L, Bisset L, Sturm J, et al., 'Impact of COX-2 rs5275 and rs20417 and GPIIIa rs5918 polymorphisms on 90-day ischemic stroke functional outcome: A novel finding', Journal of Stroke and Cerebrovascular Diseases, 20 134-144 (2011) [C1]
DOI10.1016/j.jstrokecerebrovasdis.2009.10.011
CitationsScopus - 21Web of Science - 20
Co-authorsLisa Lincz, Rodney Scott, Chris Levi, Jane Maguire
2011McKay GJ, Patterson CC, Chakravarthy U, Dasari S, Klaver CC, Vingerling JR, et al., 'Evidence of association of APOE with age-related macular degeneration - A pooled analysis of 15 studies', Human Mutation, 32 1407-1416 (2011) [C1]
CitationsScopus - 33Web of Science - 25
2011Khor CC, Davila S, Breunis WB, Lee YC, Shimizu C, Wright VJ, et al., 'Genome-wide association study identifies FCGR2A as a susceptibility locus for Kawasaki disease', Nature Genetics, 43 1241-1248 (2011) [C1]
CitationsScopus - 78Web of Science - 74
Co-authorsRodney Scott, Liz Holliday
2011Guest M, Boggess MM, D'Este CA, Attia JR, Brown A, 'An observed relationship between vestibular function and auditory thresholds in aircraft-maintenance workers', Journal of Occupational and Environmental Medicine, 53 146-152 (2011) [C1]
DOI10.1097/jom.0b013e318204fa7f
CitationsScopus - 2Web of Science - 2
Co-authorsMaya Guest, Catherine Deste
2011Guest M, Attia JR, D'Este CA, Boggess MM, Brown AM, Gibson RE, et al., 'Peripheral neuropathy in military aircraft maintenance workers in Australia', Journal of Occupational and Environmental Medicine, 53 381-387 (2011) [C1]
DOI10.1097/jom.0b013e318212226d
Co-authorsMaya Guest, Meredith Tavener, Catherine Deste
2011Thomas L, Rivett DA, Attia JR, Parsons MW, Levi CR, 'Risk factors and clinical features of craniocervical arterial dissection', Manual Therapy, 16 351-356 (2011) [C1]
DOI10.1016/j.math.2010.12.008
CitationsScopus - 18Web of Science - 14
Co-authorsLucy Thomas, Chris Levi, Darren Rivett, Mark Parsons
2011Jones LJ, Craven P, Attia JR, Thakkinstian A, Wright IM, 'Network meta-analysis of indomethacin versus ibuprofen versus placebo for PDA in preterm infants', Archives of Disease in Childhood-Fetal and Neonatal Edition, 96 F45-F52 (2011) [C1]
DOI10.1136/adc.2009.168682
CitationsScopus - 28Web of Science - 25
Co-authorsIan Wright
2011McGettigan P, Lincz L, Attia JR, McElduff P, Bissett L, Peel R, et al., 'The risk of coronary thrombosis with cyclo-oxygenase-2 inhibitors does not vary with polymorphisms in two regions of the cyclo-oxygenase-2 gene', British Journal of Clinical Pharmacology, 72 707-714 (2011) [C1]
DOI10.1111/j.1365-2125.2011.03957.x
CitationsScopus - 6Web of Science - 6
Co-authorsBarrie Stokes, Roseanne Peel, Lisa Lincz, Mddah01
2011Gwynn JD, Flood VM, D'Este CA, Attia JR, Turner N, Cochrane J, Wiggers JH, 'The reliability and validity of a short FFQ among Australian Aboriginal and Torres Strait Islander and non-Indigenous rural children', Public Health Nutrition, 14 388-401 (2011) [C1]
DOI10.1017/s1368980010001928
CitationsScopus - 11Web of Science - 9
Co-authorsCatherine Deste, John Wiggers, Josephine Gwynn
2011Nair BR, Heim C, Krishnan C, D'Este CA, Marley J, Attia JR, 'The effect of Baroque music on behavioural disturbances in patients with dementia', Australasian Journal on Ageing, 30 11-15 (2011) [C1]
DOI10.1111/j.1741-6612.2010.00439.x
CitationsScopus - 7Web of Science - 2
Co-authorsCatherine Deste
2011Ranasinghe WKB, Wright TA, Attia JR, McElduff P, Doyle T, Bartholomew M, et al., 'Effects of bariatric surgery on urinary and sexual function', BJU International, 107 88-94 (2011) [C1]
DOI10.1111/j.1464-410x.2010.09509.x
CitationsScopus - 10Web of Science - 8
2011Thompson JR, Attia JR, Minelli C, 'The meta-analysis of genome-wide association studies', Briefings in Bioinformatics, 12 259-269 (2011) [C1]
DOI10.1093/bib/bbr020
CitationsScopus - 19Web of Science - 17
2011Murphy VE, Namazy JA, Powell H, Schatz M, Chambers C, Attia JR, Gibson PG, 'A meta-analysis of adverse perinatal outcomes in women with asthma', BJOG: An International Journal of Obstetrics and Gynaecology, 118 1314-1323 (2011) [C1]
DOI10.1111/j.1471-0528.2011.03055.x
CitationsScopus - 66Web of Science - 56
Co-authorsPeter Gibson, Vanessa Murphy
2010Lees KR, Bluhmki E, Von Kummer R, Brott TG, Toni D, Grotta JC, et al., 'Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials', The Lancet, 375 1695-1703 (2010) [C1]
DOI10.1016/S0140-6736(10)60491-6
CitationsScopus - 718Web of Science - 644
Co-authorsChris Levi, Mark Parsons
2010Tran HA, Reeves GEM, Lyons TJ, Attia JR, 'Histopathologic findings of autoimmunity in thyroid, pituitary, and adrenal diseases in chronic Hepatitis C postmortem cases', Endocrine Practice, 16 566-569 (2010) [C1]
DOI10.4158/EP09359.OR
2010Attia JR, Thakkinstian A, McElduff P, Milne E, Dawson S, Scott R, et al., 'Detecting genotyping error using measures of degree of Hardy-Weinberg disequilibrium', Statistical Applications in Genetics and Molecular Biology, 9 17 (2010) [C1]
DOI10.2202/1544-6115.1463
CitationsScopus - 10Web of Science - 5
Co-authorsRodney Scott
2010Janssen H, Bernhardt J, Collier JM, Sena ES, McElduff P, Attia JR, et al., 'An enriched environment improves sensorimotor function post-ischemic stroke', Neurorehabilitation and Neural Repair, 24 802-813 (2010) [C1]
DOI10.1177/1545968310372092
CitationsScopus - 36Web of Science - 29
Co-authorsNeil Spratt
2010Ikram MK, Xueling S, Jensen RA, Cotch MF, Hewitt AW, Ikram MA, et al., 'Four Novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation In Vivo', Plos Genetics, 6 1-12 (2010) [C1]
DOI10.1371/journal.pgen.1001184
CitationsScopus - 54Web of Science - 50
Co-authorsRodney Scott, Liz Holliday
2010Proietto AM, Otton GR, Symonds IM, McEvoy MA, Attia JR, Gilbert M, et al., 'Polymorphisms in genes of the steroid hormone biosynthesis and metabolism pathways and endometrial cancer risk', Cancer Epidemiology, 34 328-337 (2010) [C1]
DOI10.1016/j.canep.2010.03.005
CitationsScopus - 25Web of Science - 25
Co-authorsIan Symonds, Katie Ashton, Rodney Scott
2010Wang JJ, Attia JR, 'Study Designs in Epidemiology and Levels of Evidence', American Journal of Ophthalmology, 149 367-370 (2010) [C2]
CitationsScopus - 3Web of Science - 2
2010Holliday EG, Scott R, Attia JR, 'Evidence-based medicine in the era of biomarkers: Teaching a new dog old tricks?', Clinical Pharmacology and Therapeutics, 88 740-742 (2010) [C2]
DOI10.1038/clpt.2010.214
CitationsScopus - 4Web of Science - 2
Co-authorsRodney Scott, Liz Holliday
2010Smith DR, Attia JR, McEvoy MA, 'Exploring new frontiers in occupational epidemiology: The Hunter Community Study (HCS) from Australia', Industrial Health, 48 244-248 (2010) [C1]
DOI10.2486/indhealth.48.244
CitationsScopus - 5Web of Science - 5
Co-authorsDerek Smith
2010Milne E, Royle JA, Miller M, Bower C, De Klerk NH, Bailey HD, et al., 'Maternal folate and other vitamin supplementation during pregnancy and risk of acute lymphoblastic leukemia in the offspring', International Journal of Cancer, 126 2690-2699 (2010) [C1]
DOI10.1002/ijc.24969
CitationsScopus - 32Web of Science - 27
Co-authorsRodney Scott
2010Schofield PW, Lee SJ, Lewin TJ, Lyall G, Moyle J, Attia JR, McEvoy MA, 'The Audio Recorded Cognitive Screen (ARCS): A flexible hybrid cognitive test instrument', Journal of Neurology Neurosurgery and Psychiatry, 81 602-607 (2010) [C1]
DOI10.1136/jnnp.2009.188003
CitationsScopus - 12Web of Science - 10
Co-authorsTerry Lewin, Peter Schofield
2010Kamanamool N, McEvoy MA, Attia JR, Ingsathit A, Ngamjanyaporn P, Thakkinstian A, 'Efficacy and adverse events of mycophenolate mofetil versus cyclophosphamide for induction therapy of lupus nephritis: Systematic review and meta-analysis', Medicine, 89 227-235 (2010) [C1]
DOI10.1097/MD.0b013e3181e93d00
CitationsScopus - 34Web of Science - 25
2010Lemmens R, Buysschaert I, Geelen V, Fernandez-Cadenas I, Montaner J, Schmidt H, et al., 'The Association of the 4q25 susceptibility variant for atrial fibrillation with stroke is limited to stroke of cardioembolic etiology', Stroke, 41 1850-1857 (2010) [C1]
DOI10.1161/STROKEAHA.110.587980
CitationsScopus - 27Web of Science - 25
Co-authorsJane Maguire, Chris Levi
2010Limsuwan T, Thakkinstian A, Verasertniyom O, Vanichapuntu M, Attia JR, Janwityanujit S, Nantiruj K, 'Possible protective effects of the Glu27 allele of beta(2)-Adrenergic receptor polymorphism in Thai asthmatic patients', Asian Pacific Journal of Allergy and Immunology, 28 107-114 (2010) [C1]
CitationsScopus - 3Web of Science - 2
2010Bailey HD, Milne E, De Klerk N, Fritschi L, Bower C, Attia JR, Armstrong BK, 'Representativeness of child controls recruited by random digit dialling', Paediatric and Perinatal Epidemiology, 24 293-302 (2010) [C1]
DOI10.1111/j.1365-3016.2010.01099.x
CitationsScopus - 26Web of Science - 26
2010Guest M, Boggess M, Attia JR, D'Este CA, Brown A, Gibson RE, et al., 'Hearing impairment in F-111 maintenance workers: The study of health outcomes in aircraft maintenance personnel (SHOAMP) general health and medical study', American Journal of Industrial Medicine, 53 1159-1169 (2010) [C1]
DOI10.1002/ajim.20867
CitationsScopus - 9Web of Science - 8
Co-authorsCatherine Deste, Meredith Tavener, Maya Guest
2010McEvoy MA, Smith WT, D'Este CA, Duke JM, Peel R, Schofield PW, et al., 'Cohort Profile: The Hunter Community Study', International Journal of Epidemiology, 39 1452-1463 (2010) [C1]
DOI10.1093/ije/dyp343
CitationsScopus - 52Web of Science - 51
Co-authorsCatherine Deste, Wayne Smith, Derek Smith, Peter Schofield, Mddah01, Rodney Scott, Roseanne Peel, Julie Byles, Ben Ewald
2010Ewald BD, McEvoy MA, Attia JR, 'Pedometer counts superior to physical activity scale for identifying health markers in older adults', British Journal of Sports Medicine, 44 756-761 (2010) [C1]
DOI10.1136/bjsm.2008.048827
CitationsScopus - 11Web of Science - 9
Co-authorsBen Ewald
2010Wood LG, Attia JR, McElduff P, McEvoy MA, Gibson PG, 'Assessment of dietary fat intake and innate immune activation as risk factors for impaired lung function', European Journal of Clinical Nutrition, 64 818-825 (2010) [C1]
DOI10.1038/ejcn.2010.68
CitationsScopus - 5Web of Science - 5
Co-authorsLisa Wood, Peter Gibson
2010Marsden DL, Spratt NJ, Walker R, Barker DJ, Attia JR, Pollack MR, et al., 'Trends in stroke attack rates and case fatality in the Hunter Region, Australia 1996-2008', Cerebrovascular Diseases, 30 500-507 (2010) [C1]
DOI10.1159/000319022
CitationsScopus - 16Web of Science - 16
Co-authorsChris Levi, Neil Spratt, Mark Parsons
2010Hiew C, Williams T, Hatton R, Narasimhan S, O'Connor S, Baker F, et al., 'Influence of age on long-term outcome after emergent percutaneous coronary intervention for ST-elevation myocardial infarction', Journal of Invasive Cardiology, 22 273-277 (2010) [C1]
CitationsScopus - 3Web of Science - 2
2010Bailey HD, Armstrong BK, De Klerk NH, Fritschi L, Attia JR, Lockwood L, et al., 'Exposure to Diagnostic Radiological Procedures and the Risk of Childhood Acute Lymphoblastic Leukemia', Cancer Epidemiology Biomarkers & Prevention, 19 2897-2909 (2010) [C1]
DOI10.1158/1055-9965.EPI-10-0542
CitationsScopus - 9Web of Science - 5
2010Gwynn JD, Hardy LL, Wiggers JH, Smith WT, D'Este CA, Turner N, et al., 'The validation of a self-report measure and physical activity of Australian Aboriginal and Torres Strait Islander and non-Indigenous rural children', Australian and New Zealand Journal of Public Health, 34 S57-S65 (2010) [C1]
DOI10.1111/j.1753-6405.2010.00555.x
CitationsScopus - 9Web of Science - 6
Co-authorsWayne Smith, Catherine Deste, Josephine Gwynn, John Wiggers
2010Arj-Ong S, Thakkinstian A, McEvoy MA, Attia JR, 'A systematic review and meta-analysis of tumor necrosis factor alpha-308 polymorphism and Kawasaki disease', Pediatrics International, 52 527-532 (2010) [C1]
DOI10.1111/j.1442-200X.2010.03105.x
CitationsScopus - 11Web of Science - 10
2010Gupta SK, McGrath S, Rogers K, Attia JR, Lewis G, Viswanathan S, et al., 'Fixed dose (555 MBq; 15 mCi) radioiodine for the treatment of hyperthyroidism: outcome and its predictors', Internal Medicine Journal, 40 854-857 (2010) [C1]
DOI10.1111/j.1445-5994.2010.02348.x
CitationsScopus - 8Web of Science - 5
2010Ashton KA, Proietto AM, Otton GR, Symonds IM, McEvoy MA, Attia JR, Scott R, 'Toll-Like Receptor (TLR) and Nucleosome-binding Oligomerization Domain (NOD) gene polymorphisms and endometrial cancer risk', BMC Cancer, 10 1-7 (2010) [C1]
DOI10.1186/1471-2407-10-382
CitationsScopus - 21Web of Science - 21
Co-authorsKatie Ashton, Ian Symonds, Rodney Scott
2010Loten C, Attia JR, Hullick C, Marley J, McElduff P, 'Point of care troponin decreases time in the emergency department for patients with possible acute coronary syndrome: A randomised controlled trial', Emergency Medicine Journal, 27 194-198 (2010) [C1]
DOI10.1136/emj.2008.069427
CitationsScopus - 11Web of Science - 8
2009Ashton KA, Proietto AM, Otton GR, Symonds IM, McEvoy MA, Attia JR, et al., 'Estrogen receptor polymorphisms and the risk of endometrial cancer', BJOG: An International Journal of Obstetrics and Gynaecology, 116 1053-1061 (2009) [C1]
DOI10.1111/j.1471-0528.2009.02185.x
CitationsScopus - 27Web of Science - 25
Co-authorsKatie Ashton, Rodney Scott, Ian Symonds
2009Loten C, Attia JR, Hullick C, Marley J, McElduff P, 'Validation of a point of care troponin assay in real life emergency department conditions', Emergency Medicine Australasia, 21 286-292 (2009) [C1]
DOI10.1111/j.1742-6723.2009.01198.x
CitationsScopus - 5Web of Science - 3
2009Loten C, Isbister GK, Jamcotchian MA, Hullick C, McElduff P, Attia JR, Marley J, 'Adverse outcomes following emergency department discharge of patients with possible acute coronary syndrome', Emergency Medicine Australasia, 21 455-464 (2009) [C1]
DOI10.1111/j.1742-6723.2009.01229.x
CitationsScopus - 5Web of Science - 5
Co-authorsGeoff Isbister
2009Brown A, Gibson RE, Tavener MA, Guest M, D'Este CA, Byles JE, et al., 'Sexual function in F-111 maintenance workers: The study of health outcomes in aircraft maintenance personnel', Journal of Sexual Medicine, 6 1569-1578 (2009) [C1]
DOI10.1111/j.1743-6109.2009.01237.x
CitationsScopus - 3Web of Science - 3
Co-authorsMaya Guest, Meredith Tavener, Catherine Deste, Julie Byles
2009Milne E, Royle JA, De Klerk NH, Blair E, Bailey H, Cole C, et al., 'Fetal growth and risk of childhood acute lymphoblastic leukemia: Results from an Australian case-control study', American Journal of Epidemiology, 170 221-228 (2009) [C1]
DOI10.1093/aje/kwp117
CitationsScopus - 28Web of Science - 27
Co-authorsRodney Scott
2009Minelli C, Thompson JR, Abrams KR, Thakkinstian A, Attia JR, 'The quality of meta-analyses of Genetic Association Studies: A veview with recommendations', American Journal of Epidemiology, 170 1333-1343 (2009) [C1]
DOI10.1093/aje/kwp350
CitationsScopus - 23Web of Science - 22
2009Miles S, Rogers KM, Thomas P, Soans B, Attia JR, Abel C, et al., 'A comparison of single-photon emission CT lung scintigraphy and CT pulmonary angiography for the diagnosis of pulmonary embolism', Chest, 136 1546-1553 (2009) [C1]
DOI10.1378/chest.09-0361
CitationsScopus - 33Web of Science - 28
Co-authorsCatherine Deste, Michael Hensley
2009McCambridge J, Kypri K, Attia JR, Elbourne D, 'Re: Promoting regular mammography screening I: A systematic assessment of validity in a randomized trial', Journal of the National Cancer Institute, 101 1029-1030 (2009) [C3]
DOI10.1093/jnci/djp154
CitationsScopus - 2Web of Science - 2
Co-authorsKypros Kypri
2009Parsons MW, Miteff F, Bateman GA, Spratt NJ, Loiselle A, Attia JR, Levi CR, 'Acute ischemic stroke imaging-guided tenecteplase treatment in an extended time window', Neurology, 72 915-921 (2009) [C1]
DOI10.1212/01.wnl.0000344168.05315.9d
CitationsScopus - 62Web of Science - 48
Co-authorsMark Parsons, Neil Spratt, Chris Levi
2009Hallinan R, Crettol S, Agho K, Attia JR, Besson J, Croquette-Krokar M, et al., 'Cannabis and benzodiazepines as determinants of methadone trough plasma concentration variability in maintenance treatment: A transnational study', European Journal of Clinical Pharmacology, 65 1113-1120 (2009) [C1]
DOI10.1007/s00228-009-0706-8
CitationsScopus - 11Web of Science - 9
2009Ashton KA, Proietto AM, Otton GR, Symonds IM, McEvoy MA, Attia JR, et al., 'Polymorphisms in TP53 and MDM2 combined are associated with high grade endometrial cancer', Gynecologic Oncology, 113 109-114 (2009) [C1]
DOI10.1016/j.ygyno.2008.12.036
CitationsScopus - 26Web of Science - 26
Co-authorsRodney Scott, Katie Ashton, Ian Symonds
2009Attia JR, Ioannidis JPA, Thakkinstian A, McEvoy MA, Scott R, Minelli C, et al., 'How to use an article about genetic association A: Background concepts', JAMA: Journal of the American Medical Association, 301 74-81 (2009) [C1]
DOI10.1001/jama.2008.901
CitationsScopus - 58Web of Science - 55
Co-authorsRodney Scott
2009Attia JR, Ioannidis JPA, Thakkinstian A, McEvoy MA, Scott R, Minelli C, et al., 'How to use an article about genetic association B: Are the results of the study valid?', JAMA: Journal of the American Medical Association, 301 191-197 (2009) [C1]
DOI10.1001/jama.2008.946
CitationsScopus - 85Web of Science - 84
Co-authorsRodney Scott
2009Attia JR, Ioannidis JPA, Thakkinstian A, McEvoy MA, Scott R, Minelli C, et al., 'How to use an article about genetic association C: What are the results and will they help me in caring for my patients?', JAMA: Journal of the American Medical Association, 301 304-308 (2009) [C1]
DOI10.1001/jama.2008.993
CitationsScopus - 41Web of Science - 37
Co-authorsRodney Scott
2009Hallinan R, Byrne A, Agho K, McMahon CG, Tynan P, Attia JR, 'Hypogonadism in men receiving methadone and buprenorphine maintenance treatment', International Journal of Andrology, 32 131-139 (2009) [C1]
DOI10.1111/j.1365-2605.2007.00824.x
CitationsScopus - 31Web of Science - 20
2009Thakkinstian A, Thompson JR, Minelli C, Attia JR, 'Choosing between per-genotype, per-allele, and trend approaches for initial detection of gene-disease association', Journal of Applied Statistics, 36 633-646 (2009) [C1]
DOI10.1080/02664760802484990
CitationsScopus - 15Web of Science - 13
2009Anothaisintawee T, Rattanasiri S, Ingsathit A, Attia JR, Thakkinstian A, 'Prevalence of chronic kidney disease: A systematic review and meta-analysis', Clinical Nephrology, 71 244-254 (2009) [C1]
CitationsScopus - 12Web of Science - 11
2009Lowe J, Mensch M, McElduff P, Fitzgerald M, Attia JR, 'Does an advanced insulin education programme improve outcomes and health service use for people with Type 2 diabetes? A 5-year follow-up of the Newcastle Empowerment course', Diabetic Medicine, 26 1277-1281 (2009) [C1]
DOI10.1111/j.1464-5491.2009.02858.x
CitationsScopus - 2Web of Science - 1
2009Narasimhan S, McKay K, Attia JR, 'Staff perspectives of a cardiac short stay unit', Australian Journal of Advanced Nursing, 26 23-28 (2009) [C1]
CitationsScopus - 1Web of Science - 1
2009Tran HA, Reeves GE, Gibson R, Attia JR, 'Development of thyroid diseases in the treatment of chronic hepatitis C with alpha-interferon may be a good prognosticator in achieving a sustained virological response: A meta-analysis', Journal of Gastroenterology and Hepatology, 24 1163-1168 (2009) [C1]
DOI10.1111/j.1440-1746.2009.05874.x
CitationsScopus - 13Web of Science - 12
2009MacDonald K, Lowe J, Barker DJ, Mensch M, Attia JR, 'Effect of popular takeaway foods on blood glucose levels in type 1 diabetes mellitus patients on intensive insulin therapy', International Journal of Clinical Practice, 63 189-194 (2009) [C1]
DOI10.1111/j.1742-1241.2008.01970.x
CitationsScopus - 5Web of Science - 5
2009Xu L, Dibley M, D'Este CA, Phillips M, Porteous JE, Attia JR, 'Food groups and risk of forearm fractures in postmenopausal women in Chengdu, China', Climacteric, 12 222-229 (2009) [C1]
DOI10.1080/13697130802626958
CitationsScopus - 7Web of Science - 7
Co-authorsCatherine Deste
2009Ewald BD, Duke JM, Thakkinstian A, Attia JR, Smith WT, 'Physical activity of older Australians measured by pedometry', Australasian Journal on Ageing, 28 127-133 (2009) [C1]
DOI10.1111/j.1741-6612.2009.00372.x
CitationsScopus - 14Web of Science - 11
Co-authorsWayne Smith, Ben Ewald
2008Osmotherly PG, Attia JR, Thakkinstian A, 'Can clinical measures of upper quarter postural muscle performance predict neck pain in visual display terminal operators?', Journal of Back and Musculoskeletal Rehabilitation, 21 113-120 (2008) [C1]
Co-authorsPeter Osmotherly
2008Ewald BD, Ewald D, Thakkinstian A, Attia JR, 'Meta-analysis of B type natriuretic peptide and N-terminal pro B natriuretic peptide in the diagnosis of clinical heart failure and population screening for left ventricular systolic dysfunction', Internal Medicine Journal, 38 101-113 (2008) [C1]
DOI10.1111/j.1445-5994.2007.01454.x
CitationsScopus - 48Web of Science - 41
Co-authorsBen Ewald
2008Ashton KA, Proietto AM, Otton GR, Symonds IM, McEvoy MA, Attia JR, et al., 'The influence of the Cyclin D1 870 G>A polymorphism as an endometrial cancer risk factor', BMC Cancer, 8 1-6 (2008) [C1]
DOI10.1186/1471-2407-8-272
CitationsScopus - 7Web of Science - 6
Co-authorsIan Symonds, Katie Ashton, Rodney Scott
2008Davis SM, Donnan GA, Parsons MW, Levi CR, Butcher KS, Peeters A, et al., 'Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): A placebo-controlled randomised trial', The Lancet Neurology, 7 299-309 (2008) [C1]
DOI10.1016/s1474-4422(08)70044-9
CitationsScopus - 527Web of Science - 469
Co-authorsChris Levi, Mark Parsons
2008Dudding TE, Heron J, Thakkinstian A, Nurk E, Golding J, Pembrey M, et al., 'Factor V Leiden is associated with pre-eclampsia but not with fetal growth restriction: A genetic association study and meta-analysis', Journal of Thrombosis and Haemostasis, 6 1868-1875 (2008) [C1]
DOI10.111/j.1538-7836.2008.03134.x
CitationsScopus - 31Web of Science - 5
Co-authorsRodney Scott
2008Hallinan R, Byrne A, Agho K, McMahon C, Tynan P, Attia JR, 'Erectile dysfunction in men receiving methadone and buprenorphine maintenance treatment', Journal of Sexual Medicine, 5 684-692 (2008) [C1]
DOI10.1111/j.1743-6109.2007.00702.x
CitationsScopus - 52Web of Science - 45
2008Ryan RL, King BR, Anderson DG, Attia JR, Collins CE, Smart CE, 'Influence of and optimal insulin therapy for a low-glycemic index meal in children with type 1 diabetes receiving intensive insulin therapy', Diabetes Care, 31 1485-1490 (2008) [C1]
DOI10.2337/dc08-0331
CitationsScopus - 11Web of Science - 7
Co-authorsBruce King, Clare Collins
2008White JH, Magin PJ, Attia JR, Pollack MR, Sturm J, Levi CR, 'Exploring poststroke mood changes in community-dwelling stroke survivors: A qualitative study', Archives of Physical Medicine and Rehabilitation, 89 1701-1707 (2008) [C1]
DOI10.1016/j.apmr.2007.12.048
CitationsScopus - 12Web of Science - 9
Co-authorsParker Magin, Chris Levi
2008Quain DA, Parsons MW, Loudfoot AR, Spratt NJ, Evans MK, Russell ML, et al., 'Improving access to acute stroke therapies: A controlled trial of organised pre-hospital and emergency care', Medical Journal of Australia, 189 429-433 (2008) [C1]
CitationsScopus - 59Web of Science - 50
Co-authorsNeil Spratt, Mark Parsons, Chris Levi
2008Thompson JR, Minelli C, Abrams KR, Thakkinstian A, Attia JR, 'Combining information from related meta-analyses of genetic association studies', Journal of the Royal Statistical Society: Applied Statistics, 57 103-115 (2008) [C1]
DOI10.1111/j.1467-9876.2007.00603.x
CitationsScopus - 3Web of Science - 3
2008Maguire JM, Thakkinstian A, Sturm J, Levi CR, Lincz L, Parsons MW, et al., 'Polymorphisms in platelet glycoprotein 1b [alpha] and factor VII and risk of ischemic stroke', Stroke, 39 1710-1716 (2008) [C1]
DOI10.1161/strokeaha.107.507228
CitationsScopus - 24Web of Science - 23
Co-authorsChris Levi, Mark Parsons, Jane Maguire, Lisa Lincz
2008Lowe J, Linjawi S, Mensch M, James K, Attia JR, 'Flexible eating and flexible insulin dosing in patients with diabetes: Results of an intensive self-management course', Diabetes Research and Clinical Practice, 80 439-443 (2008) [C1]
DOI10.1016/j.diabres.2008.02.003
CitationsScopus - 35Web of Science - 29
2008D'Este CA, Attia JR, Brown AM, Gibson RE, Gibberd RW, Tavener MA, et al., 'Cancer incidence and mortality in aircraft maintenance workers', American Journal of Industrial Medicine, 51 16-23 (2008) [C1]
DOI10.1002/ajim.20540
CitationsScopus - 5Web of Science - 5
Co-authorsRobert Gibberd, Meredith Tavener, Catherine Deste, Maya Guest
2008Minelli C, Thompson JR, Abrams KR, Thakkinstian A, Attia JR, 'How should we use information about HWE in the meta-analyses of genetic association studies', International Journal of Epidemiology, 37 136-146 (2008) [C1]
DOI10.1093/ije/dym234
CitationsScopus - 60Web of Science - 57
2008Shi Z, McEvoy MA, Luu J, Attia JR, 'Dietary fat and sleep duration in Chinese men and women', International Journal of Obesity, 32 1835-1840 (2008) [C1]
DOI10.1038/ijo.2008.191
CitationsScopus - 24Web of Science - 23
2008Thakkinstian A, Tran HA, Reeves GE, Murch S, Attia JR, 'A clinical decision rule to aid ordering of serum and urine protein electrophoresis for case-finding of paraproteins in hospitalized inpatients', Journal of General Internal Medicine, 23 1688-1692 (2008) [C1]
DOI10.1007/s11606-008-0712-z
2008Thakkinstian A, Dmitrienko S, Gerbase-Delima M, McDaniel DO, Inigo P, Chow KM, et al., 'Association between cytokine gene polymorphisms and outcomes in renal transplantation: A meta-analysis of individual patient data', Nephrology Dialysis Transplantation, 23 3017-3023 (2008) [C1]
DOI10.1093/ndt/gfn185
CitationsScopus - 29Web of Science - 29
2008Osmotherly PG, Attia JR, 'The interplay of static and dynamic postural factors in neck pain', Hong Kong Physiotherapy Journal, 26 9-17 (2008) [C1]
DOI10.1016/S1013-7025(09)70003-X
CitationsScopus - 2
Co-authorsPeter Osmotherly
2007Tran HA, Attia JR, Jones TL, Batey RG, 'Pegylated interferon-alpha 2 beta in combination with ribavirin does not aggravate thyroid dysfunction in comparison to regular interferon-alpha 2 beta in a hepatitis C population: Meta-analysis', Journal of Gastroenterology and Hepatology, 22 472-476 (2007) [C1]
DOI10.1111/j.1440-1746.2006.04771.x
CitationsScopus - 20Web of Science - 19
2007Attia JR, Thakkinstian A, Wang Y, Lincz L, Parsons MW, Sturm J, et al., 'The PAI-1 4G/5G gene polymorphism and ischemic stroke: An association study and meta-analysis', Journal of Stroke and Cerebrovascular Diseases, 16 173-179 (2007) [C1]
DOI10.1016/j.jstrokecerebrovasdis.2007.03.002
CitationsScopus - 31
Co-authorsChris Levi, Rodney Scott, Lisa Lincz, Mark Parsons
2007Bailey H, Henley N, Robertson L, Armstrong B, Attia JR, Milne E, 'Applying Persuasion Principles Did Not Increase Questionnaire Response: A Randomised Controlled Trial of a Fridge Magnet Gift', Australasian Epidemiologist, 14 6-10 (2007) [C1]
2007White JH, Alston MK, Marquez JL, Sweetapple AL, Pollack MR, Attia JR, et al., 'Community-Dwelling Stroke Survivors: Function Is Not the Whole Story With Quality of Life', Archives of Physical Medicine and Rehabilitation, 88 1140-1146 (2007) [C1]
DOI10.1016/j.apmr.2007.06.003
CitationsScopus - 21Web of Science - 21
Co-authorsJodie Marquez, Chris Levi
2007Honoki K, Stojanovski E, McEvoy MA, Fujii H, Tsujiuchi T, Kido A, et al., 'Prognostic significance of p16(INK4a) alteration for Ewing sarcoma - A meta-analysis', Cancer, 110 1351-1360 (2007) [C1]
DOI10.1002/cncr.22908
CitationsScopus - 16Web of Science - 16
Co-authorsElizabeth Stojanovski
2007Duke JM, McEvoy MA, Sibbritt DW, Guest M, Smith WT, Attia JR, 'Vibrotactile threshold measurement for detecting peripheral neuropathy: Defining variability and a normal range for clinical and research use', Diabetologia, 50 2305-2312 (2007) [C1]
DOI10.1007/s00125-007-0813-y
CitationsScopus - 17Web of Science - 16
Co-authorsMaya Guest, Wayne Smith
2007Wark PA, Bucchieri F, Johnston SL, Gibson PG, Hamilton L, Mimica J, et al., 'IFN-gamma-induced protein 10 is a novel biomarker of rhinovirus-induced asthma exacerbations', Journal of Allergy and Clinical Immunology, 120 586-593 (2007) [C1]
DOI10.1016/j.jaci.2007.04.046
CitationsScopus - 82Web of Science - 78
Co-authorsPeter Wark, Joanna Latter, Peter Gibson
2006Jm S, Ms S, Gj H, Attia JR, Thakkinstian A, Yi Q, et al., 'Association between phosphodiesterase 4D gene and ischaemic stroke', Journal of Neurology, Neurosurgery and Psychiatry Online, 77 1067-1069 (2006) [C1]
DOI10.1136/jnnp.2006.092106
CitationsScopus - 49Web of Science - 45
2006Schofield PW, Gibson RE, Tavener MA, Attia JR, D'Este CA, Guest M, et al., 'Neuropsychological health in F-111 aircraft maintenance workers', NeuroToxicology, 27 852-860 (2006) [C1]
DOI10.1016/j.neuro.2006.02.002
CitationsScopus - 11Web of Science - 11
Co-authorsMeredith Tavener, Catherine Deste, Maya Guest, Peter Schofield
2006Khoshdel A, Thakkinstian A, Carney SL, Attia JR, 'Estimation of an age-specific reference interval for pulse wave velocity: a meta-analysis', Journal of Hypertension, 24 1231-1237 (2006) [C1]
DOI10.1097/01.hjh.0000234098.85497.31
CitationsScopus - 37Web of Science - 29
2006Hallinan R, Ray J, Byrne A, Agho KE, Attia JR, 'Therapeutic thresholds in methadone maintenance treatment: A receiver operating characteristic analysis', Drug and Alcohol Dependence, 81 129-136 (2006) [C1]
DOI10.1016/j.drugalcdep.2005.06.005
CitationsScopus - 12Web of Science - 12
2006Attia JR, Page JH, 'A graphic framework for teaching critical appraisal of randomised controlled trials', Equine Veterinary Journal, 38 7-9 (2006) [C1]
DOI10.2746/042516406775374199
CitationsScopus - 1Web of Science - 1
2006Thakkinstian A, Han PY, McEvoy MA, Smith WT, Hoh J, Magnusson K, et al., 'Systematic review and meta-analysis of the association between complementary factor HY402H polymorphisms and age-related macular degeneration', Human Molecular Genetics, 15 2784-2790 (2006) [C1]
DOI10.1093/hmg/ddl220
CitationsScopus - 142Web of Science - 130
Co-authorsWayne Smith
2006Khoshdel A, Attia JR, Carney SL, 'Basic concepts in meta-analysis: a primer for clinicians', International Journal of Clinical Practice, 60 1287-1294 (2006) [C1]
DOI10.1111/j.1742-1241.2006.01078.x
CitationsScopus - 20Web of Science - 17
2006Zhang X, Attia JR, D'Este CA, Ma X-Y, 'The relationship between higher blood pressure and ischaemic, haemorrhagic stroke among Chinese and Caucasians: meta-analysis', European Journal of Cardiovascular Prevention and Rehabilitation, 13 429-437 (2006) [C1]
DOI10.1097/01.hjr.0000214607.99113.b8
CitationsScopus - 22Web of Science - 16
Co-authorsCatherine Deste
2006Osmotherly PG, Attia JR, 'The healthy worker survivor effect in a study of neck muscle performance measures in call-centre operators', Work, 26 399-406 (2006) [C1]
CitationsScopus - 4
Co-authorsPeter Osmotherly
2006Xu L, Phillips M, D'Este CA, Dibley MJ, Porteous JE, Attia JR, 'Diet, activity, and other lifestyle risk factors for forearm fracture in postmenopausal women in China: a case-control study', Menopause - The Journal of the North American Menopause Society, 13 102-110 (2006) [C1]
DOI10.1097/01.gme.0000191206.20738.da
CitationsScopus - 3Web of Science - 4
Co-authorsCatherine Deste
2006Attia JR, D'Este CA, Schofield PW, Brown AM, Gibson RE, Tavener MA, et al., 'Mental health in F-111 maintenance workers: the study of Health Outcomes in Aircraft Maintenance Personnel (SHOAMP) general health and medical study', Journal of Occupational and Environmental Medicine, 48 682-691 (2006) [C1]
DOI10.1097/01.jom.0000205985.00559.84
CitationsScopus - 11Web of Science - 10
Co-authorsPeter Schofield, Meredith Tavener, Catherine Deste
2006Thakkinstian A, Bowe SJ, McEvoy MA, Smith WT, Attia JR, 'Association between apolipoprotein E polymorphisms and age-related macular degeneration: A HuGE review and meta-analysis', American Journal of Epidemiology, 164 813-822 (2006) [C1]
DOI10.1093/aje/kwj279
CitationsScopus - 50Web of Science - 45
Co-authorsWayne Smith
2005Thakkinstian A, McEvoy MA, Minelli C, Gibson PG, Hancox B, Duffy D, et al., 'Systematic review and meta-analysis of the association between beta(2)-adrenoceptor polymorphisms and asthma: A HuGE review', American Journal of Epidemiology, 162 201-211 (2005) [C1]
DOI10.1093/aje/kwi184
CitationsScopus - 223Web of Science - 221
Co-authorsPeter Gibson
2005Minelli C, Thompson JR, Abrams KR, Thakkinstian A, Attia JR, 'The choice of a genetic model in the meta-analysis of molecular association studies', International Journal of Epidemiology, 34 1319-1328 (2005) [C1]
DOI10.1093/ije/dyi169
CitationsScopus - 89Web of Science - 85
2005Attia J, Schofield P, 'What now for Alzheimer's disease? An epidemiological evaluation of the AD2000 trial', Australian Prescriber, 28 134-135 (2005)
CitationsScopus - 1
Co-authorsPeter Schofield
2005Lindqvist PG, Merlo J, Dudding T, Attia J, 'Rebuttal: Meta-analysis of the relationship of factor V Leiden and intrauterine growth restriction-based on solid evidence? (multiple letters) [6]', Thrombosis and Haemostasis, 94 230-232 (2005)
2005Zhang X, Attia JR, D'Este CA, Yu XH, Wu XG, 'A risk score predicted coronary heart disease and stroke in a Chinese cohort', Journal of Clinical Epidemiology, 58 951-958 (2005) [C1]
DOI10.1016/j.jclinepi.2005.01.013
CitationsScopus - 27Web of Science - 19
Co-authorsCatherine Deste
2005Settakorn J, Rangdaeng S, Arpornchayanon O, Lekawanvijit S, Bhoopat L, Attia JR, 'Why were limbs amputated? An evaluation of 216 surgical specimens from Chiang Mai University', Archives of Orthopaedic and Trauma Surgery, 125 701-705 (2005) [C1]
DOI10.1007/s00402-005-0060-y
CitationsScopus - 8Web of Science - 4
2005Thakkinstian A, McElduff P, D'Este CA, Duffy D, Attia JR, 'A method for meta-analysis of molecular association studies', Statistics in Medicine, 24 1291-1306 (2005) [C1]
DOI10.1002/sim.2010
CitationsScopus - 290Web of Science - 294
Co-authorsCatherine Deste
2005Chiarelli PE, Bower W, Wilson AJ, Attia JR, Sibbritt DW, 'Estimating the prevalence of urinary and faecal incontinence in Australia: systematic review', Australasian Journal on Ageing, 24 19-27 (2005) [C1]
DOI10.1111/j.1741-6612.2005.00063.x
CitationsScopus - 9Web of Science - 7
Co-authorsAmanda Wilson, Pauline Chiarelli
2004Xu L, McElduff P, D'Este CA, Attia JR, 'Does dietary calcium have a protective effect on bone fractures in women? A meta-analysis of observational studies', The British Journal of Nutrition, 91 625-634 (2004) [C1]
DOI10.1079/BJN20031085
CitationsScopus - 21Web of Science - 17
Co-authorsCatherine Deste
2004Attia JR, Nair BR, Mears SR, Hitchcock K, 'Patient-oxygen dissociation curves: surveying the spectrum of oxygen-delivery methods', MJA, 181 677-678 (2004) [C1]
CitationsScopus - 4Web of Science - 3
2004Attia JR, Nair BR, Sibbritt DW, Ewald BD, Paget NS, Wellard RF, et al., 'Generating pre-test probabilities: a neglected area in clinical decision making', Medical Journal of Australia, 180 449-454 (2004) [C1]
CitationsScopus - 27Web of Science - 17
Co-authorsBen Ewald
2004Zhang X, Attia JR, D'Este CA, Yu X, 'Prevalence and Magnitude of Classical Risk Factors for Stroke in a Cohort of 5092 Chinese Steelworkers Over 13.5 Years of Follow-up', Stroke, 35 1052-1056 (2004) [C1]
DOI10.1161/01.STR.0000125305.12859.ff
CitationsScopus - 33Web of Science - 25
Co-authorsCatherine Deste
2004Rodsutti J, Hensley M, Thakkinstian A, D'Este C, Attia J, 'A clinical decision rule to prioritize polysomnography in patients with suspected sleep apnea', SLEEP, 27 694-699 (2004) [C1]
Author URL
CitationsScopus - 16Web of Science - 16
Co-authorsCatherine Deste
2004Kelly H, Attia JR, Andrews R, Heller RF, 'The number needed to vaccinate (NNV) and population extensions of the NNV: comparison of influenza and pneumococcal vaccine programmes for people aged 65 years and over', Vaccine, 22 2192-2198 (2004) [C1]
DOI10.1016/j.vaccine.2003.11.052
CitationsScopus - 37Web of Science - 32
2004Ewald BD, Attia JR, 'Which test to detect microalbuminuria in diabetic patients?', Australian Family Physician, 33 565-568 (2004) [C1]
CitationsScopus - 14
Co-authorsBen Ewald
2004Attia JR, Dudding TE, Infante-Rivard C, 'Addendum to: The association between adverse pregnancy outcomes and maternal factor V Leiden genotype: A meta-analysis', Thrombosis and Haemostasis, 92 434 (2004) [C3]
CitationsScopus - 2
2004Thakkinstian A, D'Este CA, Eisman J, Nguyen T, Attia JR, 'Meta-Analysis of Molecular Association Studies: Vitamin D Receptor Gene Polymorphisms and BMD as a Case Study', Journal of Bone & Mineral Research, 19 419 (2004) [C1]
DOI10.1359/JBMR.0301265
CitationsScopus - 141Web of Science - 115
Co-authorsCatherine Deste
2004Thakkinstian A, D'Este CA, Attia JR, 'Haplotype analysis of VDR gene polymorphisms: a meta-analysis', Osteoporosis International: with other metabolic bone diseases, 15 729-734 (2004) [C1]
DOI10.1007/s00198-004-1601-x
CitationsScopus - 48Web of Science - 38
Co-authorsCatherine Deste
2004Attia JR, D'Este CA, Levi CR, 'The progress trial three years later. HOPE trial may shed some light', BMJ, 329 1403-1404 (2004) [C1]
DOI10.1136/bmj.329.7479.1403-d
Co-authorsCatherine Deste, Chris Levi
2004Attia J, Eikelboom JW, Chunilal SD, Ginsberg JS, Mehra MR, 'Review: Clinical gestalt strategies and clinical prediction rules have similar discriminate pretest probabilities of pulmonary embolism', Evidence-Based Medicine, 9 155-155 (2004)
DOI10.1136/ebm.9.5.155
2004Dudding TE, Attia JR, 'The association between adverse pregnancy outcomes and maternal factor V Leiden genotype: a meta-analysis', Journal of Thrombosis and Haemostasis, 91 700-711 (2004) [C2]
CitationsScopus - 95Web of Science - 76
2004Scott R, Crooks R, Rose L, Attia JR, Thakkinstian A, Thomas L, et al., 'Germline Missense Changes in the APC Gene and Their Relationship to Disease', Hereditary Cancer in Clinical Practice, 2 81-91 (2004) [C1]
DOI10.1186/1897-4287-2-2-81
Co-authorsRodney Scott
2004Xf Z, Attia JR, D'Este CA, Yu X, Wu X, 'Prevalence and magnitude of classical risk factors for coronary heart disease in a cohort of 4400 Chinese steelworkers over 13.5 years' follow-up', European Journal of Cardiovascular Prevention & Rehabilitation, 11 113-120 (2004) [C1]
DOI10.1097/01.hjr.0000125480.31039.37
CitationsScopus - 16Web of Science - 15
Co-authorsCatherine Deste
2004Attia JR, 'Statistics with common sense', Australian Prescriber, 27 66-66 (2004)
2003Page J, Attia JR, 'Using Bayes nomogram to help interpret odds ratios', EBM Online Evidence-based Medicine, 8 132-134 (2003) [C2]
CitationsScopus - 5
2003Chiarelli PE, Bower W, Wilson AJ, Sibbritt DW, Attia JR, 'The prevalence of urinary incontinence in the community: a systematic review', Commonwealth Department of Health and Aged Care, (2003) [C3]
Co-authorsAmanda Wilson, Pauline Chiarelli
2003Chiarelli PE, Bower W, Wilson AJ, Sibbritt DW, Attia JR, 'The prevalence of faecal incontinence: a systematic review', Commonwealth Department of Health and Aged Care, (2003) [C3]
Co-authorsPauline Chiarelli, Amanda Wilson
2003Nair BR, Attia JR, Bowe SJ, Mears SR, Hitchcock K, 'Interns are from Venus, consultants are from Mars: differential perception among clinicians', Medical Journal of Australia, 179 659-661 (2003) [C1]
2003Wang Y, Levi CR, Attia JR, D'Este CA, Spratt N, Fisher JD, 'Seasonal Variation in Stroke in the Hunter Region, Australia: A 5-Year Hospital-Based Study, 1995-2000', Stroke: a journal of cerebral circulation, 34 1144-1150 (2003) [C1]
DOI10.1161/01.STR.0000067703.71251.B6
CitationsScopus - 58Web of Science - 54
Co-authorsChris Levi, Neil Spratt, Catherine Deste
2003Chunilal S, Eikelboom JW, Attia JR, Miniati M, Panju A, Simel DL, Ginsberg JS, 'Does this Patient Have Pulmonary Embolism?', JAMA, 290 2849-2858 (2003) [C1]
DOI10.1001/jama.290.21.2849
CitationsScopus - 110Web of Science - 86
2003Edwards MJ, Agho KE, Attia JR, Diaz P, Hayes T, Illingworth A, Roddick LG, 'Case-Control Study of Cleft Lip or Palate After Maternal Use of Topical Corticosteroids During Pregnancy', American Journal of Medical Genetics, 120 459-463 (2003) [C1]
DOI10.1002/ajmg.a.20130
CitationsScopus - 42Web of Science - 36
2003Attia J, 'Moving beyond sensitivity and specificity: Using likelihood ratios to help interpret diagnostic tests', Australian Prescriber, 26 111-113 (2003)

Properties of diagnostic tests have traditionally been described using sensitivity, specificity, and positive and negative predictive values. These measures, however, reflect population characteristics and do not easily translate to individual patients. Likelihood ratios are a more practical way of making sense of diagnostic test results and have immediate clinical relevance. In general a useful test provides a high positive likelihood ratio and a small negative likelihood ratio.

CitationsScopus - 59
2003Attia JR, Thakkinstian A, D'Este CA, 'Meta-analyses of molecular association studies: Methodologic lessons for genetic epidemiology', The Journal of Clinical Epidemiology, 297-303 (2003) [C1]
DOI10.1016/S0895-4356(03)00011-8
CitationsScopus - 206Web of Science - 197
Co-authorsCatherine Deste
2003Attia J, Nair K, Price JM, Jacobs A, 'On abandoning ties and avoiding nose rings [7]', British Medical Journal, 327 345-345 (2003)
CitationsScopus - 1
2003Wang Y, Levi CR, D'Este CA, Attia JR, Fisher JD, 'Variation of Stroke Attack Rates in Rural, Urban, and Coalfields Areas of the Hunter Region, Australia 1995-2000', Journal of Stroke & Cerebrovascular Diseases, 12 103-110 (2003) [C1]
DOI10.1053/jscd.2003.12
CitationsScopus - 3
Co-authorsCatherine Deste, Chris Levi
2002Nair BR, Attia JR, Mears S, Hitchcock K, 'Evidence-based physicians' dressing: a crossover trial', Medical Journal of Australia, 177(2) 681-682 (2002) [C1]
CitationsScopus - 16Web of Science - 14
2002Attia JR, Page J, Heller R, Dobson A, 'Impact numbers in health policy decisions', Journal of Epidemiology & Community Health, 56 600-605 (2002) [C1]
CitationsScopus - 15Web of Science - 9
2002Heller R, Dobson A, Attia JR, Page J, 'Impact numbers: measures of risk factor impact on the whole population from case-control and cohort studies', Journal of Epidemiology & Community Health, 56 606-610 (2002) [C1]
CitationsScopus - 23Web of Science - 16
2002McElduff P, Attia JR, Ewald BD, Cockburn JD, Heller R, 'Estimating the contribution of individual risk factors to disease in a person with more than one risk factor', The Journal of Clinical Epidemiology, 55 588-592 (2002) [C1]
CitationsScopus - 15Web of Science - 12
Co-authorsBen Ewald
2001Attia JR, Ray J, Cook D, Douketis J, Ginsberg J, Geerts W, 'Deep vein thrombosis and its prevention in critically ill adults', Archives of Internal medicine, 161 1268-1279 (2001) [C1]
CitationsScopus - 192Web of Science - 150
2001Edmond K, Attia JR, D'Este CA, Condon J, 'Drowning and near-drowning in Northern Territory children', Medical Journal of Australia, 175 605-608 (2001) [C1]
CitationsScopus - 9Web of Science - 6
Co-authorsCatherine Deste
2001Attia J, Page J, 'A graphic framework for teaching critical appraisal of randomised controlled trials', Evidence-Based Medicine, 6 68-69 (2001)

Students of evidence-based medicine often try unsuccessfully to commit to memory a particular critical appraisal framework (often lengthy), or they have to depend on pocket cards and are lost without them. We have described a pedagogic aid: a flow diagram of an RCT, which has been developed over years of teaching residents. This diagram focuses on the steps in an RCT, and by drawing arrows, it highlights the biases possible at each step. This diagram serves as a framework on which the list of critical appraisal questions can be hung and is easy to remember.

DOI10.1136/ebm.6.3.68
CitationsScopus - 2
2001Attia JR, Page J, 'Editorial: A graphic framework for teaching critical appraisal of randomzied controlled trials', Internal Medicine Journal, 134 A11-A12 (2001) [C2]
2000Cook D, Attia JR, Weaver B, McDonald E, Meade M, Crowther M, 'Venous Thromboembolic Disease: An Observational Study in Medical-Surgical Intensive Care Unit Patients', Journal of Critical Care, 15 127-132 (2000) [C1]
CitationsScopus - 65Web of Science - 49
2000Attia J, Margetts P, Guyatt G, 'Review: Sensitive thyrotropin testing in unselected inpatients has low diagnostic accuracy. Commentary', Evidence-Based Medicine, 5 29-29 (2000)
DOI10.1136/ebm.5.1.29
CitationsScopus - 1
2000Attia J, Hatala R, Cook DJ, Wong JG, 'Review: The physical examination can exclude the diagnosis of meningitis in low-risk adults. Commentary', Evidence-Based Medicine, 5 28-28 (2000)
DOI10.1136/ebm.5.1.28
CitationsScopus - 1
1999Attia J, Margetts P, Guyatt G, 'Diagnosis of thyroid disease in hospitalized patients - A systematic review', ARCHIVES OF INTERNAL MEDICINE, 159 658-665 (1999)
DOI10.1001/archinte.159.7.658Author URL
CitationsScopus - 58Web of Science - 41
1999Attia J, Hatala R, Cook DJ, Wong JG, 'Does this adult patient have acute meningitis?', JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 282 175-181 (1999)
DOI10.1001/jama.282.2.175Author URL
CitationsScopus - 125Web of Science - 92
1999Douketis JD, Feightner JW, Attia J, Feldman WF, 'Periodic health examination, 1999 update: 1. Detection, prevention and treatment of obesity', CANADIAN MEDICAL ASSOCIATION JOURNAL, 160 513-525 (1999)
Author URL
CitationsScopus - 132Web of Science - 102
1998Attia J, Cook DJ, 'Prognosis in anoxic and traumatic coma', CRITICAL CARE CLINICS, 14 497-+ (1998)
DOI10.1016/S0749-0704(05)70013-0Author URL
CitationsWeb of Science - 32
1998Attia JR, Cook D, 'Indicators of poor neurologic prognosis in patients comatose due to intracranial bleeds and trauma: a systematic review and critical appraisal of the evidence.', Clinical Intensive Care, 9 129-133 (1998)
1996Attia JR, Cook D, 'Indicators of poor neurological prognosis in patients with anoxic coma: a systematic review and critical appraisal of the evidence.', Clinical Intensive Care, 7 244-247 (1996)
1995Attia J, Gupta S, Dunn RJ, 'Expression and secretion of a soluble form of myelin-associated glycoprotein (MAG).', Methods in molecular biology (Clifton, N.J.), 39 363-384 (1995)
1993ATTIA J, HICKS L, OIKAWA K, KAY CM, DUNN RJ, 'STRUCTURAL-PROPERTIES OF THE MYELIN-ASSOCIATED GLYCOPROTEIN ECTODOMAIN', JOURNAL OF NEUROCHEMISTRY, 61 718-726 (1993)
Author URL
CitationsScopus - 7Web of Science - 8
1989ATTIA J, TROPAK M, JOHNSON PW, NEWERLYABRANOW W, PAWSON T, RODER JC, DUNN RJ, 'MODULATED ADHESION - A PROPOSAL FOR THE ROLE OF MYELIN-ASSOCIATED GLYCOPROTEIN IN MYELIN WRAPPING', CLINICAL CHEMISTRY, 35 717-720 (1989)
Author URL
CitationsWeb of Science - 11
1989JOHNSON PW, ATTIA J, RICHARDSON CD, RODER JC, DUNN RJ, 'SYNTHESIS OF SOLUBLE MYELIN-ASSOCIATED GLYCOPROTEIN IN INSECT AND MAMMALIAN-CELLS', GENE, 77 287-296 (1989)
DOI10.1016/0378-1119(89)90076-0Author URL
CitationsWeb of Science - 12
1987Fitt PS, Sharma N, Attia J, Korecky B, 'Studies of adenosine incorporation in Langendorff rat heart and rat heart mitochondria', Molecular and Cellular Biochemistry: an international journal for chemical biology in health and disease, 78 37-46 (1987)
Show 373 more journal articles

Review (1 outputs)

YearCitationAltmetricsLink
2004Attia JR, 'Statistics with common sense', Australian Prescriber (2004) [D2]

Conference (71 outputs)

YearCitationAltmetricsLink
2015Sarwar G, Attia J, Bisquera A, 'NEUTRAL EFFECT OF INHALED CORTICOSTEROIDS ON BONE MINERAL DENSITY', RESPIROLOGY (2015)
Author URL
2014Mather KA, Thalamuthu A, Oldmeadow C, Song F, Armstrong NJ, Poljak A, et al., 'Genome-wide significant results identified for plasma apolipoprotein h levels', Alzheimer's & Dementia (2014) [E3]
DOI10.1016/j.jalz.2014.05.1526
Co-authorsRodney Scott, Peter Schofield, Liz Holliday, Christopher Oldmeadow
2014Chouraki VA, Jakobsdottir J, Mather K, Adams H, Mollon J, Oldmeadow C, et al., 'A genome-wide meta-analysis of plasma clusterin levels in the charge consortium', Alzheimer's & Dementia, Washington, DC (2014) [E3]
DOI10.1016/j.jalz.2014.05.1159
Co-authorsRodney Scott, Liz Holliday, Christopher Oldmeadow
2014Bolton KA, Holliday EG, McEvoy M, Attia J, Proietto A, Otton G, et al., 'A HIGHLY POLYMORPHIC AG REPEAT IN THE UPSTREAM REGULATORY REGION OF THE ESTROGEN-INDUCED GENE EIG121 IS A POTENTIAL MODIFIER OF ENDOMETRIAL CANCER RISK', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY (2014) [E3]
Author URL
Co-authorsRodney Scott, Kelly Kiejda, Liz Holliday, Nikola Bowden
2014Gunathilake R, Krishnamurthy V, Oldmedow C, Kerr E, Padmakumar C, Attia J, et al., 'Relationships between age, other predictive variables and the 90-day functional outcome after intravenous thrombolysis for acute ischemic stroke', INTERNATIONAL JOURNAL OF STROKE (2014) [E3]
Author URL
Co-authorsChristopher Oldmeadow, Mark Parsons, Chris Levi
2014Kerr E, Sanson-Fisher RW, Paul CL, DEste C, Parsons M, Bladin C, et al., 'Thrombolysis ImPlementation in Stroke (TIPS): Evaluating the effectiveness of a strategy to increase the adoption of best evidence practice: An overview of data collected during the baseline period', INTERNATIONAL JOURNAL OF STROKE (2014) [E3]
Author URL
Co-authorsCatherine Deste, Chris Paul, Rob Sanson-Fisher, Frans Henskens, Chris Levi, Mark Parsons
2014Bidarian-Moniri A, Nilsson M, Attia J, Ejnell H, 'Prone positioning for treatment of obstructive sleep apnoea', JOURNAL OF SLEEP RESEARCH, Tallinn, ESTONIA (2014) [E3]
Author URL
2014Bolton KA, Holliday EG, McEvoy M, Attia J, Proietto A, Otton G, et al., 'A highly polymorphic AG repeat in the upstream regulatory region of the estrogen gene EIG121 is a potential modifier of endometrial cancer risk.', Asia-Pacific Journal of Clinical Oncology, Newcastle, NSW, Australia (2014) [E3]
DOI10.1111/ajco.12335
Co-authorsNikola Bowden, Kelly Kiejda, Rodney Scott, Liz Holliday
2014Lai J, Hure A, McEvoy M, Byles J, Attia J, 'Diet Quality And Depressive Symptoms In Mid-age Australian Women: Results From Preliminary Analysis', International Society for Affective Disorders Oral Abstract Book, Berlin, Germany (2014) [E3]
Co-authorsJulie Byles, Alexis Hure
2013Lai JS, Hiles S, Hure AJ, McEvoy M, Attia J, 'SYSTEMATIC REVIEW AND META-ANALYSIS OF DIETARY PATTERNS AND DEPRESSION: OBSERVATIONAL STUDIES', ANNALS OF NUTRITION AND METABOLISM (2013) [E3]
Author URL
Co-authorsAlexis Hure
2013Collins N, Kodur S, Ahmad W, Barker D, Davies A, Attia J, 'Influence of Age on Outcome in Treatment of Pulmonary Arterial Hypertension', Heart, Lung and Circulation, Gold Coast (2013) [E3]
DOI10.1016/j.hlc.2013.05.190Author URL
2013Thomas J, Parsons O, Traylor M, Li L, Bevan S, Sudlow C, et al., 'The impact of CCS and TOAST classification systems on genetic associations with ischaemic stroke', INTERNATIONAL JOURNAL OF STROKE (2013) [E3]
Author URL
Co-authorsLiz Holliday, Chris Levi
2013Dickson A, White J, Magin P, Attia J, Sturm J, Carter G, et al., 'Exploring the experience of psychological morbidity and service access in community dwelling stroke survivors: A qualitative follow up study', INTERNATIONAL JOURNAL OF STROKE (2013) [E3]
Author URL
CitationsScopus - 2
Co-authorsGregory Carter, Parker Magin
2013Nyholt DR, Low S-K, Anderson CA, Painter JN, Uno S, Morris AP, et al., 'Meta-Analysis of GWA Studies Identifies New Endometriosis Risk Loci', REPRODUCTIVE SCIENCES, Orlando, FL (2013) [E3]
Author URL
Co-authorsRodney Scott, Liz Holliday
2012White JH, Magin PJ, Attia JR, Sturm J, Carter GL, McElduff P, Pollack MR, 'Trajectories of psychological distress: A longitudinal cohort study', Neurorehabilitation & Neural Repair: WCNR 2012 Oral Abstracts, Melbourne, VIC (2012) [E3]
Co-authorsGregory Carter, Parker Magin
2012White JH, Magin PJ, Attia JR, Sturm J, Carter GL, McElduff P, Pollack MR, 'Exploring post stroke changes in community dwelling stroke survivors: A mixed methods longitudinal cohort study', Neurorehabilitation & Neural Repair: WCNR 2012 Oral Abstracts, Melbourne, VIC (2012) [E3]
Co-authorsGregory Carter, Parker Magin
2012Islam MR, Khan I, Hassan SMN, McEvoy MA, D'Este CA, Attia JR, et al., 'Association between hypertension and chronic exposure in Bangladesh', Hypertension, Washington, DC (2012) [E3]
Co-authorsMilton Hasnat, Catherine Deste
2012Minelli C, Gogele M, Thakkinstian A, Yurkiewich A, Pattaro C, Pramstaller PP, et al., 'Methods for meta-analyses of genome-wide association studies: Critical assessment of empirical evidence', Genetic Epidemiology, Heidelberg, Germany (2012) [E3]
2012Holliday S, Magin PJ, Dunbabin JS, Oldmeadow CJ, Henry J-M, Lintzeris N, et al., 'Motivating factors amongst NSW general practitioners regarding the prescription of opioid substitution therapy', Drug and Alcohol Review, Melbourne, Australia (2012) [E3]
CitationsWeb of Science - 1
Co-authorsChristopher Oldmeadow, Parker Magin
2012Ewald BD, McElduff P, Attia JR, 'How many steps are enough? Dose response curves for objectively measured physical activity in an Australian community based sample', Journal of Science and Medicine in Sport, Sydney, Australia (2012) [E3]
Co-authorsBen Ewald
2012Talseth-Palmer B, Holliday EG, Evans T-J, McEvoy MA, Attia JR, Grice DM, et al., 'A genome-wide CNV association study of Australian HNPCC/Lynch syndrome patients', Proceedings of the Australian Health & Medical Research Congress 2012, Adelaide, SA (2012) [E3]
Co-authorsRodney Scott, Bente Talseth-Palmer, Liz Holliday
2012Ranasinghe WKB, Attia JR, Oldmeadow CJ, Lawrentschuk N, Robertson J, Ranasinghe T, et al., 'Bladder carcinoma in situ in Australia: A rising incidence for an under-reported malignancy', Asia-Pacific Journal of Clinical Oncology, Darling Harbour, Sydney (2012) [E3]
CitationsScopus - 1
Co-authorsChristopher Oldmeadow
2011Courtney RJ, Paul CL, Sanson-Fisher RW, Macrae FA, Carey ML, Attia JR, McEvoy MA, 'Colorectal cancer screening in Australia: A community-level perspective', Asia-Pacific Journal of Clinical Oncology: COSA 38th Annual Scientific Meeting Poster Abstracts, Perth, WA (2011) [E3]
DOI10.5694/mja11.10661
Co-authorsRob Sanson-Fisher, Mariko Carey, Chris Paul
2011Maguire JM, Holliday EG, Sturm J, Golledge J, Lewis M, Koblar S, et al., 'Australian stroke genetics collaborative: Genetic associations with ischaemic stroke functional outcome', International Journal of Stroke, Adelaide, SA (2011) [E3]
Co-authorsChris Levi, Liz Holliday, Rodney Scott, Mark Parsons, Pablo Moscato, Lisa Lincz, Jane Maguire
2011Russell ML, Evans MK, Royan AT, Magin PJ, Lasserson D, Attia JR, et al., 'Referral and triage of patients with TIAs to an acute access clinic: Risk-stratification performance in an Australian setting', International Journal of Stroke, Adelaide, SA (2011) [E3]
Co-authorsNeil Spratt, Chris Levi, Parker Magin, Mark Parsons
2011White JH, Magin PJ, Attia JR, Sturm J, Carter GL, Pollack MR, 'Trajectories of psychological distress after stroke: A longitudinal, mixed methods cohort study', Stroke Society of Australasia Annual Scientific Meeting 2011 (SSA-ASM), Adelaide, SA (2011) [E3]
Co-authorsParker Magin, Gregory Carter
2011Thomas L, Rivett DA, Levi CR, 'Risk factors and clinical presentation of craniocervical arterial dissection. A prospective study: Preliminary results', Physiotherapy: Abstracts, World Physical Therapy 2011, Amsterdam (2011) [E3]
CitationsScopus - 5Web of Science - 4
Co-authorsLucy Thomas, Chris Levi, Darren Rivett
2011Khan I, Hassan S, McEvoy MA, D'Este CA, Attia JR, Peel R, Hasnat MA, 'Association between type 2 diabetes and chronic arsenic exposure in Bangladesh', Epidemiology, - (2011) [E3]
CitationsWeb of Science - 2
Co-authorsMilton Hasnat, Roseanne Peel, Catherine Deste
2011Nickel J, Attia JR, Anothaisintawee T, Thakkinstian A, 'a-blockers, antibiotics and anti-inflammatories have a role in management of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS)', Urology, Berlin, Germany (2011) [E3]
2011Allen J, Inder KJ, Kelly BJ, Attia JR, Lewin TJ, 'An interaction of social support and remoteness in the prediction of psychological distress', Journal of Epidemiology and Community Health, Edinburgh (2011) [E3]
Co-authorsTerry Lewin, Brian Kelly, Kerry Inder
2011White JH, Magin PJ, Attia JR, Sturm J, Carter GL, Fitzgerald MN, et al., 'Post-stroke depression and anxiety: A longitudinal cohort study', Journal of Neurology, Lisbon, Portugal (2011) [E3]
Co-authorsGregory Carter, Parker Magin
2011Ambikaipaker V, Mathew A, Attia JR, 'Serum tumour markers: a retrospective analysis. A guide in using serum tumour markers in predicting malignancy', Journal of Gastroenterology and Hepatology, Brisbane, QLD (2011) [E3]
2011Holland R, Dunlop AJ, Hinman J, Ribbons K, Sadler CW, Gill AJ, et al., 'Buprenorphine-naloxone vs wait list control RCT: Health service utilisation and health economic outcomes', Drug and Alcohol Review, Hobart, Australia (2011) [E3]
2011Holliday S, Magin PJ, Dunlop AJ, Dunbabin JS, Henry J, Goode SM, et al., 'Opioid analgesics in chronic non-cancer pain: A quality use of medicines study', Drug and Alcohol Review, Hobart, Australia (2011) [E3]
Co-authorsParker Magin
2011White JH, Magin PJ, Attia JR, Sturm J, Carter GL, Fitzgerald MN, et al., 'Post-stroke depression and anxiety: A longitudinal cohort study', Cerebrovascular Diseases, Hamburg, Germany (2011) [E3]
Co-authorsParker Magin, Gregory Carter
2011Gupta S, Lewis G, Rogers K, Attia J, 'QUANTITATIVE RENAL TRANSPLANT SCINTIGRAPHY: PATHOLOGICAL CORRELATION (ANZAPNM Award Entry)', INTERNAL MEDICINE JOURNAL (2011) [E3]
Author URL
2010Murphy VE, Namazy JA, Powell GH, Gibson PG, Chambers C, Attia JR, Schatz M, 'A meta-analysis of adverse perinatal outcomes in asthmatic women: Effect of asthma on placental and neonatal outcomes', American Journal of Respiratory and Critical Care Medicine, New Orleans (2010) [E3]
Co-authorsPeter Gibson, Vanessa Murphy
2010Miles S, Rogers K, Thomas P, Allen L, Soans B, Abel C, et al., 'Comparing the reliability of reporting of single photon emission computed tomography ventilation-perfusion scintigraphy (SPECT-VQ) and CT pulmonary angiogram (CTPA) in pulmonary embolism (PE) diagnosis', European Respiratory Society Annual Congress 2010. Abstracts, Barcelona, Spain (2010) [E3]
Co-authorsMichael Hensley, Catherine Deste
2010White JH, Magin PJ, Attia JR, Sturm J, Pollack MR, 'Exploring goal setting in stroke survivors: a prospective study', Cerebrovascular Diseases: European Stroke Conference, Barcelona, Spain (2010) [E3]
Co-authorsParker Magin
2010White JH, Magin PJ, Attia JR, Sturm J, McElduff P, Pollack MR, 'Exploring post-stroke mood changes in community-dwelling stroke survivors: a prospective qualitative study', Cerebrovascular Diseases: European Stroke Conference, Barcelona, Spain (2010) [E3]
Co-authorsParker Magin
2010White JH, Magin PJ, Attia JR, Sturm J, McElduff P, Pollack MR, 'Exploring post-stroke mood changes in community-dwelling stroke survivors: a longitudinal cohort study', Cerebrovascular Diseases: European Stroke Conference, Barcelona, Spain (2010) [E3]
Co-authorsParker Magin
2010White J, Miller B, Magin PJ, Attia JR, Sturm J, 'Access and participation in the community: A prospective cohort qualitative study of driving post-stroke', Cerebrovascular Diseases: European Stroke Conference, Barcelona, Spain (2010) [E3]
Co-authorsParker Magin
2010Maguire JM, Thakkinstian A, Levi CR, Lincz L, Bissett KE, Sturm J, et al., 'Genetic influences on ischemic stroke 90-day functional outcome: A novel association', Circulation, Beijing (2010) [E3]
Co-authorsLisa Lincz, Jane Maguire, Rodney Scott, Chris Levi
2010Hiles SA, Attia JR, Baker AL, 'Changes in interleukin-6, C-reactive protein and interleukin-10 in people with depression following antidepressant treatment: A meta-analysis', Brain, Behavior, and Immunity, Dublin, Ireland (2010) [E3]
Co-authorsAmanda Baker
2010Hiles SA, Attia JR, Baker AL, 'Interleukin-6 in people with and without depression: Exploring moderators using meta-analytic techniques', Brain, Behavior, and Immunity, Dublin, Ireland (2010) [E3]
Co-authorsAmanda Baker
2010Dunlop A, Lintzeris N, Gill T, Sadler C, Ribbons K, Attia J, et al., 'EFFECTIVENESS AND COST EFFECTIVENESS OF UNSUPERVISED BUPRENORPHINE-NALOXONE VERSUS WAIT LIST CONTROL RCT', DRUG AND ALCOHOL REVIEW (2010) [E3]
Author URL
2010Murphy VE, Namazy J, Powell GH, Gibson PG, Chambers C, Attia JR, Schatz M, 'A meta-analysis of adverse perinatal outcomes in asthmatic women: Effect of asthma on maternal and neonatal outcomes', Respirology, Brisbane, QLD (2010) [E3]
Co-authorsVanessa Murphy, Peter Gibson
2010Murphy VE, Namazy J, Powell GH, Schatz M, Chambers C, Attia JR, Gibson PG, 'A meta-analysis of adverse perinatal outcomes in asthmatic women: Effect of asthma on size at birth and timing of birth', Respirology, Brisbane, QLD (2010) [E3]
Co-authorsVanessa Murphy, Peter Gibson
2010Talseth-Palmer B, Holliday EG, Evans T-J, McPhillips M, McEvoy MA, Attia JR, Scott R, 'A modern approach to the search for modifying genetic loci infleuncing the high breast cancer incidence seen in an Australian HNPCC/Lynch Syndrome cohort', Proceedings of the Australian Health and Medical Research Congress 2010, Melbourne, Vic (2010) [E3]
Co-authorsLiz Holliday, Rodney Scott, Bente Talseth-Palmer
2010Ranasinghe WKB, Wright T, Doyle TE, Attia JR, McElduff P, Persad R, 'Bariatric surgery: An added benefit for obese females with urinary incontinence?', BJU International, Manchester, UK (2010) [E3]
2009Henry D, Lincz L, Attia JR, McElduff P, Bisset L, Peel R, et al., 'Polymorphisms in two regions of the cyclo-oxygenase-2 gene associated with variation in risk of coronary thrombosis with cyclo-oxygenase-2 inhibitors', Basic & Clinical Pharmacology & Toxicology, Edinburgh, UK (2009) [E3]
DOI10.1111/j.1742-7843.2009.00436.x
Co-authorsRoseanne Peel, Lisa Lincz
2009Osmotherly PG, Attia JR, McElduff P, 'The composite neck pain and disability questionnaire: Development and factor structure', Australian Journal of Physiotherapy: eSupplements, Sydney, NSW (2009) [E3]
Co-authorsPeter Osmotherly
2009Pickering PM, Osmotherly PG, Attia JR, McElduff P, 'An examination of outcome measures for pain and dysfunction in the cervical spine: A factor analysis', Australian Journal of Physiotherapy: eSupplements, Sydney, NSW (2009) [E3]
Co-authorsPeter Osmotherly
2009Maguire J, Thakkinstian A, Attia JR, Lincz L, Bisset L, Sturm J, et al., 'Impact of COX-2 RS5275, RS20417 and GPIIIA RS5918 polymorphisms on 90 day ischaemic stroke functional outcome: A novel association', Cerebrovascular Diseases, Stockholm, Sweden (2009) [E3]
DOI10.1159/000221772
Co-authorsChris Levi, Lisa Lincz, Rodney Scott
2009Jones LJ, Craven PD, Attia JR, Thakkinstian A, Wright IM, 'Administration of intravenous ibuprofen for significant PDA in preterm infants at greater than 24 h of life: Does it increase the risk of chronic lung disease (CLD)?', Journal of Paediatrics and Child Health, Darwin, NT (2009) [E3]
DOI10.1111/j.1440-1754.2009.01475.x
Co-authorsIan Wright
2009Henry D, Lincz L, Attia J, McElduff P, Bisset L, Peel R, et al., 'Polymorphisms in Two Regions of the Cyclo-Oxygenase-2 Gene Associated with Variation in Risk of Coronary Thrombosis with Cyclo-Oxygenase-2 Inhibitors', PHARMACOEPIDEMIOLOGY AND DRUG SAFETY (2009) [E3]
Author URL
Co-authorsRoseanne Peel, Lisa Lincz
2008Jones LJ, Craven PD, Attia JR, Wright I, 'Early targeted indomethacin: Where is the evidence?', Journal of Paediatrics and Child Health, Gold Coast, QLD (2008) [E3]
DOI10.1111/j.1440-1754.2008.01297.x
2008Miles S, Rogers K, Thomas P, Soans B, Attia JR, Abel C, et al., 'Lung single photon emission computed tomography (SPECT): A useful tool for diagnosing pulmonary embolism', Respirology, Melbourne, VIC (2008) [E3]
DOI10.1111/j.1440-1843.2008.01252_9.x
Co-authorsCatherine Deste, Michael Hensley
2008Boggess MM, Guest M, D'Este CA, Attia JR, 'Statistical methods to compare hearing thresholds to ISO-7029', Occupational & Environmental Medicine, Costa Rica (2008) [E3]
Co-authorsMaya Guest, Catherine Deste
2008Guest M, D'Este CA, Attia JR, Boggess MM, 'Impairment of hearing and balance in aircraft maintenance technicians', Occupational & Environmental Medicine, Costa Rica (2008) [E3]
Co-authorsCatherine Deste, Maya Guest
2008Wood LG, Attia JR, McElduff P, McEvoy MA, Flood V, Gibson PG, 'Dietary fat and an activated innate immune response are associated with reduced FEV1', Asia Pacific Journal of Clinical Nutrition, Adelaide, SA (2008) [E3]
Co-authorsPeter Gibson, Lisa Wood
2008White JH, Magin PJ, Pollack MR, Attia JR, Sturm J, 'The long-term experience of altered mood in community dwelling stroke survivors: Methodology and preliminary findings of a longitudinal qualitative study', 2008 General Practice & Primary Health Care Research Conference: Program & Abstracts, Hobart, TAS (2008) [E3]
Co-authorsParker Magin
2008Ashton KA, Proietto AM, Otton GR, Symonds IM, McEvoy MA, Attia JR, et al., 'Combined tp53 r72p and mdm2 snp309 genotypes are associated with high grade endometrial cancer', ASMR XVII NSW Scientific Meeting: Programme and Abstracts, Sydney, NSW (2008) [E3]
Co-authorsKatie Ashton, Rodney Scott, Ian Symonds
2008Oakley PW, Nair BR, Attia JR, 'Teaching hospital based formative assessment can predict Trainee performance in RACP written examination', ANZAME Conference 2008. Conference Program, Abstracts and Papers, Sydney, NSW (2008) [E3]
2007Maguire J, Sturm J, Attia JR, Whyte S, Bisset L, Lincz L, et al., 'A case-control genetic association study to examine platelet glycoprotein polymorphisms and ischaemic stroke risk', Internal Medicine Journal, Perth, Australia (2007) [E3]
Co-authorsLisa Lincz, Mark Parsons, Chris Levi
2006D'Este C, Attia J, Brown A, Schofield P, Tavener M, Gibson R, Horsley K, 'SHOAMP: The study of health outcomes in aircraft maintenance personnel.', NEUROTOXICOLOGY, Res Triangle Park, NC (2006)
Author URL
Co-authorsCatherine Deste, Peter Schofield
2006Ronan A, Thakkinstian A, Zakaria S, Settakorn J, Moscovis SM, Scott R, et al., 'The role of MTHFR polymorphisms and dietary folate in childhood cancer', Program of the 11th International Congress of Human Genetics, Brisbane, QLD (2006) [E3]
Co-authorsRodney Scott
2005Guest M, Wigney DJ, Attia JR, D'Este CA, Brown A, Boggess M, 'Hearing Loss in Australian Military Aircraft Personnel', AIOH : 23rd Annual Conference of the Australian Institute of Occupational Hygienists & Annual General Meeting : conference proceedings : 3rd to 7th December 2005, Crowne Plaza, Terrigal, N.S.W, Crown Plaza, Terrigal (2005) [E2]
Co-authorsCatherine Deste, Maya Guest
2003Osmotherly PG, Attia JR, 'Deep cervical flexor muscle performance and neck pain in call centre operators - a pilot study', Musculoskeletal Physiotherapy Australia 13th Biennial Conference, Sydney, Australia (2003) [E3]
Co-authorsPeter Osmotherly
2003Wang Y, Levi CR, D'Este CA, Attia JR, Spratt N, Fisher J, 'Seasonal variation in stroke in the Hunter Region, Australia a five-year hospital-based study, 1995-2000', STROKE, PHOENIX, ARIZONA (2003)
Author URL
Co-authorsCatherine Deste, Neil Spratt, Chris Levi
2003Thakkinstian A, D'Este C, Eisman J, Nguyen T, Attia J, 'Meta-analysis of molecular association studies: The vitamin D receptor gene polymorphisms and bone mineral density as a case study.', JOURNAL OF BONE AND MINERAL RESEARCH, MINNEAPOLIS, MINNESOTA (2003)
Author URL
Co-authorsCatherine Deste
Show 68 more conferences

Report (2 outputs)

YearCitationAltmetricsLink
2014Gwynn JD, Blunden SV, Turner N, Flood V, Attia J, Smith W, et al., 'Many Rivers Diabetes Prevention Project: An Aboriginal community governed program of research and health promotion for children. Final Report August 2014', NSW MInistry of Health (2014) [R1]
Co-authorsJohn Wiggers, Catherine Deste, Josephine Gwynn, Wayne Smith
2014Gwynn JD, Blunden SV, Turner N, Flood V, Attia J, Smith W, et al., 'Many Rivers Diabetes Prevention Project: An Aboriginal community governed program of research and health promotion for children. Short Report.', NSW MInistry of Health, 27 (2014) [R1]
Co-authorsJosephine Gwynn, Wayne Smith, John Wiggers, Catherine Deste
Edit

Grants and Funding

Summary

Number of grants67
Total funding$13,183,372

Click on a grant title below to expand the full details for that specific grant.


20151 grants / $1,031,671

Helping stroke physicians choose who to thrombolyse - the "Targeting Optimal Thrombolysis Outcomes" (TOTO) study$1,031,671

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project TeamDoctor Liz Holliday, Professor John Attia, Associate Professor Vincent Thijs, Dr Simon Koblar, Conjoint Associate Professor Jonathan Sturm, Associate Professor Jane Maguire, Doctor Lisa Lincz
SchemeProject Grant
RoleInvestigator
Funding Start2015
Funding Finish2015
GNoG1400237
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

20147 grants / $2,639,712

Does pneumococcal vaccination protect against cardiovascular disease? $1,815,627

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project TeamProfessor John Attia, Professor Catherine D'Este, Dr Walter Abhayaratna, Professor Andrew Tonkin, Conjoint Professor Chris Levi, Conjoint Professor David Durrheim, Professor Joseph Hung, Mr Mark McEvoy, Doctor Alexis Hure
SchemeProject Grant
RoleLead
Funding Start2014
Funding Finish2014
GNoG1300127
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

Reducing unnecessary ordering of pathology tests in hospitalised patients$372,927

Funding body: HCF Health and Medical Research Foundation

Funding bodyHCF Health and Medical Research Foundation
Project TeamProfessor John Attia, Conjoint Professor Christopher Doran, Conjoint Associate Professor Andrew Searles, Laureate Professor Robert Sanson-Fisher, Conjoint Professor Anne Duggan, Conjoint Associate Professor Huy Tran, Mr Nigel Lyons, Ms Tracy McCosker, Doctor Alexis Hure
SchemeHealth Services Research Grants Program
RoleLead
Funding Start2014
Funding Finish2014
GNoG1301000
Type Of FundingAust Competitive - Non Commonwealth
Category1NS
UONY

Evaluation of a tailored online hospital and post-discharge smoking cessation program for orthopaedic trauma surgery patients$364,658

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project TeamAssociate Professor Billie Bonevski, Professor Zsolt Balogh, Professor Amanda Baker, Professor Ian Harris, Professor John Attia, Conjoint Professor Christopher Doran, Dr Johnson George, Doctor Luke Wolfenden
SchemePartnership Projects
RoleInvestigator
Funding Start2014
Funding Finish2014
GNoG1300686
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

Genetic and Environmental Determinants of Depressive Symptoms: Trajectory and Outcomes in a Longitudinal Population Data Set$30,000

Funding body: Hunter Medical Research Institute

Funding bodyHunter Medical Research Institute
Project TeamProfessor Brian Kelly, Associate Professor Paul Tooney, Professor Rodney Scott, Professor John Attia, Conjoint Associate Professor Murray Cairns, Professor Vaughan Carr
SchemeProject Grant
RoleInvestigator
Funding Start2014
Funding Finish2014
GNoG1400594
Type Of FundingGrant - Aust Non Government
Category3AFG
UONY

Biological characterisation of genetic associations for large artery atherosclerotic stroke$25,000

Funding body: Hunter Medical Research Institute

Funding bodyHunter Medical Research Institute
Project TeamDoctor Liz Holliday, Professor Rodney Scott, Conjoint Professor Chris Levi, Professor John Attia, Associate Professor Jane Maguire
SchemeStroke Research Project Grant
RoleInvestigator
Funding Start2014
Funding Finish2014
GNoG1301340
Type Of FundingGrant - Aust Non Government
Category3AFG
UONY

The role of perceived stress on the onset of type 2 diabetes in women.$21,500

Funding body: John Hunter Hospital Charitable Trust Fund

Funding bodyJohn Hunter Hospital Charitable Trust Fund
Project TeamDoctor Melissa Harris, Professor John Attia, Doctor Judy Luu, Associate Professor Deb Loxton
SchemeResearch Grant
RoleInvestigator
Funding Start2014
Funding Finish2014
GNoG1301440
Type Of FundingOther Public Sector - State
Category2OPS
UONY

A descriptive observational study of infants aged < 24 months with severe bronchiolitis requiring critical care$10,000

Funding body: Hunter Medical Research Institute

Funding bodyHunter Medical Research Institute
Project TeamMrs Elizabeth Kepreotes, Professor Joerg Mattes, Doctor Peter Harrigan, Conjoint Associate Professor Bruce Whitehead, Professor John Attia, Doctor Mark Lee
SchemeCritical Care and HMRI BRICs Nursing Research and Innovation Grant
RoleInvestigator
Funding Start2014
Funding Finish2014
GNoG1401451
Type Of FundingGrant - Aust Non Government
Category3AFG
UONY

20134 grants / $145,000

A genome wide association study on childhood brain tumours$110,000

Funding body: Hunter Medical Research Institute

Funding bodyHunter Medical Research Institute
Project TeamProfessor Rodney Scott, Doctor Frank Alvaro, Miss Tiffany Evans, Professor John Attia, Doctor Liz Holliday, Dr Elizabeth Milne, Professor Bruce Armstrong
SchemeResearch Grant
RoleInvestigator
Funding Start2013
Funding Finish2013
GNoG1301149
Type Of FundingGrant - Aust Non Government
Category3AFG
UONY

Hunter Community Study$15,000

Funding body: Hunter Medical Research Institute

Funding bodyHunter Medical Research Institute
Project TeamProfessor John Attia
SchemeProject Grant
RoleLead
Funding Start2013
Funding Finish2013
GNoG1300200
Type Of FundingContract - Aust Non Government
Category3AFC
UONY

The genetic determinants of brain haemorrhage associated with stroke thrombolysis$10,000

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamConjoint Professor Chris Levi, Professor John Attia, Doctor Liz Holliday, Dr Simon Koblar, Professor Rodney Scott, Conjoint Associate Professor Jonathan Sturm, Associate Professor Jonathan Rosand, Doctor Lisa Lincz, Associate Professor Jane Maguire
SchemeNear Miss Grant
RoleInvestigator
Funding Start2013
Funding Finish2013
GNoG1300475
Type Of FundingInternal
CategoryINTE
UONY

The genetic determinants of brain haemorrhage associated with stroke thrombolysis$10,000

Funding body: Hunter Medical Research Institute

Funding bodyHunter Medical Research Institute
Project TeamConjoint Professor Chris Levi, Professor John Attia, Doctor Liz Holliday, Dr Simon Koblar, Professor Rodney Scott, Conjoint Associate Professor Jonathan Sturm, Associate Professor Jonathan Rosand, Doctor Lisa Lincz, Associate Professor Jane Maguire
SchemeNear Miss
RoleInvestigator
Funding Start2013
Funding Finish2013
GNoG1300704
Type Of FundingGrant - Aust Non Government
Category3AFG
UONY

20125 grants / $1,161,118

An olfactory 'stress test' for early detection of Alzheimer's disease$756,087

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project TeamConjoint Associate Professor Peter Schofield, Professor John Attia, Professor Alison Jones, Conjoint Associate Professor Grant Bateman
SchemeProject Grant
RoleInvestigator
Funding Start2012
Funding Finish2012
GNoG1100221
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

Double blind randomised controlled trial of electronic alcohol screening and brief intervention (e-SBI) for hospital outpatients$359,031

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project TeamProfessor Kypros Kypri, Doctor Natalie Johnson, Professor John Saunders, Professor Richard Saitz, Professor John Attia
SchemeProject Grant
RoleInvestigator
Funding Start2012
Funding Finish2012
GNoG1100111
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

Validation of the food frequency questionnaire used in the Hunter Community Study using carotenoids and fatty acids$25,000

Funding body: John Hunter Hospital Charitable Trust Fund

Funding bodyJohn Hunter Hospital Charitable Trust Fund
Project TeamDoctor Alexis Hure, Professor John Attia, Mr Mark McEvoy
SchemeResearch Grant
RoleInvestigator
Funding Start2012
Funding Finish2012
GNoG1200266
Type Of FundingOther Public Sector - State
Category2OPS
UONY

The genetic determinants of brain haemorrhage associated with stroke thrombolysis$20,000

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamConjoint Professor Chris Levi, Professor John Attia, Doctor Liz Holliday, Professor Rodney Scott, Conjoint Associate Professor Jonathan Sturm, Doctor Lisa Lincz
SchemeNear Miss Grant
RoleInvestigator
Funding Start2012
Funding Finish2012
GNoG1200675
Type Of FundingInternal
CategoryINTE
UONY

Plasma protein profiles in normal brain ageing and early stages of dementia$1,000

Funding body: ARC (Australian Research Council)

Funding bodyARC (Australian Research Council)
Project TeamProfessor Perminder Sachdev, Dr Anne Poljak, Professor John Attia, Conjoint Associate Professor Peter Schofield, Dr John Crawford, Professor Mark Duncan
SchemeDiscovery Projects
RoleLead
Funding Start2012
Funding Finish2012
GNoG1200767
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

20111 grants / $1,075,461

Implementation of quality use of advanced CT imaging in acute stroke$1,075,461

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project TeamProfessor Mark Parsons, Conjoint Professor Chris Levi, Professor Geoff Donnan, Professor Stephen Davis, Professor John Attia, Professor Christopher Bladin, Mr Qing Yang, Associate Professor Peter Mitchell, Associate Professor Stacy Goergen, Professor Ramamohanarao Kotagiri
SchemePartnership Projects
RoleInvestigator
Funding Start2011
Funding Finish2011
GNoG1000535
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

201010 grants / $1,915,695

Evaluating the effectiveness of a strategy to increase the adoption of best evidence practice. A cluster randomised controlled trial in acute stroke care$772,950

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project TeamLaureate Professor Robert Sanson-Fisher, Conjoint Professor Chris Levi, Associate Professor Christine Paul, Conjoint Professor Cate d'Este, Professor Mark Parsons, Professor Christopher Bladin, Professor Richard Lindley, Professor John Attia
SchemePartnership Projects
RoleInvestigator
Funding Start2010
Funding Finish2010
GNoG0189781
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

Men, Depression and Social Networks in Rural Communities: Linking Epidemiologic Evidence to Effective Interventions$324,809

Funding body: Beyond Blue Ltd

Funding bodyBeyond Blue Ltd
Project TeamProfessor Brian Kelly, Professor John Attia, Doctor Frances Kay-Lambkin, Conjoint Associate Professor Terry Lewin, Professor Amanda Baker, Mr Trevor Hazell, Doctor Kerry Inder
SchemeResearch Grant
RoleInvestigator
Funding Start2010
Funding Finish2010
GNoG1000456
Type Of FundingContract - Aust Non Government
Category3AFC
UONY

Xstrata Coal Fellow in Depression$300,000

Funding body: Xstrata Coal Australia Pty Ltd

Funding bodyXstrata Coal Australia Pty Ltd
Project TeamProfessor Brian Kelly, Professor John Attia, Doctor Frances Kay-Lambkin, Conjoint Associate Professor Terry Lewin, Professor Amanda Baker, Mr Trevor Hazell, Doctor Kerry Inder
SchemeXstrata Coal Fellow in Depression
RoleInvestigator
Funding Start2010
Funding Finish2010
GNoG0900102
Type Of FundingContract - Aust Non Government
Category3AFC
UONY

Genetic associations of early retinal pathologic phenotypes: Data pooling and meta-analyses of multiple populations$182,438

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project TeamAssociate Professor Jie Wang, Professor Eric Boerwinkle, Dr Gerald Liew, Professor Pablo Moscato, Dr Shyong Tai, Dr Alexander Hewitt, Professor John Attia, Associate Professor Yik Teo, Professor Ronald Klein, Doctor Patrick McElduff
SchemeProject Grant
RoleLead
Funding Start2010
Funding Finish2010
GNoG1101153
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

Experimental Studies of the Effects of the Research Process on Participant Behaviour$178,000

Funding body: ARC (Australian Research Council)

Funding bodyARC (Australian Research Council)
Project TeamProfessor Kypros Kypri, Dr Jim McCambridge, Professor John Attia, Mr Steven Bowe
SchemeDiscovery Projects
RoleInvestigator
Funding Start2010
Funding Finish2010
GNoG0190025
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

Persistence of depressive symptoms and factors associated with depressive symptoms, across urban, rural and regional communities$52,500

Funding body: Australian Rotary Health

Funding bodyAustralian Rotary Health
Project TeamProfessor Brian Kelly, Professor John Attia, Doctor Kerry Inder
SchemeMental Health Research Grant
RoleInvestigator
Funding Start2010
Funding Finish2010
GNoG0900233
Type Of FundingAust Competitive - Non Commonwealth
Category1NS
UONY

Evaluating the effectiveness of a strategy to increase the adoption of best evidence practice. A cluster randomised controlled trial in acute stroke care $50,000

Funding body: Victorian Department of Health

Funding bodyVictorian Department of Health
Project TeamLaureate Professor Robert Sanson-Fisher, Conjoint Professor Chris Levi, Associate Professor Christine Paul, Conjoint Professor Cate d'Este, Professor Mark Parsons, Professor Christopher Bladin, Professor Richard Lindley, Professor John Attia
SchemeProject Grant
RoleInvestigator
Funding Start2010
Funding Finish2010
GNoG1100824
Type Of FundingOther Public Sector - State
Category2OPS
UONY

Implementation of thrombolytic therapy in acute stroke. A cluster randomised trial$30,000

Funding body: BellBerry Limited

Funding bodyBellBerry Limited
Project TeamConjoint Professor Chris Levi, Professor John Attia, Associate Professor Christine Paul, Professor Mark Parsons, Professor Christopher Bladin, Professor Richard Lindley, Conjoint Professor Cate d'Este
SchemeNear Miss
RoleInvestigator
Funding Start2010
Funding Finish2010
GNoG0900221
Type Of FundingGrant - Aust Non Government
Category3AFG
UONY

Zinc as a target for prevention of type-2 diabetes$15,000

Funding body: Hunter Children`s Research Foundation

Funding bodyHunter Children`s Research Foundation
Project TeamProfessor John Attia, Doctor Milton Hasnat, Mr Mark McEvoy, Doctor Amanda Patterson, Doctor Sham Acharya, Mr Steven Bowe
SchemeResearch Grant
RoleLead
Funding Start2010
Funding Finish2010
GNoG1000450
Type Of FundingContract - Aust Non Government
Category3AFC
UONY

Genetic influences in colorectal cancer: a global consortium$9,998

Funding body: Hunter Children`s Research Foundation

Funding bodyHunter Children`s Research Foundation
Project TeamProfessor Rodney Scott, Professor John Attia, Mr Mark McEvoy
SchemeResearch Grant
RoleInvestigator
Funding Start2010
Funding Finish2010
GNoG0900152
Type Of FundingGrant - Aust Non Government
Category3AFG
UONY

20095 grants / $1,419,923

Australian stroke genetics collaborative - Genome-wide association study in ischaemic stroke$1,108,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project TeamConjoint Professor Chris Levi, Conjoint Associate Professor Jonathan Sturm, Professor John Attia, Professor Rodney Scott, Doctor Lisa Lincz, Dr Simon Koblar, Professor Pablo Moscato
SchemeProject Grant
RoleInvestigator
Funding Start2009
Funding Finish2009
GNoG0188856
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

LDX analyser (fingerprick unit) x4, piCo Smokerlyzer (Carboxymeter)x4, Universal cardboard disposable mouthpieces for piCo smokerlyzer x4 and Universal d pieces for piCo Smokerlyzer x4$20,775

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project TeamProfessor Amanda Baker, Doctor Frances Kay-Lambkin, Doctor Alyna Turner, Doctor Juanita Todd, Professor Robin Callister, Ms Sally Hunt, Professor Brian Kelly, Professor John Attia, Associate Professor Jennifer Bowman, Doctor Paula Wye
SchemeEquipment Grant
RoleInvestigator
Funding Start2009
Funding Finish2009
GNoG0189849
Type Of FundingOther Public Sector - Commonwealth
Category2OPC
UONY

Development and transfer of data linkage key and dataset for SHOAMP data and blood samples$13,387

Funding body: Department of Veterans` Affairs

Funding bodyDepartment of Veterans` Affairs
Project TeamConjoint Professor Cate d'Este, Professor John Attia
SchemeResearch Grant
RoleInvestigator
Funding Start2009
Funding Finish2009
GNoG1000008
Type Of FundingOther Public Sector - Commonwealth
Category2OPC
UONY

Vascular Ischaemia Study$10,400

Funding body: Hunter Medical Research Institute

Funding bodyHunter Medical Research Institute
Project TeamConjoint Professor Chris Levi, Professor John Attia, Professor Rodney Scott, Doctor Michael Seldon, Doctor Lisa Lincz, Conjoint Associate Professor Jonathan Sturm
SchemeResearch Grant
RoleInvestigator
Funding Start2009
Funding Finish2009
GNoG0900120
Type Of FundingContract - Aust Non Government
Category3AFC
UONY

20082 grants / $861,224

Genes and environment in the risk of early age-related macular degeneration: a population-based case-control study$701,224

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project TeamProfessor John Attia, Conjoint Professor Wayne Smith, Professor Pablo Moscato
SchemeProject Grant
RoleLead
Funding Start2008
Funding Finish2008
GNoG0189168
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

HMRI Senior Research Fellow$160,000

Funding body: Hunter Medical Research Institute

Funding bodyHunter Medical Research Institute
Project TeamProfessor John Attia, Emeritus Professor Maree Gleeson, Professor Rodney Scott, Conjoint Professor Vaughan Carr, Conjoint Professor Stephen Ackland, Professor Michael Hazelton, Professor Trevor Day
SchemeSenior Fellowship
RoleLead
Funding Start2008
Funding Finish2008
GNoG0188558
Type Of FundingContract - Aust Non Government
Category3AFC
UONY

20077 grants / $219,708

Systematic Review of the effects of Long Work Hours on Workplace Safety & Performance$69,000

Funding body: National Occupational Health & Safety Commission

Funding bodyNational Occupational Health & Safety Commission
Project Team
SchemeTender
RoleInvestigator
Funding Start2007
Funding Finish2007
GNo
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

Prevention of heart disease by pneumococcal vaccination$50,000

Funding body: Pfizer Australia

Funding bodyPfizer Australia
Project TeamProfessor Phil Hansbro, Dr Sukumaran Thambar, Professor John Attia, Mr Mark McEvoy
SchemeCardiovascular Lipid Research Grants
RoleInvestigator
Funding Start2007
Funding Finish2007
GNoG0186642
Type Of FundingAust Competitive - Non Commonwealth
Category1NS
UONY

Cancer Cluster Study$48,030

Funding body: Newcastle Innovation

Funding bodyNewcastle Innovation
Project TeamDoctor Maya Guest, Ms Sandra McBurnie, Professor John Attia, Conjoint Professor Cate d'Este
SchemeAdministered Research
RoleInvestigator
Funding Start2007
Funding Finish2007
GNoG0188347
Type Of FundingInternal
CategoryINTE
UONY

Healthy Airways and Obstructive Lung Disease (HAROLD)$20,000

Funding body: Hunter Medical Research Institute

Funding bodyHunter Medical Research Institute
Project TeamConjoint Professor Wayne Smith, Associate Professor Lisa Wood, Professor John Attia, Associate Professor Regina Berretta, Professor Pablo Moscato
SchemeProject Grant
RoleInvestigator
Funding Start2007
Funding Finish2007
GNoG0187246
Type Of FundingContract - Aust Non Government
Category3AFC
UONY

Hewlett Packard 7890 series gas chromatograph with accessories$20,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project TeamAssociate Professor Lisa Wood, Conjoint Professor Peter Wark, Conjoint Professor Peter Gibson, Associate Professor Jodie Simpson, Doctor Vanessa Murphy, Laureate Professor Paul Foster, Professor Phil Hansbro, Conjoint Associate Professor Vicki Clifton, Professor Clare Collins, Conjoint Professor Wayne Smith, Professor John Attia
SchemeEquipment Grant
RoleInvestigator
Funding Start2007
Funding Finish2007
GNoG0188191
Type Of FundingOther Public Sector - Commonwealth
Category2OPC
UONY

The impact of Asymmetrical Dimethylarginine on Cognition in a population-based cohort$7,678

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamMr Mark McEvoy, Conjoint Professor Wayne Smith, Conjoint Associate Professor Peter Schofield, Professor John Attia
SchemePilot Grant
RoleInvestigator
Funding Start2007
Funding Finish2007
GNoG0187872
Type Of FundingInternal
CategoryINTE
UONY

Genetic polymorphisms in the native thrombolytic systems as risk factors for ischaemic stroke.$5,000

Funding body: Hunter Medical Research Institute

Funding bodyHunter Medical Research Institute
Project TeamConjoint Professor Chris Levi, Professor John Attia, Professor Rodney Scott, Dr Amanda Thrift
SchemeResearch Grant
RoleInvestigator
Funding Start2007
Funding Finish2007
GNoG0187320
Type Of FundingContract - Aust Non Government
Category3AFC
UONY

20068 grants / $748,641

Prevention of heart disease by pneumococcal vaccination$55,000

Funding body: Pfizer Cardiovascular lipid research grants

Funding bodyPfizer Cardiovascular lipid research grants
Project Team
SchemeCardiovascular Lipid Research Grants
RoleInvestigator
Funding Start2006
Funding Finish2007
GNo
Type Of FundingAust Competitive - Non Commonwealth
Category1NS
UONY

The impact of Anticholinergic activity, apolipoprotein E and high-affinity choline transporter genotype on cognition in a population-based co-hort: a pilot study$15,500

Funding body: Hunter Medical Research Institute

Funding bodyHunter Medical Research Institute
Project TeamMr Mark McEvoy, Conjoint Associate Professor Peter Schofield, Conjoint Professor Wayne Smith, Doctor Janine Duke, Professor John Attia
SchemeProject Grant
RoleInvestigator
Funding Start2006
Funding Finish2006
GNoG0186170
Type Of FundingContract - Aust Non Government
Category3AFC
UONY

The rEMISS Study. Exploring the Experience of Mood Disturbance in community dwelling Stroke Survivors: a longitudinal study$14,500

Funding body: John Hunter Hospital Charitable Trust Fund

Funding bodyJohn Hunter Hospital Charitable Trust Fund
Project Team
SchemeCharitable Trusts and Foundations Project
RoleInvestigator
Funding Start2006
Funding Finish2007
GNo
Type Of FundingAust Competitive - Non Commonwealth
Category1NS
UONY

Is pneumococcal vaccination protective for cardiovascular disease? Elucidating the relationship between pneumococcal vaccination and protective anti-oxidised LDL antibodies$13,448

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamProfessor John Attia
SchemePilot Grant
RoleLead
Funding Start2006
Funding Finish2006
GNoG0186696
Type Of FundingInternal
CategoryINTE
UONY

Elucidating the mechanics of transgenerational toxicity in the ageing male$10,000

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamDoctor Shaun Roman, Professor John Attia, Dr Elizabeth Gillam
SchemeNear Miss Grant
RoleInvestigator
Funding Start2006
Funding Finish2006
GNoG0186080
Type Of FundingInternal
CategoryINTE
UONY

10 year follow-up of patients attending a flexible eating insulin education program$10,000

Funding body: Novo Nordisk Foundation

Funding bodyNovo Nordisk Foundation
Project Team
SchemeProject Grant
RoleInvestigator
Funding Start2006
Funding Finish2007
GNo
Type Of FundingAust Competitive - Non Commonwealth
Category1NS
UONY

Identification of single nucleotide polymorphisms that are associated with an increased risk of colectoral cancer$9,050

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamProfessor Rodney Scott, Professor Robyn Ward, Assoc. Prof Nicholas Hawkins, Professor John Attia, Conjoint Professor David Sibbritt, Professor Pablo Moscato
SchemeNear Miss Grant
RoleInvestigator
Funding Start2006
Funding Finish2006
GNoG0186073
Type Of FundingInternal
CategoryINTE
UONY

20054 grants / $166,088

Genetic polymorphisms in the native thrombolytic and thrombotic systems as risk factors for ischaemic stroke$106,488

Funding body: National Heart Foundation of Australia

Funding bodyNational Heart Foundation of Australia
Project TeamConjoint Professor Chris Levi, Professor John Attia, Professor Rodney Scott, Dr Amanda Thrift
SchemeGrant-In-Aid
RoleInvestigator
Funding Start2005
Funding Finish2005
GNoG0184034
Type Of FundingAust Competitive - Non Commonwealth
Category1NS
UONY

Prevalence and risk factors for peripheral neuropathy in newly-diagnosed type 2 diabetes$30,000

Funding body: Diabetes Australia

Funding bodyDiabetes Australia
Project TeamConjoint Professor Wayne Smith, Professor John Attia, Conjoint Associate Professor Julia Lowe, Doctor Janine Duke
SchemeResearch Grant
RoleInvestigator
Funding Start2005
Funding Finish2005
GNoG0185002
Type Of FundingAust Competitive - Non Commonwealth
Category1NS
UONY

The effect of dietary folate, environmental toxins, and genetic polymorphisms in parents and children in determining the risk of childhood acute lymphoblastic leukaemia$20,000

Funding body: Royal Australasian College of Physicians

Funding bodyRoyal Australasian College of Physicians
Project TeamProfessor John Attia, Doctor Anne Ronan
SchemeArnott Fellowship in Cancer Research
RoleLead
Funding Start2005
Funding Finish2005
GNoG0185060
Type Of FundingNot Known
CategoryUNKN
UONY

Kryos cryogenic vessel controller$9,600

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project Team
SchemeInfrastructure Grants
RoleInvestigator
Funding Start2005
Funding Finish2005
GNo
Type Of FundingNot Known
CategoryUNKN
UONY

20044 grants / $256,065

Nature, nuture and acute childhood lymphoblastic leukaemia$193,500

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project TeamProfessor Rodney Scott, Professor John Attia
SchemeProject Grant
RoleInvestigator
Funding Start2004
Funding Finish2004
GNoG0183209
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

Ambient baroque music in dementia$30,000

Funding body: Bernard Judd Foundation

Funding bodyBernard Judd Foundation
Project TeamProfessor Kichu Nair, Professor John Attia, Conjoint Professor John Marley
SchemeResearch Grant
RoleInvestigator
Funding Start2004
Funding Finish2004
GNoG0184809
Type Of FundingContract - Aust Non Government
Category3AFC
UONY

Novel genetic and environmental risk factors in atherothrombosis: The role of variation in Cox-2, tpA and PAI-1 activity$28,000

Funding body: Hunter Medical Research Institute

Funding bodyHunter Medical Research Institute
Project TeamConjoint Professor Chris Levi, Conjoint Professor David Henry, Dr Patricia McGettigan, Professor John Attia, Professor Mark Parsons, Dr Michael Seldon, Professor Rodney Scott
SchemeResearch Grant
RoleInvestigator
Funding Start2004
Funding Finish2004
GNoG0183749
Type Of FundingContract - Aust Non Government
Category3AFC
UONY

Visit of Mrs Ammarin Thakkinstain 1 March 2004 to 30 May 2004$4,565

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamProfessor John Attia
SchemeVisitor Grant
RoleLead
Funding Start2004
Funding Finish2004
GNoG0183802
Type Of FundingInternal
CategoryINTE
UONY

20031 grants / $195,000

Research Fellows in Epidemiology$195,000

Funding body: Vicent Fairfax Family Foundation

Funding bodyVicent Fairfax Family Foundation
Project TeamProfessor Julie Byles, Professor John Attia, Conjoint Professor Wayne Smith
SchemeResearch Grant
RoleInvestigator
Funding Start2003
Funding Finish2003
GNoG0182726
Type Of FundingContract - Aust Non Government
Category3AFC
UONY

20024 grants / $1,173,786

Study of health outcomes in aircraft maintenance personnel (Phase II and III)$893,786

Funding body: Commonwealth department of veterans affairs

Funding bodyCommonwealth department of veterans affairs
Project Team
SchemeTender
RoleInvestigator
Funding Start2002
Funding Finish2004
GNo
Type Of FundingOther Public Sector - Commonwealth
Category2OPC
UONY

Study of health outcomes in aircraft maintenance personnel (Phase I)$275,000

Funding body: Commonwealth department of veterans affairs

Funding bodyCommonwealth department of veterans affairs
Project Team
SchemeTender
RoleInvestigator
Funding Start2002
Funding Finish2003
GNo
Type Of FundingOther Public Sector - Commonwealth
Category2OPC
UONY

American-Heart Association/Asia Pacific Scientific Forum, Hawaii, 23-26 April 2002$2,500

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamProfessor John Attia
SchemeTravel Grant
RoleLead
Funding Start2002
Funding Finish2002
GNoG0181696
Type Of FundingInternal
CategoryINTE
UONY

World Congress of Epidemiology, Montreal, Canada 18-22 August, 2002$2,500

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamProfessor John Attia
SchemeTravel Grant
RoleLead
Funding Start2002
Funding Finish2002
GNoG0182156
Type Of FundingInternal
CategoryINTE
UONY

20012 grants / $68,600

The Genetic Origins of Childhood Cancer.$40,000

Funding body: John Hunter Children`s Hospital Research Foundation

Funding bodyJohn Hunter Children`s Hospital Research Foundation
Project TeamProfessor Rodney Scott, Professor John Attia, Doctor Frank Alvaro
SchemeResearch Grant (Defunct)
RoleInvestigator
Funding Start2001
Funding Finish2001
GNoG0181219
Type Of FundingOther Public Sector - State
Category2OPS
UONY

Development of two courses in molecular and genetic epidemiology.$28,600

Funding body: Commonwealth Department of Health & Aged Care

Funding bodyCommonwealth Department of Health & Aged Care
Project TeamProfessor John Attia, Professor Julie Byles
SchemeInnovative Projects in Relation to PHERP
RoleLead
Funding Start2001
Funding Finish2001
GNoG0180974
Type Of FundingOther Public Sector - Commonwealth
Category2OPC
UONY

20001 grants / $9,200

The effect of angiotensin-converting enzyme gene variants on survival post-myocardial infarction and on response to ACE inhibitors.$9,200

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamProfessor John Attia
SchemeEarly Career Researcher Grant
RoleLead
Funding Start2000
Funding Finish2000
GNoG0179327
Type Of FundingInternal
CategoryINTE
UONY

19981 grants / $96,480

Tea tree oil as a topical decolonisation solution for adult inpatients with Methicillin-resistant Staphylococcus Aureas$96,480

Funding body: Rural Industries Research & Development Corporation

Funding bodyRural Industries Research & Development Corporation
Project TeamProfessor John Attia, Meredith Caelli, Assoc. Prof T Riley
SchemeResearch and Development Project
RoleLead
Funding Start1998
Funding Finish1998
GNoG0177627
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY
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Research Supervision

Current Supervision

CommencedResearch Title / Program / Supervisor Type
2015Genomics and Pharmacogenomics of Stroke
General Medicine, Faculty of Health and Medicine
Co-Supervisor
2014Defining the Immune System and Preventable Mortality in Geriatric Hip Fractures
Surgery, Faculty of Health and Medicine
Co-Supervisor
2014Does Weighing During Pregnancy Prevent Excessive Gestational Weight Gain? A Mixed-Method Study
Public Health, Faculty of Health and Medicine
Co-Supervisor
2014Smoke-Free Recovery From Trauma Surgery: A Randomised Control Trial of an Online Smoking Cessation Program for Trauma Surgery Inpatients
Behavioural Science, Faculty of Health and Medicine
Co-Supervisor
2013Impact of Dietary Protein on Postprandial Blood Glucose Levels in Type 1 Diabetes Mellitus
General Medicine, Faculty of Health and Medicine
Co-Supervisor
2012Genetic and Non-Genetic Studies of Type 2 Diabetes in Three Susceptible Asian Populations: Malay, Chinese and Indian
Health, Faculty of Health and Medicine
Co-Supervisor
2012Potential Cardio-Protective Effect of Pneumococcal Vaccine
Pharmacology, Faculty of Health and Medicine
Co-Supervisor
2012The Role of Autoantibodies in the Development of Depression
Public Health, Faculty of Health and Medicine
Principal Supervisor
2012The Association of Dietary Patterns, the Related Nutritional Factors and Depression Among Older Australians
Public Health, Faculty of Health and Medicine
Principal Supervisor
2010The Role of Zinc in Chronic Disease
Public Health, Faculty of Health and Medicine
Co-Supervisor
2005Environmental Determinants of Lupus Flares
Microbiology, Faculty of Health and Medicine
Co-Supervisor

Past Supervision

YearResearch Title / Program / Supervisor Type
2015Health Determinants in Australian Communities: A Multilevel Investigation of the Influence of Personal and Contextual Characteristics
Psychiatry, Faculty of Health and Medicine
Co-Supervisor
2014Exploring the Long-Term Experience of Psychological Morbidity in Community-Dwelling Stroke Survivors
General Medicine, Faculty of Health and Medicine
Co-Supervisor
2014The Inflammation Hypothesis of Depression: Cross Sectional Associations, Temporal Relationships and the Confounds of Comorbidity
Psychiatry, Faculty of Health and Medicine
Co-Supervisor
2014The Optimal Timing of Surgical Fracture Stabilization in Trauma Patients
General Medicine, Faculty of Health and Medicine
Co-Supervisor
2014The Relationship Between Early Alzheimer's Disease, Apolipoprotein E Genotyping & Hippocampal MRI Volumes
Public Health, Faculty of Health and Medicine
Co-Supervisor
2013Suicide in Urban and Rural Australia: Determinants, Moderators and Treatment Options for Suicidal Thoughts and Behaviours
Psychiatry, Faculty of Health and Medicine
Co-Supervisor
2012Systematic Review and Network Meta-Analysis of Intravenous Ibuprofen Vs. Intravenous Indomethacin Vs. Placebo in the Management of Clinically and/or Echocardiographically Important Patent Ductus Arteriosus in Preterm Infants at Greater than 24 Hours of Life
Public Health, Faculty of Health and Medicine
Co-Supervisor
2012Factor V Leiden and Adverse Pregnancy Outcome
Public Health, Faculty of Health and Medicine
Sole Supervisor
2012The Food and Nutrient Intake and Physical Activity of Australian Aboriginal and Torres Strait Islander and Non-Indigenous Rural Children
Behavioural Science, Faculty of Health and Medicine
Co-Supervisor
2012The Study of Health Outcomes in Aircraft Maintenance Personnel: Sensory System Effects
Public Health, Faculty of Health and Medicine
Co-Supervisor
2010The Clinical Efficacy of Tea Tree Oil as an Alternative Topical Decolonisation Agent for Adult Inpatients with Meticillin-Resistant Staphylococcus Aureus
Public Health, Faculty of Health and Medicine
Sole Supervisor
2010Genetic Polymorphisms of Platelet Glycoprotein and Cyclooxygenase-2 Genes and Their Influence on Risk of Ischaemic Stroke, 90 Day Post-Stroke Outcome, and Gene-Environment Interactions
General Medicine, Faculty of Health and Medicine
Co-Supervisor
2007Clinical Epidemiology of B Natriuretic Peptides as Tests for Heart Failure in Australian General Practice
Public Health, Faculty of Health and Medicine
Co-Supervisor
2006Cardiovascular Risk Factors in Asians and Caucasians
Public Health, Faculty of Health and Medicine
Co-Supervisor
2004Meta-analysis of Molecular Association Studies
Public Health, Faculty of Health and Medicine
Principal Supervisor
2004Molecular Epidemiological Study of Childhood Cancer
Public Health, Faculty of Health and Medicine
Principal Supervisor
2003Diet, Lifestyle, and Risk Factors for Forearm Fracture in Postmenopausal Women
Public Health, Faculty of Health and Medicine
Principal Supervisor
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News

PhD Opportunity - Biomarker for early Alzheimer's disease

PhD Opportunity - Biomarker for early Alzheimer's disease

February 3, 2015

A PhD opportunity exists for someone with biological and analytic skills who would be interested in taking advantage of collected data from an NHMRC funded study focussed on a novel potential biomarker for early Alzheimer's disease under the supervision of Conjoint Associate Professor Peter Schofield and Professor John Attia.

sleep

sleep linked to diabetes

December 12, 2013

Getting less than six hours sleep each night (compared to seven hours) may increase type 2 diabetes risk by 30 per cent but has less impact on heart disease than previously thought, researchers from the University of Newcastle have found.

HMRI

New study shows genetic role in education

May 31, 2013

A multinational consortium of medical researchers and social scientists has found a link between educational attainment and tiny variations in a person's genetic sequence.

Professor John Attia

Position

Academic Director
CReDITSS Unit
School of Medicine and Public Health
Faculty of Health and Medicine

Contact Details

Emailjohn.attia@newcastle.edu.au
Phone(02) 4042 0500
Fax(02) 40420039

Office

Room3014
BuildingHunter Medical Research Institute Building
LocationKookaburra Circuit, John Hunter Hospital Campus New Lambton NSW 2305

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