Profile Image

Staff Profile

Edit

Career Summary

Biography

Jodie Simpson is a senior research fellow in The University of Newcastle’s Priority Research Centre for Asthma and Respiratory Disease and the current holder of the Australian Respiratory Council’s Ann Woolcock Research Fellowship. Her research focuses on the inflammatory biomarkers of airways disease and she has a particular interest in innate immune pathways and their role in airways disease. She has developed several important assays for the assessment of inflammatory mediators in airway secretions and continues to work on assessment of novel markers of airway inflammation. In 2005, Jodie completed her PhD where she identified and characterised four inflammatory phenotypes in asthma based on the presence of absence of increased sputum eosinophil and neutrophil proportions. This work has led to further investigations of asthma inflammatory phenotypes using gene expression profiling and recently the identification of novel biomarkers for asthma and COPD.

Dr Simpson designed and conducted the first RCT of macrolide antibiotics in severe refractory asthma, this research was pivotal in her success with a large NHMRC project grant awarded in 2008 to investigate macrolide antibiotic therapy in asthma as a multi-centre RCT (The AMAZES study). In her earlier work, Dr Simpson demonstrated that macrolide antibiotics are an effective anti-inflammatory therapy in non-eosinophilic refractory asthma. She is currently working on the AMAZES study collaborating with centres around Australia and working on 2 sub-studies, the first looking at macrophage phagocytosis and the second investigating airway and systemic inflammation in asthma subtypes.

Jodie has actively presented her work at national and international scientific meetings and has authored over 50 papers in peer reviewed journals. She is an active participant in research service and teaching as representative on TSANZ research subcommittee and the supervisor of 4 research higher degree students.

Qualifications

  • PhD (Medicine), University of Newcastle, 13/08/2005
  • Bachelor of Science, University of Newcastle, 09/05/1997
  • Bachelor of Science (Honours), University of Newcastle, 01/05/1998

Research

Research keywords

  • COPD
  • asthma
  • clinical trials
  • immune response
  • inflammation

Research expertise

Jodie Simpson is a senior research fellow in The University of Newcastle’s Priority Research Centre for Asthma and Respiratory Disease and the current holder of the Australian Respiratory Council’s Ann Woolcock Research Fellowship. Her research focuses on the inflammatory biomarkers of airways disease and she has a particular interest in innate immune pathways and their role in airways disease

Languages

  • English

Fields of Research

CodeDescriptionPercentage
110203Respiratory Diseases100

Memberships

Body relevant to professional practice.

  • American Thoracic Society
  • Thoracic Society of Australia and New Zealand

Teaching

Teaching keywords

  • asthma and COPD
  • induced sputum
  • inflammatory mediators
Edit

Highlighted Publications

For publications that are currently unpublished or in-press, details are shown in italics.

YearCitationAltmetricsLink
2007Simpson JL, Grissell TV, Douwes J, Scott R, Boyle MJ, Gibson PG, 'Innate immune activation in neutrophilic asthma and bronchiectasis', Thorax, 62 211-218 (2007) [C1]
2005Simpson JL, Scott R, Boyle MJ, Gibson PG, 'Differential proteolytic enzyme activity in eosinophilic and neutrophilic asthma', American Journal of Respiratory and Critical Care Medicine, 172 559-565 (2005) [C1]
2006Simpson JL, Scott R, Boyle MJ, Gibson PG, 'Inflammatory subtypes in asthma: Assessment and identification using induced sputum', Respirology, 11 54-61 (2006) [C1]
2005Simpson JL, Wood LG, Gibson PG, 'Inflammatory mediators in exhaled breath, induced sputum and saliva', Clinical & Experimental Allergy, 35 1180-1185 (2005) [C1]

Publications

For publications that are currently unpublished or in-press, details are shown in italics.

Click on a category title below to expand the list of citations for that specific category.

Chapter (1 outputs)

YearCitationAltmetricsLink
2009Simpson JL, Baines KJ, Gibson PG, 'Biology of neutrophils', Middleton's Allergy: Principles & Practice, Mosby, Philadelphia, Pennsylvania 283-294 (2009) [B1]

Journal article (77 outputs)

YearCitationAltmetricsLink
2014Simpson JL, Gibson PG, Yang IA, Upham J, James A, Reynolds PN, Hodge S, 'Altered sputum granzyme B and granzyme B/proteinase inhibitor-9 in patients with non-eosinophilic asthma', RESPIROLOGY, 19 280-287 (2014) [C1]
2014Gibson PG, Simpson JL, Ryan NM, Vertigan AE, 'Mechanisms of cough', CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY, 14 55-61 (2014) [C1]
2014Gunawardhana LP, Gibson PG, Simpson JL, Powell H, Baines KJ, 'Activity and expression of histone acetylases and deacetylases in inflammatory phenotypes of asthma', CLINICAL AND EXPERIMENTAL ALLERGY, 44 47-57 (2014) [C1]
2014Zhang X-Y, Simpson JL, Powell H, Yang IA, Upham JW, Reynolds PN, et al., 'Full blood count parameters for the detection of asthma inflammatory phenotypes', Clinical and Experimental Allergy, 44 1137-1145 (2014)
2014Fu J-J, McDonald VM, Gibson PG, Simpson JL, 'Systemic inflammation in older adults with asthma-COPD overlap syndrome', Allergy, Asthma and Immunology Research, 6 316-324 (2014)
2014Simpson JL, Powell H, Baines KJ, Milne D, Coxson HO, Hansbro PM, Gibson PG, 'The effect of azithromycin in adults with stable neutrophilic COPD: a double blind randomised, placebo controlled trial.', PLoS One, 9 e105609 (2014)
2014Simpson JL, Phipps S, Baines KJ, Oreo KM, Gunawardhana L, Gibson PG, 'Elevated expression of the NLRP3 inflammasome in neutrophilic asthma', European Respiratory Journal, 43 1067-1076 (2014)
2014Oreo KM, Gibson PG, Simpson JL, Wood LG, McDonald VM, Baines KJ, 'Sputum ADAM8 expression is increased in severe asthma and COPD', CLINICAL AND EXPERIMENTAL ALLERGY, 44 342-352 (2014)
2014Baines KJ, Upham JW, Yerkovich ST, Chang AB, Marchant JM, Carroll M, et al., 'Mediators of neutrophil function in children with protracted bacterial bronchitis', Chest, 146 1013-1020 (2014)
2014Baines KJ, Simpson JL, Wood LG, Fibbens NL, Powell H, Gibson PG, et al., 'Sputum gene expression signature of 6 biomarkers discriminates asthma inflammatory phenotypes', Journal of Allergy and Clinical Immunology, (2014)
2014Simpson J, Carroll M, Gibson P, Yang I, Reynolds P, Hodge S, et al., 'REDUCED ANTI-VIRAL INNATE IMMUNITY IN PATIENTS WITH SEVERE ASTHMA IS ASSOCIATED WITH NEUTROPHILIC INFLAMMATION AND HIGH DOSE INHALED STEROIDS', RESPIROLOGY, 19 81-81 (2014)
2014Gunawardhana LP, Baines KJ, Mattes J, Murphy VE, Simpson JL, Gibson PG, 'Differential DNA methylation profiles of infants exposed to maternal asthma during pregnancy.', Pediatr Pulmonol, 49 852-862 (2014)
2014Fu J-J, Gibson PG, Simpson JL, McDonald VM, 'Longitudinal changes in clinical outcomes in older patients with asthma, COPD and asthma-COPD overlap syndrome', Respiration, 87 63-74 (2014)
2014Baines K, Simpson J, Wood L, Scott R, Fibbens N, Powell H, et al., 'SPUTUM GENE EXPRESSION OF SIX MARKERS IDENTIFIES ASTHMA INFLAMMATORY PHENOTYPE AND CORTICOSTEROID RESPONSE', RESPIROLOGY, 19 37-37 (2014)
2014Simpson JL, Baines KJ, Ryan N, Gibson PG, 'Neutrophilic asthma is characterised by increased rhinosinusitis with sleep disturbance and GERD.', Asian Pac J Allergy Immunol, 32 66-74 (2014)
2014Gunawardhana LP, Gibson PG, Simpson JL, Benton MC, Lea RA, Baines KJ, 'Characteristic DNA methylation profiles in peripheral blood monocytes are associated with inflammatory phenotypes of asthma.', Epigenetics, 9 1302-1316 (2014)
2013Mcdonald VM, Simpson JL, Mcelduff P, Gibson PG, 'Older peoples' perception of tests used in the assessment and management of COPD and asthma', Clinical Respiratory Journal, 7 367-374 (2013) [C1]
2013Simpson JL, McDonald VM, Baines KJ, Oreo KM, Wang F, Hansbro PM, Gibson PG, 'Influence of Age, Past Smoking, and Disease Severity on TLR2, Neutrophilic Inflammation, and MMP-9 Levels in COPD', MEDIATORS OF INFLAMMATION, (2013) [C1]
2013Kaiko GE, Loh Z, Spann K, Lynch JP, Lalwani A, Zheng Z, et al., 'Toll-like receptor 7 gene deficiency and early-life Pneumovirus infection interact to predispose toward the development of asthma-like pathology in mice', JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 131 1331-U132 (2013) [C1]
2013Gao P, Simpson JL, Zhang J, Gibson PG, 'Galectin-3: its role in asthma and potential as an anti-inflammatory target', RESPIRATORY RESEARCH, 14 (2013) [C1]
2013Brooks CR, Gibson PG, Douwes J, Van Dalen CJ, Simpson JL, 'Relationship between airway neutrophilia and ageing in asthmatics and non-asthmatics', RESPIROLOGY, 18 857-865 (2013) [C1]
2013Simpson JL, Gibson PG, Yang IA, Upham J, James A, Reynolds PN, Hodge S, 'Impaired macrophage phagocytosis in non-eosinophilic asthma', CLINICAL AND EXPERIMENTAL ALLERGY, 43 29-35 (2013) [C1]
2012Sukkar MB, Wood LG, Tooze MK, Simpson JL, McDonald VM, Gibson PG, Wark PA, 'Soluble RAGE is deficient in neutrophilic asthma and COPD', European Respiratory Journal, 39 721-729 (2012) [C1]
2012Essilfie A-T, Simpson JL, Dunkley ML, Morgan LC, Oliver BG, Gibson PG, et al., 'Combined haemophilus influenzae respiratory infection and allergic airways disease drives chronic infection and features of neutrophilic asthma', Thorax, 67 588-599 (2012) [C1]
2012Simpson JL, Phipps S, Baines KJ, Oreo KM, Gibson PG, 'NALP3 INFLAMMASOME ACTIVATION IN NEUTROPHILIC ASTHMA', RESPIROLOGY, 17 2-2 (2012) [E3]
2011Baines KJ, Simpson JL, Wood LG, Scott R, Gibson PG, 'Systemic upregulation of neutrophil a-defensins and serine proteases in neutrophilic asthma', Thorax, 66 942-947 (2011) [C1]
2011McDonald VM, Simpson JL, Higgins IJ, Gibson PG, 'Multidimensional assessment of older people with asthma and COPD: Clinical management and health status', Age and Ageing, 40 42-49 (2011) [C1]
2011McDonald VM, Higgins IJ, Simpson JL, Gibson PG, 'The importance of clinical management problems in older people with COPD and asthma: Do patients and physicians agree?', Primary Care Respiratory Journal, 20 389-395 (2011) [C1]
2011Baines KJ, Simpson JL, Wood LG, Scott R, Gibson PG, 'Transcriptional phenotypes of asthma defined by gene expression profiling of induced sputum samples', Journal of Allergy and Clinical Immunology, 127 153.e9-160.e9 (2011) [C1]
2011Baines KJ, Simpson JL, Gibson PG, 'Innate immune responses are increased in chronic obstructive pulmonary disease', PLoS ONE, 36 e18426 (2011) [C1]
2011Wang F, He XY, Baines KJ, Gunawardhana LP, Simpson JL, Li F, Gibson PG, 'Different inflammatory phenotypes in adults and children with acute asthma', European Respiratory Journal, 38 567-574 (2011) [C1]
2011Verrills NM, Irwin JA, He XY, Wood LG, Powell H, Simpson JL, et al., 'Identification of novel diagnostic biomarkers for asthma and chronic obstructive pulmonary disease', American Journal of Respiratory and Critical Care Medicine, 183 1633-1643 (2011) [C1]
2011Wood LG, Simpson JL, Wark PA, Powell H, Gibson PG, 'Characterization of innate immune signalling receptors in virus-induced acute asthma', Clinical and Experimental Allergy, 41 640-648 (2011) [C1]
2011Essilfie A-T, Simpson JL, Horvat JC, Preston JA, Dunkley ML, Foster PS, et al., 'Haemophilus influenzae infection drives IL-17-mediated neutrophilic allergic airways disease', PLoS Pathogens, 7 e1002244 (2011) [C1]
2011He XY, Simpson JL, Wang F, 'Inflammatory phenotypes in stable and acute childhood asthma', Paediatric Respiratory Reviews, 12 165-169 (2011) [C1]
2010Wood LG, Simpson JL, Hansbro PM, Gibson PG, 'Potentially pathogenic bacteria cultured from the sputum of stable asthmatics are associated with increased 8-isoprostane and airway neutrophilia', Free Radical Research, 44 146-154 (2010) [C1]
2010Baines KJ, Simpson JL, Bowden NA, Scott R, Gibson PG, 'Differential gene expression and cytokine production from neutrophils in asthma phenotypes', European Respiratory Journal, 35 522-531 (2010) [C1]
2009Gibson PG, Simpson JL, 'The overlap syndrome of asthma and COPD: What are its features and how important is it?', Thorax, 64 728-735 (2009) [C1]
2009Baines KJ, Simpson JL, Scott R, Gibson PG, 'Immune responses of airway neutrophils are impaired in asthma', Experimental Lung Research, 35 554-569 (2009) [C1]
2009Simpson JL, Baines KJ, Boyle MJ, Scott R, Gibson PG, 'Oncostatin M (OSM) is increased in asthma with incompletely reversible airflow obstruction', Experimental Lung Research, 35 781-794 (2009) [C1]
2009Simpson JL, Milne DG, Gibson PG, 'Neutrophilic asthma has different radiographic features to COPD and smokers', Respiratory Medicine, 103 881-887 (2009) [C1]
2009Simpson JL, Phipps S, Gibson PG, 'Inflammatory mechanisms and treatment of obstructive airway diseases with neutrophilic bronchitis', Pharmacology and Therapeutics, 124 86-95 (2009) [C1]
2009Simpson JL, McElduff P, Gibson PG, 'Assessment and reproducibility of non-eosinophilic asthma using induced sputum', Respiration, 79 147-151 (2009) [C1]
2008Simpson JL, Brooks C, Douwes J, 'Innate immunity in asthma', Paediatric Respiratory Reviews, 9 263-270 (2008) [C1]
2008Simpson JL, Wark PA, 'The role of exhaled nitric oxide and exhaled breath condensates in evaluating airway inflammation in asthma', Expert Opinion on Medical Diagnostics, 2 607-620 (2008) [C1]
2008Wood LG, Garg ML, Blake RJ, Simpson JL, Gibson PG, 'Oxidized vitamin E and glutathione as markers of clinical status in asthma', Clinical Nutrition, 27 579-586 (2008) [C1]
2008Simpson JL, Powell H, Boyle MJ, Scott R, Gibson PG, 'Clarithromycin targets neutrophilic airway inflammation in refractory asthma', American Journal of Respiratory and Critical Care Medicine, 177 148-155 (2008) [C1]
2007Yang Z, Yan WX, Cai H, Tedla N, Armishaw C, Di Girolamo N, et al., 'S100A12 provokes mast cell activation: A potential amplification pathway in asthma and innate immunity', Journal of Allergy and Clinical Immunology, 119 106-114 (2007) [C1]
2007Weckmann M, Collison A, Simpson JL, Kopp MV, Wark PA, Smyth MJ, et al., 'Critical link between TRAIL and CCL20 for the activation of T(H)2 cells and the expression of allergic airway disease', Nature Medicine, 13 1308-1315 (2007) [C1]
2007Simpson JL, Grissell TV, Douwes J, Scott R, Boyle MJ, Gibson PG, 'Innate immune activation in neutrophilic asthma and bronchiectasis', Thorax, 62 211-218 (2007) [C1]
2006Simpson JL, Scott R, Boyle MJ, Gibson PG, 'Inflammatory subtypes in asthma: Assessment and identification using induced sputum', Respirology, 11 54-61 (2006) [C1]
2005Simpson JL, Scott R, Boyle MJ, Gibson PG, 'Differential proteolytic enzyme activity in eosinophilic and neutrophilic asthma', American Journal of Respiratory and Critical Care Medicine, 172 559-565 (2005) [C1]
2005Wood LG, Garg ML, Simpson JL, Mori TA, Croft KD, Wark PA, Gibson PG, 'Induced sputum 8-isoprostane concentrations in inflammatory airway diseases', American Journal of Respiratory and Critical Care Medicine, 171 426-430 (2005) [C1]
2005Simpson JL, Wood LG, Gibson PG, 'Inflammatory mediators in exhaled breath, induced sputum and saliva', Clinical & Experimental Allergy, 35 1180-1185 (2005) [C1]
2005Simpson JL, Gibson PG, 'Deficient Sputum Anti-Protease Defenses in Neutrophilic and Eosinophilic Asthma', INFLAMMATION RESEARCH, 54 S136-S137 (2005)
2005Bains KJ, Bell NV, Simpson JL, Scott RJ, Boyle MJ, Gibson PG, 'Enhanced IL-8 Release front Neutrophils in Non-Eosinophilic Asthma', INFLAMMATION RESEARCH, 54 S137-S137 (2005)
2004Gibson PG, Simpson JL, 'The European Network For Understanding Mechanisms Of Severe Asthma study', European Respiratory Journal, 23 492-495 (2004) [C1]
2004Simpson JL, Timmins N, Fakes K, Talbot P, Gibson PG, 'Effect of saliva contamination on induced sputum cell counts, IL-8 and eosinophil cationic protein levels', European Respiratory Journal, 23 759-762 (2004) [C1]
2004Gibson PG, Simpson JL, Holgate ST, Dahlén S-E, Reid DW, Champion A, et al., ' The European Network For Understanding Mechanisms Of Severe Asthma study; Host response to transmissible Pseudomonas aeruginosa; The use of computer-animation programs during spirometry in preschool children', European Respiratory Journal, 23 492-495 (2004)
2003Gibson PG, Wark PA, Simpson JL, Meldrum CJ, Meldrum S, Saltos N, Boyle MJ, 'Induced sputum IL-8 gene expression, neutrophil influx and MMP-9 in allergic bronchopulmonary aspergillosis', European Respiratory Journal, 21 582-588 (2003) [C1]
2003Wark PA, Hensley MJ, Saltos N, Boyle MJ, Toneguzzi R, Simpson JL, et al., 'Anti-inflammatory effect of itraconazole in stable allergic bronchopulmonary aspergillosis: A randomized controlled trial', The Journal of Allergy and Clinical Immunology, 111 952-957 (2003) [C1]
2003Gibson PG, Simpson JL, Hankin RG, Powell HG, Henry RL, 'Relationship between included sputum eosinophils and clinical pattern of childhood asthma', Thorax, 58 116-121 (2003) [C1]
2003Simpson JL, Moric I, Wark PA, Johnston S, Gibson PG, 'Use of induced sputum for the diagnosis of influenza and infections in asthma: a comparison of diagnostic techniques', Journal of Clinical Virology, 339-346 (2003) [C1]
2002Chang A, Harrhy V, Simpson JL, Masters I, Gibson PG, 'Cough, airway inflammation, and mild asthma exacerbation', Archives of Disease in Childhood, 86 270-275 (2002) [C1]

Co-authors: Peter Gibson

2002Wark PA, Johnston S, Simpson JL, Hensley MJ, Gibson PG, 'Chlamydia pneumoniae immunoglobulin A reactivation and airway inflammation in acute asthma', The European Respiratory Journal, 20 834-840 (2002) [C1]
2002Simpson JL, Gibson PG, Wark PA, 'Optimization of sputum-processing methods for the measurement of interleukin-5: Effects of protease inhibition', Respirology, 7 111-116 (2002) [C1]
2002Wark PA, Johnston S, Moric I, Simpson JL, Hensley MJ, Gibson PG, 'Neutrophil degranulation and cell lysis is associated with clinical severity in virus-induced asthma', The European Respiratory Journal, 19 68-75 (2002) [C1]
2002Wark PA, Simpson JL, Hensley MJ, Gibson PG, 'Airway inflammation in thunderstorm asthma', Clinical and Experimental Allergy, 32 1750-1756 (2002) [C1]
2001Jones PD, Hankin RG, Simpson J, Gibson PG, Henry R, 'The Tolerability, Safety, and Success of Sputum Induction and Combined Hypertonic Saline Challenge in Children', American Journal of Respiratory And Critical Care Medicine, 164 1146-1149 (2001) [C1]

Co-authors: Peter Gibson

2001Gibson PG, Simpson J, Saltos N, 'Heterogeneity of Airway Inflammation in Persistant Asthma Evidence of Neturophilic Inflammation and Increased Sputum Interleukin-8', Chest, 119 1329-1336 (2001) [C1]

Co-authors: Peter Gibson

2001Gibson PG, Simpson J, Chalmers AC, Toneguzzi R, Wark PA, Wilson AJ, Hensley MJ, 'Airway Eosinophilia is associated with Wheeze but is uncommon in Children with Persistent Cough and Frequent Chest Colds', American Journal of Respiratory and Critical Care Medicine, 164 977-981 (2001) [C1]
2001Wark PA, Simpson J, Hensley MJ, Gibson PG, 'Safety of sputum induction with isotonic saline in adults with acute severe asthma', Clinical and Experimental Allergy, 31 1745-1753 (2001) [C1]
2001Wark P, Simpson JL, Saltos N, Hensley MJ, Gibson PC, 'Itraconazole reduces eosinophilic airway inflammation in allergic bronchopulmonary aspergillosis (abpa)', Respirology, 6 (2001)
2001Pab W, Simpson JL, 'Airway inflammation in acute asthma following a thunderstorm is associated with increased sputl'm eosinophilia and eosinophil degranulation', Respirology, 6 (2001)
2000Wark PA, Saltos N, Simpson J, Slater S, Hensley MJ, Gibson PG, 'Induced sputum easinophils and neutrophils and bronchiectasis severity in allergic bronchopulmonary aspergillosis', European Respiratory Journal, 16 1095-1101 (2000) [C1]
2000Norzila M, Fakes K, Henry R, Simpson J, Gibson PG, 'Interleukin-8 secretion and neutrophil recruitment accompanies induced sputum eosinophil activation in children with acute asthma', American Journal of respiratory and Critical Care Medicine, 161 769-774 (2000) [C1]

Co-authors: Peter Gibson

1999Gibson PG, Norzila MZ, Fakes K, Simpson J, Henry RL, 'Pattern of airway inflammation and its determinants in children with acute severe asthma', PEDIATRIC PULMONOLOGY, 28 261-270 (1999)
Show 74 more

Conference (81 outputs)

YearCitationAltmetricsLink
2014Wright T, Gibson P, Simpson J, Mcdonald V, Wood L, Baines K, 'ALARMINS IN ASTHMA AND COPD: RELATIONSHIPS TO INFLAMMATORY PHENOTYPES AND DISEASE SEVERITY', RESPIROLOGY (2014) [E3]
2014Upham JW, Carroll M, Gibson P, Yang IA, Simpson J, 'Anti-Viral Innate Immunity Varies Across Different Asthma Inflammatory Phenotypes', JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, San Diego, CA (2014) [E3]
2014Eckert B, Simpson J, Powell H, Pretto J, Upham J, Gibson P, 'EXHALED NITRIC OXIDE MEASUREMENT: INTER-INSTRUMENT VARIABILITY AND IMPLICATIONS ON TESTS INTERPRETATION', RESPIROLOGY (2014) [E3]
2014Eckert B, Simpson J, Powell H, Pretto J, Upham J, Gibson P, 'EXHALED NITRIC OXIDE MEASUREMENT: INTER-INSTRUMENT VARIABILITY AND IMPLICATIONS ON TEST INTERPRETATION', RESPIROLOGY (2014)
2014Simpson J, Gao P, Baines K, Yang I, Reynolds P, Hodge S, et al., 'GALECTIN 3 AND GALECTIN 3 BINDING PROTEIN IN ASTHMA INFLAMMATORY SUBTYPES', RESPIROLOGY (2014)
2014Baines K, Upham J, Yerkovich S, Chang A, Marchant J, Carroll M, et al., 'INTERLEUKIN-1B IS RELATED TO CLINICAL OUTCOMES IN PROTRACTED BACTERIAL BRONCHITIS', RESPIROLOGY (2014)
2013Zhong H, Simpson JL, Wood LG, Wark PAB, 'COPD PERIPHERAL BLOOD NEUTROPHILS HAVE ENHANCED RELEASE OF IL-1B WHEN STIMULATED', RESPIROLOGY (2013) [E3]
2013Fu JJ, Mcdonald VM, Simpson JL, Higgins I, Mao B, Gibson PG, 'VALIDATION OF THE NEW GOLD COMBINED ASSESSMENT IN AN AUSTRALIAN COPD COHORT', RESPIROLOGY (2013) [E3]
2013Thasneem A, Simpson JL, Pradeepan S, 'OVERLAP SYNDROME-PREVALENCE, CHARACTERISTICS AND PREDICTORS', RESPIROLOGY (2013) [E3]
2013Simpson JL, Baines KJ, Ryan NM, Gibson PG, 'NEUTROPHILIC ASTHMA IS CHARACTERIZED BY INCREASED GERD AND RHINOSINUSITIS WITH SLEEP DISTURBANCE', RESPIROLOGY (2013) [E3]
2013Simpson JL, Yang IA, Reynolds PN, Hodge SJ, James AL, Upham J, et al., 'ALTERNATIVES TO INDUCED SPUTUM FOR IDENTIFYING PATIENTS WITH EOSINOPHILIC ASTHMA', RESPIROLOGY (2013) [E3]
2013Baines KJ, Simpson JL, Mcdonald VM, Hsu AC, Gibson PG, 'DIFFERENTIAL AIRWAY GENE EXPRESSION IN COPD', RESPIROLOGY (2013) [E3]
2013Gunawardhana LP, Baines KJ, Mattes J, Murphy VE, Simpson JL, Gibson PG, 'EPIGENETIC ALTERATIONS IN INFANTS ASSOCIATED WITH MATERNAL ASTHMA DURING PREGNANCY', RESPIROLOGY (2013) [E3]
2013Powell H, Garside CG, Simpson JL, Yang IA, Reynolds PN, Hodge SJ, et al., 'CHARACTERISTICS OF UNCONTROLLED ASTHMA IN AUSTRALIA', RESPIROLOGY (2013) [E3]
2012Baines KJ, Simpson JL, Wood LG, Scott RJ, Gibson PG, 'Sputum gene expression of mast cell specific proteases are increased in eosinophilic asthma', Respirology, Canberra, ACT (2012) [E3]
2012Zhong H, Simpson JL, Wood LG, Wark PA, 'Different responses of blood neutrophils from COPD', Respirology, Hong Kong (2012) [E3]

Co-authors: Lisa Wood, Peter Wark

2012McDonald VM, Fu J, Simpson JL, Gibson PG, 'The longitudinal determinants of decline in obstructive airway diseases', Respirology, Canberra, ACT (2012) [E3]
2012Brooks CR, Gibson PG, Douwes J, Van Dalen CJ, Simpson JL, 'Assessment of the relationship between airway neutrophilia and aging in asthmatics and non-asthmatics', Respirology, Hong Kong (2012) [E3]

Co-authors: Peter Gibson

2012See HV, Simpson JL, Hansbro PM, Wark PA, 'Stable COPD patients have less rhinovirus-induced intracellular innate cytokines detected in PBMCS compared to healthy adults', Respirology, Canberra, ACT (2012) [E3]
2012Zhong H, Simpson JL, Wood LG, Wark PA, 'Activation of human neutrophils exposed to cigarette smoke extract: A comparison of COPD patients versus healthy non-smokers', Respirology, Canberra, ACT (2012) [E3]

Co-authors: Lisa Wood, Peter Wark

2012Fu J, McDonald VM, Gibson PG, Simpson JL, 'Systemic inflammation in older adults with asthma-COPD overlap syndrome', Abstracts. European Respiratory Society Annual Congress 2012, Vienna (2012) [E3]
2012Baines KJ, Simpson JL, Wood LG, Scott RJ, Gibson PG, 'Induced sputum differential gene expression implicates increased p38 signalling activity in severe asthma', Respirology, Canberra, ACT (2012) [E3]
2012Garside CG, Simpson JL, Yang IA, Reynolds PN, Hodge SJ, James AL, et al., 'Inflammatory subtypes of uncontrolled asthma in Australia', Respirology, Canberra, ACT (2012) [E3]

Co-authors: Peter Gibson

2012Simpson JL, Phipps S, Baines KJ, Oreo K, Gibson PG, 'NALP3 inflammasome activation in neutrophilic asthma', Respirology, Canberra, ACT (2012) [E3]
2011Baines KJ, Simpson JL, Scott R, Wood LG, Gibson PG, 'Systemic upregulation of neutrophil a-defensins and serine proteases in neutrophilic asthma', European Respiratory Society Annual Congress 2011 Abstracts, Amsterdam (2011) [E3]
2011See HV, Simpson JL, Hansbro PM, Wark PA, 'COPD patients PBMCS have an impaired immune response to phinovirus-infected bronchial epithelium', Respirology, Perth, WA (2011) [E3]
2011Horvat JC, Essilfie A-T, Kim RY, Simpson JL, Dunkley ML, Beagley KW, et al., 'Investigation of infection-induced steroid resistant asthma', Respirology, Perth, WA (2011) [E3]
2011Gunawardhana LP, Baines KJ, Simpson JL, Mattes J, Murphy VE, Gibson PG, 'Maternal asthma is associated with alterations in DNA methylation profile of peripheral blood of infants', Respirology, Perth, WA (2011) [E3]
2011Sukkar MB, Wood LG, Tooze MK, Simpson JL, McDonald VM, Gibson PG, Wark PA, 'Deficiency of srage in asthma and COPD is selectively associated with neutrophilic airway inflammation', American Journal of Respiratory and Critical Care Medicine, Denver, CO (2011) [E3]
2011Baines KJ, Simpson JL, Scott R, Wood LG, Gibson PG, 'Sputum gene expression of mast cell tryptase and carboxypeptidase A3 are increased in eosinophilic asthma', European Respiratory Society Annual Congress 2011 Abstracts, Amsterdam (2011) [E3]
2011Baines KJ, Simpson JL, Scott R, Wood LG, Gibson PG, 'Analysis of systemic gene expression according to inflammatory phenotype of asthma', Respirology, Perth, WA (2011) [E3]
2011McDonald VM, Simpson JL, Higgins IJ, Gibson PG, 'Mucus hypersecretion and chronic bronchitis in older adults with chronic obstructive airway diseases', Respirology, Shanghai (2011) [E3]
2011Hansbro PM, Horvat JC, Essilfie A-T, Kim RY, Simpson JL, Dunkley ML, et al., 'Infection-induced neutrophilic allergic airways disease is resistant to steroid treatment', American Journal of Respiratory and Critical Care Medicine, Denver, CO (2011) [E3]
2011Sukkar M, Wood LG, Tooze MK, Simpson JL, McDonald VM, Gibson PG, Wark PA, 'Soluble RAGE is deficient in neutrophilic asthma and COPD', Respirology, Perth, WA (2011) [E3]
2011Hodge S, Richard S, Simpson JL, Garside CG, Herewane K, Yang I, et al., 'Granzyme B is increased in induced sputum both from patients with COPD and non-eosinophilic asthma', Respirology, Perth, WA (2011) [E3]

Co-authors: Peter Gibson

2011Baines KJ, Simpson JL, Scott R, Wood LG, Gibson PG, 'Induced sputum differential gene expression implicates increased p38 signalling activity in severe asthma', European Respiratory Society Annual Congress 2011 Abstracts, Amsterdam (2011) [E3]
2011Zhong H, Tooze MK, Wood LG, Simpson JL, Wark PA, 'Effect of cigarette smoke extract on neutrophils isolated from human peripheral blood', Respirology, Perth, WA (2011) [E3]

Co-authors: Lisa Wood, Peter Wark

2011Hodge S, Simpson JL, Richard S, Garside CG, Yang I, Upham J, et al., 'Non-eosinophilic asthma resembles COPD with suppressed apoptotic cell clearance and macrophage recognition molecules', Respirology, Perth, WA (2011) [E3]

Co-authors: Peter Gibson

2011Wang F, Xy HA, Baines KJ, Gunawardhana LP, Simpson JL, Ki F, Gibson PG, 'Is chalamydophyla a pneumoniae infection related to non-eosinophilic asthma?', Respirology, Perth, WA (2011) [E3]
2011Garside CG, Simpson JL, Yang IA, James AL, Upham JW, Reynolds PN, et al., 'Characterizing the severe asthma phenotype in an Australian setting: The Amazes Study', Respirology, Perth, WA (2011) [E3]

Co-authors: Peter Gibson

2010Simpson JL, McDonald VM, Gibson PG, 'The relationship between systemic inflammation, airway inflammation and airway obstruction in COPD', Respirology, Brisbane, QLD (2010) [E3]
2010Simpson JL, McDonald VM, Gibson PG, 'Exhaled nitric oxide is not a marker of eosinophilic inflammation in older Australians', Respirology, Brisbane, QLD (2010) [E3]
2010McDonald VM, Simpson JL, Higgins IJ, Gibson PG, 'Is there an association between self reported acitivity limitation and exercise tolerance in COPD?', Respirology, Brisbane, QLD (2010) [E3]
2010McDonald VM, Higgins IJ, Simpson JL, Gibson PG, 'Is there an association between self reported activity limitation and exercise tolerance in COPD?', European Respiratory Society Annual Congress 2010. Abstracts, Barcelona, Spain (2010) [E3]
2010Baines KJ, Simpson JL, Scott RJ, Wood LG, Gibson PG, 'Molecular profiling of asthma defined by gene expression', Respirology, Brisbane, QLD (2010) [E3]
2010Baines KJ, Simpson JL, Scott R, Wood LG, Gibson PG, 'Molecular phenotypes of asthma defined by gene expression profiling', Respirology, Brisbane, QLD (2010) [E3]
2010Baines KJ, Simpson JL, Scott R, Wood LG, Gibson PG, 'Molecular phenotypes of asthma defined by gene expression profiling', American Journal of Respiratory and Critical Care Medicine, New Orleans, LO (2010) [E3]
2010Hansbro PM, Essilfie A-T, Simpson JL, Dunkley ML, Horvat JC, Gibson PG, Foster PS, 'Haemophilus influenzae induces IL-17-mediated neutrophilic allergic airways disease', American Journal of Respiratory and Critical Care Medicine, New Orleans (2010) [E3]
2010McDonald VM, Higgins IJ, Simpson JL, Gibson PG, 'Six minute walk tests: Are practice tests necessary?', European Respiratory Society Annual Congress 2010. Abstracts, Barcelona, Spain (2010) [E3]
2010Baines KJ, Simpson JL, Scott R, Wood LG, Gibson PG, 'Analysis of systemic gene expression according to inflammatory phenotype of asthma', Biomarker Discovery Conference, Shoal Bay, NSW (2010) [E3]
2009Baines KJ, Simpson JL, Scott R, Wood LG, Gibson PG, 'Genome wide gene expression of induced sputum in non-eosinophilic asthma', AMATA 2009, Katoomba, NSW (2009) [E3]
2009Oreo K, Baines KJ, Gibson PG, Hansbro PM, Simpson JL, 'Toll-like receptor agonists stimulate cytokine release from blood but not airway cells', Respirology, Darwin, NT (2009) [E3]
2009Simpson JL, Gibson PG, Reynolds PN, Hodge S, 'Impaired macrophage phagocytosis in non-eosinophilic asthma', Respirology, Darwin, NT (2009) [E3]
2009Wark PA, See HV, Simpson JL, Vanders RL, Hansbro PM, 'Peripheral blood monocytes (PBMCs) display innate antiviral response to rhinovirus (RV) infected bronchial epithelial cells', Journal of Immunology, Seattle, WASH. (2009) [E3]
2009Essilfie A-T, Simpson JL, Dunkley ML, Foster PS, Gibson PG, Hansbro PM, 'Haemophilus influenzae infection induces features of neutrophilic asthma', Respirology, Darwin, NT (2009) [E3]
2009Oldham RA, Simpson JL, Hansbro PM, Gibson PG, 'Increased bacterial load and colonisation in COPD', Respirology, Darwin, NT (2009) [E3]
2009McDonald VM, McElduff P, Simpson JL, Higgins IJ, Gibson PG, 'Multidimensional problem assessment of asthma and COPD in an older population: Patient-physician concordance', European Respiratory Journal, Vienna, Austria (2009) [E3]
2009McDonald VM, McElduff P, Simpson JL, Higgins IJ, Gibson PG, 'Multidimensional clinical problem assessment in asthma and COPD: Patient-physician concordance', Respirology, Darwin, NT (2009) [E3]
2009Wark PA, Oldham RA, Brooks C, Simpson JL, Douwes J, 'Airway neutrophilia in chronic obstructive pulmonary disease (COPD) and asthma are associated with lower lung function and the presence of pathogenic bacteria', Respirology, Darwin, NT (2009) [E3]
2008Wark PA, Oldham RA, Simpson JL, Douwes J, 'Endotoxin levels are higher in the bronchoalveolar lavage of ex-smokers compared to never smokers', Respirology, Melbourne, VIC (2008) [E3]
2008Baines KJ, Simpson JL, Scott R, Gibson PG, 'Innate immune responses of airway neutrophils are impaired in neutrophilic asthma', Respirology, Melbourne, VIC (2008) [E3]
2008Hansbro PM, Essilfie A-T, Simpson JL, Dunkley ML, Gibson PG, Foster PS, 'Haemophilus influenzae (HI) infection induces features of neutrophilic asthma', Australasian Society for Immunology 38th Annual Scientific Meeting: Delegate Book, Canberra, ACT (2008) [E3]
2008Simpson JL, Hansbro PM, McDonald VM, Gibson PG, 'Age and disease related changes in airway inflammation and inflammatory subtype in older people with COPD', American Journal of Respiratory and Critical Care Medicine, Toronto, ONT (2008) [E3]
2008Essilfie A-T, Preston JA, Horvat JC, Dunkley ML, Foster PS, Gibson PG, et al., 'Haemophilus influenzae (Hi) infection in asthma may drive the development of neutrophilic asthma (NA)', Respirology, Melbourne, VIC (2008) [E3]
2008McDonald VM, Simpson JL, Higgins IJ, Gibson PG, 'A problem based assessment of asthma and COPD in an older population', Respirology, Melbourne, VIC (2008) [E3]
2008Simpson JL, Hansbro PM, McDonald VM, Gibson PG, 'Age and disease related changes in airway inflammation in older people with COPD', Respirology, Melbourne, VIC (2008) [E3]
2008Baines KJ, Simpson JL, Scott R, Gibson PG, 'Ageing alters airway and circulating neutrophil function', Respirology, Melbourne, VIC (2008) [E3]
2007Baines KJ, Bowden NA, Scott R, Simpson JL, Gibson PG, 'Molecular analysis of neutrophils in asthma subtypes', Respirology (TSANZ Abstracts-Posters), Auckland (2007) [E3]
2007Simpson JL, Hansbro PM, Kenyon ME, Gibson PG, 'Remodelled asthma in the elderly: is asthma turning into COPD?', Respirology (TSANZ Abstracts-Posters), Auckland (2007) [E3]
2007Simpson JL, Powell H, Boyle MJ, Scott R, Gibson PG, 'Anti-inflammatory effects of clarithromycin in refractory non-eosinophilic asthma', Respirology (TSANZ Abstracts-Posters), Auckland (2007) [E3]
2007McDonald VM, Simpson JL, Higgins IJ, Gibson PG, 'A problem based assessment of obstructive airways disease (OAD) in an elderly population', European Respiratory Society Annual Congress 2007. Abstracts, Stockholm (2007) [E3]
2007Essiflie A, Preston JA, Horvat JC, Dunkley ML, Foster PS, Gibson PG, et al., 'Elucidating the association between Haemophilus influenzae infection and neutrophilic allergic airways disease using mouse models', Immuno 2007: 13th International Congress of Immunology. Abstracts and Posters, Rio de Janeiro, Brazil (2007) [E3]
2007Simpson JL, Milne DG, Gibson PG, 'Radiographic differences between neutrophilic asthma, COPD and smokers using HRCT', Respirology (TSANZ Abstracts-Posters), Auckland (2007) [E3]

Co-authors: Peter Gibson

2007Timmins NL, Wood LG, Simpson JL, Gibson PG, 'Optimising exhaled breath condensate collection', Respirology (TSANZ Abstracts-Posters), Auckland (2007) [E3]

Co-authors: Lisa Wood, Peter Gibson

2006Mattes J, Simpson JL, Foster PS, Gibson PG, 'Trail is upregulated in the airways of asthmatics', Respirology, Canberra (2006) [E3]
2006Simpson JL, Grissell TV, Douwes J, Scott R, Boyle MJ, Gibson PG, 'Innate immune activation in neutrophilic asthma', The Journal of the Japanese Respiratory Society, Tokyo (2006) [E3]
2006Simpson JL, Scott R, Boyle MJ, Oldham RA, Gibson PG, 'IL-8 levels ininflammatory subtypes of airway disease', Respirology, Canberra (2006) [E3]
2006Simpson JL, Scott R, Boyle MJ, Gibson PG, 'Inflammatory subtypes in asthma with fixed airflow obstruction', Respirology, Canberra (2006) [E3]
2006Baines KJ, Simpson JL, Scott R, Bell NV, Boyle MJ, Gibson PG, 'Enhanced IL-8 release from neutrophils in non-eosinophilic asthma', Respirology, Canberra (2006) [E3]
2006Simpson JL, Scott R, Boyle MJ, Gibson PG, 'Inflammatory subtypes in Asthma with fixed airflow obstruction', American Thoracic Society. Proceedings, San Diego, California (2006) [E3]
2005Wood LG, Garg ML, Blake RJ, Simpson JL, Gibson PG, 'Systemic and airway levels of glutathione and alpha-tocopherol in asthma', Asia Pacific Journal of Clinical Nutrition, Australia (2005) [E3]
Show 78 more
Edit

Grants and Funding

Summary

Number of grants35
Total funding$5,929,290

- Indicates that the researcher may be seeking students for this project.

Click on a grant title below to expand the full details for that specific grant.

2014 (2 grants)

Galectin 3 reduced in non-eosinophilic asthma and associated with impaired macrophage efferocytosis and sputum neutrophil numbers$27,512
Funding Body: John Hunter Hospital Charitable Trust Fund

Project Team
Associate Professor Jodie Simpson, Doctor David Arnold
SchemeRole
Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$27,51220142014
GNo:G1400460

Thoracic Society of Australia and New Zealand Annual Meeting, Adelaide Australia, 4-9 April 2014$2,000
Funding Body: University of Newcastle - Faculty of Health and Medicine

Project Team
Associate Professor Jodie Simpson
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,00020142014
GNo:G1400494

2013 (5 grants)

Inflammometry in Stable COPD; A Randomised Controlled Trial (RCT)$717,071
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor Peter Gibson, Associate Professor Vanessa McDonald, Associate Professor Jodie Simpson, Conjoint Professor Peter Wark
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$717,07120132016
GNo:G1200185

Gene Expression Biomarkers Predict Severe Asthma Inflammatory Phenotype, Activation Mechanisms and Treatment Response$449,307
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Doctor Katie Baines, Conjoint Professor Peter Gibson, Associate Professor Jodie Simpson
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$449,30720132015
GNo:G1200188

BD FACSCanto II Violet Laser (405nm) upgrade including Trigon and 2 photomultiplier tubes (PMTs)$25,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor Peter Wark, Doctor Alan Hsu, Doctor Katie Baines, Associate Professor Jodie Simpson, Conjoint Professor Peter Gibson, Ms Hayley See
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$25,00020132013
GNo:G1201180

DP73 Digital colour and monochrome camera + cellSens software + Xcite120 fluorescence lamp illuminator$20,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Paul Foster, Doctor Alan Hsu, Professor Phil Hansbro, Professor Joerg Mattes, Doctor Katie Baines, Associate Professor Jodie Simpson, Professor Rakesh Kumar, Doctor Nicole Hansbro, Doctor Steven Maltby, Doctor Ming Yang, Doctor Gerard Kaiko, Doctor Jay Horvat, Doctor Simon Keely, Doctor Andrew Jarnicki, Doctor Michael Fricker
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$20,00020132013
GNo:G1201186

ASI 2013, Wellington Australia, 2 - 5 December 2013$1,700
Funding Body: University of Newcastle - Faculty of Health and Medicine

Project Team
Associate Professor Jodie Simpson
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$1,70020132013
GNo:G1301220

2012 (2 grants)

Body plethysmograph respiratory function system$33,076
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor Peter Gibson, Conjoint Professor Peter Wark, Associate Professor Lisa Wood, Associate Professor Jodie Simpson, Doctor Katie Baines, Doctor Vanessa Murphy, Doctor Jeffrey Pretto, Emeritus Professor Michael Hensley, Ms Jenny Mackney
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$33,07620122012
GNo:G1100973

Asian Pacific Society of Respirology, Hong Kong, 14- 16 December 2012$2,000
Funding Body: University of Newcastle - Faculty of Health and Medicine

Project Team
Associate Professor Jodie Simpson
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,00020122012
GNo:G1200874

2011 (3 grants)

Transcriptional Phenotyping of COPD and the relationship between neutrophilic airway inflammation, airway infection and activation of proinflammatory pathways$24,000
Funding Body: John Hunter Hospital Charitable Trust Fund

Project Team
Doctor Katie Baines, Conjoint Professor Peter Gibson, Associate Professor Jodie Simpson
SchemeRole
Research GrantInvestigator
Total AmountFunding StartFunding Finish
$24,00020112011
GNo:G1100635

Identification of a specific biomarker signature that identifies asthma phenotype $23,700
Funding Body: Hunter Medical Research Institute

Project Team
Doctor Katie Baines, Associate Professor Jodie Simpson, Conjoint Professor Peter Gibson
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$23,70020112011
GNo:G1001054

Lung Function (Spirometry) testing and sputum induction equipment - establishing 3 new clinical workstations. Medgraphics CPFS/d USB spirometer with breezesuite software (x3). Laptop computer (x3). Ul$10,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor Peter Gibson, Associate Professor Jodie Simpson, Associate Professor Lisa Wood, Doctor Katie Baines, Conjoint Professor Peter Wark, Doctor Vanessa Murphy
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$10,00020112011
GNo:G1100038

2010 (2 grants)

The pathogenesis of distinct endophenotypes of asthma is underpinned by the collaborative activation of specific PRRs$240,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Associate Professor Jodie Simpson, Dr Simon Phipps
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$240,00020102012
GNo:G0190179

Real time PCR machine (Mastercycler ep realplex2 from Epprndorf) $34,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Associate Professor Jodie Simpson, Conjoint Professor Peter Gibson, Conjoint Professor Peter Wark, Associate Professor Lisa Wood, Doctor Vanessa Murphy, Doctor Robert Scott, Doctor Katie Baines
SchemeRole
Equipment GrantChief Investigator
Total AmountFunding StartFunding Finish
$34,00020102010
GNo:G1000056

2009 (4 grants)

The AMAZES study: asthma and macrolides: the AZithromycin efficacy and safety study$2,991,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor Peter Gibson, Associate Professor Jodie Simpson, Professor John Upham, Associate Professor Paul Reynolds, Dr Ian Yang, Dr Sandra Hodge
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$2,991,00020092013
GNo:G0188843

Epigenetic regulation of airways inflammation in non-eosinophilic asthma$63,354
Funding Body: Asthma Foundation of New South Wales

Project Team
Conjoint Professor Peter Gibson, Doctor Katie Baines, Associate Professor Jodie Simpson
SchemeRole
PhD ScholarshipsInvestigator
Total AmountFunding StartFunding Finish
$63,35420092011
GNo:G0189748

394591 ELx405UV select plate washer and workstation integration kit$27,500
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor Peter Gibson, Doctor Xiao Yan He, Associate Professor Jodie Simpson, Associate Professor Lisa Wood, Conjoint Professor Peter Wark
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$27,50020092009
GNo:G0189853

PULSE Early Career Researcher of the year$10,000
Funding Body: Hunter Medical Research Institute

Project Team
Associate Professor Jodie Simpson
SchemeRole
PULSE Early Career Researcher of the Year AwardChief Investigator
Total AmountFunding StartFunding Finish
$10,00020092009
GNo:G0189893

2008 (5 grants)

Molecular mechanisms and treatment of non-eosinophilic asthma$300,000
Funding Body: Hunter Medical Research Institute

Project Team
Associate Professor Jodie Simpson, Doctor Katie Baines
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$300,00020082010
GNo:G0188825

Characterisation and treatment of innate immune dysfunction in older people with obstructive airway disease$254,000
Funding Body: Australian Respiratory Council

Project Team
Associate Professor Jodie Simpson
SchemeRole
Ann Woolcock FellowshipChief Investigator
Total AmountFunding StartFunding Finish
$254,00020082011
GNo:G0188282

Becton Dickinson high throughout sampler for the FACSCanto II cytometry system$35,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor Peter Wark, Conjoint Professor Peter Gibson, Associate Professor Jodie Simpson, Associate Professor Lisa Wood, Doctor Vanessa Murphy, Professor Phil Hansbro
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$35,00020082008
GNo:G0188547

Understanding non-eosinophilic asthma: triggers and treatment$10,000
Funding Body: Hunter Medical Research Institute

Project Team
Associate Professor Jodie Simpson, Conjoint Professor Peter Gibson
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$10,00020082008
GNo:G0188559

American Thoracic Society Annual Meeting, Toronto, Canada, 16/5/2008 - 21/5/2008$2,500
Funding Body: University of Newcastle

Project Team
Associate Professor Jodie Simpson
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,50020082008
GNo:G0188580

2007 (8 grants)

Characterisation and Treatment of Innate Immune Dysfunction in Older People with Obstructive Airway Disease$416,875
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Associate Professor Jodie Simpson, Conjoint Professor Peter Gibson, Professor Phil Hansbro
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$416,87520072009
GNo:G0186426

In vitro response of bronchial epithelial cells and activation of lymphocytes to infection with rhinovirus$58,848
Funding Body: John Hunter Hospital Charitable Trust Fund

Project Team
Conjoint Professor Peter Wark, Professor Phil Hansbro, Associate Professor Jodie Simpson
SchemeRole
Research GrantInvestigator
Total AmountFunding StartFunding Finish
$58,84820072009
GNo:G0188095

Nitric Oxide Monitoring System (NIOX)$45,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor Peter Gibson, Conjoint Associate Professor Vicki Clifton, Conjoint Professor Warwick Giles, Emeritus Professor Michael Hensley, Doctor Vanessa Murphy, Conjoint Professor Peter Wark, Associate Professor Vanessa McDonald, Associate Professor Jodie Simpson, Conjoint Associate Professor Bruce Whitehead, Professor Paul Foster, Professor Phil Hansbro, Associate Professor Lisa Wood
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$45,00020072007
GNo:G0188193

In vitro response of bronchial epithelial cells and activation of lymphocytes from COPD patients by infection with rhinovirus, respiratory syncytial virus and haemophilus influenza$25,000
Funding Body: GlaxoSmithKline Australia

Project Team
Conjoint Professor Peter Wark, Professor Phil Hansbro, Associate Professor Jodie Simpson
SchemeRole
Support GrantInvestigator
Total AmountFunding StartFunding Finish
$25,00020072008
GNo:G0188309

Class II biohazard containment hood and carbon dioxide cell culture incubator$20,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor Peter Wark, Conjoint Professor Peter Gibson, Associate Professor Jodie Simpson, Doctor Vanessa Murphy, Associate Professor Lisa Wood, Professor Paul Foster, Professor Phil Hansbro
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$20,00020072007
GNo:G0188192

Elucidation of the association between Haemophilus influenzae infection and neutrophilic asthma.$20,000
Funding Body: Hunter Medical Research Institute

Project Team
Professor Phil Hansbro, Associate Professor Jodie Simpson, Professor Paul Foster, Conjoint Professor Margaret Dunkley
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$20,00020072007
GNo:G0187206

Hewlett Packard 7890 series gas chromatograph with accessories$20,000
Funding Body: NHMRC (National Health & Medical Research Council)

Thoracic Society of Australia and New Zealand, 23-28/3/07$1,765
Funding Body: University of Newcastle

Project Team
Associate Professor Jodie Simpson
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$1,76520072007
GNo:G0187371

2006 (4 grants)

Airway inflamation in people over 55$11,682
Funding Body: University of Newcastle

Project Team
Associate Professor Jodie Simpson
SchemeRole
Early Career Researcher GrantChief Investigator
Total AmountFunding StartFunding Finish
$11,68220062006
GNo:G0186232

American Thoracic Society International Scientific meeting$3,000
Funding Body: Hunter Medical Research Institute

Project Team
Associate Professor Jodie Simpson
SchemeRole
PULSE Education PrizeChief Investigator
Total AmountFunding StartFunding Finish
$3,00020062006
GNo:G0186155

American Thoracic society Annual Meeting 19-24 MAY 2006$2,400
Funding Body: University of Newcastle

Project Team
Associate Professor Jodie Simpson
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,40020062006
GNo:G0186471

American Thoracic Society conference$2,000
Funding Body: Ian Potter Foundation

Project Team
Associate Professor Jodie Simpson
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,00020062006
GNo:G0186176
Edit

Research Supervision

Number of current supervisions3
Total current UoN Masters EFTSL0.5
Total current UoN PhD EFTSL0.4

For supervisions undertaken at an institution other that the University of Newcastle, the institution name is listed below the program name.

Current Supervision

CommencedProposed
Completion
ProgramSupervisor TypeResearch Title
20142016M Philosophy (Medicine)Principal SupervisorThe Effects of Galectin-3 on Alveolar Macrophage Function in Asthma
20092013PhD (Medicine)Co-SupervisorEpigenetic Regulation of Airway Inflammation in Asthma
20072012PhD (Medicine)Co-SupervisorCharacterising Innate Immune Responses and the Role of PD-1 in Patients with COPD

Past Supervision

YearProgramSupervisor TypeResearch Title
2012PhD (Immunology & Microbiol)Co-SupervisorModulation of Responses in Allergic Airways Disease by Haemophilus Influenzae Infection
Edit

Associate Professor Jodie Simpson

Work Phone(02) 40420148
Fax(02) 4985 5850
Email
PositionSenior Research Fellow
School of Medicine and Public Health
Faculty of Health and Medicine
The University of Newcastle, Australia
Office
HMRI Level 2 Room 2101,
HMRI,
John Hunter Hospital
URL:www.newcastle.edu.au/profile/jodie-simpson