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Career Summary

Biography

Associate Professor  Maguire is an Early Career Researcher and Senior Academic in the School of Nursing and Midwifery. Her key research interests are in stroke epidemiology, stroke outcome and the genetics of stroke. She has 13 years experience as a clinical researcher working in medical and nursing observational and genetic epidemiology research and has experience in the design, conduct and management of large scale international clinical research, in particular case-control association studies. She also has experience in survey design and development, and interview and focus group methodologies. She is the current Chair of the International Stroke Genetics Consortia, national manager of a current NHMRC project grant conducting the first Australian Genome Wide Association study in Ischaemic stroke and sits on the management and steering committees for this national and international multi-centre collaboration. Associate Professor Maguire was recently awarded a prestigious HMRI Pulse Education Prize, and is currently launching a program of stroke research within the School of Nursing and Midwifery.

Qualifications

  • Doctor of Philosophy, University of Newcastle, 13/12/2010
  • Graduate Certificate in Child & Adolescent Health, NSW College of Nursing, 26/02/1996
  • Bachelor of Nursing (Honours), University of Newcastle, 14/08/2000
  • Bachelor of Arts, University of New England, 08/04/1995

Research

Research keywords

  • Biostatistics-genetic association studies
  • Case control studies
  • Gene-environment interaction analysis
  • Genetic Epidemiology
  • Qualitative methods- phenomenology, thematic analysis
  • Research Program Leader
  • Stroke Epidemiology and Research
  • Stroke Genetic Research

Research expertise

Associate Professor Maguire has over 25 years of clinical experience as a registered nurse with both paediatric and adult patients in acute care and community based health facilities. She is an Early Career Researcher and Honours Program Convenor in the School of Nursing and Midwifery, University of Newcastle. Jane has over 15 year’s research experience in both quantitative and qualitative methodologies. Her doctoral studies focussed on candidate genes in stroke risk and led to her substantial international profile and current elected Chair of the International Stroke Genetics Consortia http://www.strokegenetics.com/news/steering-committee-changes. Jane’s role on this committee is as a result of her endeavours during her doctoral studies, a population based genetic association study investigating the genetic epidemiology of stroke and her stroke team’s research program within the UoN PRC Translational Neuroscience and Mental Health and the Australian Stroke Genetics Collaboration. Dr Maguire is particularly interested in the genetics of early and later outcomes for patients following ischaemic stroke (Maguire et al 2009). She is currently collaborating with colleagues across the UK and USA to further investigate the genetic basis of stroke outcome. This involves using a genome wide association design and pooling the largest global collection of data for this phenotype consisting of fourteen cohorts of acute stroke patients. Over the last 5 years Jane has presented the progress of this research at the European Stroke Conference, The World Cardiology Conference, numerous International Stroke Genetics Consortium workshops, Malaysian Joint Medical Conference and the Stroke Society of Australasia's Annual Scientific Meetings. Jane is a reviewer for the Journal of Clinical Neurosciences, Journal of Stroke and Cerebrovascular Disease and American Heart Foundation's Stroke and has over 20 peer reviewed publications.Key research interests are in stroke genetics, stroke epidemiology and outcome.

Languages

  • English

Fields of Research

CodeDescriptionPercentage
110999Neurosciences Not Elsewhere Classified40
110299Cardiovascular Medicine And Haematology Not Elsewhere Classified30
111706Epidemiology30

Memberships

Body relevant to professional practice.

  • Member - National Stroke Foundation

Committee/Associations (relevant to research).

  • Member - School of Nursing and Midwifery Research Committee
  • Fellow - Priority Research Centre Brain and Mental Health
  • Member - Stroke Society of Australasia
  • Member - National Brain Foundation
  • Member - Florey Institute of Neuroscience and Mental Health

Collaboration

Dr Maguire is currently collaborating with the International Stroke Genetics Consortium (ISGC) as a member of and the National manager for , the Australian Stroke Genetics Collaboration (ASGC). These collaborations include the ISGC Belgium group, led by Prof Vincent Thijs; ISGC Edinburgh group, led by Prof Cathy Sudlow; ISGC Boston group, led by Dr Natalia Rost; ISGC London based Metastroke group, led by Prof Hugh Markus; ISGC USA group, led by Prof Bard Worrell; ISGC Maryland USA group, led by Prof Braxton Mitchell.

Nationally, Dr Maguire is collaborating with an ASGC member based in Townsville as an associate investigator on 2011 funded NHMRC grant ID 1011649 for a study titled 'Role of Tenascin-C and TLR-4 in carotid atherosclerosis related stroke'.

Administrative

Administrative expertise

Since my appointment in 2011 as senior lecturer in the School of Nursing and Midwifery, I have accepted the responsibility of the Program Convenor for Honours students and Course Coordinator for a large undergraduate first year course. I have also accepted the responsibility and made substantive and sustained contributions to scholarship committees convened to select appropriate recipients for the Hunter New England Honours Scholarship, the Aston Scholarship and the ADSSI Honours Scholarship. I have been involved in convening and co-coordinating as Program Convenor and Course Coordinator for 6 undergraduate courses in the Bachelor of Nursing Undergraduate Program and the Honours Program. This includes teaching through a variety of mediums, includes face-to-face and online tutorials. These roles also include peer reviewed quality assurance processes and frequent curriculum review. I have actively promoted the Honours Program to potential undergraduate students during lectures and tutorials and I have met and discussed options and given advice regarding the program structure and scholarship opportunities with interested students from all years of the undergraduate degree.

Teaching

Teaching keywords

  • Clinical supervision
  • Online Course Development
  • Program Convenor
  • Undergraduate Course Development
  • Undergraduate Teaching

Teaching expertise

Outstanding contribution to teaching 2011-2012 At the commencement of my academic teaching position with the School of Nursing and Midwifery, I engaged my intellectual capacity, motivation, high level organisational skills, collaborative capacity, drive and determination to develop the new curriculum for NURS1201 Foundations in Professional Practice 1B delivered for the first time in S2 2012. This is a 20 unit course and is delivered to over 500 first year students in semester 2.In addition to my input into designing all tutorials, lectures and online resources, I have added a unique element in the form of clinical scenarios that are based on real life stimulus material. I had the privilege of being offered the use of personal diaries donated for educational purposes which I used to develop a series of clinical scenarios. These scenarios not only gave the students a unique insight into the experiences of a person with a complex disease (multiple sclerosis), but also created an opportunity for the students to seek and create a community connection with Lyn in the real world. This has been mutually beneficial. Students have also reported how invaluable this has been to them as a direct application of person centred care and as a student resource. I have been the Course Coordinator for this course since its inception in S2 2011. This large 1st year course commenced with 536 students. My commitment to teaching excellence, and strong interpersonal and organisational skills combined with a team of dedicated tutors resulted in 74.2% of the students successfully completing this Foundations course. At the time of grade reporting there were 458, 489 students enrolled in the course for 2011 and 2012 respectively. This represents a loss of approximately 78 students (14.5%) and 74 (13%) respectively.

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Highlighted Publications

For publications that are currently unpublished or in-press, details are shown in italics.

YearCitationAltmetricsLink
2012Holliday EG, Maguire JM, Evans T-J, Koblar SA, Jannes J, Sturm J, et al., 'Common variants at 6p21.1 are associated with large artery atherosclerotic stroke', Nature Genetics, 44 1147-1153 (2012) [C1]
2012Cheng YC, Anderson CD, Bione S, Keene K, Maguire JM, Nalls M, et al., 'Are myocardial infarction-associated single-nucleotide polymorphisms associated with ischemic stroke?', Stroke, 43 980-U143 (2012) [C1]
2014Traylor M, Mäkelä KM, Kilarski LL, Holliday EG, Devan WJ, Nalls MA, et al., 'A novel MMP12 locus is associated with large artery atherosclerotic stroke using a genome-wide age-at-onset informed approach.', PLoS Genet, 10 e1004469 (2014) [C1]

Publications

For publications that are currently unpublished or in-press, details are shown in italics.

Click on a category title below to expand the list of citations for that specific category.

Chapter (1 outputs)

YearCitationAltmetricsLink
2013Holliday EG, Oldmeadow CJ, Maguire JM, Attia JR, 'Candidate gene association studies in stroke', Stroke Genetics, Springer Verlag, London 9-23 (2013) [B1]

Journal article (21 outputs)

YearCitationAltmetricsLink
2014Traylor M, Mäkelä KM, Kilarski LL, Holliday EG, Devan WJ, Nalls MA, et al., 'A novel MMP12 locus is associated with large artery atherosclerotic stroke using a genome-wide age-at-onset informed approach.', PLoS Genet, 10 e1004469 (2014) [C1]
2014Golledge J, Clancy P, Maguire J, Levi C, Sturm J, Lincz L, et al., 'Plasma angiopoietin-1 is lower after ischemic stroke and associated with major disability but not stroke incidence', Stroke, 45 1064-1068 (2014)
2014van der Riet P, Maguire J, Dedkhard S, Sibbritt D, 'Are traditional Thai therapies better than conventional treatment for stroke rehabilitation? A quasi-experimental study', European Journal of Integrative Medicine, (2014)
2014Golledge J, Clancy P, Maguire J, Lincz L, Koblar S, McEvoy M, et al., 'Plasma angiopoietin-1 is lower after ischemic stroke and associated with major disability but not stroke incidence', Stroke, (2014)
2014Maguire JM, Clancy P, LINCZ L, Golledge J, Koblar S, MCEVOY M, 'TENASCIN C is increased in atherothrombotic stroke patients and has an anti-inflammatory effect in the human carotid artery', BioFactors, 00 (2014)
2014Clancy P, Lincz LF, Maguire J, McEvoy M, Koblar SA, Golledge J, 'Tenascin-C is increased in atherothrombotic stroke patients and has an anti-inflammatory effect in the human carotid artery.', Biofactors, 40 448-457 (2014)
2013Adib-Samii P, Rost N, Traylor M, Devan W, Biffi A, Lanfranconi S, et al., '17q25 Locus is associated with white matter hyperintensity volume in ischemic stroke, but not with lacunar stroke status', Stroke, 44 1609-1615 (2013) [C1]
2013Yadav S, Cotlarciuc I, Munroe PB, Khan MS, Nalls MA, Bevan S, et al., 'Genome-Wide Analysis of Blood Pressure Variability and Ischemic Stroke', Stroke, 44 2703-2709 (2013) [C1]
2012Cheng YC, Anderson CD, Bione S, Keene K, Maguire JM, Nalls M, et al., 'Are myocardial infarction-associated single-nucleotide polymorphisms associated with ischemic stroke?', Stroke, 43 980-U143 (2012) [C1]
2012Traylor M, Farrall M, Holliday EG, Sudlow C, Hopewell JC, Cheng Y-C, et al., 'Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE Collaboration): A meta-analysis of genome-wide association studies', The Lancet Neurology, 11 951-962 (2012) [C1]
2012Holliday EG, Maguire JM, Evans T-J, Koblar SA, Jannes J, Sturm J, et al., 'Common variants at 6p21.1 are associated with large artery atherosclerotic stroke', Nature Genetics, 44 1147-1153 (2012) [C1]
2012O'Brien AP, McDonald VM, Maguire JM, 'Editorial: Nursing and midwifery research and scholarship in the Hunter New England Local Health District', HNE Handover, 5 2 (2012) [C3]
2011Golledge J, Clancy P, Maguire JM, Lincz L, Koblar S, 'The role of tenascin C in cardiovascular disease', Cardiovascular Research, 92 19-28 (2011) [C1]
2011Maguire JM, Thakkinstian A, Levi CR, Lincz L, Bisset L, Sturm J, et al., 'Impact of COX-2 rs5275 and rs20417 and GPIIIa rs5918 polymorphisms on 90-day ischemic stroke functional outcome: A novel finding', Journal of Stroke and Cerebrovascular Diseases, 20 134-144 (2011) [C1]
2010Lemmens R, Buysschaert I, Geelen V, Fernandez-Cadenas I, Montaner J, Schmidt H, et al., 'The Association of the 4q25 susceptibility variant for atrial fibrillation with stroke is limited to stroke of cardioembolic etiology', Stroke, 41 1850-1857 (2010) [C1]
2008Maguire JM, Thakkinstian A, Sturm J, Levi CR, Lincz L, Parsons MW, et al., 'Polymorphisms in platelet glycoprotein 1b [alpha] and factor VII and risk of ischemic stroke', Stroke, 39 1710-1716 (2008) [C1]
2007Levett-Jones TL, Lathlean J, Maquire J, McMillan MA, 'Belongingness: A critique of the concept and implications for nursing education', Nurse Education Today, 27 210-218 (2007) [C1]
2007FitzGerald M, McMillan M, Maguire JM, 'Nursing from the casual pool: Focus group study to explore the experiences of casual nurses', International Journal of Nursing Practice, 13 229-236 (2007)
2006McNeill PM, Kerridge IH, Henry DA, Stokes BJ, Hill SR, Newby DA, et al., 'Giving and receiving of gifts between pharmaceutical companies and medical specialists in Australia', Internal Medicine Journal, 36 571-578 (2006) [C1]
2005Kerridge I, Maguire JM, Newby DA, McNeill PM, Henry DA, Hill SR, et al., 'Cooperative partnerships or conflict-of-interest? A national survey of interaction between the pharmaceutical industry and medical organizations', Internal Medicine Journal, 35 206-210 (2005) [C1]
2005Henry DA, Kerridge IH, Hill SR, McNeill PM, Doran E, Newby DA, et al., 'Medical specialists and pharmaceutical industry-sponsored research: a survey of the Australian experience', Medical Journal of Australia, 182 557-560 (2005) [C1]
Show 18 more

Conference (6 outputs)

YearCitationAltmetricsLink
2014Maguire JM, Lindgren A, Bevan S, Jern C, Jimenez-Condez J, Lee JM, et al., 'GISCOME Genetics of Ischaemic stroke Outcome study', Cerebrovascular Diseases, Nice France (2014)
2014Maguire JM, Lindgren A, Bevan S, Jern C, Fernandez-Cadenas I, Lemmens R, et al., 'GISCOME ¿ Genetic influences on Ischaemic Stroke functional Outcome: a genome wide association study', Stroke Society of Australasia, Hamilton Island, Queensland (2014)
2013Crowfoot GM, Van Der Riet P, Maguire J, 'From symptom onset to doorway: Capturing the stories of patients with Transient Ischaemic Attack', International Journal of Stroke, Queensland (2013) [E3]

Co-authors: Pamela Vanderriet

2012Maguire JM, holliday E, 'Abstract 13: A Locus on Chromosome 6p21 is Associated with Large Artery Atherosclerotic Ischemic Stroke', International Stroke Conference Oral Abstracts Session Title: Community/Risk Factors Oral Abstracts, New Orleans, La. (2012)
2011Maguire JM, Holliday EG, Sturm J, Golledge J, Lewis M, Koblar S, et al., 'Australian stroke genetics collaborative: Genetic associations with ischaemic stroke functional outcome', International Journal of Stroke, Adelaide, SA (2011) [E3]
2010Maguire JM, Thakkinstian A, Levi CR, Lincz L, Bissett KE, Sturm J, et al., 'Genetic influences on ischemic stroke 90-day functional outcome: A novel association', Circulation, Beijing (2010) [E3]
Show 3 more
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Grants and Funding

Summary

Number of grants8
Total funding$59,000

- Indicates that the researcher may be seeking students for this project.

Click on a grant title below to expand the full details for that specific grant.

2014 (2 grants)

Biological characterisation of genetic associations for large artery atherosclerotic stroke$25,000
Funding Body: Hunter Medical Research Institute

Project Team
Doctor Liz Holliday, Professor Rodney Scott, Conjoint Professor Chris Levi, Professor John Attia, Associate Professor Jane Maguire
SchemeRole
Stroke Research Project GrantInvestigator
Total AmountFunding StartFunding Finish
$25,00020142014
GNo:G1301340

International Stroke genetics Consortia 16th Workshop, Paris France, 5-7 November 2014$2,000
Funding Body: University of Newcastle - Faculty of Health and Medicine

Project Team
Associate Professor Jane Maguire
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,00020142014
GNo:G1400426

2013 (3 grants)

The genetic determinants of brain haemorrhage associated with stroke thrombolysis$10,000
Funding Body: Hunter Medical Research Institute

Project Team
Conjoint Professor Chris Levi, Professor John Attia, Doctor Liz Holliday, Dr Simon Koblar, Professor Rodney Scott, Conjoint Associate Professor Jonathan Sturm, Associate Professor Jonathan Rosand, Doctor Lisa Lincz, Associate Professor Jane Maguire
SchemeRole
Near MissInvestigator
Total AmountFunding StartFunding Finish
$10,00020132013
GNo:G1300704

The genetic determinants of brain haemorrhage associated with stroke thrombolysis$10,000
Funding Body: University of Newcastle

Project Team
Conjoint Professor Chris Levi, Professor John Attia, Doctor Liz Holliday, Dr Simon Koblar, Professor Rodney Scott, Conjoint Associate Professor Jonathan Sturm, Associate Professor Jonathan Rosand, Doctor Lisa Lincz, Associate Professor Jane Maguire
SchemeRole
Near Miss GrantInvestigator
Total AmountFunding StartFunding Finish
$10,00020132013
GNo:G1300475

International Stroke genetics consortia 14th Workshop, Lund Sweden, 13-16 November 2013$1,500
Funding Body: University of Newcastle - Faculty of Health and Medicine

Project Team
Associate Professor Jane Maguire
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$1,50020132013
GNo:G1301043

2012 (1 grants)

Stroke Research Program$5,000
Funding Body: University of Newcastle

Project Team
Associate Professor Jane Maguire
SchemeRole
New Staff GrantChief Investigator
Total AmountFunding StartFunding Finish
$5,00020122012
GNo:G1200456

2011 (2 grants)

PULSE Education Prize$4,000
Funding Body: Hunter Medical Research Institute

Project Team
Associate Professor Jane Maguire
SchemeRole
PULSE Education PrizeChief Investigator
Total AmountFunding StartFunding Finish
$4,00020112011
GNo:G1001055

International Stroke Genetics Consortium, Levven, Belgium, 16 - 17 June 2011$1,500
Funding Body: University of Newcastle - Faculty of Health and Medicine

Project Team
Associate Professor Jane Maguire
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$1,50020112011
GNo:G1100581
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Research Supervision

Number of current supervisions3
Total current UoN PhD EFTSL1.15

For supervisions undertaken at an institution other that the University of Newcastle, the institution name is listed below the program name.

Current Supervision

CommencedProposed
Completion
ProgramSupervisor TypeResearch Title
20142022PhD (Nursing)Co-SupervisorWhat is the Survivors' Experience of a Cardio Pulmonary Resuscitation?
20132017PhD (Nursing)Co-SupervisorThe Influence of Healthcare Pathways upon the Outcomes and Experiences of People with TIA or Minor Stroke: A Mulitmethod Approach
20132017PhD (Nursing)Co-SupervisorAn Ethnographic Study of the Subculture of Chaay Rak Chaay (Gay Men) in Thailand from a Nursing Perspective
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Associate Professor Jane Maguire

Work Phone49216230
Cell / Mobile Phone0414420062
Fax49 216301
Email
PositionAssociate Professor
School of Nursing and Midwifery and PRC Brain and Mental Health Research Group, HMRI
School of Nursing and Midwifery
Faculty of Health and Medicine
The University of Newcastle, Australia
Focus AreaNursing
Office
RW-2-39,
Richardson Wing,
School of Nursing and Midwifery Richardson Wing
URL:www.newcastle.edu.au/profile/jane-maguire