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Career Summary

Biography

I undertook a PhD at the University of Bristol on the effects of cryopreservation on human gametes and embryos under the supervision of Dr Chris Ford. On completion of my PhD I moved to the Department of Biochemistry on a Wellcome Trust postdoctoral fellowship to work in the lab of Prof Len Hall where I identified genes involved in male fertility and characterised their role in fertilization.

In 2000 I took up a position in the Pest Animal Control CRC in CSIRO Sustainable Ecosystems in Canberra where I worked on the development of virally vectored immunocontraception for rabbit control. In 2002 I was recruited to the University of Newcastle where I established my research group. Work in my lab focuses on the RNA binding proteins and their roles in spermatogenesis and folliculogenesis and proteins involved in meiosis. In addition we study cytokines that control the activation of primordial follicles in the mammalian ovary and ovotoxic xenobiotics which cause oocyte loss and early menopause.

I have published in Cell Stem Cell, PNAS, Developmental Biology and Toxicological Sciences . We use a number of mouse models and a wide range of cell and molecular biology techniques to monitor cell signalling dynamics in primary culture, identify novel target proteins, functionally characterise translational repressors and activators and use structural modelling to design inhibitors of these interactions. We collaborate extensively through the ARC Centre of Excellence in Biotechnology and Development as well as with individual groups in the USA and Australia.

Qualifications

  • PhD, University of Bristol
  • Bachelor of Science (Honours), University of Glasgow - Scotland

Research

Research keywords

  • Ovarian Biology
  • Reproductive Sciences
  • Spermatogonial Stem Cells

Research expertise

My research in the field of testicular biology has focused on spermatogonial development with particular emphasis on the identification and characterization of key regulators of spermatogonial stem cell replication (HOW), microRNA in germ cells, stem cell maintenance (Musashi), and male germ cell differentiation (c-Kit) and sperm function (Fertilin) (see McIver et al 2012 Human Reproduction Update, Monk et al 2010 Cell Stem Cell, Monk et al PLoS One 2012, Siddall et al 2006 PNAS, Prahbu et al 2006 Reproduction, McLaughlin et al 2001 Molecular Human Reproduction).

In addition we study cytokines that control the activation of primordial follicles in the mammalian ovary and ovotoxic xenobiotics which cause oocyte loss and early menopause ( see Sutherland et al 2012 J Cellular Physiology, Sobinoff et al 2012, 2011, 2010 Toxicological Sciences, Blackmore et al 2004 Biology of Reproduction, Holt et al 2006 Developmental Biology, Hutt et al 2006 Biology of Reproduction, McLaughlin & McIver Reproduction 2009).

In addition my lab has contributed to cell and molecular research in human and animal assisted reproduction with an emphasis on the characterization of gene and protein expression and function in male and female gametogenesis, reproductive tracts, roles in fertilization and as contraceptive targets (McLaughlin et al 2001, Asquith et al 2004, 2005, Nixon et al 2007, 2009, McLaughlin et al 2010, Redgrove et al 2011, Walker et al 2011).

Fields of Research

CodeDescriptionPercentage
060199Biochemistry And Cell Biology Not Elsewhere Classified55
060699Physiology Not Elsewhere Classified30
111499Paediatrics And Reproductive Medicine Not Elsewhere Classified15

Memberships

Committee/Associations (relevant to research).

  • Programme Committee - Society of Reproductive Biology

Invitations

Primordial follicle activation and development
University of Adelaide, Australia (Invited seminar speaker)
2005

Collaboration

Collaborators include:

Dr Shaun Roman, Dr Brett Nixon, Prof John Aitken, Prof Adam McCluskey (University of Newcastle)

Prof Keith Jones, Dr Janet Holt and Dr Julie Merriman Jones (University of Newcastle)

Dr Gary Hime (University of Melbourne) and Prof Minx Fuller (Standford University)

Prof Kate Loveland & Prof Moira O'Bryan (Monash University)

Dr Darryl Russell and Dr Rebecca Robker (University of Adelaide)

Prof Peter Koopman and Dr Jo Bowles (University of Queensland)

Prof Ken Beagley (QUT) & Dr C Wira (Dartmouth University)

Administrative

Administrative expertise

University Expertise

Animal Ethics Committee Member

Deputy Head of School of Environmental & Life Sciences

Institutional Biosafety Committee Member

ERA Cluster 8 committee member

Animal Ethics Review Committee Member

Faculty of Science Research and Research Training Committee Member

Manager and Instructor-in-charge of Imaging Suite, Life Sciences Building (2001 - present)

Chair of School Committee Review of Induction Materials for Honours students (2002 - 3)

School Representative for Faculty of Science & IT International Committee (2004 - 2005)

Biological Sciences Representative for School Research Higher Degree Progress Committee (2003 - present)

Coordinator Level 1000 Biology - 500 students and 50 staff and Level 2000 Biology - 100 students and 10 staff

Professional Activities

Reviewer Grant Giving Bodies: NHMRC GRP member, Medical Research Council UK, the Biotechnology & Biological Sciences Research Council UK, and the Wellcome Trust. I also review for a number of specialist Reproduction journals.

Positions in Learned Societies: President elect of Society for Reproductive Biology, Chairman of the British Andrology Society (1997-2000) and a Director of the Journal of Reproduction & Fertility (Ltd.).

Committee member: British Fertility Society Association of Clinical Embryologists, Society for Reproductive Biology and the Society for Low Temperature Biology.

Editor: multiple peer reviewed clinical guidelines and am an adviser to the United States of America Congress, Office of Technology Assessment and the UK Government Department of Health and the Human Fertilization and Embryology Authority.

Teaching

Teaching keywords

  • Biochemistry
  • Biology
  • Biotechnology
  • Immunobiology

Teaching expertise

Senior Lecturer, Tutor & Demonstrator in Cell and Molecular Biology, Biochemistry, Immunobiology and Biotechnology

(1000,2000 and 3000level)

Implementation first ever Web-based delivery of all Level 1000 courses via Blackboard.

Overseeing implementation of on-line assessments, and simulated laboratory computer experiments.

Implementation Turnitin anti-plagiarism and collusion educational software for BIOL1000 cohort (2004).

Awarded Graduate Certificate in Tertiary Teaching

University of Newcastle 2006

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Publications

No publications.

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Grants and Funding

Summary

Number of grants69
Total funding$28,293,907

For project grants received where the lead institution is other than the University of Newcastle, details are shown in italics.

- Indicates that the researcher may be seeking students for this project.

Click on a grant title below to expand the full details for that specific grant.

2013 (4 grants)

Novel function of heat shock protein 2A in the regulation of human sperm-egg interactions$292,182
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Associate Professor Brett Nixon, Laureate Professor John Aitken, Professor Eileen McLaughlin
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$292,18220132015
GNo:G1200193

Leica TP 1020 Automatic Tissue Processor for histology applications$35,000
Funding Body: NHMRC (National Health & Medical Research Council)

Dynamin - role in sperm oocyte interaction$10,000
Funding Body: Hunter Medical Research Institute

Project Team
Professor Eileen McLaughlin, Associate Professor Brett Nixon, Professor Adam McCluskey
SchemeRole
Near MissChief Investigator
Total AmountFunding StartFunding Finish
$10,00020132013
GNo:G1300700

Dynamin - role in sperm oocyte interaction$10,000
Funding Body: University of Newcastle

Project Team
Professor Eileen McLaughlin, Associate Professor Brett Nixon, Professor Adam McCluskey
SchemeRole
Near Miss GrantChief Investigator
Total AmountFunding StartFunding Finish
$10,00020132013
GNo:G1300483

2012 (4 grants)

Role of Musashi in the regulation of cell cycle proteins$280,000
Funding Body: ARC (Australian Research Council)

Project Team
Professor Eileen McLaughlin, Dr Gary Hime, Professor Margaret Fuller
SchemeRole
Discovery ProjectsChief Investigator
Total AmountFunding StartFunding Finish
$280,00020122014
GNo:G1100068

Hedgehog Signalling in Spermatogenesis$150,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Dr Kate Loveland, Professor Eileen McLaughlin
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$150,00020122014
GNo:G1101100

BMG SPECTROstar Nano$15,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Laureate Professor John Aitken, Professor Eileen McLaughlin, Ms Belinda Nixon, Doctor Shaun Roman, Doctor Mark Baker, Doctor Geoffry De Iuliis, Doctor Lisa Mitchell, Doctor Matthew Jobling
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$15,00020122012
GNo:G1100971

Ultrasonic Homogenizer System and -80 ÂșC Freezers for chemical and biological sample storage$10,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Adam McCluskey, Professor Eileen McLaughlin, Professor Peter Lewis, Ms Belinda Nixon, Doctor Shaun Roman, Doctor Jennette Sakoff, Doctor Ian Grainge
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$10,00020122012
GNo:G1100986

2011 (7 grants)

Gamete-specific knockout of Fizzy-Related to examine its meiotic role in oocytes and sperm$600,000
Funding Body: ARC (Australian Research Council)

Project Team
Professor Eileen McLaughlin, Conjoint Professor Keith Jones, Professor Sergio Moreno
SchemeRole
Discovery ProjectsChief Investigator
Total AmountFunding StartFunding Finish
$600,00020112014
GNo:G1000020

Establishment of a comprehensive regional biophysical analysis facility $500,000
Funding Body: ARC (Australian Research Council)

Project Team
Professor Peter Lewis, Professor Nicholas Dixon, Professor Eileen McLaughlin, Professor Adam McCluskey, Associate Professor Aaron Oakley, Professor Paul Foster, Laureate Professor John Aitken, Associate Professor Jennifer Beck, Dr Michael Kelso, Professor Graham Nicholson, Associate Professor Elizabeth Harry, Professor Ian Charles, Associate Professor Steven Djordjevic
SchemeRole
Linkage Infrastructure Equipment & Facilities (LIEF)Investigator
Total AmountFunding StartFunding Finish
$500,00020112011
GNo:G1000630

Chemical Biology$444,961
Funding Body: University of Newcastle

Establishment of a comprehensive regional biophysical analysis facility $230,000
Funding Body: ARC (Australian Research Council)

Project Team
Professor Peter Lewis, Professor Nicholas Dixon, Professor Eileen McLaughlin, Professor Adam McCluskey, Associate Professor Aaron Oakley, Professor Paul Foster, Laureate Professor John Aitken, Associate Professor Jennifer Beck, Dr Michael Kelso, Professor Graham Nicholson, Associate Professor Elizabeth Harry, Professor Ian Charles, Associate Professor Steven Djordjevic
SchemeRole
Linkage Infrastructure Equipment & Facilities (LIEF) Partner fundingInvestigator
Total AmountFunding StartFunding Finish
$230,00020112011
GNo:G1100484

Towards a Chlamydia vaccine for males: The key role of mucosal IgA$35,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Kenneth Beagley, Professor Eileen McLaughlin
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$35,00020112011
GNo:G0190618

SLX4 - a key regulator of male germ cell development and DNA repair$25,000
Funding Body: Hunter Medical Research Institute

Project Team
Professor Eileen McLaughlin, Associate Professor Brett Nixon
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$25,00020112011
GNo:G1001000

Eppendorf mastercycler pro with thermomixer comfort and 5430R centrifuge$15,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Eileen McLaughlin, Professor Peter Lewis, Professor Adam McCluskey, Conjoint Professor Keith Jones, Associate Professor Brett Nixon, Doctor Shaun Roman, Doctor Jennette Sakoff, Doctor Ian Grainge, Doctor Janet Holt, Doctor Xiao Yang
SchemeRole
Equipment GrantChief Investigator
Total AmountFunding StartFunding Finish
$15,00020112011
GNo:G1100028

2010 (9 grants)

Development of a humane non-surgical sterilization method for domestic animals$1,006,825
Funding Body: Found Animals Foundation Inc

Project Team
Laureate Professor John Aitken, Professor Eileen McLaughlin, Professor Adam McCluskey
SchemeRole
Michelson Grants in Reproductive BiologyInvestigator
Total AmountFunding StartFunding Finish
$1,006,82520102012
GNo:G0900113

Sex Ratio and Sterility for Commercial animal production - round 5 Cluster$700,000
Funding Body: CSIRO - Commonwealth Scientific and Industrial Research Organisation

Project Team
Laureate Professor John Aitken, Professor Eileen McLaughlin, Doctor Shaun Roman
SchemeRole
National Research Flagship ClusterInvestigator
Total AmountFunding StartFunding Finish
$700,00020102013
GNo:G1000045

An Integrated LC-MS-NMR facility for Applications in Proteomics and Organic Chemistry$500,000
Funding Body: ARC (Australian Research Council)

Project Team
Professor Adam McCluskey, Laureate Professor John Aitken, Professor Paul Dastoor, Professor Phillip Robinson, Professor Eileen McLaughlin, Emeritus Professor Geoffrey Lawrance, Professor Marcel Maeder, Professor Hugh Dunstan, Doctor Shaun Roman, Associate Professor Rob Atkin, Doctor Clovia Holdsworth, Doctor Mark Baker, Doctor Nikki Verrills, Professor Gottfried Otting, Associate Professor Brett Nixon, Doctor Xiaojing Zhou, Ms Megan Chircop, Doctor Warwick Belcher
SchemeRole
Linkage Infrastructure Equipment & Facilities (LIEF)Investigator
Total AmountFunding StartFunding Finish
$500,00020102010
GNo:G0190402

Laser microdissection microscopy system for cell and development biology$350,000
Funding Body: ARC (Australian Research Council)

An Integrated LC-MS-NMR facility for Applications in Proteomics and Organic Chemistry$280,000
Funding Body: University of Newcastle

Laser microdissection microscopy system for cell and development biology$215,000
Funding Body: University of Newcastle

Feasibility of Humane Camel Management$130,000
Funding Body: CRC for Invasive Animals

Project Team
Laureate Professor John Aitken, Professor Eileen McLaughlin
SchemeRole
Research GrantInvestigator
Total AmountFunding StartFunding Finish
$130,00020102017
GNo:G1100665

Waters, Ultra high performance liquid chromatography system (nano-Aquity) $30,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Doctor Mark Baker, Laureate Professor John Aitken, Professor Adam McCluskey, Associate Professor Brett Nixon, Professor John Rostas, Professor Eileen McLaughlin
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$30,00020102010
GNo:G1000051

Electron Multiplier Charge-Coupled Device Camera. Hamamatsu EM-CCD Camera C9100-13$29,079
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor Keith Jones, Professor Eileen McLaughlin, Professor Dirk Van Helden, Doctor Rick Thorne
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$29,07920102010
GNo:G1000052

2009 (8 grants)

The role of the Anaphase-Promoting Complex activator Cdh1 in mammalian oocytes and aneuploidy$506,250
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor Keith Jones, Professor Eileen McLaughlin
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$506,25020092011
GNo:G0188850

An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry$495,000
Funding Body: ARC (Australian Research Council)

Characterization of the molecular basis of human sperm-oocyte interaction$474,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Associate Professor Brett Nixon, Professor Eileen McLaughlin, Dr M O'Bryan
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$474,00020092011
GNo:G0188867

RNA binding proteins Musashi: role in foliculogenesis and oocyte development$402,750
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Eileen McLaughlin, Dr Gary Hime
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$402,75020092011
GNo:G0188862

Confocal Laser Scanning Microscopy for Live Cell Imaging$275,000
Funding Body: ARC (Australian Research Council)

Aging eggs: understanding the molecular mechanisms of declining female fertility$79,489
Funding Body: Hunter Medical Research Institute

Project Team
Conjoint Professor Keith Jones, Professor Eileen McLaughlin
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$79,48920092010
GNo:G0189795

An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry$50,000
Funding Body: ARC (Australian Research Council)

LAS-4000 Chemiluminescence imaging system$25,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Eileen McLaughlin, Laureate Professor John Aitken, Professor Peter Lewis, Associate Professor Brett Nixon, Doctor Shaun Roman
SchemeRole
Equipment GrantChief Investigator
Total AmountFunding StartFunding Finish
$25,00020092009
GNo:G0189852

2008 (10 grants)

Centre for Biotechnology and Development$6,420,000
Funding Body: ARC (Australian Research Council)

Project Team
Laureate Professor John Aitken, Dr Gary Hime, Professor M Holland, Professor D Jans, Professor P Koopman, Dr Kate Loveland, Professor Eileen McLaughlin, Dr M O'Bryan, Doctor Shaun Roman, Assoc. Prof A Sinclair
SchemeRole
ARC Centres of ExcellenceInvestigator
Total AmountFunding StartFunding Finish
$6,420,00020082010
GNo:G0188624

Xenobiotics - ocidative stress in the mammalian ovary$362,625
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Eileen McLaughlin, Associate Professor Brett Nixon, Doctor Shaun Roman
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$362,62520082010
GNo:G0187620

Centre for Biotechnology and Development$297,273
Funding Body: NSW Department of State and Regional Development

Project Team
Laureate Professor John Aitken, Dr Gary Hime, Professor M Holland, Professor D Jans, Professor P Koopman, Dr Kate Loveland, Professor Eileen McLaughlin, Dr M O'Bryan, Doctor Shaun Roman, Assoc. Prof A Sinclair
SchemeRole
Centres of Excellence (Partner)Investigator
Total AmountFunding StartFunding Finish
$297,27320082010
GNo:G0189183

Cellular signals controlling oocyte activation$270,000
Funding Body: ARC (Australian Research Council)

Project Team
Professor Eileen McLaughlin, Dr Darryl Russell, Dr Rebecca Robker
SchemeRole
Discovery ProjectsChief Investigator
Total AmountFunding StartFunding Finish
$270,00020082010
GNo:G0187536

CEF Admin Relief McLaughlin$50,000
Funding Body: University of Newcastle

Project Team
Professor Hugh Dunstan, Professor Eileen McLaughlin
SchemeRole
Career Enhancement Fellowship for Academic WomenInvestigator
Total AmountFunding StartFunding Finish
$50,00020082008
GNo:G0189257

Understanding the aetiology of human male infertility: Elucidation of the mechanisms underpinning sperm-egg interaction$21,650
Funding Body: Hunter Medical Research Institute

Project Team
Associate Professor Brett Nixon, Professor Eileen McLaughlin
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$21,65020082008
GNo:G0188465

Characterization of the molecular basis of mouse sperm-oocyte interaction$18,285
Funding Body: University of Newcastle

Project Team
Associate Professor Brett Nixon, Professor Eileen McLaughlin
SchemeRole
Near Miss GrantInvestigator
Total AmountFunding StartFunding Finish
$18,28520082008
GNo:G0188405

Programmed mammalian oocyte activation: the production line model of primordial follicle development$14,700
Funding Body: University of Newcastle

Project Team
Professor Eileen McLaughlin, Conjoint Professor Keith Jones
SchemeRole
Pilot GrantChief Investigator
Total AmountFunding StartFunding Finish
$14,70020082008
GNo:G0189084

Personal career development within the University of Newcastle in 2008$8,000
Funding Body: University of Newcastle

Project Team
Professor Eileen McLaughlin
SchemeRole
Career Enhancement Fellowship for Academic WomenChief Investigator
Total AmountFunding StartFunding Finish
$8,00020082008
GNo:G0188507

41st Annual Meeting of the Society for the Study of Reproduction $2,500
Funding Body: University of Newcastle

Project Team
Professor Eileen McLaughlin
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,50020082008
GNo:G0188937

2007 (9 grants)

FACSAria - Fluorescence activated cell sorter$300,000
Funding Body: Cancer Institute NSW

Project Team
Doctor Nikki Verrills, Conjoint Professor Leonie Ashman, Laureate Professor John Aitken, Professor Eileen McLaughlin, Professor Alistair Sim, Doctor Rick Thorne, Doctor Jennette Sakoff
SchemeRole
Infrastructure GrantsInvestigator
Total AmountFunding StartFunding Finish
$300,00020072007
GNo:G0187666

Biotechnology applications in the veterinary pharmacuetical industry: Pharmacological manipulation of ovarian function in domestic animals$134,998
Funding Body: Pestat Pty Ltd

Project Team
Professor Eileen McLaughlin, Laureate Professor John Aitken
SchemeRole
Linkage Projects Partner fundingChief Investigator
Total AmountFunding StartFunding Finish
$134,99820072010
GNo:G0188204

Centre for Biotechnology and Development.$96,220
Funding Body: NSW Department of State and Regional Development

Project Team
Laureate Professor John Aitken, Dr Kate Loveland, Professor P Koopman, Assoc. Prof A Sinclair, Professor D De Krester, Dr M O'Bryan, Dr Gary Hime, Professor D Jans, Doctor Shaun Roman, Professor Eileen McLaughlin, Professor C Goodnow, Professor M Holland
SchemeRole
Centres of Excellence (Partner)Investigator
Total AmountFunding StartFunding Finish
$96,22020072007
GNo:G0187937

HMRI Contribution toward FACSAria - Fluorescence activated cell sorter$52,000
Funding Body: Hunter Medical Research Institute

Project Team
Doctor Nikki Verrills, Conjoint Professor Leonie Ashman, Laureate Professor John Aitken, Professor Eileen McLaughlin, Professor Alistair Sim, Doctor Rick Thorne, Doctor Jennette Sakoff
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$52,00020072007
GNo:G0188207

High speed/sensitivity CCD camera$30,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Dirk Van Helden, Professor Eileen McLaughlin, Professor Gordon Burns, Doctor Rick Thorne, Dr Marcus Howlett, Doctor Mohammad Imtiaz, Associate Professor Alan Brichta, Professor Robert Callister, Doctor Brett Graham, Associate Professor Derek Laver, Associate Professor Liz Milward, Doctor John Holdsworth
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$30,00020072007
GNo:G0188196

Chemokines and spermatogenesis: roles of SDF-1 and CXCR-4 in the establishment of spermatogenesis$20,000
Funding Body: University of Newcastle

Project Team
Professor Eileen McLaughlin, Doctor Shaun Roman, Associate Professor Brett Nixon
SchemeRole
Near Miss GrantChief Investigator
Total AmountFunding StartFunding Finish
$20,00020072007
GNo:G0187197

Cytokines and Folliculogenesis$20,000
Funding Body: University of Newcastle

Project Team
Professor Eileen McLaughlin
SchemeRole
Near Miss GrantChief Investigator
Total AmountFunding StartFunding Finish
$20,00020072007
GNo:G0187187

Musashi 1 and 2 - role of RNA binding proteins in oocyte maturation$14,550
Funding Body: University of Newcastle

Project Team
Professor Eileen McLaughlin
SchemeRole
Pilot GrantChief Investigator
Total AmountFunding StartFunding Finish
$14,55020072007
GNo:G0186712

2007 SRB Annual Scientific Conference to be held in cnjunction with the ESA, Christchurch Convention Centre, New Zealand, 2/9/2007 - 5/9/2007$2,099
Funding Body: University of Newcastle

Project Team
Professor Eileen McLaughlin
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,09920072007
GNo:G0188058

2006 (4 grants)

PRC - Priority Research Centre for Reproductive Science$544,282
Funding Body: University of Newcastle

Project Team
Laureate Professor John Aitken, Professor Roger Smith, Professor Eileen McLaughlin, Associate Professor Brett Nixon, Doctor Shaun Roman, Conjoint Associate Professor Vicki Clifton, Conjoint Professor Warwick Giles, Associate Professor Jon Hirst, Conjoint Associate Professor Rick Nicholson, Conjoint Professor Ian Symonds
SchemeRole
Priority Research CentreInvestigator
Total AmountFunding StartFunding Finish
$544,28220062013
GNo:G0186945

Environmental impacts on female fertility and the menopause$17,273
Funding Body: Hunter Medical Research Institute

Project Team
Professor Eileen McLaughlin, Laureate Professor John Aitken, Doctor Shaun Roman
SchemeRole
Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$17,27320062006
GNo:G0186620

Cytokine signalling pathway and ovarian folliculogenesis$10,000
Funding Body: University of Newcastle

Project Team
Professor Eileen McLaughlin, Dr Darryl Russell
SchemeRole
Near Miss GrantChief Investigator
Total AmountFunding StartFunding Finish
$10,00020062006
GNo:G0186066

American Society of Andrology 31st Annual Conference, April 8 -11, 2006$1,500
Funding Body: University of Newcastle

Project Team
Professor Eileen McLaughlin
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$1,50020062006
GNo:G0186466

2005 (3 grants)

High throughput proteomics - Thermo Finnigan ProteomeX LCQ Integrated Proteomicis Workstation$207,189
Funding Body: ARC (Australian Research Council)

SOCS-4 - modulation of cytokine and growth factor signalling in the mammalian ovary$10,000
Funding Body: University of Newcastle

Project Team
Professor Eileen McLaughlin, Conjoint Associate Professor Renate Griffith
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$10,00020052005
GNo:G0184635

Oolemmal receptors - the role of the tetraspanin CD151 in sperm-egg fusion$7,537
Funding Body: University of Newcastle

Project Team
Professor Eileen McLaughlin, Conjoint Professor Leonie Ashman
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$7,53720052005
GNo:G0184625

2004 (6 grants)

Multifunctional confocal laser scanning microscope with time resolved and two photon imaging and fluorescence correlation capabilities $579,230
Funding Body: Australian Research Council

SchemeRole
Chief Investigator
Total AmountFunding StartFunding Finish
$579,23020042004
GNo:15155235

Biotechnology applications in the veterinary pharmaceutical industry: Pharmacological manipulation of ovarian function in domestic animals$465,000
Funding Body: ARC (Australian Research Council)

Project Team
Professor Eileen McLaughlin, Laureate Professor John Aitken, Dr J O'Brien
SchemeRole
Linkage ProjectsChief Investigator
Total AmountFunding StartFunding Finish
$465,00020042006
GNo:G0183627

Biotechnology applications in the veterinary pharmacuetical industry: Pharmacological manipulation of ovarian function in domestic animals$298,368
Funding Body: Jurox

Project Team
Professor Eileen McLaughlin, Laureate Professor John Aitken, Dr J O'Brien
SchemeRole
Linkage Projects Partner fundingChief Investigator
Total AmountFunding StartFunding Finish
$298,36820042006
GNo:G0183816

High-Speed Confocal Microscope Live Cell Recording System$274,692
Funding Body: ARC (Australian Research Council)

Project Team
Professor Dirk Van Helden, Laureate Professor John Aitken, Professor Eileen McLaughlin, Associate Professor Alan Brichta, Associate Professor J Keast, Dr J Brock, Dr S Head
SchemeRole
Linkage Infrastructure Equipment & Facilities (LIEF)Investigator
Total AmountFunding StartFunding Finish
$274,69220042004
GNo:G0183031

High-speed Confocal Microscope Live Cell Recording System$30,000
Funding Body: University of New South Wales

Project Team
Professor Dirk Van Helden, Associate Professor J Keast, Laureate Professor John Aitken, Dr J Brock, Professor Eileen McLaughlin, Dr S Head, Associate Professor Alan Brichta
SchemeRole
Linkage Infrastructure Equipment & Facilities (LIEF) Partner fundingInvestigator
Total AmountFunding StartFunding Finish
$30,00020042004
GNo:G0183841

Activation of the mammalian primordial follicle.$8,500
Funding Body: University of Newcastle

Project Team
Professor Eileen McLaughlin
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$8,50020042004
GNo:G0183443

2003 (4 grants)

Centre for Biotechnology and Development.$9,458,900
Funding Body: ARC (Australian Research Council)

Project Team
Laureate Professor John Aitken, Dr Kate Loveland, Professor P Koopman, Assoc. Prof A Sinclair, Professor D De Krester, Dr M O'Bryan, Dr Gary Hime, Professor D Jans, Doctor Shaun Roman, Professor Eileen McLaughlin, Professor C Goodnow, Professor M Holland
SchemeRole
ARC Centres of ExcellenceInvestigator
Total AmountFunding StartFunding Finish
$9,458,90020032007
GNo:G0182214

The role of cytokines in the activation of the ovarian follicle.$17,000
Funding Body: Hunter Medical Research Institute

Project Team
Professor Eileen McLaughlin, Laureate Professor John Aitken
SchemeRole
Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$17,00020032003
GNo:G0182197

Oolemmal Proteomics - identification of oocyte cell surface protein complexes involved in sperm-egg interaction$12,000
Funding Body: University of Newcastle

Project Team
Professor Eileen McLaughlin, Laureate Professor John Aitken
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$12,00020032003
GNo:G0182320

Profiling germ cell gene expression during spermatogonial differentiation$5,000
Funding Body: University of Newcastle

Project Team
Doctor Shaun Roman, Professor Eileen McLaughlin
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$5,00020032003
GNo:G0182402

2002 (1 grants)

Oocyte selection in the female germ line - survival of the fittest?$12,000
Funding Body: University of Newcastle

Project Team
Professor Eileen McLaughlin
SchemeRole
New Staff GrantChief Investigator
Total AmountFunding StartFunding Finish
$12,00020022002
GNo:G0182024
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Research Supervision

Number of current supervisions9
Total current UoN PhD EFTSL3.55

For supervisions undertaken at an institution other that the University of Newcastle, details are shown in italics, and the institution name is listed below the program name.

Current Supervision

CommencedProposed
Completion
ProgramSupervisor TypeResearch Title
20132017PhD (Biological Sciences)Principal SupervisorPhage Peptides Fertility Control
20132017PhD (Biological Sciences)Principal SupervisorThe Impact of Maternal Ageing and Chemotoxicants on Female Fertility
20122016PhD (Biological Sciences)Principal SupervisorInvestigation into the Mechanisms Controlling Mammalian Spermatogenesis and Folliculogenesis: A Focus on the Essential Roles of the Musashi Family of RNA Binding Proteins
20122016PhD (Biological Sciences)Co-SupervisorHedgehog Signaling Pathway Inhibitors as Cancer Suppressing Agents
20112016PhD (Biological Sciences)Principal SupervisorGamete-Specific Knockout of Fizzy-Related 1 to Examine its Meiotic Role in Spermatozoa
20102014PhD (Human Physiology)Co-SupervisorElucidation of Higher Meiotic Errors on Oocyte from Advanced Maternat Ages through Kinetochore Tracking
20072007Honours Biol Sc Not Elsewhere Classifd
University of Newcastle
Principal SupervisorMusashi 1 and 2 RNA binding proteins role in mammalian folliculogenesis
20072007Honours Biol Sc Not Elsewhere Classifd
University of Newcastle
Principal SupervisorOxidiative stress and Folliculogenesis
20072007Honours Biol Sc Not Elsewhere Classifd
University of Newcastle
Co-SupervisorChemokines and spermatogenesis

Past Supervision

YearProgramSupervisor TypeResearch Title
2013PhD (Biological Sciences)Co-SupervisorNew Insights into the Molecular Basis of Human Sperm-Egg Interaction
2013PhD (Biological Sciences)Principal SupervisorRegulation of the Transition from Gonocytes to Spermatogonia
2013PhD (Biological Sciences)Principal SupervisorTranslational Control of Mouse Folliculogenesis and Oocyte Development
2012PhD (Biological Sciences)Principal SupervisorXenobiotics; Effects on Female Fertility
2008PhD (Biological Sciences)Principal SupervisorOolemmal Proteomics: Identification of Oocyte Cell Surface Protein Complexes Involved in Murine Fertilisation
2006Honours Biol Sc Not Elsewhere Classifd
University of Newcastle
Principal SupervisorNon genomic action of progesterone in human spermatozoa
2006Honours Biol Sc Not Elsewhere Classifd
University of Newcastle
Co-SupervisorXenobiotics Effects on mammalian folliculogenesis
2006PhD (Biological Sciences)Principal SupervisorGene Expression During Development of the Mammalian Ovarian Primordial Follicle
2006PhD (Biological Sciences)Principal SupervisorNon-Surgical Sterilisation of Female Domesticated Animals
2005Honours Biol Sc Not Elsewhere Classifd
University of Newcastle
Principal SupervisorSupressors of Cytokine Signalling
2005PHD Biol Sc Not Elsewhere Classifd
Australian National University
Consultant SupervisorThe role of Kit Ligand in primordial follicle activation in the juvenile rabbit ovary
2005PhD (Biological Sciences)Co-SupervisorThe Molecular Basis of Sperm-Oocyte Interaction in the Mouse
2004Masters Biol Sc Not Elsewhere Classifd
University of Newcastle
Co-SupervisorA novel GTPase activating protein RhGAPs in the male gamete
2003Honours Biol Sc Not Elsewhere Classifd
University of Newcastle
Co-SupervisorCharacterisation of the sperm progesterone receptor
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Professor Eileen McLaughlin

Work Phone(02) 4921 2005 PVC Unit (02) 4921 5708 Biological Sciences
Cell / Mobile Phone0437 091293
Fax(02) 4921 7949 PVC Unit (02) 4921 6308 Biological Sciences
Email
PositionDeputy Head of Faculty
PRC in Chemical Biology PRC in Reproductive Science
School of Environmental and Life Sciences
Faculty of Science and Information Technology
The University of Newcastle, Australia
Focus AreaBiological Sciences
Office
V201B PVC Unit LS4 38 Biological Sciences,
Life Sciences,
Callaghan
University Drive
Callaghan NSW 2308
Australia
URL:www.newcastle.edu.au/profile/eileen-mclaughlin