Dr Carmel Loughland

Dr Carmel Loughland

Associate Professor

School of Medicine and Public Health (Public Health)

Career Summary

Biography

Associate Professor Carmel Loughland is a member of the Priority Centre for Translational Neuroscience and Mental Health, and a academic within the Faculty of Medicine and Population Health, University of Newcastle. A/Professor Loughland is also a senior psychologist with several years practical experience as a registered psychologist and is authorised to supervise intern and registered psychologists. She is also a registered Justice of the Peace. A/Professor Loughland obtained her Ph.D from the University of Sydney in 2002. Her research focuses on visuo-cognition deficits, particularly face processing disturbances, in people with schizophrenia and other clinical disorders (i.e., affective disorder, borderline personality disorder, psychopathy). In 2002, she established an eye tracking laboratory purpose built for visual scanpath research at the McAuley Centre, Mater Hospital, Newcastle and has been successful in securing a number of research grants as chief investigator to pursue her research, including the prestigious US NARSAD Young Investigator Award and the Hunter Medical Research Institute (HMRI) Early Career Researcher Award.

Research Expertise
A/Prof. Loughland is an established researcher with a strong track record investigating visuo-cognitive deficits in people with schizophrenia, particularly face emotion processing deficits, and developing remediation programs to reduce the impact of deficits on people's interpersonal and social functioning. A/Prof. Loughland has extended this research to examine how mothers with mental illness process infant face emotion to investigate the impact of these on attachment and child mental health and wellbeing. In addition to this research, A/Prof. Loughland has been involved in the development and management of a number of biobank facilities including the Australian Schizophrenia Research Biobank (ASRB) which holds clinical neuropsychological, fMRI/DTI and genetic data collected from volunteers with schizophrenia and matched controls. This facility has supported over 800 schizophrenia related projects and helps raise awareness about the disorder within the community through research participation and information dissemination. More recently, A/Prof. Loughland and collaborators have developed a communication skills training package called ComPsych to provide core communication skills training to mental health professional for use in psychiatric care. Research is currently being undertaken to evaluate the utility and validity of the ComPsych program in clinical settings with the aim of improving practitioner-patient outcomes for people with a mental illness. 

Teaching Expertise
A/Prof. Loughland supervisors students in medicine and psychology, and has provided courses in personality and individual differences, clinical assessment and data management, and abnormal psychology. A/Prof. Loughland's RHD students are currently undertaking research in face processing in people with schizophrenia, psychopathy, post-natal depression,and borderline personality disorder. Students are also working in studies investigating parenting and infant face perception, the perception and experiences of medical research volunteers, and the evaluation of communication skills training programs in psychiatry. 

Administrative Expertise
A/Prof Loughland is a senior academic with several years experience managing people.

Collaborations
Dr Loughland is a member of several research teams. These include the following: Priority Centre for Translational Neuroscience and Mental Health, Centre for Rural and Remote Research, Schizophrenia Research Insititute (SRI) - Australian Schizophrenia Research Bank (ASRB), Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium.


Qualifications

  • PhD (Science), University of Sydney
  • Bachelor of Arts (Psychology) Honours, Unknown

Keywords

  • Abnormal Psychology
  • Biobanking
  • Communication
  • Eye tracking
  • Face perception and processing
  • Mental Health
  • Mental ill-health
  • Parenting
  • Personality and Individual Differences
  • Rehabilitation
  • Schizophrenia
  • Social cognition

Languages

  • English (Mother)

Fields of Research

Code Description Percentage
170199 Psychology not elsewhere classified 25
110319 Psychiatry (incl. Psychotherapy) 25
111714 Mental Health 50

Professional Experience

Academic appointment

Dates Title Organisation / Department
1/07/2012 -  Associate Professor

Carmel is a senior registered psychologist with several years clinical experience and currently works in private practice one day per week. She obtained her Ph.D from the University of Sydney in 2002. Her research focus is on social cognition deficits, particularly face and emotion processing disturbances, in people with mental illness and psychological disorder (i.e., schizophrenia, affective disorder, psychopathy, personality disorder). More recently this research has focused on mother-infant relationships in women with post-natal depression to examine visuo-cognitive disturbances in parenting impacting attachment, emotional availability and child mental health and wellbeing. Carmel is a contributor to an NHMRC working group on parenting and child mental health and welbeing. In 2002, she established an eye tracking laboratory purpose built for visual scanpath research at the Centre for Brain and Mental Health Research, Newcastle, and has been successful in securing a number of research grants as chief investigator to pursue her projects. These included the prestigious US NARSAD Young Investigator Award, Hunter Medical Research Institute (HMRI) Early Career Researcher Award, and other competitive project grant funding from HMRI, Schizophrenia Research Insititute (SRI) and NSW Health, Education and Training Institute (HETI). Carmel has also secured donations for this research from community groups such as Lions and Tour Des Femmes Women Cyclists for Research.

Carmel has an extensive track record in schizophrenia data-biobank development. In 1997, Carmel established the Schizophrenia Research Institute’s Register and is a founding member of the HMRI Volunteer Research Register established in 2003. Following on the success of the Register, Carmel and collaborators obtained funding (The Percy Baxter Charitable Foundation; Australian Rotary Health Research Fund Research Grant) to establish in 2003 the Hunter DNA Biobank for Schizophrenia and Allied Disorders to store genetic material for mental health research.  In 2006, Carmel and collaborators established the Australian Schizophrenia Research Biobank (ASRB), which provides a national facility for genetic research into schizophrenia. NHMRC Enabling Grant (ID386500 - $1.75 M) and Pratt Foundation ($1.4M) funding was successfully obtained to establish the ASRB,which is a national not-for-profit resource that supports a wide spectrum of Australian and international schizophrenia research projects. Carmel managed the ASRB from 2006-2015 along with a team of 20 clinical and technical employees involved in patient recruitment, clinical and neuropsychological assessment, sMRI and DTI brain scanning, and genetic sample collection in people with schizophrenia and healthy controls. This unique resource has drawn significant national and international scientific attention and not only makes a valuable contribution to Australian medical research, but to the broader community through the provision of educational information. Collectively, these resources engage the community in medical research by allowing volunteers to participate in research projects in their local area. Scientists are able to access these resources to recruit participants for their projects. To date, these resources have supported over 800 research projects, and in the process reduced research costs and inform the public about mental health and medical research outcomes. 

More recently, Carmel and collaborators have developed a communication skills training program for psychiatry (ComPsych) to improve practitioner-patient communication and foster better clinical outcomes for patients with schizophrenia by better informing them about diagnosis and treatment. Outcomes from this research include $37,000 in funding, 7 publications, and 22 published conference abstracts.

In 2015, Carmel became Clinical Adviser for the Pathways to Community Living Initiative (PCLI) with NSW Ministry of Health in partnership with Hunter New England Mental Health Services. The PCLI will assist people with enduring and severe mental ill-health who are currently long-stay patients (>365 days hospitalisation) experience better quality of life and improved social outcomes through transition to community living, where appropriate. Carmel will oversee the research, analysis, evaluation and dissemination of outcomes from the project.

Carmel has appeared on several national television and radio programs to discuss her research including ‘Sunrise’, ‘Foxtel News’ and current affairs programs such as ‘Today Extra’, and participated in the 2009 ‘Medical Marvels’ television series. Several print media have published articles about her research (International Innovations, Hunter Lifestyle Magazine, Sun-Herald Body and Soul Magazine, Newcastle Herald).


Faculty of Health, University of Newcastle
Australia

Awards

Award

Year Award
2004 NARSAD Young Investigator Award
National Alliance for Research on Schizophrenia and Depression
1990 Medal of Excellence in Welfare Studies
NSW College of TAFE, Blacktown

Prize

Year Award
2013 2013 University Publication Prize, Faculty of Medicine ($1,000)
Faculty of Health, University of Newcastle
2002 Research Publication Prize
The University of Sydney

Research Award

Year Award
2006 HMRI PULSE Early Career Research Award
Hunter Medical Research Institute (HMRI)

Invitations

Panel Participant

Year Title / Rationale
2008 Emotion, Cognition and Psychopathology Symposium

Speaker

Year Title / Rationale
2013 Communicating ‘Bad’ Diagnostic News in Psychiatry
2008 Emotion, Cognition and Psychopathology
2008 Facing the challenges: Visuo-cognitive and emotion processing defitcits in schizophrenia.
2006 Cannabis and psychosis: From neuroscience to clinical intervention.
2006 Psychopathologies of Social Cognition Symposium: Linking neural, cognitive and clinical perspectives.
2003 Face processing deficits in schizophrenia: what can we learn from visual scanpath analysis?

Thesis Examinations

Year Level Discipline Thesis
2011 Masters Health Facial emotion recognition in schizophrenia and its relationship to trauma and social cognition.
2011 Masters Health Early psychosis pathways to care and clinical outcomes in rural communities.
2010 PHD Health Face processing in schizophrenia: An investigation of configural processing and the relationship with facial emotion processing and neurocognition.
2010 Masters Health Subjective measurement of treatment outcomes for people with schizophrenia on antipsychotics: description and application in an Australian sample.
2009 PHD Health A-typical viewing behaviour in schizophrenia
2003 PHD Health Modelling face processing using EEG in people with schizophrenia

Grant Reviews

Year Grant Amount
2009 Biomedical and Therapeutic Research Committee, Chief Scientist Office, National Health Service, Scotland
International - Competitive - 3IFA, International - Competitive - 3IFA
$600,000
2007 Biomedical and Therapeutic Research Committee, Chief Scientist Office, National Health Service, Scotland
International - Competitive - 3IFA, International - Competitive - 3IFA
$500,000
2005 National Health and Medical Research Committee (NHMRC) - Project Grants
Aust Competitive - Commonwealth - 1CS, Aust Competitive - Commonwealth - 1CS
$800,000

Prestigious works

Year Commenced Year Finished Prestigious Work Role
2006 2015 Australian Schizophrenia Research BioBank (ASRB) www.schizophreniaresearch.org.au/bank Constructor
2005 2020 HMRI Volunteer Register https://hmri.org.au/support/volunteer/research-register/ Contributor
2003 2006 Hunter DNA Bank for Schizophrenia Research and Allied Disorders www.schizophreniaresearch.org Contributor
1997 2006 Schizophrenia Research Register www.schizophreniaresearch.org.au/...in-research/schizophrenia-register/ Cached Similar Constructor
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Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Chapter (1 outputs)

Year Citation Altmetrics Link
2013 Schofield PW, Moore T, Loughland C, Lechner-Scott J, 'The Audio Recorded Cognitive Screen (ARCS): A flexible and versatile instrument for clinic or research', Screening Tests, Nova Science, Hauppaugue, NY 111-126 (2013) [B1]
Co-authors Peter Schofield

Journal article (46 outputs)

Year Citation Altmetrics Link
2016 Mehta D, Tropf FC, Gratten J, Bakshi A, Zhu Z, Bacanu SA, et al., 'Evidence for Genetic Overlap Between Schizophrenia and Age at First Birth in Women.', JAMA Psychiatry, 73 497-505 (2016)
DOI 10.1001/jamapsychiatry.2016.0129
Co-authors Murray Cairns, Pat Michie, Frans Henskens, Ulrich Schall, Paul Tooney
2016 Franke B, Stein JL, Ripke S, Anttila V, Hibar DP, van Hulzen KJE, et al., 'Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept', Nature Neuroscience, (2016)
DOI 10.1038/nn.4228
Co-authors Pat Michie, Paul Tooney, Ulrich Schall, Frans Henskens, Rodney Scott
2015 Outram S, Harris G, Kelly B, Bylund CL, Cohen M, Landa Y, et al., ''We didn't have a clue': Family caregivers' experiences of the communication of a diagnosis of schizophrenia', International Journal of Social Psychiatry, 61 10-16 (2015) [C1]
DOI 10.1177/0020764014535751
Citations Scopus - 4Web of Science - 2
Co-authors Brian Kelly, Sue Outram
2015 Ditton-Phare P, Halpin S, Sandhu H, Kelly B, Vamos M, Outram S, et al., 'Communication skills in psychiatry training', AUSTRALASIAN PSYCHIATRY, 23 429-431 (2015) [C3]
DOI 10.1177/1039856215590026
Co-authors Brian Kelly, Sue Outram, Sean Halpin
2015 Outram S, Harris G, Kelly B, Cohen M, Bylund CL, Landa Y, et al., 'Contextual barriers to discussing a schizophrenia diagnosis with patients and families: Need for leadership and teamwork training in psychiatry', Academic Psychiatry, 39 174-180 (2015) [C1]

© 2014 Academic Psychiatry. Objective: This research sought to gain insight into the processes used by clinicians to discuss a schizophrenia diagnosis with patients/families, wit... [more]

© 2014 Academic Psychiatry. Objective: This research sought to gain insight into the processes used by clinicians to discuss a schizophrenia diagnosis with patients/families, with the aim of informing the development of a communications skills training program. Methods: A generic qualitative methodological approach was used. Sixteen mental health clinicians were recruited. Semi-structured individual interviews were used to explore their perceptions and experiences communicating a schizophrenia diagnosis. Interviews were recorded, transcribed, and thematic analysis undertaken. Results: There were five key themes relating to the process of communication about a diagnosis of schizophrenia: (1) orientation to patient care, (2) planning of communication, (3) the impact of team leadership and inter/intra-professional functioning on communication tasks, (4) the roles of different clinicians in communicating about diagnosis and treatment, and (5) time and resource deficiencies. Despite expressing care and concern for vulnerable patients and embracing the concept of multidisciplinary teams, communicating diagnostic information to patients and families was generally unplanned for, with little consistency regarding leadership approaches, or how the team communicated diagnostic information to the patient and family. This contributed to tensions between different team members. Conclusion: The findings demonstrated a number of issues compromising good communication around a schizophrenia diagnosis, both in terms of clinician skill and clinical context, and support the importance of education and training for all members of the multidisciplinary team about their role in the communication process.

DOI 10.1007/s40596-014-0226-4
Citations Scopus - 1Web of Science - 2
Co-authors Sue Outram, Brian Kelly
2015 Loughland C, Kelly B, Ditton-Phare P, Sandhu H, Vamos M, Outram S, Levin T, 'Improving clinician competency in communication about schizophrenia: A pilot educational program for psychiatry trainees', Academic Psychiatry, 39 160-164 (2015) [C1]

© 2014 Academic Psychiatry. Objective: Important gaps are observed in clinicians' communication with patients and families about psychiatric disorders such as schizophrenia. Comm... [more]

© 2014 Academic Psychiatry. Objective: Important gaps are observed in clinicians' communication with patients and families about psychiatric disorders such as schizophrenia. Communication skills can be taught, and models for education in these skills have been developed in other fields of medicine, such as oncology, providing a framework for training communication skills relevant to psychiatric practice. This study evaluated a pilot communication skills education program for psychiatry trainees, focusing on discussing schizophrenia diagnosis and prognosis. Method: Communication skills training modules were developed based on an existing theoretical framework (ComSkil), adapted for discussing a schizophrenia diagnosis and prognosis. Pre-post training rating of self-reported confidence in a range of communication tasks was obtained, along with trainee views on the training methods. Results: Thirty-eight participants completed the training. Significant improvements in confidence were reported post training for discussing schizophrenia prognosis, including an increased capacity to critically evaluate their own communication skills. Participants reported high levels of satisfaction with the program. Conclusion: This preliminary study provides support for the translation of a well-established educational model to psychiatric training addressing core clinical communication tasks and provides the foundation for the development of a more comprehensive evaluation and an extended curriculum regarding other aspects of care for patients with schizophrenia: ongoing management and recovery, dealing with conflict, and conducting a family interview.

DOI 10.1007/s40596-014-0195-7
Citations Scopus - 1Web of Science - 2
Co-authors Sue Outram, Brian Kelly
2015 Bulik-Sullivan B, Loh PR, Finucane HK, Ripke S, Yang J, Patterson N, et al., 'LD score regression distinguishes confounding from polygenicity in genome-wide association studies', Nature Genetics, 47 291-295 (2015) [C1]

Both polygenicity (many small genetic effects) and confounding biases, such as cryptic relatedness and population stratification, can yield an inflated distribution of test statis... [more]

Both polygenicity (many small genetic effects) and confounding biases, such as cryptic relatedness and population stratification, can yield an inflated distribution of test statistics in genome-wide association studies (GWAS). However, current methods cannot distinguish between inflation from a true polygenic signal and bias. We have developed an approach, LD Score regression, that quantifies the contribution of each by examining the relationship between test statistics and linkage disequilibrium (LD). The LD Score regression intercept can be used to estimate a more powerful and accurate correction factor than genomic control. We find strong evidence that polygenicity accounts for the majority of the inflation in test statistics in many GWAS of large sample size.

DOI 10.1038/ng.3211
Citations Scopus - 38Web of Science - 10
Co-authors Frans Henskens, Murray Cairns, Ulrich Schall, Paul Tooney, Brian Kelly, Pat Michie, Rodney Scott
2015 Loughland C, Cheng K, Harris G, Kelly B, Cohen M, Sandhu H, et al., 'Communication of a schizophrenia diagnosis: A qualitative study of patients' perspectives.', Int J Soc Psychiatry, 61 729-734 (2015) [C1]
DOI 10.1177/0020764015576814
Co-authors Sue Outram, Brian Kelly
2015 Garrison JR, Fernyhough C, McCarthy-Jones S, Haggard M, Carr V, Schall U, et al., 'Paracingulate sulcus morphology is associated with hallucinations in the human brain', Nature Communications, 6 (2015) [C1]
DOI 10.1038/ncomms9956
Co-authors Frans Henskens, Rodney Scott, Ulrich Schall, Pat Michie
2015 Vilhjálmsson BJ, Yang J, Finucane HK, Gusev A, Lindström S, Ripke S, et al., 'Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores', American Journal of Human Genetics, 97 576-592 (2015) [C1]

© 2015 The American Society of Human Genetics. All rights reserved. Polygenic risk scores have shown great promise in predicting complex disease risk and will become more accurat... [more]

© 2015 The American Society of Human Genetics. All rights reserved. Polygenic risk scores have shown great promise in predicting complex disease risk and will become more accurate as training sample sizes increase. The standard approach for calculating risk scores involves linkage disequilibrium (LD)-based marker pruning and applying a p value threshold to association statistics, but this discards information and can reduce predictive accuracy. We introduce LDpred, a method that infers the posterior mean effect size of each marker by using a prior on effect sizes and LD information from an external reference panel. Theory and simulations show that LDpred outperforms the approach of pruning followed by thresholding, particularly at large sample sizes. Accordingly, predicted R2 increased from 20.1% to 25.3% in a large schizophrenia dataset and from 9.8% to 12.0% in a large multiple sclerosis dataset. A similar relative improvement in accuracy was observed for three additional large disease datasets and for non-European schizophrenia samples. The advantage of LDpred over existing methods will grow as sample sizes increase.

DOI 10.1016/j.ajhg.2015.09.001
Citations Scopus - 1
Co-authors Brian Kelly, Frans Henskens, Rodney Scott, Pat Michie, Ulrich Schall, Paul Tooney
2015 Gelder BM, Loughland CM, Carr VJ, Schofield PW, 'Application of the Audio Recorded Cognitive Screen and its relation to functioning in schizophrenia', Acta Neuropsychiatrica, 27 279-290 (2015) [C1]
DOI 10.1017/neu.2015.19
Co-authors Peter Schofield
2015 Finucane HK, Bulik-Sullivan B, Gusev A, Trynka G, Reshef Y, Loh P-R, et al., 'Partitioning heritability by functional annotation using genome-wide association summary statistics', Nature Genetics, 47 1228-1235 (2015) [C1]
DOI 10.1038/ng.3404
Co-authors Pat Michie, Rodney Scott, Frans Henskens, Ulrich Schall, Paul Tooney
2015 Loh P-R, Bhatia G, Gusev A, Finucane HK, Bulik-Sullivan BK, Pollack SJ, et al., 'Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis', Nature Genetics, 47 1385-1392 (2015) [C1]
DOI 10.1038/ng.3431
Co-authors Ulrich Schall, Frans Henskens, Rodney Scott, Pat Michie, Paul Tooney
2015 Ingason A, Giegling I, Hartmann AM, Genius J, Konte B, Friedl M, et al., 'Expression analysis in a rat psychosis model identifies novel candidate genes validated in a large case¿control sample of schizophrenia', Translational Psychiatry, 5 e656-e656 (2015) [C1]
DOI 10.1038/tp.2015.151
Co-authors Murray Cairns, Paul Tooney, Rodney Scott, Pat Michie, Brian Kelly, Frans Henskens, Ulrich Schall
2014 Gusev A, Lee SH, Trynka G, Finucane H, Vilhjálmsson BJ, Xu H, et al., 'Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases', The American Journal of Human Genetics, 95 535-552 (2014) [C1]
DOI 10.1016/j.ajhg.2014.10.004
Citations Scopus - 51Web of Science - 24
Co-authors Paul Tooney, Frans Henskens, Ulrich Schall
2014 Ripke S, Neale BM, Corvin A, Walters JTR, Farh KH, Holmans PA, et al., 'Biological insights from 108 schizophrenia-associated genetic loci', Nature, 511 421-427 (2014) [C1]

Schizophrenia is a highly heritable disorder. Genetic risk is conferred by a large number of alleles, including common alleles of small effect that might be detected by genome-wid... [more]

Schizophrenia is a highly heritable disorder. Genetic risk is conferred by a large number of alleles, including common alleles of small effect that might be detected by genome-wide association studies. Here we report a multi-stage schizophrenia genome-wide association study of up to 36,989 cases and 113,075 controls. We identify 128 independent associations spanning 108 conservatively defined loci that meet genome-wide significance, 83 of which have not been previously reported. Associations were enriched among genes expressed in brain, providing biological plausibility for the findings. Many findings have the potential to provide entirely new insights into aetiology, but associations at DRD2 and several genes involved in glutamatergic neurotransmission highlight molecules of known and potential therapeutic relevance to schizophrenia, and are consistent with leading pathophysiological hypotheses. Independent of genes expressed in brain, associations were enriched among genes expressed in tissues that have important roles in immunity, providing support for the speculated link between the immune system and schizophrenia. © 2014 Macmillan Publishers Limited. All rights reserved.

DOI 10.1038/nature13595
Citations Scopus - 638Web of Science - 228
Co-authors Rodney Scott, Ulrich Schall, Pat Michie, Frans Henskens
2014 Elliot R-L, Campbell L, Hunter M, Cooper G, Melville J, McCabe K, et al., 'WHEN I LOOK INTO MY BABY'S EYES... INFANT EMOTION RECOGNITION BY MOTHERS WITH BORDERLINE PERSONALITY DISORDER', INFANT MENTAL HEALTH JOURNAL, 35 21-32 (2014) [C1]
DOI 10.1002/imhj.21426
Citations Scopus - 4Web of Science - 2
Co-authors Mick Hunter, Linda E Campbell
2014 Outram S, Harris G, Kelly B, Cohen M, Sandhu H, Vamos M, et al., 'Communicating a Schizophrenia Diagnosis to Patients and Families: A Qualitative Study of Mental Health Clinicians', PSYCHIATRIC SERVICES, 65 551-554 (2014) [C1]
DOI 10.1176/appi.ps.201300202
Citations Scopus - 4Web of Science - 3
Co-authors Brian Kelly, Sue Outram
2014 McCabe KL, Atkinson RJ, Cooper G, Melville JL, Harris J, Schall U, et al., 'Pre-pulse inhibition and antisaccade performance indicate impaired attention modulation of cognitive inhibition in 22q11.2 deletion syndrome (22q11DS)', Journal of Neurodevelopmental Disorders, 6 (2014) [C1]

© 2014 McCabe et al.; licensee BioMed Central Ltd. Background: 22q11.2 deletion syndrome (22q11DS) is associated with a number of physical anomalies and neuropsychological defici... [more]

© 2014 McCabe et al.; licensee BioMed Central Ltd. Background: 22q11.2 deletion syndrome (22q11DS) is associated with a number of physical anomalies and neuropsychological deficits including impairments in executive and sensorimotor function. It is estimated that 25% of children with 22q11DS will develop schizophrenia and other psychotic disorders later in life. Evidence of genetic transmission of information processing deficits in schizophrenia suggests performance in 22q11DS individuals will enhance understanding of the neurobiological and genetic substrates associated with information processing. In this report, we examine information processing in 22q11DS using measures of startle eyeblink modification and antisaccade inhibition to explore similarities with schizophrenia and associations with neurocognitive performance. Methods: Startle modification (passive and active tasks; 120- and 480-ms pre-pulse intervals) and antisaccade inhibition were measured in 25 individuals with genetically confirmed 22q11DS and 30 healthy control subjects. Results: Individuals with 22q1 1DS exhibited increased antisaccade error as well as some evidence (trend-level effect) of impaired sensorimotor gating during the active condition, suggesting a dysfunction in controlled attentional processing, rather than a pre-attentive dysfunction using this paradigm. Conclusions: The findings from the present study show similarities with previous studies in clinical populations associated with 22q11DS such as schizophrenia that may indicate shared dysfunction of inhibition pathways in these groups.

DOI 10.1186/1866-1955-6-38
Citations Scopus - 4Web of Science - 1
Co-authors Renate Thienel, Linda E Campbell, Ulrich Schall
2013 Terwisscha van Scheltinga AF, Bakker SC, van Haren NEM, Derks EM, Buizer-Voskamp JE, Boos HBM, et al., 'Genetic Schizophrenia Risk Variants Jointly Modulate Total Brain and White Matter Volume', Biological Psychiatry, 73 525-531 (2013) [C1]
DOI 10.1016/j.biopsych.2012.08.017
Citations Scopus - 29
Co-authors Pat Michie, Frans Henskens, Rodney Scott, Ulrich Schall
2013 Van Scheltinga AFT, Bakker SC, Van Haren NEM, Derks EM, Buizer-Voskamp JE, Cahn W, et al., 'Schizophrenia genetic variants are not associated with intelligence', Psychological Medicine, 43 2563-2570 (2013) [C1]

Background Schizophrenia is associated with lower pre-morbid intelligence (IQ) in addition to (pre-morbid) cognitive decline. Both schizophrenia and IQ are highly heritable traits... [more]

Background Schizophrenia is associated with lower pre-morbid intelligence (IQ) in addition to (pre-morbid) cognitive decline. Both schizophrenia and IQ are highly heritable traits. Therefore, we hypothesized that genetic variants associated with schizophrenia, including copy number variants (CNVs) and a polygenic schizophrenia (risk) score (PSS), may influence intelligence. Method IQ was estimated with the Wechsler Adult Intelligence Scale (WAIS). CNVs were determined from single nucleotide polymorphism (SNP) data using the QuantiSNP and PennCNV algorithms. For the PSS, odds ratios for genome-wide SNP data were calculated in a sample collected by the Psychiatric Genome-Wide Association Study (GWAS) Consortium (8690 schizophrenia patients and 11 831 controls). These were used to calculate individual PSSs in our independent sample of 350 schizophrenia patients and 322 healthy controls. Results Although significantly more genes were disrupted by deletions in schizophrenia patients compared to controls (p = 0.009), there was no effect of CNV measures on IQ. The PSS was associated with disease status (R 2 = 0.055, p = 2.1 × 10 -7) and with IQ in the entire sample (R 2 = 0.018, p = 0.0008) but the effect on IQ disappeared after correction for disease status. Conclusions Our data suggest that rare and common schizophrenia-associated variants do not explain the variation in IQ in healthy subjects or in schizophrenia patients. Thus, reductions in IQ in schizophrenia patients may be secondary to other processes related to schizophrenia risk. © Cambridge University Press 2013.

DOI 10.1017/S0033291713000196
Citations Scopus - 16Web of Science - 13
Co-authors Ulrich Schall, Frans Henskens, Pat Michie, Rodney Scott
2013 McCabe KL, Melville JL, Rich D, Strutt PA, Cooper G, Loughland CM, et al., 'Divergent Patterns of Social Cognition Performance in Autism and 22q11.2 Deletion Syndrome (22q11DS)', JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS, 43 1926-1934 (2013) [C1]
DOI 10.1007/s10803-012-1742-2
Citations Scopus - 6Web of Science - 6
Co-authors Ulrich Schall, Linda E Campbell
2013 Schork AJ, Thompson WK, Pham P, Torkamani A, Roddey JC, Sullivan PF, et al., 'All SNPs Are Not Created Equal: Genome-Wide Association Studies Reveal a Consistent Pattern of Enrichment among Functionally Annotated SNPs', PLOS GENETICS, 9 (2013) [C1]
DOI 10.1371/journal.pgen.1003449
Citations Scopus - 63Web of Science - 47
Co-authors Ulrich Schall, Pat Michie, Frans Henskens, Rodney Scott
2012 McCabe KL, Maloney EA, Stain HJ, Loughland CM, Carr VJ, 'Relationship between childhood adversity and clinical and cognitive features in schizophrenia', Journal of Psychiatric Research, 46 600-607 (2012) [C1]
Citations Scopus - 11Web of Science - 12
Co-authors Helen Stain
2011 De Ville M, Baker AL, Lewin TJ, Bucci S, Loughland CM, 'Associations between substance use, neuropsychological functioning and treatment response in psychosis', Psychiatry Research, 186 190-196 (2011) [C1]
DOI 10.1016/j.psychres.2010.08.025
Citations Scopus - 2Web of Science - 1
Co-authors Amanda Baker, Terry Lewin
2011 McCabe KL, Rich D, Loughland CM, Schall UA, Campbell LE, 'Visual scanpath abnormalities in 22q11.2 deletion syndrome: Is this a face specific deficit?', Psychiatry Research, 189 292-298 (2011) [C1]
Citations Scopus - 10Web of Science - 8
Co-authors Linda E Campbell, Ulrich Schall
2011 Gwas Consortium, Henskens FA, Loughland CM, Michie PT, Schall UA, Scott R, 'Genome-wide association study identifies five new schizophrenia loci', Nature Genetics, 43 969-U77 (2011) [C1]
Citations Scopus - 794Web of Science - 413
Co-authors Frans Henskens, Pat Michie, Ulrich Schall, Rodney Scott
2010 Loughland CM, Draganic D, McCabe KL, Richards JM, Nasir MA, Allen J, et al., 'Australian Schizophrenia Research Bank: A database of comprehensive clinical, endophenotypic and genetic data for aetiological studies of schizophrenia', Australian and New Zealand Journal of Psychiatry, 44 1029-1035 (2010) [C1]
DOI 10.3109/00048674.2010.501758
Citations Web of Science - 20
Co-authors Rodney Scott, Frans Henskens, Paul Tooney, Pat Michie, Ulrich Schall
2010 Campbell LE, McCabe KL, Leadbeater KE, Schall UA, Loughland CM, Rich D, 'Visual scanning of faces in 22q11.2 deletion syndrome: Attention to the mouth or the eyes?', Psychiatry Research, 177 211-215 (2010) [C1]
DOI 10.1016/j.psychres.2009.06.007
Citations Scopus - 18Web of Science - 15
Co-authors Linda E Campbell, Ulrich Schall
2010 Loughland CM, Allen J, Gianacas L, Schofield PW, Lewin TJ, Hunter M, Carr VJ, 'Brief neuropsychological profiles in psychosis: A pilot study using the Audio Recorded Cognitive Screen (ARCS)', Acta Neuropsychiatrica, 22 243-252 (2010) [C1]
DOI 10.1111/j.1601-5215.2010.00492.x
Citations Scopus - 5Web of Science - 4
Co-authors Peter Schofield, Mick Hunter, Terry Lewin
2009 Loughland CM, Lawrence G, Allen J, Hunter M, Lewin TJ, Oud NE, Carr VJ, 'Aggression and trauma experiences among carer-relatives of people with psychosis', Social Psychiatry and Psychiatric Epidemiology, 44 1031-1040 (2009) [C1]
DOI 10.1007/s00127-009-0025-5
Citations Scopus - 11Web of Science - 9
Co-authors Mick Hunter, Terry Lewin
2009 Morris RW, Weickert CS, Loughland CM, 'Emotional face processing in schizophrenia', Current Opinion in Psychiatry, 22 140-146 (2009) [C1]
DOI 10.1097/yco.0b013e328324f895
Citations Scopus - 72Web of Science - 61
2007 Loughland CM, Lewin TJ, Carr VJ, Sheedy J, Harris AW, 'RBANS neuropsychological profiles within schizophrenia samples recruited from non-clinical settings', Schizophrenia Research, 89 232-242 (2007) [C1]
DOI 10.1016/j.schres.2006.08.022
Citations Scopus - 24Web of Science - 23
Co-authors Terry Lewin
2004 Loughland CM, Carr VJ, Lewin TJ, Barnard RE, Chapman JL, Walton JM, 'Potential sampling and recruitment source impacts in schizophrenia research', Psychiatry Research: an international journal for rapid communication, 125 117-127 (2004) [C1]
DOI 10.1016/j.psychres.2003.11.002
Citations Scopus - 16Web of Science - 15
Co-authors Terry Lewin
2004 Loughland CM, Williams LM, Harris A, 'Visual scanpath dysfunction in first-degree relatives of schizophrenia probands: evidence for a vunerability marker?', Schizophrenia Research, 67 11-21 (2004) [C1]
DOI 10.1016/S0920-9964(03)00094-X
Citations Scopus - 56Web of Science - 54
2003 Williams LM, Loughland CM, Green MJ, Harris AWF, Gordon E, 'Emotion perception in schizophrenia: An eye movement study comparing the effectiveness of risperidone vs. haloperidol', Psychiatry Research, 120 13-27 (2003) [C1]
DOI 10.1016/s0165-1781(03)00166-5
Citations Scopus - 50Web of Science - 40
2003 Lee KH, Harris AW, Loughland CM, Williams LM, 'The five symptom dimensions and depression in schizophrenia', PSYCHOPATHOLOGY, 36 226-233 (2003)
DOI 10.1159/000073447
Citations Scopus - 28Web of Science - 26
2002 Loughland CM, Williams L, Gordon E, 'Visual scanpaths to positive and negative facial emotions in an outpatient schizophrenia sample', Schizophrenia Research, 55 159-170 (2002) [C1]
Citations Scopus - 121Web of Science - 102
2002 Loughland CM, Williams L, Gordon E, 'Schizophrenia and Affective Disorder Show Different Visual Scanning Behaviour for Faces: A Trait versus State-Based Distinction?', Biological Psychiatry, 52 338-348 (2002) [C1]
Citations Scopus - 89Web of Science - 74
2001 Loughland CM, Carr VJ, Lewin T, 'The NISAD Schizophrenia Research Register: why do we need a database of schizophrenia volunteers?', Australian and New Zealand Journal of Psychiatry, 35 660-667 (2001) [C1]
Citations Scopus - 25Web of Science - 23
Co-authors Terry Lewin
2001 Lee KH, Williams LM, Loughland CM, Davidson DJ, Gordon E, 'Syndromes of schizophrenia and smooth-pursuit eye movement dysfunction', PSYCHIATRY RESEARCH, 101 11-21 (2001)
DOI 10.1016/S0165-1781(00)00242-0
Citations Scopus - 25Web of Science - 21
2001 Williams LM, Senior C, David AS, Loughland CM, Gordon E, 'In search of the "Duchenne smile": Evidence from eye movements', JOURNAL OF PSYCHOPHYSIOLOGY, 15 122-127 (2001)
DOI 10.1027//0269-8803.15.2.122
Citations Scopus - 24Web of Science - 21
2001 Carr VJ, Lewin TJ, Loughland CM, Barnard RE, Johnston PJ, Chapman JL, Walton JM, 'Does the source of sampling make a difference in schizophrenia research?', SCHIZOPHRENIA RESEARCH, 49 258-258 (2001)
Co-authors Terry Lewin
1999 Williams LM, Loughland CM, Gordon E, 'Visual scanpaths and recognition of positive and negative facial emotions in schizophrenia', SCHIZOPHRENIA RESEARCH, 36 268-268 (1999)
Citations Web of Science - 2
1999 Williams LM, Loughland CM, Gordon E, Davidson D, 'Visual scanpaths in schizophrenia: is there a deficit in face recognition?', SCHIZOPHRENIA RESEARCH, 40 189-199 (1999)
DOI 10.1016/S0920-9964(99)00056-0
Citations Scopus - 98Web of Science - 85
1996 Loughland C, Williams L, 'A cluster analytic study of schizotypal trait dimensions', Personality and Individual Differences, 23 877-883 (1996) [C1]
Citations Scopus - 19Web of Science - 15
Show 43 more journal articles

Conference (47 outputs)

Year Citation Altmetrics Link
2013 Phare D, Gu N, Williams T, Loughland C, 'A Semiotic Framework to Understand How Signs in a Collective Design Task Convey Information: A Pilot Study of Design in an Open Crowd Context', Cutting Edge: 47th International Conference of the Architectural Science Association (2013) [E1]
Co-authors Ning Gu
2013 Loughland C, Outram S, Kelly B, Cohen M, 'COMMUNICATING A DIAGNOSIS OF SCHIZOPHRENIA', AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY (2013) [E3]
Co-authors Sue Outram, Brian Kelly
2013 Loughland CM, Kelly B, Outram S, Harris G, Cohan M, Sandhu H, et al., 'Patients' experiences and perceptions of a diagnosis of schizophrenia', AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY (2013) [E3]
Co-authors Brian Kelly, Sue Outram
2013 Outram S, Kelly B, Loughland CM, Harris G, Cohan M, Sandhu H, et al., 'Communicating a diagnosis of schizophrenia: Experiences and perceptions of carers', AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY (2013) [E3]
Co-authors Brian Kelly, Sue Outram
2013 Kelly B, Outram S, Loughland CM, Harris G, Kelly F, Cohan M, et al., 'Communicating a diagnosis of schizophrenia: Experiences and perceptions of mental health clinicians', AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY (2013) [E3]
Co-authors Sue Outram, Brian Kelly
2013 Cohan M, Sandhu H, Vamos M, Ditton-Phare P, Kelly F, Kelly B, et al., 'Communication skills training in psychiatry: An Australia experience', AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY (2013) [E3]
Co-authors Sue Outram, Brian Kelly
2012 Paul DJ, Henskens FA, Loughland CM, McCabe KL, Bridge JE, Duffy L, et al., 'Issues preventing the migration of the Australian Schizophrenia Research Bank to the cloud', Proceedings of the IADIS International Conference On Internet Technologies & Society (2012) [E1]
Co-authors Frans Henskens, Ulrich Schall, Pat Michie, Rodney Scott
2012 Paul DJ, Henskens FA, Loughland CM, Bridge JE, McCabe KL, Carr VJ, et al., 'IT development and management of a live e-research system: Experiences with the Australian Schizophrenia Research Bank', HEALTHINF 2012 - Proceedings of the International Conference on Health Informatics (2012) [E1]
Co-authors Ulrich Schall, Pat Michie, Frans Henskens, Rodney Scott
2012 Loughland CM, McCabe KL, Bridge JE, Henskens FA, Catts S, Jablensky A, et al., 'The Australian Schizophrenia Research Biobank (ASRB): An audit of the first five years of recruitment resource access', Schizophrenia Research (2012) [E3]
Co-authors Frans Henskens, Paul Tooney, Pat Michie, Ulrich Schall, Rodney Scott
2012 Henskens FA, Paul DJ, Loughland CM, Bridge JE, McCabe KL, Catts S, et al., 'The Australian Schizophrenia Research Biobank (ASRB): IT development and management of a live e-research system', Schizophrenia Research (2012) [E3]
Co-authors Frans Henskens, Paul Tooney, Pat Michie, Ulrich Schall
2011 McCabe K, McCabe K, Loughland CM, Hunter M, Lewin T, Carr VJ, 'A BOTTOM-UP BIOFEEDBACK REMEDIATION IMPROVES EMOTION RECOGNITION IN SCHIZOPHRENIA: EVIDENCE FROM A VISUAL SCAN PATH PILOT STUDY', SCHIZOPHRENIA BULLETIN (2011) [E3]
Co-authors Terry Lewin, Mick Hunter
2011 Maloney E, McCabe KL, Bridge J, Stain HJ, Loughland CM, Carr V, 'Childhood adversity in schizophrenia: Neurocognitive and clinical correlates from the Australian schizophrenia research bank (ASRB)', Schizophrenia Bulletin (2011) [E3]
Co-authors Helen Stain
2011 Loughland CM, McCabe KL, Catts S, Jablensky A, Henskens FA, Michie PT, et al., 'The Australian Schizophrenia Research Bank (ASRB): The first 550 schizophrenia sample profile', Schizophrenia Bulletin (2011) [E3]
Co-authors Rodney Scott, Ulrich Schall, Pat Michie, Paul Tooney, Frans Henskens
2010 McCabe KL, Bridge J, Loughland CM, Carr V, 'Childhood adversity in a schizophrenia population: Data from the Australian Schizophrenia Research Bank (ASRB)', Australian & New Zealand Journal of Psychiatry (2010) [E3]
2010 McCabe KL, Loughland CM, Hunter M, Lewin TJ, Carr VJ, 'Remediation of emotion recognition in schizophrenia using biofeedback: Evdience from a visual scan path pilot study', Australian & New Zealand Journal of Psychiatry (2010) [E3]
Co-authors Mick Hunter, Terry Lewin
2010 Paulik G, Atkinson RJ, Carr V, Clark S, Curtis J, Langdon R, et al., 'Minds in transition (MINT): A prospective study examining neurocognitive correlates of transition from ultra-high risk mental state to schizophrenia', Australian & New Zealand Journal of Psychiatry (2010) [E3]
Co-authors Juanita Todd, Ulrich Schall, Pat Michie, Helen Stain, Renate Thienel, Paul Tooney
2010 Carr V, Loughland CM, McCabe KL, Nasir A, Stan C, Jablensky A, et al., 'The Australian Schizophrenia Research Bank (ASRB): Demographic, clinical and neuropsychological profiles for the first 500 participants with schizophrenia', Schizophrenia Research (2010) [E3]
Co-authors Frans Henskens, Rodney Scott, Ulrich Schall, Pat Michie
2010 Henskens FA, Carr VJ, Catts S, Jablensky A, Michie PT, Loughland CM, et al., 'The Australian Schizophrenia Research Bank (ASRB): An example of eresearch', Schizophrenia Research (2010) [E3]
Co-authors Frans Henskens, Ulrich Schall, Pat Michie, Rodney Scott
2010 McCabe KL, Loughland CM, Hunter M, Lewin TJ, Carr VJ, 'A bottom-up biofeedback remediation improves emotion recognition in schizophrenia: Evidence from a visual scan path pilot study', Schizophrenia Research (2010) [E3]
Co-authors Terry Lewin, Mick Hunter
2010 McCabe KL, Loughland CM, Nasir MA, Catts S, Jablensky A, Henskens FA, et al., 'The Australian Schizophrenia Research Bank (ASRB): Quality assurance and control for a comprehensive clinical, neuropsychological, genetic and neuroimaging database for researchers', Schizophrenia Research (2010) [E3]
Co-authors Ulrich Schall, Pat Michie, Frans Henskens, Rodney Scott
2010 Ayre M, Loughland CM, Bore MR, Baker AL, 'The relationship between social problem-solving and emotional regulation in people with schizophrenia', Schizophrenia Research (2010) [E3]
Co-authors Amanda Baker, Miles Bore
2009 Henskens FA, Carr VJ, Catts SV, Jablenski A, Michie PT, Loughland CM, et al., 'An Example of eResearch: The Australian Schizophrenia Research Bank', Proceedings eResearch 2009 (2009)
Co-authors Ulrich Schall, Pat Michie, Frans Henskens, Rodney Scott
2009 Henskens FA, Loughland CM, Aphale MS, Paul D, Richards JM, Rasser P, et al., 'it support for the australian schizophrenia research bank', HEALTHINF 2009 - Proceedings of the 2nd International Conference on Health Informatics (2009) [E1]
Co-authors Pat Michie, Ulrich Schall, Frans Henskens, Rodney Scott
2009 Carr VJ, Loughland CM, Catts S, Henskens FA, Jablensky A, Michie PT, et al., 'A database of comprehensive clinical, endophenotypic and genetic data for aetiological studies of schizophrenia', Schizophrenia Bulletin (2009) [E3]
DOI 10.1093/schbul/sbn173
Co-authors Ulrich Schall, Pat Michie, Frans Henskens, Rodney Scott
2009 Loughland CM, Richards J, Aphale M, Henskens FA, Carr VJ, Catts SV, et al., 'The Australian Schizophrenia Research Bank (ASRB): The development of an electronically delivered clinical assessment battery', Schizophrenia Bulletin (2009) [E3]
DOI 10.3109/00048674.2010.501758
Citations Scopus - 31
Co-authors Frans Henskens, Pat Michie, Ulrich Schall, Terry Lewin, Rodney Scott
2008 Carr VJ, Loughland CM, Catts SV, Henskens FA, Jablensky A, Michie PT, et al., 'A progress report on the Australian Schizophrenia Research Bank', Australian and New Zealand Journal of Psychiatry (2008) [E3]
Co-authors Rodney Scott, Pat Michie, Frans Henskens, Ulrich Schall
2008 Campbell LE, McCabe KL, Leadbeater KE, Rich D, Schall UA, Loughland CM, 'Visual scan paths in young adults with velo-cardio-facial syndrome (22Q11.2 Deletion Syndrome)', Australian and New Zealand Journal of Psychiatry (2008) [E3]
Co-authors Linda E Campbell, Ulrich Schall
2008 Richards J, Loughland CM, Aphale M, Henskens FA, Carr VJ, Catts SV, et al., 'The Australian Schizophrenia Research Bank (ASRB) computer-based clinical assessment software (CAS): Development and application', Australian and New Zealand Journal of Psychiatry (2008) [E3]
Co-authors Frans Henskens, Pat Michie, Ulrich Schall, Terry Lewin, Rodney Scott
2008 Thornton LK, Baker AL, Johnson MP, Loughland CM, Lewin TJ, Kay-Lambkin FJ, 'An exploration of drug attitudes and knowledge among people with psychotic disorders', Australian and New Zealand Journal of Psychiatry (2008) [E3]
Co-authors Terry Lewin, Amanda Baker, Martin Johnson
2008 Loughland CM, McCabe KL, Johnston PJ, Lewin TJ, Carr VJ, 'Performance on the tile matrix task provides further evidence of visuo-cognitive disturbances in the first-degree relatives of schizophrenia patients', Australian and New Zealand Journal of Psychiatry (2008) [E3]
Co-authors Terry Lewin
2008 McCabe KL, Loughland CM, Hunter M, Lewin TJ, Carr VJ, 'Randomised control trial of emotion perception remediation among people with schizophrenia', Australian and New Zealand Journal of Psychiatry (2008) [E3]
Co-authors Terry Lewin, Mick Hunter
2008 Sly K, Loughland CM, Lewin TJ, Hunter M, 'Facial expression processing in schizophrenia: Associations with psychopathy, syptomatology and emotion recognition', Australian and New Zealand Journal of Psychiatry (2008) [E3]
Co-authors Mick Hunter, Terry Lewin
2008 Campbell LE, McCabe KL, Cruickshank L, Leadbeater KE, Schall UA, Karayanidis F, Loughland CM, 'Social cognitive skills and visual scan paths in children and young adults with velo-cardio-facial syndrom (22Q11.2 Deletion Syndrome)', Australian and New Zealand Journal of Psychiatry (2008) [E3]
DOI 10.1080/00048670802441844
Co-authors Ulrich Schall, Frini Karayanidis, Linda E Campbell
2007 McCabe KL, Loughland CM, Cohen M, Hunter M, Lewin TJ, Carr VJ, 'Remediation of facial affect decoding and visual scanpath deficits in schizophrenia', Schizophrenia Bulletin (2007) [E3]
Citations Web of Science - 1
Co-authors Mick Hunter, Terry Lewin
2007 Loughland CM, McCabe KL, Hunter M, Lewin TJ, Carr VJ, 'Are facial information retention/integration deficits in first-degree relatives of schizophrenia patients further evidence of a vulnerability marker?', Schizophrenia Bulletin (2007) [E3]
Co-authors Mick Hunter, Terry Lewin
2007 Lewin TJ, Loughland CM, Carr VJ, Baker A, 'A recruitment source impacts in schizophrenia research', Schizophrenia Bulletin (2007) [E3]
Co-authors Terry Lewin, Amanda Baker
2007 Carr VJ, Loughland CM, Draganic B, Lewin TJ, Schall UA, Scott R, et al., 'The Australian Schizophrenia Research Bank (ASRB)', Schizophrenia Bulletin (Abstracts of the 11th International Congress on Schizophrenia Research) (2007) [E3]
Co-authors Terry Lewin, Frans Henskens, Ulrich Schall, Rodney Scott, Pat Michie
2007 Loughland CM, Carr VJ, Michie PT, Stain HJ, Badcock J, Jablenski A, et al., 'The national recruitment and assessment of people with schizophrenia: The ASRB experience', Australian and New Zealand Journal of Psychiatry (2007) [E3]
Co-authors Ulrich Schall, Pat Michie, Helen Stain
2007 Loughland C, Michie PM, Stain H, Babcock J, Jablensky A, Draganic D, et al., 'The national recruitment and assessment of people with schizophrenia: The ASRB experience', Proceedings ASPR 2007 (2007)
Co-authors Frans Henskens, Pat Michie, Rodney Scott, Terry Lewin, Ulrich Schall
2006 Loughland CM, McCabe KL, Johnston PJ, Lewin TJ, Carr VJ, 'Are visuo-cognitive disturbances in first degree relatives of schizophrenia patients evidence for a vulnerability marker? (Poster presentation)', Abstracts from the XIIIth Biennial Winter Workshop on Schizophrenia Research (Schizophrenia Research (Vol 81, Sup 1)) (2006) [E3]
Co-authors Terry Lewin
2006 Loughland CM, McCabe KL, Johnston PJ, Lewin (Ext) T, Carr VJ, 'Are visuo-cognitive disturbances infirst degree relatives of schizophrenia patients evidence for a vulnerabliity marker', Australan & New Zealand Journal of Psychiatry (2006) [E3]
Co-authors Terry Lewin
2006 McCabe KL, Loughland CM, Cohen M, Johnston PJ, Hunter M, Lewin TJ, Carr VJ, 'Remediation of facial affect decoding and visual scanpath deficits in schizophrenia', Australian and New Zealand Journal of Psychiatry (2006) [E3]
Co-authors Mick Hunter, Terry Lewin
2005 Lawrence G, Loughland CM, Lewin (Ext) T, Carr VJ, 'NISAD Schizophrenia research register: characterizing the first-degree relative volunteers', Abstracts for The Royal Australian & NZ College of Psychiatrists Joint CINP/ASPR Scientific Meeting (2005) [E3]
2005 Russell SH, Loughland CM, Tooney PA, Scott R, Carr VJ, 'The Hunter DNA bank for schizophrenia and allied disorders: A unique Australian Resource facilitating genetic research into mental illness', Abstracts for The Royal Australian & NZ College of Psychiatrists Joint CINP/ASPR Scientific Meeting (2005) [E3]
Co-authors Rodney Scott, Paul Tooney
2005 Loughland CM, McCabe KL, Johnston PJ, Lewin (Ext) T, Carr VJ, 'Visuo-cognitive deficits in schizophrenia and first-degree relatives', Abstracts of The Royal Australian & NZ College of Psychiatrists Joint CINP/ASPR Scientific Meeting (2005) [E3]
2005 Loughland CM, Lewin TJ, Carr VJ, Harris AW, 'RBANS neuropsychological profiles within schizophrenia samples recruited from non-treatment settings', SCHIZOPHRENIA BULLETIN (2005)
Co-authors Terry Lewin
2003 Loughland CM, Williams LM, Gordon E, 'Schizophrenia and affective disorder show different visual scanpath patterns to faces and facial expressions: Is this a trait versus state-based distinction?', SCHIZOPHRENIA RESEARCH (2003)
DOI 10.1016/S0920-9964(03)80413-9
Show 44 more conferences
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Grants and Funding

Summary

Number of grants 18
Total funding $1,390,077

Click on a grant title below to expand the full details for that specific grant.


20151 grants / $392,162

Associate Professor of Translational Research in Mental Health $392,162

Funding body: Hunter New England Local Health District

Funding body Hunter New England Local Health District
Project Team Doctor Carmel Loughland, Conjoint Associate Professor Martin Cohen
Scheme Research Funds
Role Lead
Funding Start 2015
Funding Finish 2017
GNo G1500836
Type Of Funding Other Public Sector - State
Category 2OPS
UON Y

20141 grants / $2,000

Joint Ottawa CCME Conference 2014, Ottawa Canada, 25-29 April 2014$2,000

Funding body: University of Newcastle - Faculty of Health and Medicine

Funding body University of Newcastle - Faculty of Health and Medicine
Project Team Doctor Carmel Loughland
Scheme Travel Grant
Role Lead
Funding Start 2014
Funding Finish 2014
GNo G1400493
Type Of Funding Internal
Category INTE
UON Y

20131 grants / $2,000

International Congress on Schizophrenia Research (ICOSR), JW Marriott Hotel, Orlando Great Lakes, Florida USA, 21 - 25 April 2013$2,000

Funding body: University of Newcastle - Faculty of Health and Medicine

Funding body University of Newcastle - Faculty of Health and Medicine
Project Team Doctor Carmel Loughland
Scheme Travel Grant
Role Lead
Funding Start 2013
Funding Finish 2013
GNo G1300180
Type Of Funding Internal
Category INTE
UON Y

20124 grants / $112,000

Technical officer to support the Australian Schizophrenia Research Bank (ASRB)$70,000

Funding body: Schizophrenia Research Institute

Funding body Schizophrenia Research Institute
Project Team Professor Rodney Scott, Doctor Carmel Loughland
Scheme Research Grant
Role Investigator
Funding Start 2012
Funding Finish 2013
GNo G1200834
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Testing for N-methyl-D-aspartate (NMDA) receptor antibodies in a large Australian cohort of schizophrenia patients$30,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Associate Professor Paul Tooney, Mr Paul Rasser, Mr TIM Ehlkes, Emeritus Professor Patricia Michie, Professor Ulli Schall, Doctor Carmel Loughland
Scheme Project Grant
Role Investigator
Funding Start 2012
Funding Finish 2012
GNo G1200854
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Testing for N-methyl-D-aspartate (NMDA) receptor antibodies in a large Australian cohort of schizophrenia patients$10,000

Funding body: Schizophrenia Research Institute

Funding body Schizophrenia Research Institute
Project Team Associate Professor Paul Tooney, Associate Professor Ute Vollmer-Conna, Mr Paul Rasser, Mr TIM Ehlkes, Emeritus Professor Patricia Michie, Professor Ulli Schall, Doctor Carmel Loughland
Scheme Research Grant
Role Investigator
Funding Start 2012
Funding Finish 2012
GNo G1201020
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

3rd Biennial Schizophrenia International Research Society (SIRS), Fortezza de Basso, Florence Italy, 13 - 18 April 2012$2,000

Funding body: University of Newcastle - Faculty of Health and Medicine

Funding body University of Newcastle - Faculty of Health and Medicine
Project Team Doctor Carmel Loughland
Scheme Travel Grant
Role Lead
Funding Start 2012
Funding Finish 2012
GNo G1200500
Type Of Funding Internal
Category INTE
UON Y

20111 grants / $51,930

Here's looking at you, kid: Face processing, emotional availability and reflective functioning in mothers with postnatal depression$51,930

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Carmel Loughland, Doctor Linda Campbell
Scheme Project Grant
Role Lead
Funding Start 2011
Funding Finish 2012
GNo G1001024
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

20073 grants / $594,985

Technical Officer to Support the Australian Schizophrenia Research Bank (ASRB)$438,985

Funding body: Schizophrenia Research Institute

Funding body Schizophrenia Research Institute
Project Team Associate Professor Frans Henskens, Doctor Carmel Loughland
Scheme Research Grant
Role Investigator
Funding Start 2007
Funding Finish 2013
GNo G0187035
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

HMRI Postdoctoral Fellowship in Youth Mental Health Research$150,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Professor Ulli Schall, Emeritus Professor Patricia Michie, Associate Professor Paul Tooney, Associate Professor Helen Stain, Doctor Carmel Loughland, Conjoint Professor Vaughan Carr
Scheme Postdoctoral Fellowship
Role Investigator
Funding Start 2007
Funding Finish 2009
GNo G0188274
Type Of Funding Donation - Aust Non Government
Category 3AFD
UON Y

Visuo-cognitive deficits in schizophrenia patients and their first degree relatives$6,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Carmel Loughland
Scheme PULSE Early Career Researcher of the Year Award
Role Lead
Funding Start 2007
Funding Finish 2007
GNo G0187400
Type Of Funding Donation - Aust Non Government
Category 3AFD
UON Y

20053 grants / $137,000

Facial expression processing deficits in schizophrenia patients and their biological 1st-degree relatives$70,000

Funding body: Neuroscience Institute of Schizophrenia and Allied Disorders

Funding body Neuroscience Institute of Schizophrenia and Allied Disorders
Project Team Ms Kathryn McCabe, Doctor Carmel Loughland, Conjoint Associate Professor Mick Hunter, Mr Patrick Johnston
Scheme Postgraduate Research Scholarship
Role Lead
Funding Start 2005
Funding Finish 2008
GNo G0185368
Type Of Funding Donation - Aust Non Government
Category 3AFD
UON Y

Schizophrenia DNA Bank.$59,000

Funding body: Australian Rotary Health

Funding body Australian Rotary Health
Project Team

Carr V

Scheme Unknown
Role Investigator
Funding Start 2005
Funding Finish 2007
GNo
Type Of Funding Not Known
Category UNKN
UON N

Remediation of facial affect decoding and visual scanpath deficits in schizophrenia$8,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Doctor Carmel Loughland, Conjoint Associate Professor Martin Cohen, Mr Patrick Johnston, Conjoint Professor Vaughan Carr
Scheme Project Grant
Role Lead
Funding Start 2005
Funding Finish 2005
GNo G0184792
Type Of Funding Internal
Category INTE
UON Y

20042 grants / $85,000

Facial expression processing deficits in schizophrenia and their first degree relatives.$48,000

Funding body: National Alliance for Research on Schizophrenia and Depression

Funding body National Alliance for Research on Schizophrenia and Depression
Project Team

Loughland CM

Scheme Unknown
Role Lead
Funding Start 2004
Funding Finish 2005
GNo
Type Of Funding International - Non Competitive
Category 3IFB
UON N

Technical support for the Hunter DNA Bank for Schizophrenia and Allied Disorders$37,000

Funding body: Hunter Medical Research Institute (HMRI)

Funding body Hunter Medical Research Institute (HMRI)
Project Team

Tooney, P

Scheme Unknown
Role Investigator
Funding Start 2004
Funding Finish 2005
GNo
Type Of Funding External
Category EXTE
UON N

20032 grants / $13,000

Assessment of somatosensory function in subjects with schizophrenia: touch, pain and axon reflex flare.$11,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Conjoint Professor Loris Chahl, Conjoint Professor Vaughan Carr, Associate Professor Paul Tooney, Doctor Carmel Loughland, Professor Mike Calford
Scheme Project Grant
Role Investigator
Funding Start 2003
Funding Finish 2003
GNo G0182466
Type Of Funding Internal
Category INTE
UON Y

Travel Grant to attend International Congress on Schizophrenia Research, Colorado Springs USA$2,000

Funding body: Ian Potter Foundation

Funding body Ian Potter Foundation
Project Team

Loughland, CM

Scheme Travel Grant
Role Lead
Funding Start 2003
Funding Finish 2003
GNo
Type Of Funding External
Category EXTE
UON N
Edit

Research Supervision

Number of supervisions

Completed4
Current5

Total current UON EFTSL

PhD1.65

Current Supervision

Commenced Level of Study Research Title / Program / Supervisor Type
2015 PhD ComPsych: Doctor-patient communication in mental health - Improving the patient experience
PhD (Medicine), Faculty of Health and Medicine, The University of Newcastle
Principal Supervisor
2015 PhD The discursive structuring of antipsychotic medication within clinical decision-making practices and the impact on recovery for people diagnosed with schizophrenia or schizoaffective disorder
PhD (Medicine), Faculty of Health and Medicine, The University of Newcastle
Co-Supervisor
2012 PhD Here's Looking at You, Kid: Face Processing, Emotional Availability and Reflective Functioning in Mothers with Postnatal Depression
PhD (Clinical Psychology), Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2009 PhD Facial Expression Processing in Individuals with Schizophrenia: Associations with Psychopathy, Symptomatology amd Emotion Regulation
PhD (Clinical Psychology), Faculty of Science and Information Technology, The University of Newcastle
Principal Supervisor
2006 Masters Visual scanpath impairement in schizophrenia: The role of psychopathy.
Psychology, University of Newcastle
Principal Supervisor

Past Supervision

Year Level of Study Research Title / Program / Supervisor Type
2012 PhD Face Emotion Processing Deficits in Schizophrenia: Identification and Remediation Utilising Visual Scanpath Technology
PhD (Psychiatry), Faculty of Health and Medicine, The University of Newcastle
Principal Supervisor
2011 PhD Face emotion processing deficits in schizophrenia: Identification and remediation utilising visual scanpath technology
Psychology, University of Newcastle
Principal Supervisor
2007 Masters An examination of the utility of two cognitive screeners, the ARCS (Audio Recorded Cognitive Screen) and RBANS (Repeatable Battery Assessment for Neuropsychological Status) in detecting neuropsychological impairement in schizophrenia.
Psychology, University of Newcastle
Principal Supervisor
2007 Masters Distress and PTSD in the first-degree relatives of schizophrenia patients: What is the impact of exposure to aggression and violence?
Psychology, University of Newcastle
Principal Supervisor
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News

schizophrenia

Landmark schizophrenia genetic study

July 23, 2014

UON researchers have helped unearth more than 100 genetic variants associated with schizophrenia, after contributing to the largest genome-wide study of the disease ever conducted.

Dr Carmel Loughland

Position

Associate Professor
PR Centre for Translational Neuroscience and Mental Health Research
School of Medicine and Public Health
Faculty of Health and Medicine

Focus area

Public Health

Contact Details

Email carmel.loughland@newcastle.edu.au
Phone (02) 4033 5722
Mobile 0413000507
Fax (02) 4033 5692

Office

Room Level 5, Room 5020
Building McAuley Building
Location Mater Hospital

,
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