Associate Professor Alison Lane

Associate Professor Alison Lane

Associate Professor

School of Health Sciences

Career Summary

Biography

Research Expertise
My name is Alison Lane and I study sensory features in Autism Spectrum Disorder at the University of Newcastle, Australia. The focus of my work to date has been to identify sensory subtypes in Autism. My studies show that sensory features in Autism vary on the basis of parent reports of the frequency of the behaviours and the sensory modalities affected. Further, these subtypes relate to distinct neural profiles and patterns of challenging behaviours. My current work seeks to validate the use of sensory features as a method of classifying individuals with Autism into clinically meaningful phenotypes. To this end, I am involved in studies examining neurophysiological variation in sensory subtypes (e.g. using event-related potentials, heart rate and electrodermal responsivity). Future studies will explore differential response to treatment in individuals with Autism Spectrum Disorder based on sensory subtype classification and chart the emergence of sensory subtypes pre-diagnostically in early childhood.

Qualifications

  • Doctor of Philosophy, University of Queensland
  • Bachelor of Occupational Therapy, University of Queensland
  • Bachelor of Occupational Therapy (Honours), University of Queensland

Keywords

  • autism
  • autism spectrum disorder
  • child development
  • children
  • evidence based practice
  • neurodevelopmental disability
  • occupational therapy
  • professional practice
  • research methods
  • sensory
  • sensory subtypes

Fields of Research

Code Description Percentage
110321 Rehabilitation and Therapy (excl. Physiotherapy) 40
170112 Sensory Processes, Perception and Performance 60

Professional Experience

UON Appointment

Title Organisation / Department
Associate Professor University of Newcastle
School of Health Sciences
Australia
Edit

Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Journal article (25 outputs)

Year Citation Altmetrics Link
2014 Schaaf RC, Lane AE, 'Toward a Best-Practice Protocol for Assessment of Sensory Features in ASD', Journal of Autism and Developmental Disorders, (2014)

Sensory difficulties are a commonly occurring feature of autism spectrum disorders and are now included as one manifestation of the ¿restricted, repetitive patterns of behavior, ... [more]

Sensory difficulties are a commonly occurring feature of autism spectrum disorders and are now included as one manifestation of the ¿restricted, repetitive patterns of behavior, interests, or activities¿ diagnostic criteria of the DSM5 necessitating guidelines for comprehensive assessment of these features. To facilitate the development of such guidelines, this paper provides an overview of the literature on sensory features in autism spectrum disorder. We summarize the literature pertaining to: terminology, current assessment practices, sensory development, and the relationship of sensory features to core symptoms of autism. The paper concludes with recommendations for clinical assessment of sensory features in Autism.

DOI 10.1007/s10803-014-2299-z
2014 Lane AE, Heathcock JC, 'Early sensory-motor signs of Autism Spectrum Disorder: Implications for clinical practice', Developmental Disabilities Special Interest Section Quarterly, 37 1-3 (2014) [C3]
2014 Eldridge J, Lane AE, Belkin M, Dennis S, 'Robust features for the automatic identification of autism spectrum disorder in children.', J Neurodev Disord, 6 12 (2014) [C1]
DOI 10.1186/1866-1955-6-12
Citations Web of Science - 2
Co-authors Simon Dennis
2014 Lane AE, Molloy CA, Bishop SL, 'Classification of children with autism spectrum disorder by sensory subtype: A case for sensory-based phenotypes', Autism Research, 7 322-333 (2014) [C1]

This study examines whether sensory differences can be used to classify meaningful subgroups of children with autism spectrum disorder (ASD). Caregivers of children with ASD aged ... [more]

This study examines whether sensory differences can be used to classify meaningful subgroups of children with autism spectrum disorder (ASD). Caregivers of children with ASD aged 2-10 years (n=228) completed the Short Sensory Profile. Model-based cluster analysis was used to extract sensory subtypes. The relationship of these subtypes to age, gender, autism symptom severity, and nonverbal intelligence quotient (IQ) was further explored. Four distinct sensory subtypes were identified: (a) sensory adaptive; (b) taste smell sensitive; (c) postural inattentive; and (d) generalized sensory difference. The sensory subtypes differ from each other on two dimensions: (a) the severity of reported sensory differences; and (b) the focus of differences across auditory, taste, smell, vestibular and proprioceptive domains. Examination of the clinical features of each subtype reveals two possible mechanisms of sensory disturbance in autism: (a) sensory hyperreactivity; and (b) difficulties with multisensory processing. Further, the sensory subtypes are not well explained by other variables such as age, gender, IQ, and autism symptom severity. We conclude that classification of children using sensory differences offers a promising method by which to identify phenotypes in ASD. Sensory-based phenotypes may be useful in identifying behavioral features responsive to specific interventions thereby improving intervention effectiveness. Further validation of the sensory-based phenotypes by establishing neural and physiological correlates is recommended. Autism Res 2014, 7: 322-333. © 2014 International Society for Autism Research, Wiley Periodicals, Inc.

DOI 10.1002/aur.1368
Citations Scopus - 3Web of Science - 3
2014 Lane AE, Geraghty ME, Young GS, Rostorfer JL, 'Problem eating behaviors in autism spectrum disorder are associated with suboptimal daily nutrient intake and taste/smell sensitivity', Infant, Child, and Adolescent Nutrition, 6 172-180 (2014) [C1]

Thirty children with autism spectrum disorder (ASD) aged 3 to 10 years participated in this study exploring associations between problem eating behaviors, daily nutrient intake, a... [more]

Thirty children with autism spectrum disorder (ASD) aged 3 to 10 years participated in this study exploring associations between problem eating behaviors, daily nutrient intake, and sensory disturbance. Parents completed surveys regarding the usual eating behaviors of their children. Children exhibiting more severe autism-specific disruptive behaviors at mealtimes were most at risk for suboptimal intake of select nutrients such as biotin, vitamin K, iodine, linolenic omega-3 fatty acids, and choline, which play a role in metabolism and bone and brain health. Children exhibiting food refusal tended to have increased caloric and nutrient intake. Picky eaters were more likely to consume adequate daily nutrients but experienced the highest levels of parent-reported taste/smell sensitivity. The findings of this preliminary study support a multifactorial approach to the management of problem eating behaviors in ASD. © 2014 The Author(s).

DOI 10.1177/1941406414523981
2013 Phillips RL, Olds T, Boshoff K, Lane AE, 'Measuring activity and participation in children and adolescents with disabilities: A literature review of available instruments', AUSTRALIAN OCCUPATIONAL THERAPY JOURNAL, 60 288-300 (2013) [D1]
DOI 10.1111/1440-1630.12055
Citations Scopus - 2Web of Science - 2
2013 Egelhoff K, Lane AE, 'Brief Report: Preliminary Reliability, Construct Validity and Standardization of the Auditory Behavior Questionnaire (ABQ) for Children with Autism Spectrum Disorders', JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS, 43 978-984 (2013) [C1]
DOI 10.1007/s10803-012-1626-5
Citations Scopus - 1
2012 Case-Smith J, Holland T, Lane A, White S, 'Effect of a Coteaching Handwriting Program for First Graders: One-Group Pretest-Posttest Design', AMERICAN JOURNAL OF OCCUPATIONAL THERAPY, 66 396-405 (2012) [C1]
DOI 10.5014/ajot.2012.004333
Citations Scopus - 8Web of Science - 5
2012 Lane A, Harpster K, Heathcock J, 'Motor Characteristics of Young Children Referred for Possible Autism Spectrum Disorder', PEDIATRIC PHYSICAL THERAPY, 24 21-29 (2012) [C1]
DOI 10.1097/PEP.0b013e31823e071a
Citations Scopus - 7Web of Science - 5
2011 Raghavendra P, Virgo R, Olsson C, Connell T, Lane AE, 'Activity participation of children with complex communication needs, physical disabilities and typically-developing peers', DEVELOPMENTAL NEUROREHABILITATION, 14 145-155 (2011) [C1]
DOI 10.3109/17518423.2011.568994
Citations Scopus - 21Web of Science - 20
2011 Lane AE, Dennis SJ, Geraghty ME, 'Brief Report: Further Evidence of Sensory Subtypes in Autism', JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS, 41 826-831 (2011) [C1]
DOI 10.1007/s10803-010-1103-y
Citations Scopus - 24Web of Science - 18
Co-authors Simon Dennis
2010 Geraghty ME, Depasquale GM, Lane AE, 'Nutritional Intake and Therapies in Autism: A Spectrum of What We Know: Part 1', ICAN: Infant, Child, & Adolescent Nutrition, 2 62-69 (2010) [C1]
DOI 10.1177/1941406409358437
2010 Geraghty ME, Bates-Wall J, Ratliff-Schaub K, Lane AE, 'Nutritional Interventions and Therapies in Autism: A Spectrum of What We Know: Part 2', ICAN: Infant, Child, & Adolescent Nutrition, 2 120-133 (2010) [C1]
DOI 10.1177/1941406410366848
2010 Maher CA, Williams MT, Olds T, Lane AE, 'An internet-based physical activity intervention for adolescents with cerebral palsy: a randomized controlled trial', DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY, 52 448-455 (2010) [C1]
DOI 10.1111/j.1469-8749.2009.03609.x
Citations Scopus - 16Web of Science - 14
2010 Lane AE, Young RL, Baker AEZ, Angley MT, 'Sensory Processing Subtypes in Autism: Association with Adaptive Behavior', JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS, 40 112-122 (2010) [C1]
DOI 10.1007/s10803-009-0840-2
Citations Scopus - 76Web of Science - 74
2010 Taylor RL, Olds T, Boshoff K, Lane AE, 'Children's conceptualization of the term 'satisfaction': relevance for measuring health outcomes', CHILD CARE HEALTH AND DEVELOPMENT, 36 663-669 (2010) [C1]
DOI 10.1111/j.1365-2214.2010.01105.x
Citations Scopus - 1Web of Science - 1
2010 Gibbs D, Boshoff K, Lane A, 'Understanding parenting occupations in neonatal intensive care: application of the Person-Environment-Occupation Model', BRITISH JOURNAL OF OCCUPATIONAL THERAPY, 73 55-63 (2010) [C3]
DOI 10.4276/030802210X12658062793762
Citations Scopus - 2Web of Science - 1
2010 Lane AE, Ziviani JM, 'Factors influencing skilled use of the computer mouse by school-aged children', COMPUTERS & EDUCATION, 55 1112-1122 (2010) [C1]
DOI 10.1016/j.compedu.2010.05.008
Citations Scopus - 10Web of Science - 6
2008 Baker AEZ, Lane A, Angley MT, Young RL, 'The relationship between sensory processing patterns and behavioural responsiveness in autistic disorder: A pilot study', JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS, 38 867-875 (2008) [C1]
DOI 10.1007/s10803-007-0459-0
Citations Scopus - 71Web of Science - 57
2008 Maher CA, Olds T, Williams MT, Lane AE, 'Self-reported quality of life in adolescents with cerebral palsy', Physical and Occupational Therapy in Pediatrics, 28 41-57 (2008) [C1]

Health Related Quality of Life (HRQOL) is an important outcome in the delivery of health care. Research on the HRQOL in young people with cerebral palsy (CP) has relied on proxy-r... [more]

Health Related Quality of Life (HRQOL) is an important outcome in the delivery of health care. Research on the HRQOL in young people with cerebral palsy (CP) has relied on proxy-reports from parents. The purpose of this study was to investigate the self-reported HRQOL of young people with CP. A survey was mailed to 229 adolescents with CP in South Australia, of which 118 responded (51.5%). Seventy-one participants 11 to 17 years of age, self-reported HRQOL on the Pediatric Quality of Life Inventory 4.0 (PedsQL). Thirty-eight youth were deemed by their parent/guardian as having insufficient cognitive ability to self-report HRQOL and nine respondents returned their surveys incomplete. The mean PedsQL Physical Function score was 57.3 (SD = 24.3), the mean Psychosocial Function score was 64.5 (SD = 15.9), and the Overall PedsQL score was 62.0 (SD = 16.7). Compared to norms for children without disabilities, 67% of participants had an Overall PedsQL score greater than 1 SD below the mean. PedsQL scores were related to gross motor function classification level (Spearman's rho = -0.54), number of health issues (rho = -0.51), and socioeconomic status (rho = 0.28), but not age, gender, quality of sleep, or whether parent assistance was needed to complete the PedsQL. The results have implications for policy and efforts to identify and address barriers to full and satisfying participation in mainstream schools and community activities.

DOI 10.1300/J006v28n01_04
Citations Scopus - 16
2007 Maher CA, Williams MT, Olds T, Lane AE, 'Physical and sedentary activity in adolescents with cerebral palsy', DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY, 49 450-457 (2007)
Citations Scopus - 105Web of Science - 102
2003 Lane A, Ziviani J, 'Assessing childrens competence in computer interactions: Preliminary reliability and validity of the test of mouse proficiency', OTJR-OCCUPATION PARTICIPATION AND HEALTH, 23 18-26 (2003)
Citations Web of Science - 5
2002 Lane A, Ziviani J, 'Enabling computer access: Introduction to the test of mouse proficiency', OTJR-OCCUPATION PARTICIPATION AND HEALTH, 22 111-118 (2002)
Citations Web of Science - 6
1999 Lane A, Ziviani J, 'Children's computer access: Analysis of the visual-motor demands of software designed for children', British Journal of Occupational Therapy, 62 19-25 (1999)

As technology access becomes an increasingly important activity of daily living, debate persists as to the manner in which computers are best able to assist children in educationa... [more]

As technology access becomes an increasingly important activity of daily living, debate persists as to the manner in which computers are best able to assist children in educational and recreational settings. In particular, information regarding the suitability of commonly used child-computer interfaces is required. Occupational therapists are uniquely qualified to assess and problem-solve computer access issues but, to date, have limited the application of this skill to the areas of rehabilitation and disability. This paper describes a process where the traditional occupational therapy tool of task analysis was used to identify the visual-motor demands of the children's computer game packages that use the mouse for operation. The first author examined 12 game packages comprising 45 separate games and applications and recorded information on the types of movement, task design features and recommended ages for all games. The results of the analysis are discussed in terms of the degree of visual-motor development that is required of children accessing these games and the implications for game designers producing developmentally sensitive software.

Citations Scopus - 4
1997 Lane AE, Ziviani JM, 'The suitability of the mouse for children's use: a review of the literature', Journal of Computing in Childhood Education, 8 227-245 (1997) [C1]
Show 22 more journal articles

Review (1 outputs)

Year Citation Altmetrics Link
2006 Lane AE, 'The science and fiction of autism', HEALTH (2006)
DOI 10.1177/1363459306070295
Edit

Grants and Funding

Summary

Number of grants 2
Total funding $28,436

Click on a grant title below to expand the full details for that specific grant.


20152 grants / $28,436

Expanding Occupational Therapy (OT) clinical placements to schools: feasibility, efficacy and sustainability.$26,936

Funding body: Mid North Coast Local Health District

Funding body Mid North Coast Local Health District
Project Team Associate Professor Alison Lane, Mrs Gjyn O'Toole, Ms Narelle Herbert
Scheme Hunter and Coast ICTN Research and Quality Improvement Small Grant
Role Lead
Funding Start 2015
Funding Finish 2015
GNo G1500755
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

International Meeting for Autism Research, Utah USA, 14-16 May 2015$1,500

Funding body: University of Newcastle - Faculty of Health and Medicine

Funding body University of Newcastle - Faculty of Health and Medicine
Project Team Associate Professor Alison Lane
Scheme Travel Grant
Role Lead
Funding Start 2015
Funding Finish 2016
GNo G1500544
Type Of Funding Internal
Category INTE
UON Y
Edit

Research Supervision

Number of supervisions

Completed0
Current1

Total current UON EFTSL

PhD0.7

Current Supervision

Commenced Level of Study Research Title / Program / Supervisor Type
2015 PhD Preliminary Investigation of Sensory Features and Early Signs of Autism Spectrum Disorder (ASD) in Pre-Term Infants in the First Year of Life
Occupational Therapy, Faculty of Health and Medicine, The University of Newcastle
Principal Supervisor
Edit

Associate Professor Alison Lane

Position

Associate Professor
School of Health Sciences
Faculty of Health and Medicine

Contact Details

Email alison.lane@newcastle.edu.au
Phone (02) 4921 5004
Fax (02) 4921 7053

Office

Room Hunter HB-05
Building Hunter Building
Location Callaghan
University Drive
Callaghan, NSW 2308
Australia
Edit