Molecular Pathogenesis

Course code PHAR6213Units 10Level 6000Faculty of Health and MedicineSchool of Biomedical Sciences and Pharmacy

Introduces students to the molecular basis of disease and drug response. As knowledge of the genetic basis of disease increases so does the opportunities for drug targeting and patient specific-treatments. This course considers the two key elements - the genetics of disease and the genetics of drug response (pharmacogenomics).

Available in 2015

Callaghan CampusTrimester 1
Previously offered in 2014
ObjectivesStudents should:
1. Have a fundamental understanding of the molecular basis of disease;
2. Understand the molecular determinants of drug response;
3. Understand the molecular basis of cancer therapeutics;
4. Understand the impact of biotherapy on therapeutics, pharmaceutical industry and society; and
5. Gain basic understanding of the ethical issues related to the use of biotherapy.
Content1. Drug targets
2. Genomics
3. Proteomics
4. Pharmacogenetics
5. Pharmacogenomics
6. Monoclonal antibody therapeutics
7. Peptide-based therapeutics
8. Nucleic Acid therapeutics including anti-sense and gene-therapy
9. Cell-based therapeutics
10.SNP analysis
11.Ethical issues arising from the use of biotherapeutics
Replacing Course(s)Replaces PHAR6017 Molecular Pathogenesis 10 Units.
Industrial Experience0
Assumed KnowledgePHAR6123 Human Genomics and Biomolecular Analysis for Pharmacy.
Modes of DeliveryInternal Mode
Teaching MethodsProblem Based Learning
Assessment Items
Examination: FormalExamination paper held at the end of trimester. May comprise True/False, multiple choice and short answer questions and calculations.
Other: (please specify)Assessment may include Essays/written assignments as well as oral presentations on project tasks and generation of a report. Topics and dates will be advised in the course outline.
Other: (please specify)Students must achieve a passing grade in the final examination and all other assessment items to obtain a passing or higher grade in this course.

Students must demonstrate competency in the theoretical knowledge that forms part of the core competencies required of a pharmacist
Contact HoursLecture: for 3 hour(s) per Week for 10 weeks
Tutorial: for 2 hour(s) per Week for 10 weeks
Lecture: for 1 hour(s) per Week for 1 weeks
Compulsory Components
Requisite by EnrolmentThis course is only available to students enrolled in the Master of Pharmacy program.
Compulsory Program ComponentStudents can only enrol in PHAR6213 Molecular Pathogenesis if they have completed PHAR6123 Human Genomics and Biomolecular Analysis for Pharmacy
Timetables2015 Course Timetables for PHAR6213