Human Genomics and Biomolecular Analysis for Pharmacy

Description

Represents a blend between fundamental concepts and current issues in molecular medicine. Focuses on the relationships between structure, function and analysis of proteins and nucleic acids as applied to human disease and provides an introduction to modern concepts of genomic structure, function and analysis arising from the Human Genome project.

Availability

Callaghan Campus

  • Trimester 2 - 2015

Learning Outcomes

1. The nature of biopharmaceuticals and the role of biomolecular technologies in their development and application

2. Structural features of proteins and nucleic acids;

3. The inter-relationship between molecular structure and molecular function, and its relevance to therapeutics applications

4. The importance of molecular structure as it applies to fundamental biomedical analytical techniques;

5. New and emerging biopharmaceuticals and targets

6. Human genomic structure, function and analysis;

7. Basic Mendelian genetics;

8. Basic population genetics

Content

  1. Introduction to biopharmaceuticals
  2. Protein structure/function and handling
  3. Nucleic acid structure/function
  4. Gene manipulation and recombinant DNA technology
  5. Sources of biopharmaceuticals (expression systems)
  6. Downstream processing (recovery, purification and quantitation of proteins)
  7. Cell signaling
  8. Nucleic acid and cell-based therapeutics
  9. Identification of new targets
  10. Human Genome and Inheritance
  11. Genomic Abnormalities
  12. Genetic testing
  13. Human Genome Project
  14. Population Genetics
  15. Pharmacogenomics.

Requisites

This course is only available to students enrolled in the Master of Pharmacy program.

Assumed Knowledge

Entry level requirements for Master of Pharmacy

Assessment Items

Formal Examination: Examination - mid and end of trimester *

Presentation: Problem based learning oral presentation

Report: Genetics assessment

* This assessment has a compulsory requirement.

Compulsory Requirements

In order to pass this course, each student must complete ALL of the following compulsory requirements:

Course Assessment Requirements:

  • Formal Examination: Pass Requirement - Students must pass this assessment item to pass the course.

Contact Hours

Computer Lab

Face to Face On Campus 2 hour(s) per Week for 4 Weeks

Lecture

Face to Face On Campus 2 hour(s) per Week for 12 Weeks

Tutorial

Face to Face On Campus 17 hour(s) per Term

2 hours per week for 8 weeks and 1 hours per week for 1 week