Human Genomics and Biomolecular Analysis for Pharmacy

Course code PHAR6123Units 10Level 6000Faculty of Health and MedicineSchool of Biomedical Sciences and Pharmacy

Represents a blend between fundamental concepts and current issues in molecular medicine. Focuses on the relationships between structure, function and analysis of proteins and nucleic acids as applied to human disease and provides an introduction to modern concepts of genomic structure, function and analysis arising from the Human Genome project.

Available in 2015

Callaghan CampusTrimester 2
Previously offered in 2014
ObjectivesAt the end of the course, students should have an understanding of:
1. the nature of biopharmaceuticals and the role of biomolecular technologies in their development and application
2. structural features of proteins and nucleic acids;
3. the inter-relationship between molecular structure and molecular function, and its relevance to therapeutics applications
4. the importance of molecular structure as it applies to fundamental biomedical analytical techniques;
5. new and emerging biopharmaceuticals and targets
6. human genomic structure, function and analysis;
7. basic Mendelian genetics;
8. basic population genetics
Content1. Introduction to biopharmaceuticals
2. Protein structure/function and handling
3. Nucleic acid structure/function
4. Gene manipulation and recombinant DNA technology
5. Sources of biopharmaceuticals (expression systems)
6. Downstream processing (recovery, purification and quantitation of proteins)
7. Cell signaling
8. Nucleic acid and cell-based therapeutics
9. Identification of new targets
10. Human Genome and Inheritance
11. Genomic Abnormalities
12. Genetic testing
13. Human Genome Project
14. Population Genetics
15. Pharmacogenomics.
Replacing Course(s)Replacing PHAR6015 Human Genomics and Biomolecular Analysis for Pharmacy. 10 Units
Industrial Experience0
Assumed KnowledgeEntry level requirements for Master of Pharmacy
Modes of DeliveryInternal Mode
Teaching MethodsProblem Based Learning
Integrated Learning
Self Directed Learning
Computer Lab
Assessment Items
Examination: ClassMid trimester
Course learning objectives 1-4
Examination: FormalEnd of trimester
Course learning objectives 5-8
Other: (please specify)Problem based learning report
Course learning objectives 1-5
Genetics Assessment
Course learning objectives 6-8
Other: (please specify)Compulsory Course Component: Students must demonstrate competency in the theoretical knowledge that forms part of the core competencies required of a pharmacist. To do this students must show they are competent in all objectives by achieving a passing grade in the combined mid trimester and formal examination, and overall to be able to obtain a passing or higher grade in this course.
Contact HoursLecture: for 2 hour(s) per Week for 12 weeks
Tutorial: for 1 hour(s) per Week for 1 weeks
Tutorial: for 2 hour(s) per Week for 8 weeks
Computer Lab: for 2 hour(s) per Week for 4 weeks
Compulsory Components
Requisite by EnrolmentThis course is only available to students enrolled in the Master of Pharmacy program
Compulsory Course ComponentThe assessment components test a student's competency in one or more of the course learning objectives since these form part of the core competencies required of a pharmacist so students must:
1. achieve a passing grade in the combined mid trimester and formal examination.
Timetables2015 Course Timetables for PHAR6123