PHAR6123

Human Genomics and Biomolecular Analysis for Pharmacy

Faculty of Health School of Biomedical Sciences and Pharmacy

10 Units 6000 Level Course

Available in 2013

Callaghan Campus	Trimester 2

Previously offered in 2012, 2011, 2010, 2009, 2008

Represents a blend between fundamental concepts and current issues in molecular medicine. Focuses on the relationships between structure, function and analysis of proteins and nucleic acids as applied to human disease and provides an introduction to modern concepts of genomic structure, function and analysis arising from the Human Genome project.

Objectives

At the end of the course, students should have an understanding of:
1. the nature of biopharmaceuticals and the role of biomolecular technologies in their development and application
2. structural features of proteins and nucleic acids;
3. the inter-relationship between molecular structure and molecular function, and its relevance to therapeutics applications
4. the importance of molecular structure as it applies to fundamental biomedical analytical techniques;
5. new and emerging biopharmaceuticals and targets
6. human genomic structure, function and analysis;
7. basic Mendelian genetics;
8. basic population genetics

Content

1. Introduction to biopharmaceuticals
2. Protein structure/function and handling
3. Nucleic acid structure/function
4. Gene manipulation and recombinant DNA technology
5. Sources of biopharmaceuticals (expression systems)
6. Downstream processing (recovery, purification and quantitation of proteins)
7. Cell signaling
8. Nucleic acid and cell-based therapeutics
9. Identification of new targets
10. Human Genome and Inheritance
11. Genomic Abnormalities
12. Genetic testing
13. Human Genome Project
14. Population Genetics
15. Pharmacogenomics.

Replacing Course(s)

Replacing PHAR6015 Human Genomics and Biomolecular Analysis for Pharmacy. 10 Units

Transition

Industrial Experience

Assumed Knowledge

Entry level requirements for Master of Pharmacy

Modes of Delivery

Internal Mode

Teaching Methods

Problem Based Learning
Lecture
Integrated Learning
Self Directed Learning
Tutorial
Computer Lab

Assessment Items

Examination: Class	Mid trimester Course learning objectives 1-4
Examination: Formal	End of trimester Course learning objectives 5-8
Other: (please specify)	Problem based learning report Course learning objectives 1-5 Genetics Assessment Course learning objectives 6-8
Other: (please specify)	Students must demonstrate competency in the theoretical knowledge that forms part of the core competencies required of a pharmacist. To do this students must show they are competent in all objectives by achieving a passing grade in the combined mid trimester and formal examination, and overall to be able to obtain a passing or higher grade in this course.

Contact Hours

Tutorial: for 2 hour(s) per Week for 8 weeks
Lecture: for 2 hour(s) per Week for 12 weeks
Tutorial: for 1 hour(s) per Week for 1 weeks
Computer Lab: for 2 hour(s) per Week for 4 weeks

Compulsory Components

Requisite by Enrolment	This course is only available to students enrolled in the Master of Pharmacy program

Timetables