Pharmacogenomics and Personalised Health Care

Course code PHAR4201Units 10Level 4000Faculty of Health and MedicineSchool of Biomedical Sciences and Pharmacy

This course uses the cognitive and technical skills in molecular medicine and pharmacogenomincs learnt over the program to discuss advanced molecular basis of altered health states and drug response. As knowledge of the genetic basis of disease increases so does the opportunities for drug targeting and patient specific-treatments. This course considers the two key elements of the genetics of disease and the genetics of drug response (pharmacogenomics) and their inter-relationship.

Not available in 2015

ObjectivesAt the end of this course students will be able to:
1. Have an advanced understanding of the molecular basis of disease;
2. Demonstrate an understanding of the molecular determinants of drug response;
3. Discuss the molecular basis of cancer therapeutics;
4. Discuss the impact of biotherapy on therapeutics, pharmaceutical industry and society; and
5. Develop an understanding of the advanced ethical issues related to the use of biotherapy.
Content1. Drug targets
2. Genomics
3. Proteomics
4. Pharmacogenetics
5. Pharmacogenomics
6. Monoclonal antibody therapeutics
7. Peptide-based therapeutics
8. Nucleic Acid therapeutics including anti-sense and gene-therapy
9. Cell-based therapeutics
10. SNP analysis
11. Ethical issues arising from the use of biotherapeutics
Replacing Course(s)NA
Industrial Experience0
Assumed KnowledgeHUBS1202 Human Genomics and Biomolecular Analysis.
Modes of DeliveryInternal Mode
Teaching MethodsLecture
Assessment Items
Examination: ClassCourse Learning Objectives 1, 2, 3, 4, 5
Examination: FormalCourse Learning Objectives 1, 2, 3, 4, 5
Quiz - On-lineCourse Learning Objectives 1, 2, 3, 4, 5
Contact HoursLecture: for 2 hour(s) per Week for 8 weeks
Tutorial: for 2 hour(s) per Week for 8 weeks
Compulsory Components
Requisite by EnrolmentThis course is only available to students enrolled in the Bachelor of Pharmacy (Honours) program.
Compulsory Program ComponentPrior successful completion of HUBS1202 Human Genomics and Biomolecular Analysis.