Cancer, Critical Care and Palliation

Course code PHAR4101Units 10Level 4000Faculty of Health and MedicineSchool of Biomedical Sciences and Pharmacy

Presents the pathophysiology of altered health states and their management including both pharmacological and non-pharmacological interventions. Specific conditions covered in this course include oncology, haematology, palliation, emergency medicine and transplant medicine. The course considers aspects of pharmacy practice including a systematic review of prescription and non-prescription medications and Complementary and Alternate Medicines, which will address the quality use of medicines in the management of these conditions. Advanced drug information will be included in this course.

The course builds on student's existing knowledge and understanding of the physical pharmacy principles and provides students with an understanding of how these principles are applied to the preparation of cytotoxic drug products. The course builds also on the student's existing knowledge and understanding of the basic pharmacokinetic principles and provides students with an understanding of its application to advanced clinical pharmacokinetics. Population pharmacokinetics and toxicokinetics will be expanded on in this course.

Application of the knowledge developed in this course will be complemented by clinical skills training.

Not available in 2014

ObjectivesAt the end of this course students will be able to:
1. Describe the pathophysiology and management of conditions requiring critical care, including burns.
2. Describe the pathophysiology and management of conditions including neoplastic disorders, palliative care.
3. Describe the immunological basis of transplant medicine and the agents used in the management of transplant patients.
4. Gain an understanding of the signs, symptoms and complications of HIV-AIDS including opportunistic infections and systemic fungal disease; be aware of the pathogens involved, understand relevant diagnostic tests and be aware of first and second line infective therapy as well as non-pharmacological approaches to the management of these infections.
5. Use advanced drug information skills to describe the quality use of medicines' issues surrounding these therapeutic agents in the treatment of these conditions and continue to develop clinical skills and communication skills in the therapeutic management of these conditions.
6. Develop skills in the appropriate use of non-prescription products and advice on non-pharmacological treatment options in the management of these conditions.
7. Understand the techniques and processes involved in the preparation of cytotoxic drug products.
8. Apply advanced principles of pharmacodynamics and pharmacokinetics to clinical practice including population pharmacokinetics and toxicokinetics.
Content1. This course will cover the pathophysiology, therapeutic treatment and pharmacy practice issues in the management of:
- Emergency/ critical care patients (including burns, critical care therapy, fluid and electrolyte therapy and acid-base balance).
- Neoplastic disorders (including leukemias, lymphomas, breast cancer, lung cancer, gastrointestinal cancers, gynaecological cancers, prostrate cancer, skin cancers and melanomas and liver cancers).
- Palliative care.
- Haematological conditions including iron deficiency anaemia and megaloblastic anaemia.
- Clients undergoing transplants, including renal, heart-lung, bone-marrow and skin grafts.
2. The pathophysiology and principles for the treatment of HIV-AIDS, opportunistic infections and systemic fungal disease.
3. The concept of minor illness and major disease will be discussed, including the use of prescription and non-prescription products, including Complementary and Alternate Medicines. Non-pharmacological approaches to the management of these conditions and will also be discussed.
4. The course covers all pharmacokinetic considerations for therapeutic agents used in emergency medicine, oncology, toxicology and palliation. The application of clinical pharmacokinetics is covered thoroughly in this course.
5. Advanced drug information skills will be taught and applied in this course.
6. The preparation of cytotoxic drug products.
Replacing Course(s)NA
TransitionNA
Industrial Experience0
Assumed KnowledgePHAR3203 Clinical Pharmacotherapy 3
Modes of DeliveryInternal Mode
Teaching MethodsLecture
Integrated Learning
Self Directed Learning
Tutorial
Workshop
Assessment Items
Examination: ClassCourse Learning Objectives 1, 2, 3, 4, 5, 6, 7, 8
Essays / Written AssignmentsGroup Assignment
Course Learning Objectives 1, 2, 3, 4, 5, 6, 7, 8
Examination: FormalCourse Learning Objectives 1, 2, 3, 4, 5, 6, 7, 8
Quiz - On-lineCourse Learning Objectives 1, 2, 3, 4, 5, 6, 7, 8
Contact HoursLecture: for 3 hour(s) per Week for 8 weeks
Tutorial: for 2 hour(s) per Week for 8 weeks
Workshop: for 3 hour(s) per Week for 2 weeks
Compulsory Components
Compulsory Program ComponentPrior successful completion of PHAR1101 Introduction to Pharmacy and Formulation Sciences 1 and PHAR1201 Introduction to Pharmacy and Formulation Sciences 2.
Requisite by EnrolmentThis course is only available to students enrolled in the Bachelor of Pharmacy (Honours) program.