Mental and Neurological Health

Course code PHAR3103Units 10Level 3000Faculty of Health and MedicineSchool of Biomedical Sciences and Pharmacy

Presents the pathophysiology of altered health states and their management including both pharmacological and non-pharmacological interventions. Specific conditions covered in this course include neurological and mental health conditions, including head injuries as well as infectious diseases affecting the CNS. Concepts around the use of illicit drugs and drug abuse are also covered in this course. The course considers aspects of pharmacy practice including a systematic review of prescription and non-prescription medications and Complementary and Alternate Medicines, which will address the quality use of medicines in the management of these conditions.

The course builds on student's existing knowledge and understanding of the physical pharmacy principles and provides students with an understanding of how these principles are applied to the preparation of dosage formulations used in the management of conditions affecting the neurological system and mental health conditions. The stability of these drug products and factors influencing the storage and shelf life of products is included in this course. The clinical application of depot injections and wafer formulations will be discussed and expanded upon in this course.

Pharmacokinetic and Pharmacodynamic considerations in conditions affecting the neurological system and mental health conditions are covered including therapeutic drug monitoring, clinically significant pharmacokinetic drug interactions and advanced concepts in drug metabolism.

Application of the knowledge developed in this course will be complemented by clinical skills training.

Not available in 2014

ObjectivesAt the end of this course students will be able to:
1. Describe the pathophysiology and management (pharmacological and non-pharmacological) of conditions affecting the neurological system and mental health conditions.
2. Describe the pathophysiology and pharmacology of illicit drugs and understand the principles underlying the misuse of non-prescription and prescription medications.
3. Gain an understanding of the signs, symptoms and complications of CNS infections including meningitis, be aware of the pathogens involved, understand relevant diagnostic tests and be aware of first and second line infective therapy as well as non-pharmacological approaches to the management of these infections.
4. Describe the quality use of medicines' issues surrounding these therapeutic agents in the treatment of these conditions and continue to develop clinical skills and communication skills in the therapeutic management of these conditions.
5. Develop skills in the appropriate use of non-prescription products and advice on non-pharmacological treatment options in the management of these conditions.
6. Describe the formulation and manufacture of dosage formulations used in conditions affecting the neurological system and mental health conditions including long acting formulations such as depot injections and HBS dosage forms, as well as wafer formulations.
7. Describe the role of pharmacodynamics and pharmacokinetic factors that need to be considered in conditions affecting the neurological system and mental health conditions including therapeutic drug monitoring, clinically significant pharmacokinetic drug interactions and advanced concepts in drug metabolism.
Content1. This course will cover the pathophysiology, therapeutic management (pharmacological and non-pharmacological ) and pharmacy practice issues in the management of:
- Neurological conditions (including headache, seizures disorders, neurodegenerative disorders and pain management).
- Mental health conditions (including anxiety, schizophrenia, depression, drug addition, attention deficit hyperactivity disorder and sleep disorder).
- Head injury.
2. The pathophysiology and principles for the management of infectious diseases affecting the CNS including meningitis.
3. The concept of minor illness and major disease will be discussed, including the use of prescription and non-prescription products, including Complementary and Alternate Medicines. Non-pharmacological approaches to the management of these conditions will also be discussed.
4. The pathophysiology and pharmacology of illicit drugs and principles underlying the misuse of non-prescription and prescription medications:
- Intoxication and overdose of licit and illicit drugs.
- Drug addiction and physical dependence arising from the regular use of prescription and non-prescription medications.
- Health problems, social problems and criminal activity associated with the use and misuse of illicit drugs, non-prescription and prescription medications.
5. The course covers advanced concepts in formulation development and design of preparations used in mental health and neurological conditions:
- Sterile products, aseptic technique, microbial contamination, spoilage and preservation, principles of sterilisation and storage considerations.
- Advanced dispensing and compounding skills in understanding the underlying principles of long acting preparations such as depot injections and HBS dosage forms.
- Wafer formulations.
6. The course covers all pharmacokinetic and pharmacodynamics considerations for therapeutic agents used in the management of conditions affecting the neurological system and mental health including therapeutic drug monitoring, clinically significant pharmacokinetic/pharmacodynamic drug interactions and the clinical application of advanced concepts in drug metabolism, such as auto-induction and non-linear kinetics.
Replacing Course(s)NA
TransitionNA
Industrial Experience0
Assumed KnowledgePHAR2204 Clinical Pharmacotherapy 1
Modes of DeliveryInternal Mode
Teaching MethodsLecture
Integrated Learning
Self Directed Learning
Tutorial
Workshop
Assessment Items
Examination: ClassCourse Learning Objectives 1, 2, 3, 4, 5, 6, 7
Essays / Written AssignmentsGroup Assignment
Course Learning Objectives 1, 2, 3, 4, 5, 6, 7
Examination: FormalCourse Learning Objectives 1, 2, 3, 4, 5, 6, 7
Quiz - On-lineCourse Learning Objectives 1, 2, 3, 4, 5, 6, 7
Contact HoursLecture: for 3 hour(s) per Week for 10 weeks
Tutorial: for 2 hour(s) per Week for 10 weeks
Workshop: for 3 hour(s) per Week for 1 weeks
Compulsory Components
Compulsory Program ComponentPrior successful completion of PHAR1101 Introduction to Pharmacy and Formulation Sciences 1 and PHAR1201 Introduction to Pharmacy and Formulation Sciences 2.
Requisite by EnrolmentThis course is only available to students enrolled in the Bachelor of Pharmacy (Honours) program.