Cardiovascular and Renal Health

Course code PHAR2102Units 10Level 2000Faculty of Health and MedicineSchool of Biomedical Sciences and Pharmacy

Presents the pathophysiology of altered health states and their management including both pharmacological and non-pharmacological interventions. Specific conditions covered in this course include cardiovascular and renal disease. The course considers aspects of pharmacy practice including a systematic review of prescription and non-prescription medications and Complementary and Alternate Medicines, which will address the quality use of medicines in the treatment of these conditions.

Pharmacokinetic considerations in conditions of the cardiovascular and renal system are covered including pharmacokinetic modelling: volume of distribution and protein binding and renal clearance. An introduction to dose regimen design and therapeutic drug monitoring will also be covered.

Application of the knowledge developed in this course will be complemented by clinical skills training.

Available in 2015

Callaghan CampusSemester 1
ObjectivesAt the end of this course students will be able to:
1. Describe the pathophysiology and management of cardiovascular and renal disease.
2. Gain an understanding of the signs, symptoms and complications of common infections affecting the cardiovascular system including endocarditis, be aware of the pathogens involved, understand relevant diagnostic tests and be aware of first and second line anti-infective therapy as well as non-pharmacological approaches to the management of these conditions.
3. Describe the pathophysiology and basic management principles of anaemia as a result of renal impairment.
4. Describe the quality use of medicines' issues surrounding these therapeutic agents in the treatment of these conditions and continue to develop clinical skills and communication skills in the therapeutic management of these conditions.
5. Describe the role of pharmacodynamics and pharmacokinetic factors as determinants of drug response in cardiovascular and renal conditions.
6. Understand the underlying principles of pharmacokinetic modelling; volume of distribution and protein binding; renal clearance; and basic underlying principles of dose regimen design and therapeutic drug monitoring.
Content1. This course will cover the pathophysiology, therapeutic treatment and pharmacy practice issues in the management of:
- Cardiovascular conditions (including hypertension, heart failure, angina, arrhythmias, clotting disorders, stroke).
- Renal disease.
- Anaemia of renal impairment.
- The pathophysiology and principles for the treatment of Endocarditis.
2. The concept of minor illness and major disease will be discussed, including the use of prescription and non-prescription products, including Complementary and Alternate Medicines. Non-pharmacological approaches to the management of these conditions will also be discussed.
3. The course covers all pharmacokinetic considerations for therapeutic agents used in the management of cardiovascular and renal conditions including:
- Pharmacokinetic modelling.
- Volume of distribution and protein binding.
- Clearance of substances by the kidney.
- Principles underlying dose regimen design.
- Application of therapeutic drug monitoring in the therapeutic management of patients.
Replacing Course(s)NA
TransitionNA
Industrial Experience0
Assumed KnowledgePHAR1101 Introduction to Pharmacy and Formulation Sciences 1 and PHAR1201 Introduction to Pharmacy and Formulation Sciences 2
Modes of DeliveryInternal Mode
Teaching MethodsCase Study
Lecture
Integrated Learning
Laboratory
Self Directed Learning
Tutorial
Assessment Items
Case StudiesCourse Learning Objectives 1, 2, 3, 4, 5, 6
Examination: ClassCourse Learning Objectives 1, 2, 3, 4, 5, 6
Examination: FormalCourse Learning Objectives 1, 2, 3, 4, 5, 6
Quiz - On-lineCourse Learning Objectives 5, 6
Contact HoursLecture: for 3 hour(s) per Week for 12 weeks
Tutorial: for 2 hour(s) per Week for 12 weeks
Workshop: for 3 hour(s) per Week for 1 weeks
Compulsory Components
Requisite by EnrolmentThis course is only available to students enrolled in the Bachelor of Pharmacy (Honours) program.
Compulsory Program ComponentPrior successful completion of PHAR1101 Introduction to Pharmacy and Formulation Sciences 1 and PHAR1201 Introduction to Pharmacy and Formulation Sciences 2.
Timetables2015 Course Timetables for PHAR2102