Introduction to Pharmacy and Formulation Sciences 2

Description

Provides students with an understanding of the physical pharmacy principles applied to the preparation of liquid and semi-solid dosage forms. This includes the principles applied to solutions, suspensions and emulsions, including surface tension, interfacial phenomena, surfactants, adsorption and pH. An introduction to concepts around stability/degradation and storage/preservation will also be explored. The course builds on existing knowledge in pharmaceutics looking at veterinary compounding and manufacture.

An introduction to the basic concepts of pharmacology and how they are applicable to the practice of pharmacy is covered, including receptor pharmacology and an introduction to the autonomic nervous system. Basic pharmacokinetic principles are introduced and the link between pharmacokinetics and pharmacodynamics is explored.

Availability

Callaghan Campus

  • Semester 2 - 2015

Learning Outcomes

1. Describe the physiochemical factors affecting solutions, suspensions and emulsions.

2. Describe the use of medicines in veterinary practice and the principles of veterinary compounding and manufacture.

3. Understand the basic principles of stability and degradation.

4. Understand the basic principles of storage and preservation.

5. Identify the factors influencing the rate and extent of dissolution of a drug.

6. Describe the different types of polyphasic liquid and semi-solid dosage forms used in therapeutics.

7. Discuss the influence of chemical properties of drugs and excipients on the physicochemical properties of liquid dosage forms.

8. Describe the use of pharmaceutical excipients in dosage form design.

9. Describe the application of the basic pharmacological concepts in the management of patients.

10. Describe the basic ADME (absorption, distribution, metabolism and excretion) principles of pharmacokinetics and pharmacodynamics.

11. Discuss how pharmacodynamics and pharmacokinetics are interrelated.

Content

  1. Solubility and factors influencing dissolution.
  2. Biopharmaceutical importance of particle size.
  3. Osmotic properties of drug solutions.
  4. Surface and interfacial properties of surfactants.
  5. Emulsions, suspensions and other dispersions.
  6. Diffusion.
  7. Rheology.
  8. Excipients including preservatives.
  9. Key principles of surface activity, preservation of multiphase systems, adsorption and rheology of pharmaceutical systems.
  10. An introduction to the basic concepts of pharmacology and how they apply to pharmacy, including an introduction to receptor pharmacology.
  11. The pharmacology of the autonomic nervous system.
  12. The absorption, distribution, metabolism and excretion (ADME) principles of pharmacokinetics.
  13. An introduction to pharmacodynamics.
  14. Concepts in veterinary medicine, compounding and manufacture.

Requisites

This course is only available to students enrolled in the Bachelor of Pharmacy (Honours) program. Pre-requisite - successful completion of PHAR1101

Assumed Knowledge

PHAR1101 Introduction to Pharmacy and Formulation Sciences 1

Assessment Items

Formal Examination: Formal Exam *

Practical Demonstration: Calculations assessment

Practical Demonstration: Extemporaneous dispensing/ Practical Assessments

Practical Demonstration: Peer assessment and self-assessment

Project: Projects

In Term Test: Examination: Mid-Semester

Quiz: Quiz - Class

* This assessment has a compulsory requirement.

Compulsory Requirements

In order to pass this course, each student must complete ALL of the following compulsory requirements:

Course Assessment Requirements:

  • Formal Examination: Pass Requirement - Students must pass this assessment item to pass the course.

Pre-Placement Requirements:

  • First Aid Certificate - students must complete a First Aid Certificate issued by an approved provider.
  • NSW Health Verification Requirements - Students must complete NSW Health Department requirements for students to attend placements in NSW Health facilities.

Contact Hours

Lecture

Face to Face On Campus 2 hour(s) per Week for 12 Weeks

Workshop

Face to Face On Campus 3 hour(s) per Week for 12 Weeks