Human Infection and Immunity 2


This course provides integrated learning between the areas of microbiology, virology and immunology that builds on the knowledge developed in HUBS2601. Students will study advanced topics in microbiology: bacterial and viral pathogenesis, molecular methods of diagnosis and characterisation, replication strategies, treatment and prevention; and Immunology: haematopoiesis, innate and adaptive (cell-mediated and humoral) responses and autoimmunity.

The course is organised as a series of modules, which include problem based tutorials, lectures and practical classes. This course prepares students for a career in laboratory-based research in the biomedical sciences, particularly in areas that focus on microbial infection, immune mediated defence against infection and immunopathological processes that affect the health of the global community.


Callaghan Campus

  • Semester 1 - 2015

Learning Outcomes

1. Describe the pathogenesis of microbial and viral infections and apply this knowledge to any specific infectious disease.

2. Demonstrate knowledge of the utilisation of contemporary biomedical and molecular techniques to diagnose and characterise infectious microbes and in the development of new diagnostics, prevention and treatment strategies for infectious diseases.

3. Describe at an advanced level human immunity and the development of immune responses that are important in the prevention and development of disease.

4. Demonstrate how to research topics, seek out information and solve problems in microbiology and immunology.

5. Demonstrate practical skills necessary to conduct laboratory-based investigations in microbiology and immunology.

6. Analyse, discuss and present laboratory-based data and researched scientific information in written and oral forms of communication.


Bacteriology: This is an advanced course in bacteriology that is designed to investigate the high level understanding of host: pathogen relationships, diagnosis and characterisation of infection, vaccination and chemotherapy of infection, using specific examples. At the end of this module students will have an advanced understanding of the important basic and clinical concepts of bacteriology including:

  1. Investigation of a specific pathogenic bacterial infection
  2. Current concepts in diagnosis and characterisation
  3. Vaccination against bacteria
  4. Antibiotics and resistance
  5. Diagnosis, characterisation, vaccination and treatment of pneumococcal infection
  6. Listeria monocytogenes
  7. Research in bacteriology

Virology: The content in this module is designed to provide an overview of the replication strategies employed by different viruses and how they contribute to the mechanisms of viral pathogenesis. Students will then develop an understanding of how this knowledge can be used to develop specific control and treatment strategies against specific viruses that are important in human disease such as retroviruses, positive and negative sense RNA viruses, and small, medium and large sized DNA viruses. This module concludes by covering the antiviral responses, how viruses have adapted to overcome these responses and treatment/prevention strategies employed against viruses based on our knowledge of viral replication and pathogenesis.

Immunology: This module of the course uses the knowledge about microbiology and virology detailed above, and expands on the immunological responses to human infection. Topics include:

  1. Immune System Overview
  2. Bone Marrow/Haematopoiesis
  3. Innate Immune Response
  4. Inflammation/epithelial barrier
  5. T-cell subsets: Asthma, allergy and microRNA
  6. Auto-immunity
  7. Immunodeficiencies

Replacing Course(s)

This course replaces the following course(s): HUBS3206. Students who have successfully completed HUBS3206 are not eligible to enrol in HUBS3602.

Assumed Knowledge

HUBS2601 Human Infection and Immunity 1 or equivalent.

Assessment Items

Written Assignment: Major Assessment

Presentation: Oral Presentations

Formal Examination: Formal Exam *

Tutorial / Laboratory Exercises: Laboratory Exercises

* This assessment has a compulsory requirement.

Compulsory Requirements

In order to pass this course, each student must complete ALL of the following compulsory requirements:

Course Assessment Requirements:

  • Formal Examination: Pass Requirement - Students must pass this assessment item to pass the course. - Students must pass both the formal examination AND continual assessment in order to be able to pass the course overall.

Contact Hours


Face to Face On Campus 5 hour(s) per Week for 6 Weeks


Face to Face On Campus 2 hour(s) per Week for 12 Weeks


Face to Face On Campus 2 hour(s) per Week for 6 Weeks