Bioinformatics and Functional Genomics

Description

The completion of the Human Genome project has resulted in an explosion of genetic information and the development of high throughput techniques for sequencing DNA and proteins and looking at their expression profiles in different cell types. New computational tools for seeking, storing and analysing this information have also been developed. The challenge is to use the information stored in databases to solve biological problems and to inform hypothesis generation and future experiments. This course will provide an introduction to biological databases, with particular emphasis on both transcriptomics and proteomics, and how to search and use the information contained within them.

Availability

Callaghan Campus

  • Semester 1 - 2015

Learning Outcomes

1. Demonstrate knowledge of the extent of international biological databases and use them to investigate important research questions in genetics and the life sciences,

2. Use the knowledge and skills gained to logically, critically and creatively analyse real-life questions in genetics and the life sciences,

3. Work individually and collaboratively to solve research problems and acquire, organise and present information.

Content

This course will cover topics in bioinformatics and functional genomics including:

  1. Introduction to biological databases
  2. Using biological databases
  3. Functional genomics and analysis at the nucleotide level
  4. Proteomics and analysis at the post-translational level
  5. Using database analysis to infer relationships, to analyse expression patterns and molecular interactions

Assumed Knowledge

HUBS1202 Human Genomics and Biomolecular Analysis, HUBS2206 Human Biochemistry and Cell Biology and HUBS2209 Human Molecular Science or equivalent.

Assessment Items

In Term Test: Mid Semester Exam

Formal Examination: Final Exam

Project: Assignment

Presentation: Group oral presentation

Contact Hours

Computer Lab

Face to Face On Campus 2 hour(s) per Week for 11 Weeks

A mid term examination will be scheduled out of lecture time.

Lecture

Face to Face On Campus 27 hour(s) per Term

2 hours per week for 12 weeks and 3 hour per week for 1 week