Human Infection and Immunity 1


This course will build on the knowledge gained in the Year 1 Human Bioscience course: HUBS1404 Biomedical Science Part 2. Students will learn general principles of infection and immunity including the growth and metabolism of human microbial pathogens, mechanisms of microbial pathogenesis and infection control strategies. Students will also learn about host defence mechanisms to combat microbial infections.



  • Semester 1 - 2017

Learning Outcomes

On successful completion of the course students will be able to:

1. Describe the basic structures and growth characteristics of bacteria and viruses.

2. Demonstrate knowledge of contemporary biomedical and molecular techniques to diagnose and characterize infectious microbes.

3. Describe prevention and treatment strategies for infectious diseases.

4. Describe human immunity and the development of immune responses that are important in the prevention and development of disease.

5. Demonstrate how to research topics, seek out information and solve problems in microbiology and immunology.

6. Demonstrate practical skills necessary to conduct laboratory-based investigations in microbiology and immunology.

7. Analyse, discuss and present laboratory-based data and scientific information in written and oral forms of communication.



  1. Microbial diversity and structure
  2. Bacterial nutrition, metabolism, growth and study
  3. Bacterial genetics and evolution
  4. Bacterial virulence factors and their regulation,
  5. Pathogenicity islands secretion systems
  6. Microbial pathogenicity and epidemiology
  7. Mechanisms of bacterial pathogenicity


  1. Understand virus structure and what makes them different to eukaryotes/prokaryotes. Brief understanding of methods of diagnosis
  2. Broad understanding of the classification of different viruses that are important to human disease
  3. Broad understanding of different replication strategies employed by different viruses
  4. Understand how viruses alter cells to cause disease (i.e. Affect on host cells, changes in host immunity, tissue tropism, pathogenesis etc)
  5. Understand how vaccines work, how they are designed and the advantages/dis-advantages of the different types of vaccines (e.g. attenuated Vs killed)
  6. Understand the different targets of antiviral drugs. As well as understand how and why are these antivirals are designed to be specific to viruses
  7. Comprehensive review of a number of important gastrointestinal viruses and respiratory viruses


  1. Immune System: Structure & Components
  2. Innate Immunity (1): First Line of Defence
  3. Innate Immunity (2): Induced Response
  4. Adaptive Immunity (1): Antigen Presentation
  5. Adaptive Immunity (2): T-cell/ B-cell activation & function
  6. Cytokines/Chemookines & Their Receptors: Role in coordinating the immune response
  7. Antibodies/Complement
  8. The Immune System & Disease: Asthma & Allergy  


This course is only available to students enrolled in the Bachelor of Biomedical Science or Bachelor of Pharmacy (Honours) programs.

Assumed Knowledge

HUBS1403 Biomedical Science Part 1 and HUBS1404 Human Bioscience Part 2 or equivalent

Assessment Items

In Term Test: Mid semester test

Formal Examination: Final exam

Tutorial / Laboratory Exercises: Laboratory reports

Contact Hours



Face to Face On Campus 4 hour(s) per Week for 6 Weeks

A 1 hour examination will be scheduled during semester.


Face to Face On Campus 2 hour(s) per Week for 12 Weeks

A 1 hour examination will be scheduled during semester.


Face to Face On Campus 1 hour(s) per Week for 12 Weeks