HUBS2601
10 units
2000 level
Course handbook
Description
This course will build on the knowledge gained in the Year 1 Human Bioscience course: HUBS1404 Biomedical Science Part 2. Students will learn general principles of infection and immunity including the growth and metabolism of human microbial pathogens, mechanisms of microbial pathogenesis and infection control strategies. Students will also learn about host defence mechanisms to combat microbial infections.
Availability2024 Course Timetables
Callaghan
- Semester 1 - 2024
Learning outcomes
On successful completion of the course students will be able to:
1. Describe the basic structures and growth characteristics of bacteria and viruses.
2. Demonstrate knowledge of contemporary biomedical and molecular techniques to diagnose and characterize infectious microbes.
3. Describe prevention and treatment strategies for infectious diseases.
4. Describe human immunity and the development of immune responses that are important in the prevention and development of disease.
5. Demonstrate how to research topics, seek out information and solve problems in microbiology and immunology.
6. Demonstrate practical skills necessary to conduct laboratory-based investigations in microbiology and immunology.
7. Analyse, discuss and present laboratory-based data and scientific information in written and oral forms of communication.
Content
Bacteriology
- Microbial diversity and structure
- Bacterial nutrition, metabolism, growth and study
- Bacterial genetics and evolution
- Bacterial virulence factors and their regulation,
- Pathogenicity islands secretion systems
- Microbial pathogenicity and epidemiology
- Mechanisms of bacterial pathogenicity
Virology
- Understand virus structure and what makes them different to eukaryotes/prokaryotes. Brief understanding of methods of diagnosis
- Broad understanding of the classification of different viruses that are important to human disease
- Broad understanding of different replication strategies employed by different viruses
- Understand how viruses alter cells to cause disease (i.e. Affect on host cells, changes in host immunity, tissue tropism, pathogenesis etc)
- Understand how vaccines work, how they are designed and the advantages/dis-advantages of the different types of vaccines (e.g. attenuated Vs killed)
- Understand the different targets of antiviral drugs. As well as understand how and why these antivirals are designed to be specific to viruses
- Comprehensive review of a number of important gastrointestinal viruses and respiratory viruses
- For completeness there will also be a lecture on Eukaryotic Microorganisms
Immunology
- Immune System: Structure & Components
- Innate Immunity (1): First Line of Defence
- Innate Immunity (2): Induced Response
- Adaptive Immunity (1): Antigen Presentation
- Adaptive Immunity (2): T-cell/ B-cell activation & function
- Cytokines/Chemookines & Their Receptors: Role in coordinating the immune response
- Antibodies/Complement
- The Immune System & Disease: Asthma & Allergy
Requisite
This course is only available to students enrolled in the programs of
Bachelor of Pharmacy (Honours) [12328]
Bachelor of Biomedical Science [40097}
Bachelor of Biomedicine/Bachelor of Laws (Honours) [40280}
Assumed knowledge
HUBS1403 Biomedical Science Part 1 and HUBS1404 Human Bioscience Part 2 or equivalent
Assessment items
In Term Test: Mid semester tests
Compulsory Requirement: Pass requirement - Must pass this assessment item to pass the course.
Formal Examination: Final exam
Compulsory Requirement: Pass requirement - Must pass this assessment item to pass the course.
Tutorial / Laboratory Exercises: Laboratory reports
Compulsory Requirement: Pass requirement - Must pass this assessment item to pass the course.
Tutorial / Laboratory Exercises: Laboratory Skills
Contact hours
Semester 1 - 2024 - Callaghan
Laboratory-1
- Face to Face On Campus 3 hour(s) per week(s) for 4 week(s)
- Compulsory Requirement: Students must meet the compulsory attendance requirement.
Lecture-1
- Face to Face On Campus 27 hour(s) per term
Lecture-2
- Face to Face On Campus 1 hour(s) per week(s) for 2 week(s)
- Exams
Tutorial-1
- Face to Face On Campus 1 hour(s) per week(s) for 11 week(s)
Course outline
Course outline not yet available.
The University of Newcastle acknowledges the traditional custodians of the lands within our footprint areas: Awabakal, Darkinjung, Biripai, Worimi, Wonnarua, and Eora Nations. We also pay respect to the wisdom of our Elders past and present.