Human Pathophysiology


Provides an introduction to the concept of human disease and the pathophysiological mechanisms underlying the causes. Students will be provided with an introduction to pathophysiology of the immune, nervous, endocrine, skeletal, gastrointestinal, renal, vascular and respiratory systems. Associated pathologies of these systems will be introduced and explored.



  • Semester 1 - 2015


  • Semester 1 - 2015

Learning Outcomes

1. Develop an understanding of the concept of human disease.

2. Develop an understanding of the pathology and pathophysiology associated with disorders of the immune, nervous, endocrine, skeletal, renal, respiratory, gastrointestinal & cardiovascular systems.

3. Knowledge concerning the pathophysiological mechanisms and processes underlying human diseases


Students will initially be introduced to the concepts of disease and to the mechanisms by which cells undergo injury and adapt to such insult.
This will be followed by a module comprising an overview of immune effector function, inflammation and hypersensitivity, immune responses to pathogenic agents, autoimmunity and immunodeficiency. An introduction to neoplastic disease will complete the first module.

The second module will consider pathophysiological mechanisms underlying disorders of the gastrointestinal tract including hepatobiliary disease.

Module three explores cardiovascular disease and includes consideration of the consequences of ischaemic heart disease, heart failure, disorders of electroconduction and common vascular disorders.

Module four involves the respiratory system and will focus on acute pulmonary syndromes, restrictive and obstructive disease.

Module five will discuss renal pathophysiology and focus on aspects of acute and chronic renal failure and some common diseases that affect kidney function.

Module six considers endocrine disorders, in particular the pathophysiology of diabetes mellitus.

Module seven will explore the mechanisms underlying nervous system dysfunction, including the autonomic nervous system, at both the cellular and systems level as occurs in stroke, space occupying lesions, degenerative disorders and with injury to peripheral and central elements of the nervous system.

Review of Progress

This course is a compulsory program requirement for students in the following program(s):

In addition to meeting the University's overall requirements for academic progression, students enrolled in these program(s) must satisfactorily complete this course in order to progress in their program.

Assumed Knowledge

HUBS1403 Biomedical Sciences Part 1 and HUBS1404 Biomedical Science Part 2 OR HUBS1401 Human Bioscience 1A and HUBS1402 Human Bioscience 1B or equivalent

Assessment Items

In Term Test: Intra-semester exams (x2)

Formal Examination: Final exam

Contact Hours


Face to Face On Campus 3 hour(s) per Week for 12 Weeks

Mid semester examinations will be timetabled during the week


Face to Face On Campus 1 hour(s) per Week for 12 Weeks