HUBS2505Human Pathophysiology

Course handbook

Description

This course provides an introduction to the concept of human disease and the pathophysiological mechanisms underlying the causes. Students will be provided with an introduction to pathophysiology of the immune, endocrine, circulatory, respiratory, gastrointestinal, musculoskeletal, renal and nervous systems. Associated pathologies of these systems will be introduced and explored.

Availability2024 Course Timetables

Learning outcomes

On successful completion of the course students will be able to:

1. Develop an understanding of the concept of human disease.

2. Develop an understanding of the pathology and pathophysiology associated with disorders of the immune, endocrine, circulatory, respiratory, gastrointestinal, musculoskeletal, renal and nervous systems.

3. Develop an understanding of the pathophysiological mechanisms and processes underlying human diseases.

Content

Students will initially be introduced to the concepts of disease, some basic terminology of pathophysiology and to the mechanisms by which cells undergo injury and adapt to such insult.

This will be followed by a module comprising an overview of infection and immune responses to pathogenic agents, inflammation and hypersensitivity, autoimmunity and immunodeficiency. Common endocrine disorders will also be discussed.

The second module will consider pathophysiological mechanisms underlying disorders of blood and the lymphatic system together with an introduction to mechanisms underlying neoplasms.

Module three explores cardiovascular disease and includes consideration of the consequences of structural abnormalities, disorders of electro-conduction, ischaemic heart disease, heart failure and common vascular disorders.

Module four involves the respiratory system and will focus on acute pulmonary syndromes, obstructive and restrictive disease.

Module five will discuss upper and lower gastrointestinal tract pathophysiology and will also examine disorders of the accessory organs of the digestive system - liver, pancreas and gall bladder.

Module six considers pathophysiological mechanisms underlying disorders of the musculoskeletal system. Renal pathophysiology including aspects of acute and chronic renal failure and some common diseases that affect kidney function will also be considered in this module.

Module seven will explore the mechanisms underlying pathophysiology of neurological dysfunction at both the cellular and systems level as occurs in stroke, space occupying lesions, degenerative disorders and with injury to peripheral and central elements of the nervous system.

Assumed knowledge

HUBS1403 Biomedical Sciences Part 1 and HUBS1404 Biomedical Science Part 2 OR HUBS1401 Human Bioscience

Assessment items

In Term Test: Intra-semester exams (x2)
Compulsory Requirement: Submit assessment item - Must submit this assessment to pass the course.

Formal Examination: Final exam
Compulsory Requirement: Submit assessment item - Must submit this assessment to pass the course.

Contact hours

Semester 1 - 2024 - Callaghan

Semester 1 - 2024 - Ourimbah

Course outline

• HUBS2505 - Semester 1, 2024 (All) (PDF, 294.5 KB)