Human Genomics and Biomolecular Analysis

Description

This course represents a blend between fundamental concepts and current issues in molecular medicine. The course focuses on the relationships between structure, function and analysis of Proteins and Nucleic Acids as applied to human disease and provides an introduction to modern concepts of Genomic structure, function and analysis arising from the Human Genome project.

Availability

Callaghan Campus

  • Semester 2 - 2015

Learning Outcomes

1. Fundamental understanding of the structural features of proteins and nucleic acids.

2. Understand the inter-relationship between molecular structure and molecular function

3. Understand the importance of molecular structure as it applies to fundamental biomedical analytical techniques

4. Understand human genomic structure, function and analysis

5. Understand basic Mendelian genetics

6. Gain basic laboratory skills as applied to the analysis of human disease.

7. Gain basic problem solving techniques.

Content

  1. Composition and structure of proteins, deoxyribonucleic acid (DNA) and ribonucleic acid (RNA).
  2. Relationship between the structure, function and analysis of proteins, DNA and RNA.
  3. Relationship between DNA sequence and protein structure and function.
  4. Recombinant DNA technology.
  5. Skills in methods of protein, DNA and RNA isolation, analysis and interpretation of data in relation to the diagnosis of human disease.
  6. Composition and structure of the human genome
  7. The genetic basis of disease
  8. Relationship between genome structure and function
  9. Genome replication
  10. Genome mapping by genetic and physical techniques
  11. Genome mutation and recombination in human development and disease.

Requisites

This course is only available to students enrolled in the Bachelor of Biomedical Science or Bachelor of Pharmacy (Honours) programs.

Assessment Items

In Term Test: Intra-semester written tests (x2) *

Tutorial / Laboratory Exercises: Laboratory practice test

Tutorial / Laboratory Exercises: Laboratory assessments (x3)

Portfolio: Medical genetics computer laboratory portfolio

Presentation: Group oral presentation task

Formal Examination: Final written examination *

* This assessment has a compulsory requirement.

Compulsory Requirements

In order to pass this course, each student must complete ALL of the following compulsory requirements:

General Course Requirements:

  • Tutorial: Attendance Requirement - Students must attend a minimum number of these sessions. - Students must achieve a satisfactory level of attendance at tutorials.
  • Laboratory: Attendance Requirement - Students must attend a minimum number of these sessions. - Students must achieve a satisfactory level of attendance at laboratory sessions.
  • Computer Lab: Attendance Requirement - Students must attend a minimum number of these sessions. - Students must achieve a satisfactory level of attendance at computer labs.

Course Assessment Requirements:

  • In Term Test: Minimum Grade / Mark Requirement - Students must obtain a specified minimum grade / mark in this assessment item to pass the course. - Students must achieve a passing grade in the combined mini tests and formal examination
  • Formal Examination: Minimum Grade / Mark Requirement - Students must obtain a specified minimum grade / mark in this assessment item to pass the course. - Students must achieve a passing grade in the combined mini tests and formal examination

Contact Hours

Computer Lab

Face to Face On Campus 3 hour(s) per Week for 6 Weeks

Laboratory

Face to Face On Campus 3 hour(s) per Week for 6 Weeks

Lecture

Face to Face On Campus 25 hour(s) per Term

Tutorial

Face to Face On Campus 2 hour(s) per Week for 7 Weeks