HUBS1202

Human Genomics and Biomolecular Analysis

10 Units 1000 Level Course

Available in 2014

Callaghan Campus Semester 2

Previously offered in 2013, 2012, 2011, 2010, 2009, 2008, 2007, 2006, 2005, 2004

This course represents a blend between fundamental concepts and current issues in molecular medicine. The course focuses on the relationships between structure, function and analysis of Proteins and Nucleic Acids as applied to human disease and provides an introduction to modern concepts of Genomic structure, function and analysis arising from the Human Genome project.

Objectives 1. Fundamental understanding of the structural features of proteins and nucleic acids.
2. Understand the inter-relationship between molecular structure and molecular function
3. Understand the importance of molecular structure as it applies to fundamental biomedical analytical techniques
4. Understand human genomic structure, function and analysis
5. Understand basic Mendelian genetics
6. Gain basic laboratory skills as applied to the analysis of human disease.
7. Gain basic problem solving techniques.
Content 1. Composition and structure of proteins, deoxyribonucleic acid (DNA) and ribonucleic acid (RNA).
2. Relationship between the structure, function and analysis of proteins, DNA and RNA.
3. Relationship between DNA sequence and protein structure and function.
4. Recombinant DNA technology.
5. Skills in methods of protein, DNA and RNA isolation, analysis and interpretation of data in relation to the diagnosis of human disease.
6. Composition and structure of the human genome
7. The genetic basis of disease
8. Relationship between genome structure and function
9. Genome replication
10. Genome mapping by genetic and physical techniques
11. Genome mutation and recombination in human development and disease.
Replacing Course(s) HUBS1201 Biomolecular Analysis (10 units)
Transition Not applicable
Industrial Experience 0
Assumed Knowledge None. This is a self contained level 1 course
Modes of Delivery Internal Mode
Teaching Methods Problem Based Learning
Lecture
Integrated Learning
Laboratory
Tutorial
Computer Lab
Assessment Items
Examination: Formal End of semester examination.

Students must perform satisfactorily in the formal assessment in order to pass the course overall.
Group/tutorial participation and contribution Attendance: Students will be required to achieve a satisfactory level of attendance at tutorials, computer labs and laboratory sessions as they are core objectives of the course.
Laboratory Exercises Laboratory reports and in-lab assignments
Other: (please specify) Computer Tasks
Medical Genetics Assessment
Contact Hours Computer Lab: for 2 hour(s) per Week for 1 weeks
Laboratory: for 3 hour(s) per Week for 6 weeks
Tutorial: for 2 hour(s) per Week for 6 weeks
Computer Lab: for 1 hour(s) per Week for 2 weeks
Lecture: for 2 hour(s) per Week for 12 weeks
Computer Lab: for 3 hour(s) per Week for 6 weeks
Compulsory Components
Requisite by Enrolment Students enrolled in the Bachelor of Biomedical Science program
Timetables 2014 Course Timetables for HUBS1202