Human Genomics and Biomolecular Analysis

Course code HUBS1202Units 10Level 1000Faculty of Health and MedicineSchool of Biomedical Sciences and Pharmacy

This course represents a blend between fundamental concepts and current issues in molecular medicine. The course focuses on the relationships between structure, function and analysis of Proteins and Nucleic Acids as applied to human disease and provides an introduction to modern concepts of Genomic structure, function and analysis arising from the Human Genome project.

Available in 2014

Callaghan CampusSemester 2
Previously offered in 2013, 2012, 2011, 2010, 2009, 2008, 2007, 2006, 2005, 2004
Objectives1. Fundamental understanding of the structural features of proteins and nucleic acids.
2. Understand the inter-relationship between molecular structure and molecular function
3. Understand the importance of molecular structure as it applies to fundamental biomedical analytical techniques
4. Understand human genomic structure, function and analysis
5. Understand basic Mendelian genetics
6. Gain basic laboratory skills as applied to the analysis of human disease.
7. Gain basic problem solving techniques.
Content1. Composition and structure of proteins, deoxyribonucleic acid (DNA) and ribonucleic acid (RNA).
2. Relationship between the structure, function and analysis of proteins, DNA and RNA.
3. Relationship between DNA sequence and protein structure and function.
4. Recombinant DNA technology.
5. Skills in methods of protein, DNA and RNA isolation, analysis and interpretation of data in relation to the diagnosis of human disease.
6. Composition and structure of the human genome
7. The genetic basis of disease
8. Relationship between genome structure and function
9. Genome replication
10. Genome mapping by genetic and physical techniques
11. Genome mutation and recombination in human development and disease.
Replacing Course(s)HUBS1201 Biomolecular Analysis (10 units)
TransitionNot applicable
Industrial Experience0
Assumed KnowledgeNone. This is a self contained level 1 course
Modes of DeliveryInternal Mode
Teaching MethodsProblem Based Learning
Lecture
Integrated Learning
Laboratory
Tutorial
Computer Lab
Assessment Items
Examination: ClassMid term Nucleic Acids and Protein examination
Course Learning Objectives: 1-5

Medical Genetics Assessment
Course Learning Objectives: 6-11
Examination: FormalEnd of semester examination.
Course Learning Objectives: 1-7

Compulsory Course Component: Students must achieve a passing grade in the combined class examinations and formal examination and overall to be able to obtain a passing or higher grade in this course. On achieving a passing grade, a final mark will be given in the course and it will be recorded that the student has satisfied the compulsory course component. Students will have feedback on their performance after the in-class examinations and will have had opportunities for remediation prior to the formal examination so students who fail to satisfy the compulsory course component will be awarded a zero mark and a FF grade, irrespective of their final numeric mark.
Group/tutorial participation and contributionCompulsory Course Component: Attendance: Students will be required to achieve a satisfactory level of attendance at tutorials, computer labs and laboratory sessions as they address core objectives for the course.
Students who miss a laboratory session, and have grounds for adverse circumstances, will be provided alternative arrangements to meet these objectives & complete the assessment.
Course Learning Objectives: 2-7
Laboratory ExercisesLaboratory reports and in-lab assignments
Course Learning Objectives: 2,6,7
Other: (please specify)Computer Tasks
Course Learning Objectives: 1-3
Presentations - GroupGroup Oral Presentation
Course Learning Objectives: 6-11
Contact HoursLaboratory: for 3 hour(s) per Week for 6 weeks
Lecture: for 2 hour(s) per Week for 12 weeks
Computer Lab: for 3 hour(s) per Week for 6 weeks
Tutorial: for 2 hour(s) per Week for 7 weeks
Lecture: for 1 hour(s) per Week for 1 weeks
Compulsory Components
Requisite by EnrolmentStudents enrolled in the Bachelor of Biomedical Science and Bachelor of Pharmacy (Honours) programs.
Compulsory Course ComponentIn order to demonstrate that they have fulfilled the course learning objectives students must:
1. satisfactorily pass the combined in class assessment and formal examination for the course and
2. achieve a satisfactory level of attendance at tutorials, computer labs and laboratory sessions.
Timetables2014 Course Timetables for HUBS1202