Bioinformatics and Statistical Genetics

Course code BIOS6110Units 10Level 6000Faculty of Health and MedicineSchool of Medicine and Public Health

Provides an introduction to the fields of bioinformatics and genetic epidemiology from a statistical point of view. Students will be taught how to apply appropriate statistical methods to the analysis of genetic data.
The course is offered in conjunction with the Biostatistics Collaboration of Australia (BCA)

Not available in 2014

Previously offered in 2011, 2010, 2009, 2006, 2005, 2004
ObjectivesOn completion students will:
1. have a basic understanding of modern genetics;
2. understand the implications of bioinformatics for epidemiology, gene discovery and studies of gene function;
3. be able to apply appropriate statistical methods to the analysis of genetic data from studies of human subjects, both family and population-based.
ContentThe first component of the course is an introduction to various topics of elementary molecular biology, which is fundamental to the analysis of genetics data. Conducting database searches (of DNA, RNA, amino acids and proteins databases) is one of the most common tasks in bioinformatics, so a grounding in these methods is provided.
Students will also be given a grounding in important probability/statistical models (Mendelian inheritance, Hardy-Weinberg equilibrium, crossing over, and map distance). Descriptions of the various types of genetic studies (linkage and family studies, linkage disequilibrium and population studies) will also be provided.
Replacing Course(s)N/A
Industrial Experience0
Assumed KnowledgeEpidemiology;
Mathematical Background for Biostatistics;
Principles of Statistical Inference;
Linear Models
Probability and Distribution Theory
Modes of DeliveryDistance Learning : Paper Based
Teaching MethodsSelf Directed Learning
Assessment Items
Essays / Written AssignmentsAssignments 60% (Three written assignments worth 20% each).
Take home exam worth 40%.
Contact HoursSelf Directed Learning: for 6 hour(s) per Week for Full Term
Compulsory Components
Requisite by EnrolmentThis course is only available to students enrolled in the Graduate Diploma in Medical Statistics or Master of Medical Statistics programs.